- Must visit
Buffalo AKG Art Museum
Buffalo’s flagship art museum, known for its strong modern and contemporary collection and major architectural expansion. A top choice for art lovers.
Cheapest price
$187
Average price
$256
Fastest journey
1 d 14 h 15 m
Average duration
1 d 20 h 45 m
Buses per day
3
Distance
2301 km
The best way to find a cheap bus ticket from San Antonio, TX to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Buffalo, NY will cost around $256 if you buy it on the day, but the cheapest tickets can be found for only $187.
Of the 3 buses that leave San Antonio, TX for Buffalo, NY on Tue, Jun 16, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 16 the direct buses cover the 2301 km distance in an average of 1 d 20 h 45 m but if you time it right, some buses will get you there in just 1 d 14 h 15 m .
On Tue, Jun 16 the slowest buses will take 2 d 4 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the train as it is the most popular option from San Antonio, TX to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $187. For those with little time consider booking a flight which can get you there in 4h 34m. The ticket price range depends on the travel mode: a bus costs an average of $187, and a train costs an average of $212.
Distance: 1429 miles (2301 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$347 Average price Cheapest | $705 Average price | $477 Average price | $332 Average price (fuel + tolls) |
39h 42m Average total duration 39h 12m Onboard + 30m Additional time* | 41h 48m Average total duration 41h 18m Onboard + 30m Additional time* | 7h 34m Average total duration Fastest 4h 34m Onboard + 3h 0m Additional time* | 24h 4m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Buffalo, NY:
A bus is $130 (€105) less than a flight for this route with tickets for a flight from San Antonio, TX to Buffalo, NY costing on average $477 (€387).
A bus is $358 (€291) less than a train for this route with tickets for a train from San Antonio, TX to Buffalo, NY costing on average $705 (€573).
Other travel options to Buffalo, NY take longer:
Bus takes on average 39h 12m.
Train takes on average 41h 18m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 08:15PM | Duration 44h00 | Departure days Tue | Cheapest price $187 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 08:40AM | Duration 55h25 | Departure days Sun | Cheapest price $218 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 08:45PM | Duration 42h30 | Departure days Sun | Cheapest price $473 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 08:45PM | Duration 38h15 | Departure days Mon | Cheapest price $235 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 04:55AM | Duration 64h10 | Departure days Fri | Cheapest price $498 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 10:30PM | Duration 52h00 | Departure days Wed, Thu | Cheapest price $373 |
Operator Greyhound | Departure Time 07:30PM | Arrival Time 11:30PM | Duration 52h00 | Departure days Mon | Cheapest price $346 |
The table below shows live departures for San Antonio, TX to Buffalo, NY buses for tomorrow, Monday, June 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:15 AM San Antonio, TX | 44h00 | 8:15 PM Buffalo, NY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to Buffalo, NY run on average 5 times per day, taking around 39h 12m. Cheap bus tickets for this journey start at $187 (€152) if you book in advance.
The earliest bus runs at 00:39, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 38h 15m.
Distance 1429 miles (2301 km) |
Average bus duration 39h 12m |
Cheapest ticket price $187 (€152) |
Buses per day 5 |
Fastest bus 38h 15m |
First bus 12:39 AM |
Last bus 11:20 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Buffalo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo trip today.
Buffalo’s flagship art museum, known for its strong modern and contemporary collection and major architectural expansion. A top choice for art lovers.
An important architectural museum complex and one of Frank Lloyd Wright’s masterpieces, offering deep insight into Prairie School design.
A regional history museum in a landmark 1901 Pan-American Exposition building, with exhibits on Buffalo, Erie County, and Western New York.
Buffalo’s revitalized waterfront district, popular for boardwalk walks, harbor views, events, and social-media-friendly public spaces.
A major Frederick Law Olmsted-designed park with scenic roads, the lake, gardens, and cultural institutions nearby. Ideal for walking and relaxing.
One of Buffalo’s best-known neighborhoods for strolling, lined with historic homes, local shops, and a lively but relaxed urban atmosphere.
Crispy chicken wings tossed in a buttery cayenne hot sauce, traditionally served with celery and blue cheese. Buffalo’s signature dish originated here and is the city’s must-try food.
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway seeds, usually served with horseradish and au jus. It is a classic Western New York sandwich strongly associated with BU
A regional confection made from airy honeycomb toffee coated in chocolate. Buffalo is especially known for it, and local chocolatiers have made it a beloved traditional sweet.
A long-running bistro on the West Side with a more refined atmosphere, known for consistently good American and European-inspired dishes. A solid option beyond tavern fare.
A classic Buffalo restaurant renowned for beef on weck, old-school service, and a traditional dining room atmosphere. One of the best-known places to try this regional specialty.
A beloved neighborhood tavern in a historic building, known for wings, hearty pub food, and a warm local atmosphere. Popular with both residents and visitors.
Moderate by U.S. standards. Hotels vary by season, while casual dining, coffee, and local transport are fairly affordable.
Tip 18-20% at restaurants if service is not included; 15-20% for taxis and rideshares. USD 1-2 per drink at bars, USD 1-2 per bag for hotel porters, and a few dollars daily for housekeeping.
Find answers to the most common questions about traveling from San Antonio, TX to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

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