- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
Cheapest price on Sep 14
€154
Average ticket price on Sep 14
€162
Fastest journey on Sep 14
1 d 14 h 15 m
Average journey duration on Sep 14
1 d 22 h 44 m
Buses on Sep 14
8
Distance
2301 km
The best way to find a cheap bus ticket from San Antonio, TX to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Buffalo, NY will cost around €162 if you buy it on the day, but the cheapest tickets can be found for only €154.
It's difficult to get from San Antonio, TX to Buffalo, NY without transferring at least 3 times.
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FlixBusOmio recommends booking the train as it is the most popular option from San Antonio, TX to Buffalo, NY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €350 For those with little time, consider booking a flight, which has an average total journey time of 7h 0m. Average ticket prices depend on the travel mode: a bus costs an average of €350, while a train costs an average of €1001.
Distance: 1429 miles (2301 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€350 Average price Cheapest | €1001 Average price | €605 Average price | €273 Average price (fuel + tolls) |
45h 44m Average total duration 45h 14m Onboard + 30m Additional time* | 41h 49m Average total duration 41h 19m Onboard + 30m Additional time* | 7h 0m Average total duration Fastest 5h 0m Onboard + 2h 0m Additional time* | 24h 4m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Buffalo, NY:
A bus is €255 less than a flight for this route with tickets for a flight from San Antonio, TX to Buffalo, NY costing on average €605.
A bus is €651 less than a train for this route with tickets for a train from San Antonio, TX to Buffalo, NY costing on average €1001.
Other travel options to Buffalo, NY take longer:
Train takes on average 41h 19m.
Bus takes on average 45h 14m.
Tickets start at around €350 compared to roughly €273 in fuel and tolls — a saving of about €-77.17. The journey takes 45h 14m versus 24h 4m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 08:25AM | Duration 54h20 | Departure days Everyday | Cheapest price €136 |
Operator Greyhound | Departure Time 01:30AM | Arrival Time 04:45PM | Duration 38h15 | Departure days Everyday | Cheapest price €115 |
Operator Greyhound | Departure Time 07:35AM | Arrival Time 04:40PM | Duration 56h05 | Departure days Everyday | Cheapest price €128 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 06:30PM | Duration 57h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €123 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 06:30PM | Duration 52h00 | Departure days Everyday | Cheapest price €121 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 04:40AM | Duration 56h25 | Departure days Everyday | Cheapest price €127 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 04:45PM | Duration 42h45 | Departure days Wed, Thu | Cheapest price €128 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 04:45PM | Duration 41h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €127 |
The table below shows live departures for San Antonio, TX to Buffalo, NY buses for today, Sunday, September 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 7:35 AM San Antonio, N St Mary's St (Greyhound), TX | 56h05 | 4:40 PM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 57h45 | 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 47h15 | 8:00 AM Buffalo, NFTA Metro Center | 5 transfers | |
· · · | 1:30 PM San Antonio, N St Mary's St (Greyhound), TX | 52h00 | 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
· · + FlixBus | 7:15 PM San Antonio, N St Mary's St (Greyhound), TX | 56h25 | 4:40 AM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
FlixBus+ · · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 41h50 | 4:45 PM Buffalo, NFTA Metro Center | 3 transfers | |
| Monday, September 14 | |||||
· · + FlixBus | 1:05 AM San Antonio, N St Mary's St (Greyhound), TX | 54h20 | 8:25 AM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
· · · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 38h15 | 4:45 PM Buffalo, NFTA Metro Center | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to Buffalo, NY run on average 7 times per day, taking around 45h 14m. Cheap bus tickets for this journey start at €290 if you book in advance.
The earliest bus runs at 00:39, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 34h 10m.
Distance 1429 miles (2301 km) |
Average bus duration 45h 14m |
Cheapest ticket price €290 |
Buses per day 7 |
Fastest bus 34h 10m |
First bus 12:39 AM |
Last bus 11:20 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
Find answers to the most common questions about traveling from San Antonio, TX to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Buffalo, NY buses use the San Antonio, N St Mary's St (Greyhound) to Cheektowaga, BNIA Drway & BNIA Terminal station pair, with some services arriving at Buffalo, NFTA Metro Center. Use this guide to compare San Antonio, TX and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Ticket office support is available at Buffalo, NFTA Metro Center.
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Here are some other resources that might have the information you need