- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
Cheapest price
$442
Average price
$442
Fastest journey
2 d 4 h
Average duration
2 d 4 h
Buses per day
1
Distance
2301 km
The best way to find a cheap bus ticket from San Antonio, TX to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Buffalo, NY will cost around $442 if you buy it on the day, but the cheapest tickets can be found for only $442.
Of the 1 buses that leave San Antonio, TX for Buffalo, NY on Thu, Jul 30, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 30 the direct buses cover the 2301 km distance in an average of 2 d 4 h but if you time it right, some buses will get you there in just 2 d 4 h .
On Thu, Jul 30 the slowest buses will take 2 d 4 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from San Antonio, TX to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $184. For those with little time consider booking a flight which can get you there in 4h 34m. The ticket price range depends on the travel mode: a bus costs an average of $184, and a train costs an average of $209.
Distance: 1429 miles (2301 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$342 Average price Cheapest | $695 Average price | $470 Average price | $327 Average price (fuel + tolls) |
39h 42m Average total duration 39h 12m Onboard + 30m Additional time* | 41h 48m Average total duration 41h 18m Onboard + 30m Additional time* | 7h 34m Average total duration Fastest 4h 34m Onboard + 3h 0m Additional time* | 24h 4m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Buffalo, NY:
A bus is $128 (€105) less than a flight for this route with tickets for a flight from San Antonio, TX to Buffalo, NY costing on average $470 (€387).
A bus is $353 (€291) less than a train for this route with tickets for a train from San Antonio, TX to Buffalo, NY costing on average $695 (€573).
Other travel options to Buffalo, NY take longer:
Bus takes on average 39h 12m.
Train takes on average 41h 18m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 08:15PM | Duration 44h00 | Departure days Tue | Cheapest price $184 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 08:40AM | Duration 55h25 | Departure days Sun | Cheapest price $214 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 08:45PM | Duration 42h30 | Departure days Sun | Cheapest price $466 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 08:45PM | Duration 38h15 | Departure days Mon | Cheapest price $231 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 04:55AM | Duration 64h10 | Departure days Fri | Cheapest price $490 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 10:30PM | Duration 52h00 | Departure days Wed, Thu | Cheapest price $367 |
Operator Greyhound | Departure Time 07:30PM | Arrival Time 11:30PM | Duration 52h00 | Departure days Mon | Cheapest price $340 |
The table below shows live departures for San Antonio, TX to Buffalo, NY buses for tomorrow, Thursday, July 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:30 PM San Antonio, TX | 52h00 | 10:30 PM Buffalo, NY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to Buffalo, NY run on average 5 times per day, taking around 39h 12m. Cheap bus tickets for this journey start at $184 (€152) if you book in advance.
The earliest bus runs at 00:39, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 38h 15m.
Distance 1429 miles (2301 km) |
Average bus duration 39h 12m |
Cheapest ticket price $184 (€152) |
Buses per day 5 |
Fastest bus 38h 15m |
First bus 12:39 AM |
Last bus 11:20 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
Find answers to the most common questions about traveling from San Antonio, TX to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Buffalo, NY buses use the San Antonio, N St Mary's St (Greyhound) to Cheektowaga, BNIA Drway & BNIA Terminal station pair, with some services arriving at Buffalo, NFTA Metro Center. Use this guide to compare San Antonio, TX and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need