- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from San Antonio, TX to Buffalo, NY
Showing times, prices and bookable tickets for Oct 29
Cheapest price on Oct 29
$198
Average ticket price on Oct 29
$211
Fastest journey on Oct 29
1 d 14 h 15 m
Average journey duration on Oct 29
1 d 22 h 55 m
Buses on Oct 29
8
Distance
2301 km
Cheap tickets
The best way to find a cheap bus ticket from San Antonio, TX to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Buffalo, NY will cost around $211 if you buy it on the day, but the cheapest tickets can be found for only $198.
Fast buses
It's difficult to get from San Antonio, TX to Buffalo, NY without transferring at least 3 times.
· · · 7:35 AM 56h05 San Antonio, N St Mary's St (Greyhound), TX 4:40 PM Cheektowaga, BNIA Drway & BNIA Terminal $198 1 One-way 4 transfers- · · ·
1:30 PM 52h00 San Antonio, N St Mary's St (Greyhound), TX 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal $199 1 One-way 4 transfers - · · ·
1:30 AM 38h15 San Antonio, N St Mary's St (Greyhound), TX 4:45 PM Buffalo, NFTA Metro Center $202 1 One-way 3 transfers - · · +
FlixBus7:15 PM 56h25 San Antonio, N St Mary's St (Greyhound), TX 3:40 AM Cheektowaga, BNIA Drway & BNIA Terminal $203 1 One-way 4 transfers - FlixBus · FlixBus+ ·
7:45 AM 47h15 San Antonio, Avenue A / Pearl Pkwy, TX 8:00 AM Buffalo, NFTA Metro Center $208 1 One-way 5 transfers
- · · ·
1:30 AM 38h15 San Antonio, N St Mary's St (Greyhound), TX 4:45 PM Buffalo, NFTA Metro Center $202 1 One-way 3 transfers - · · +
9:00 PM 42h45 San Antonio, N St Mary's St (Greyhound), TX 4:45 PM Buffalo, NFTA Metro Center $215 1 One-way 3 transfers - FlixBus · FlixBus+ ·
7:45 AM 47h15 San Antonio, Avenue A / Pearl Pkwy, TX 8:00 AM Buffalo, NFTA Metro Center $208 1 One-way 5 transfers - · · ·
1:30 PM 52h00 San Antonio, N St Mary's St (Greyhound), TX 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal $199 1 One-way 4 transfers - · · +FlixBus
1:05 AM 54h20 San Antonio, N St Mary's St (Greyhound), TX 8:25 AM Cheektowaga, BNIA Drway & BNIA Terminal $239 1 One-way 4 transfers
Journey information
Overview: Bus from San Antonio, TX to Buffalo, NY
USAUSA
Buses from San Antonio, TX to Buffalo, NY run on average 7 times per day, taking around 44h 18m. Cheap bus tickets for this journey start at $132 (€111) if you book in advance.
The earliest bus runs at 00:39, the last at 23:20. The fastest bus covers the 1429 miles (2301 km) distance in 34h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1429 miles (2301 km) |
Average bus duration 44h 18m |
Cheapest ticket price $132 (€111) |
Buses per day 7 |
Fastest bus 34h 10m |
First bus 12:39 AM |
Last bus 11:20 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your San Antonio, TX to Buffalo, NY trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Antonio, TX to Buffalo, NY.
Cheap bus tickets from San Antonio, TX to Buffalo, NY can start from as little as $132 (€111) when you book in advance. The average bus ticket price for San Antonio, TX to Buffalo, NY is $206 (€174) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from San Antonio, TX to Buffalo, NY leaves at 12:39 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Buffalo, NY leaves at 11:20 PM.
