- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
The best way to find a cheap bus ticket from Milwaukee, WI to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Buffalo, NY will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $157.
It's difficult to get from Milwaukee, WI to Buffalo, NY without transferring at least 2 times.

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Buses from Milwaukee, WI to Buffalo, NY run on average 2 times per day, taking around 12h 51m. Cheap bus tickets for this journey start at $57 if you book in advance.
The earliest bus runs at 03:20, the last at 22:45. The fastest bus covers the 456 miles (734 km) distance in 12h 35m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Milwaukee, WI to Buffalo, NY.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 06:30AM | Arrival Time 10:40PM | Duration 16h10 | Departure days Wed, Fri | Cheapest price $157 |
Operator Flixbus USA | Departure Time 03:20PM | Arrival Time 04:45PM | Duration 25h25 | Departure days Wed, Fri | Cheapest price $166 |
Operator Greyhound | Departure Time 03:20PM | Arrival Time 08:00AM | Duration 15h40 | Departure days Mon, Sat, Sun | Cheapest price $81 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 08:00AM | Duration 15h20 | Departure days Mon, Sat, Sun | Cheapest price $81 |
Operator Greyhound | Departure Time 08:40PM | Arrival Time 12:00PM | Duration 15h20 | Departure days Tue | Cheapest price $153 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 09:45PM | Duration 24h05 | Departure days Thu | Cheapest price $157 |
The table below shows live departures for Milwaukee, WI to Buffalo, NY buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:40 PM Milwaukee, WI | 15h20 | 12:00 PM Buffalo, NY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Milwaukee, WI to Buffalo, NY with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Buffalo, NY.
Find answers to the most common questions about traveling from Milwaukee, WI to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

Most Milwaukee, WI to Buffalo, NY buses use the Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) to Buffalo, NFTA Metro Center station pair. Use this guide to compare Milwaukee, WI and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) is 10 km from Milwaukee city centre. Public transport options include:
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food options are available within the airport terminal.
Wi-Fi is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). ATMs are aTMs are available in the airport terminal.
Ticket office support is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop).
Available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): The station is accessible with facilities for disabled passengers.
Milwaukee, Intermodal Station is 1 km from Milwaukee city centre. Public transport options include:
Milwaukee, Intermodal Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafe and vending machines available.
Wi-Fi available in waiting areas. ATMs are aTM machines available inside the station.
Ticket office support is available at Milwaukee, Intermodal Station.
Available at Milwaukee, Intermodal Station: Parking, Taxis, WC.
Accessibility facilities are available at Milwaukee, Intermodal Station: ADA compliant with elevators and ramps.
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Ticket office support is available at Buffalo, NFTA Metro Center.
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Check bus stations information for Milwaukee, WI and Buffalo, NY, including where buses depart and arrive on this route.