- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from San Diego, CA to Buffalo, NY
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- €619
- Average ticket price on Nov 03
- €624
- Fastest journey on Nov 03
- 3 d 3 h 15 m
- Average journey duration on Nov 03
- 3 d 9 h 28 m
- Buses on Nov 03
- 2
- Distance
- 3514 km
Cheap tickets
The best way to find a cheap bus ticket from San Diego, CA to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to Buffalo, NY will cost around €624 if you buy it on the day, but the cheapest tickets can be found for only €619.
Fast buses
It's difficult to get from San Diego, CA to Buffalo, NY without transferring at least 4 times.
7:00 AM 87h40 San Diego, CA 10:40 PM Buffalo, NY €619 1 One-way 4 transfers7:25 PM 75h15 San Diego, CA 10:40 PM Buffalo, NY €629 1 One-way 5 transfers
7:25 PM 75h15 San Diego, CA 10:40 PM Buffalo, NY €629 1 One-way 5 transfers7:00 AM 87h40 San Diego, CA 10:40 PM Buffalo, NY €619 1 One-way 4 transfers
Journey information
Overview: Bus from San Diego, CA to Buffalo, NY
USAUSA
Buses from San Diego, CA to Buffalo, NY run on average 4 times per day, taking around 61h 51m. Cheap bus tickets for this journey start at €299 if you book in advance.
The earliest bus runs at 00:55, the last at 23:20. The fastest bus covers the 2183 miles (3514 km) distance in 61h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance2183 miles (3514 km)
- Average bus duration61h 51m
- Cheapest ticket price€299
- Buses per day4
- Fastest bus61h 15m
- First bus12:55 AM
- Last bus11:20 PM
- Cheapest MonthMay
- Cheapest DayThu
- High SeasonJan - Mar
- Low SeasonJul - Sep
- Best time to book28 days
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your San Diego, CA to Buffalo, NY trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Diego, CA to Buffalo, NY.
Cheap bus tickets from San Diego, CA to Buffalo, NY can start from as little as €299 when you book in advance. The average bus ticket price for San Diego, CA to Buffalo, NY is €345 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from San Diego, CA to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Buffalo, NY leaves at 11:20 PM.
There are 4 buses a day from San Diego, CA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
San Diego, CA to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:00AM | Arrival Time 10:40PM | Duration 87h40 | Departure days Tue, Thu | Cheapest price €619 |
Operator Greyhound | Departure Time 04:50PM | Arrival Time 12:00PM | Duration 67h10 | Departure days Fri | Cheapest price €216 |
Operator Greyhound Mexico | Departure Time 07:25PM | Arrival Time 10:40PM | Duration 75h15 | Departure days Tue, Thu | Cheapest price €629 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 08:45PM | Duration 72h35 | Departure days Wed | Cheapest price €235 |
Why should you book San Diego, CA to Buffalo, NY buses with Omio?
Greyhound operates all buses services from San Diego, CA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Buffalo, NY.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to Buffalo, NY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to Buffalo, NY.
Bus companies
Bus companies from San Diego, CA to Buffalo, NY
Buses from San Diego, CA to Buffalo, NY with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
61h 15m
Cheapest Greyhound Price
€299
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between San Diego, CA and Buffalo, NY
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from San Diego, CA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Diego, CA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Buffalo, NY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to Buffalo, NY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from San Diego, CA to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Buffalo, NY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Buffalo, NY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Buffalo, NY.
You can reserve your seat on the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
Plan your visit to Buffalo, NY
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Buffalo, NY.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from San Diego, CA to Buffalo, NY
Find answers to the most common questions about traveling from San Diego, CA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Buffalo, NY including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from San Diego, CA to Buffalo, NY
Most San Diego, CA to Buffalo, NY buses use the San Diego, Congress Street (Old Town Park) to Cheektowaga, BNIA Drway & BNIA Terminal station pair, with some services arriving at Buffalo, NFTA Metro Center. Use this guide to compare San Diego, CA and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Diego
Arrival bus stations in Buffalo
Which San Diego, CA station do buses to Buffalo, NY leave from?
Buses from San Diego, CA to Buffalo, NY leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USA
City-centre transport
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 20m · €1
83 · 26m · €5
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USA
City-centre transport
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 25m · €2
910 · 41m · €5
TramBlue · 41m · €14 · every ~14 min
Blue · 43m · €14 · every ~14 min
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USA
City-centre transport
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
TRUE
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · €6
24, 78 · 31m · €2 · every ~4 min
24, 78 · 46m · €2 · every ~4 min
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Most popular bus connections from San Diego, CA
Most popular buses to and from Buffalo, NY and San Diego, CA
Most popular bus connections to Buffalo, NY
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
