San Diego, CA to Buffalo, NY bus with Greyhound

Wed, Feb 04
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1,000+ travel companies
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Travel Information

Compare train for San Diego, CA to Buffalo, NY

Omio recommends booking the flight as it is the most popular option from San Diego, CA to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from €302. For those with little time consider booking a flight which can get you there in 5h 36m. The ticket price range depends on the travel mode: a bus costs an average of €302, and a train costs an average of €451.

Distance: 2183 miles (3514 km)

Compare bus with

Bus
Most popular
Flight
Train

€302

Average price

Cheapest

€419

Average price

€451

Average price

64h 55m

Average total duration

64h 25m

Onboard

+

30m

Additional time*

8h 36m

Average total duration

Fastest

5h 36m

Onboard

+

3h 0m

Additional time*

64h 22m

Average total duration

63h 52m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets San Diego, CA to Buffalo, NY by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Feb 04
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Why should you book San Diego, CA to Buffalo, NY buses with Omio?

Greyhound operates all buses services from San Diego, CA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Buffalo, NY.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from San Diego, CA to Buffalo, NY.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Why book with Omio over Wanderu?

    Journey information

    Overview: Bus from San Diego, CA to Buffalo, NY

    USAUSA
    USAUSA
    Icon of bus

    Buses from San Diego, CA to Buffalo, NY run on average 8 times per day, taking around 64h 25m. Cheap bus tickets for this journey start at $379 (€302) if you book in advance.

    The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 71h 30m.

    Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
    Price information
    Distance
    2183 miles (3514 km)
    Average bus duration
    64h 25m
    Cheapest ticket price
    $379 (€302)
    Buses per day
    8
    Fastest bus
    71h 30m
    First bus
    00:55
    Last bus
    23:20
    Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
    Price information

    Bus providers: Greyhound from San Diego, CA to Buffalo, NYYou can travel by bus between San Diego, CA to Buffalo, NY with Greyhound for as low as $379 (€302). When you search for schedules and tickets, Omio will show you the best journey

    Greyhound

    About
    Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
    Luggage & cancellation policy
    Average Duration
    83h 40m
    Cheapest Price
    $245 (€195)
    Greyhound frequency
    10 a day
    Luggage included
    One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Additional luggage
    $15 per additional bag.
    Cancellation Policy
    You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
    Amenities on board the bus
    Wifi
    Food sold onboard
    Seat reservation
    Toilets
    USB plugs
    Accessibility
    Assistance; Priority seating; Wheelchair-accessible buses.
    Bikes
    Bikes are allowed.

    FAQs: Bus from San Diego, CA to Buffalo, NY

    Find answers to the most common questions about traveling from San Diego, CA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

    FAQs
    Cheap bus tickets from San Diego, CA to Buffalo, NY can start from as little as $379 (€302) when you book in advance. The average bus ticket price for San Diego, CA to Buffalo, NY is $379 (€302) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
    The average journey time by bus from San Diego, CA to Buffalo, NY is 71h 30m to travel the 2183 miles (3514 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
    The earliest bus from San Diego, CA to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
    The latest bus from San Diego, CA to Buffalo, NY leaves at 11:20 PM.
    There are 8 buses a day from San Diego, CA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
    When taking a bus from San Diego, CA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Diego, CA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
    A trip to Buffalo, NY from San Diego, CA is worth doing but not as a day trip with a journey time of 71h 30m each way. Check with Omio app the best way to travel.
    The cheapest month for a bus from San Diego, CA to Buffalo, NY is November.
    Yes, you can take a train between San Diego, CA and Buffalo, NY.
    Yes, there are bathrooms on board the bus from San Diego, CA to Buffalo, NY for bus company Greyhound.
    Yes, the following accessibility options are available when taking the bus from San Diego, CA to Buffalo, NY:
    • Greyhound
      • Assistance
      • Priority seating
      • Wheelchair-accessible buses.
    Whether you can cancel your bus ticket from San Diego, CA to Buffalo, NY depends on the bus companies:
    • Greyhound
      • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
    Yes, bikes are allowed on board the bus with bus company Greyhound.
    Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
    Yes, there is food available to purchase on board the bus from San Diego, CA to Buffalo, NY.
    Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Buffalo, NY:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Buffalo, NY:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from San Diego, CA to Buffalo, NY.
    You can reserve your seat on the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from San Diego, CA to Buffalo, NY

    San Diego
    Buffalo
    The major bus station for departures in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip from San Diego to Buffalo.
    San Diego, Congress Street (Old Town Park)
    information
    San Diego, San Ysidro Transit Center
    information
    San Diego, West Harbor Drive (The Headquarters at Seaport District)
    information

    More options for your journey from San Diego, CA to Buffalo, NY

    Here are some other resources that might have the information you need

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