There are 7 buses a day from San Antonio, TX to Buffalo, NY which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
San Antonio, TX to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 08:25AM | Duration 54h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $188 |
Operator Greyhound | Departure Time 01:30AM | Arrival Time 04:45PM | Duration 38h15 | Departure days Everyday | Cheapest price $147 |
Operator Greyhound | Departure Time 07:35AM | Arrival Time 04:40PM | Duration 56h05 | Departure days Tue, Wed, Thu, Fri, Sun | Cheapest price $159 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 06:30PM | Duration 57h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $148 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 06:30PM | Duration 52h00 | Departure days Everyday | Cheapest price $147 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 04:40AM | Duration 56h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $152 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 04:45PM | Duration 42h45 | Departure days Wed, Thu | Cheapest price $159 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 04:45PM | Duration 42h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $152 |
Live departures
San Antonio, TX to Buffalo, NY bus times
The table below shows live departures for San Antonio, TX to Buffalo, NY buses for today, Wednesday, October 28. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · · | 1:30 PM San Antonio, N St Mary's St (Greyhound), TX | 52h00 | 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
| · · +FlixBus | 7:15 PM San Antonio, N St Mary's St (Greyhound), TX | 56h25 | 4:40 AM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
| · · + | 9:00 PM San Antonio, N St Mary's St (Greyhound), TX | 42h45 | 4:45 PM Buffalo, NFTA Metro Center | 3 transfers | |
| Thursday, October 29 | |||||
| · · +FlixBus | 1:05 AM San Antonio, N St Mary's St (Greyhound), TX | 54h20 | 8:25 AM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
| · · · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 38h15 | 4:45 PM Buffalo, NFTA Metro Center | 3 transfers | |
| · · · | 7:35 AM San Antonio, N St Mary's St (Greyhound), TX | 56h05 | 4:40 PM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
| FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 57h45 | 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal | 4 transfers | |
| FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 47h15 | 8:00 AM Buffalo, NFTA Metro Center | 5 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book San Antonio, TX to Buffalo, NY buses with Omio?
Greyhound as well as FlixBus offer buses services from San Antonio, TX to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Buffalo, NY.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from San Antonio, TX to Buffalo, NY.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Antonio, TX to Buffalo, NY.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from San Antonio, TX to Buffalo, NY.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Antonio, TX to Buffalo, NY.
Bus providers: Greyhound, FlixBus from San Antonio, TX to Buffalo, NYYou can travel by bus between San Antonio, TX to Buffalo, NY with Greyhound, FlixBus for as low as $132 (€111). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
46h 35m
Cheapest FlixBus Price
$363 (€306)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
34h 10m
Cheapest Greyhound Price
$132 (€111)
Greyhound frequency
7 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between San Antonio, TX and Buffalo, NY
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from San Antonio, TX to Buffalo, NY, you can count on Greyhound, FlixBus for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Antonio, TX and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Buffalo, NY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Antonio, TX to Buffalo, NY for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from San Antonio, TX to Buffalo, NY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Buffalo, NY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Buffalo, NY:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Antonio, TX to Buffalo, NY. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from San Antonio, TX to Buffalo, NY with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from San Antonio, TX to Buffalo, NY with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from San Antonio, TX to Buffalo, NY with the following bus company: Greyhound, FlixBus.
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
Plan your visit to Buffalo, NY
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Buffalo, NY.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from San Antonio, TX to Buffalo, NY
Find answers to the most common questions about traveling from San Antonio, TX to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Buffalo, NY including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from San Antonio, TX to Buffalo, NY
Most San Antonio, TX to Buffalo, NY buses use the San Antonio, N St Mary's St (Greyhound) to Cheektowaga, BNIA Drway & BNIA Terminal station pair, with some services arriving at Buffalo, NFTA Metro Center. Use this guide to compare San Antonio, TX and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Antonio
Arrival bus stations in Buffalo
Which San Antonio, TX station do buses to Buffalo, NY leave from?
Buses from San Antonio, TX to Buffalo, NY leave from San Antonio, N St Mary's St (Greyhound). The station is 0 miles (1 km) from San Antonio, TX city centre at 500 N St Mary's St, San Antonio, TX 78205, USA.
San Antonio, N St Mary's St (Greyhound)500 N St Mary's St, San Antonio, TX 78205, USA
City-centre transport
Getting to San Antonio, N St Mary's St (Greyhound) from San Antonio city centre
TRUE
San Antonio, N St Mary's St (Greyhound) bus station facilities and services
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Tickets and information
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Parking, taxis and toilets
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl PkwyAvenue A & Pearl Pkwy, San Antonio, TX 78215, USA
City-centre transport
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
BusFlixBus 2230 · 11m · $2
10, 14, 214, 9 · 12m · $3 · every ~17 min
San Antonio, Avenue A / Pearl Pkwy bus station facilities and services
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Tickets and information
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Parking, taxis and toilets
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $8
24, 78 · 31m · $3 · every ~4 min
24, 78 · 46m · $3 · every ~4 min
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and San Antonio, TX
Most popular bus connections to Buffalo, NY
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
