- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
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Travel Information
Compare train, bus, and flight for San Diego, CA to Buffalo, NY
Omio recommends booking the train as it is the most popular option from San Diego, CA to Buffalo, NY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $421 For those with little time, consider booking a flight, which has an average total journey time of 8h 48m. Average ticket prices depend on the travel mode: a bus costs an average of $421, while a flight costs an average of $801.
Distance: 2183 miles (3514 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$421 Average price Cheapest | $442 Average price | $801 Average price | $520 Average price (fuel + tolls) |
62h 21m Average total duration 61h 51m Onboard + 30m Additional time* | 56h 59m Average total duration 56h 29m Onboard + 30m Additional time* | 8h 48m Average total duration Fastest 6h 48m Onboard + 2h 0m Additional time* | 37h 24m Average total duration (door-to-door) |
 Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Diego, CA to Buffalo, NY is a bus with an average price of $421.
This is compared to other travel options from San Diego, CA to Buffalo, NY:
A bus is $21 less than a train for this route with tickets for a train from San Diego, CA to Buffalo, NY costing on average $442.
A bus is $380 less than a flight for this route with tickets for a flight from San Diego, CA to Buffalo, NY costing on average $801.
The fastest way to travel from San Diego, CA to Buffalo, NY is by flight with an average journey time of 6h 48m.
Other travel options to Buffalo, NY take longer:
Train takes on average 56h 29m.
Bus takes on average 61h 51m.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Buffalo, NY including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from San Diego, CA to Buffalo, NY among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $421 compared to roughly $520 in fuel and tolls — a saving of about $100. The journey takes 61h 51m versus 37h 24m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
San Diego, CA to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:00AM | Arrival Time 10:40PM | Duration 87h40 | Departure days Tue | Cheapest price $757 |
Operator Greyhound | Departure Time 07:35AM | Arrival Time 08:00AM | Duration 69h25 | Departure days Thu | Cheapest price $270 |
Operator Greyhound | Departure Time 09:15AM | Arrival Time 06:30PM | Duration 78h15 | Departure days Thu | Cheapest price $280 |
Operator Greyhound | Departure Time 09:50AM | Arrival Time 06:30PM | Duration 77h40 | Departure days Thu | Cheapest price $271 |
Operator Greyhound | Departure Time 12:40PM | Arrival Time 08:00AM | Duration 64h20 | Departure days Thu | Cheapest price $247 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 04:40AM | Duration 84h30 | Departure days Thu | Cheapest price $247 |
Operator Greyhound | Departure Time 04:50PM | Arrival Time 12:00PM | Duration 67h10 | Departure days Fri | Cheapest price $263 |
Operator Greyhound | Departure Time 07:10PM | Arrival Time 08:25AM | Duration 82h15 | Departure days Thu | Cheapest price $257 |
Operator Greyhound Mexico | Departure Time 07:25PM | Arrival Time 10:40PM | Duration 75h15 | Departure days Tue | Cheapest price $769 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 04:45PM | Duration 66h00 | Departure days Thu | Cheapest price $257 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 08:45PM | Duration 72h35 | Departure days Wed | Cheapest price $287 |
Live departures
San Diego, CA to Buffalo, NY bus times
The table below shows live departures for San Diego, CA to Buffalo, NY buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:50 PM San Diego, CA | 67h10 | 12:00 PM Buffalo, NY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to Buffalo, NY by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Diego, CA to Buffalo, NY buses with Omio?
Greyhound operates all buses services from San Diego, CA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Buffalo, NY.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to Buffalo, NY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to Buffalo, NY.
Journey information
Overview: Bus from San Diego, CA to Buffalo, NY
USAUSA
Buses from San Diego, CA to Buffalo, NY run on average 4 times per day, taking around 61h 51m. Cheap bus tickets for this journey start at $365 if you book in advance.
The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 61h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 2183 miles (3514 km) |
Average bus duration 61h 51m |
Cheapest ticket price $365 |
Buses per day 4 |
Fastest bus 61h 15m |
First bus 12:55 AM |
Last bus 11:20 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Diego, CA to Buffalo, NYYou can travel by bus between San Diego, CA to Buffalo, NY with Greyhound for as low as $365. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
61h 15m
Cheapest Greyhound Price
$365
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
FAQs: Bus from San Diego, CA to Buffalo, NY
Find answers to the most common questions about traveling from San Diego, CA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Diego, CA to Buffalo, NY can start from as little as $365 when you book in advance. The average bus ticket price for San Diego, CA to Buffalo, NY is $421 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Buffalo, NY is 61h 15m to travel the 2183 miles (3514 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Buffalo, NY leaves at 11:20 PM.
There are 4 buses a day from San Diego, CA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Diego, CA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
A trip to Buffalo, NY from San Diego, CA is worth doing but not as a day trip with a journey time of 61h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Buffalo, NY is May.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Buffalo, NY including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from San Diego, CA to Buffalo, NY for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Buffalo, NY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from San Diego, CA to Buffalo, NY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Buffalo, NY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Buffalo, NY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Buffalo, NY.
You can reserve your seat on the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.
Since neither San Diego, CA nor Buffalo, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from San Diego, CA to Buffalo, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Diego, CA to Buffalo, NY
Most San Diego, CA to Buffalo, NY buses use the San Diego, Congress Street (Old Town Park) to Buffalo, NFTA Metro Center station pair, with some services arriving at Cheektowaga, BNIA Drway & BNIA Terminal. Use this guide to compare San Diego, CA and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Diego
Arrival bus stations in Buffalo
Which San Diego, CA station do buses to Buffalo, NY leave from?
Buses from San Diego, CA to Buffalo, NY leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USA
City-centre transport
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 20m · $1
83 · 26m · $6
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USA
City-centre transport
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 25m · $2
910 · 41m · $6
TramBlue · 41m · $17 · every ~14 min
Blue · 43m · $17 · every ~14 min
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USA
City-centre transport
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
TRUE
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Which Buffalo, NY station do buses from San Diego, CA arrive at?
Buses from San Diego, CA to Buffalo, NY most often arrive at Buffalo, NFTA Metro Center. Some services arrive at Cheektowaga, BNIA Drway & BNIA Terminal, so check your ticket before travel to confirm your Buffalo, NY arrival station.
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $7
24, 78 · 31m · $2 · every ~4 min
24, 78 · 46m · $2 · every ~4 min
More options for your journey from San Diego, CA to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and San Diego, CA
Most popular bus connections to Buffalo, NY
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