- Must visit
Buffalo AKG Art Museum
Buffalo’s flagship art museum, known for its strong modern and contemporary collection and major architectural expansion. A top choice for art lovers.
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The cheapest and fastest buses from San Francisco, CA to Buffalo, NY
Showing times and prices for Jun 20
Cheapest price
$272
Average price
$307
Fastest journey
2 d 15 h 30 m
Average duration
3 d 7 h
Buses per day
4
Distance
3693 km
Cheap tickets
The best way to find a cheap bus ticket from San Francisco, CA to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Buffalo, NY will cost around $307 if you buy it on the day, but the cheapest tickets can be found for only $272.
Fast buses
It's difficult to get from San Francisco, CA to Buffalo, NY without transferring at least 3 times.
· · · 1:30 PM63h30San Francisco, Transit Center Bay 298:00 AMBuffalo, NFTA Metro Center$2721One-way4 transfers- · · · 12:40 PM85h00San Francisco, Transit Center Bay 294:40 AMCheektowaga, BNIA Drway & BNIA Terminal$2821One-way5 transfers
- · · · 10:30 PM78h30San Francisco, Transit Center Bay 298:00 AMBuffalo, NFTA Metro Center$3241One-way4 transfers
- · · +
FlixBus10:30 PM89h00San Francisco, Transit Center Bay 296:30 PMCheektowaga, BNIA Drway & BNIA Terminal$3521One-way3 transfers
- · · · 1:30 PM63h30San Francisco, Transit Center Bay 298:00 AMBuffalo, NFTA Metro Center$2721One-way4 transfers
- · · · 10:30 PM78h30San Francisco, Transit Center Bay 298:00 AMBuffalo, NFTA Metro Center$3241One-way4 transfers
- · · · 12:40 PM85h00San Francisco, Transit Center Bay 294:40 AMCheektowaga, BNIA Drway & BNIA Terminal$2821One-way5 transfers
- · · +FlixBus10:30 PM89h00San Francisco, Transit Center Bay 296:30 PMCheektowaga, BNIA Drway & BNIA Terminal$3521One-way3 transfers
Travel Information
Compare bus, train, and flight for San Francisco, CA to Buffalo, NY
Omio recommends booking the train as it is the most popular option from San Francisco, CA to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $245. For those with little time consider booking a flight which can get you there in 8h 8m. The ticket price range depends on the travel mode: a bus costs an average of $245, and a train costs an average of $658.
Distance: 2294 miles (3693 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$262 Average price Cheapest | $659 Average price | $348 Average price |
71h 25m Average total duration 70h 55m Onboard + 30m Additional time* | 63h 7m Average total duration 62h 37m Onboard + 30m Additional time* | 11h 8m Average total duration Fastest 8h 8m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Francisco, CA to Buffalo, NY is a bus with an average price of $262 (€214).
This is compared to other travel options from San Francisco, CA to Buffalo, NY:
A bus is $86 (€71) less than a flight for this route with tickets for a flight from San Francisco, CA to Buffalo, NY costing on average $348 (€285).
A bus is $397 (€326) less than a train for this route with tickets for a train from San Francisco, CA to Buffalo, NY costing on average $659 (€540).
The fastest way to travel from San Francisco, CA to Buffalo, NY is by flight with an average journey time of 8h 8m.
Other travel options to Buffalo, NY take longer:
Train takes on average 62h 37m.
Bus takes on average 70h 55m.
It's helpful to compare your options as there are 3 ways to travel between San Francisco, CA and Buffalo, NY including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from San Francisco, CA to Buffalo, NY among Omio's users.
San Francisco, CA to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:40AM | Arrival Time 12:00PM | Duration 78h20 | Departure days Thu | Cheapest price $279 |
Operator Greyhound | Departure Time 12:40PM | Arrival Time 04:40AM | Duration 85h00 | Departure days Sat | Cheapest price $282 |
Operator Greyhound USA | Departure Time 01:30PM | Arrival Time 04:45PM | Duration 75h15 | Departure days Tue, Thu, Fri, Sat | Cheapest price $272 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 08:00AM | Duration 78h30 | Departure days Sat | Cheapest price $324 |
Operator Greyhound USA | Departure Time 10:40PM | Arrival Time 12:45PM | Duration 86h05 | Departure days Tue, Thu | Cheapest price $884 |
Compare prices and tickets San Francisco, CA to Buffalo, NY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Francisco, CA to Buffalo, NY buses with Omio?
Greyhound operates all buses services from San Francisco, CA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Francisco, CA to Buffalo, NY.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from San Francisco, CA to Buffalo, NY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from San Francisco, CA to Buffalo, NY.
Journey information
Overview: Bus from San Francisco, CA to Buffalo, NY
USAUSA
Buses from San Francisco, CA to Buffalo, NY run on average 6 times per day, taking around 70h 55m. Cheap bus tickets for this journey start at $245 (€200) but you can travel from only $243 (€199) by flight.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 2294 miles (3693 km) distance in 63h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $243 (€199)
Distance 2294 miles (3693 km) |
Average bus duration 70h 55m |
Cheapest ticket price $245 (€200) |
Buses per day 6 |
Fastest bus 63h 30m |
First bus 12:55 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 2 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $243 (€199)
Bus providers: Greyhound from San Francisco, CA to Buffalo, NYYou can travel by bus between San Francisco, CA to Buffalo, NY with Greyhound for as low as $243 (€199). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
63h 30m
Cheapest Price
$245 (€200)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Buffalo
Things to do in Buffalo
Discover the best of Buffalo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo trip today.
- Must visit
Frank Lloyd Wright’s Martin House
An important architectural museum complex and one of Frank Lloyd Wright’s masterpieces, offering deep insight into Prairie School design.
- Recommended
The Buffalo History Museum
A regional history museum in a landmark 1901 Pan-American Exposition building, with exhibits on Buffalo, Erie County, and Western New York.
- Must visit
Canalside
Buffalo’s revitalized waterfront district, popular for boardwalk walks, harbor views, events, and social-media-friendly public spaces.
- Must visit
Delaware Park
A major Frederick Law Olmsted-designed park with scenic roads, the lake, gardens, and cultural institutions nearby. Ideal for walking and relaxing.
- Recommended
Elmwood Village
One of Buffalo’s best-known neighborhoods for strolling, lined with historic homes, local shops, and a lively but relaxed urban atmosphere.
Buffalo Wings
Crispy chicken wings tossed in a buttery cayenne hot sauce, traditionally served with celery and blue cheese. Buffalo’s signature dish originated here and is the city’s must-try food.
Beef on Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway seeds, usually served with horseradish and au jus. It is a classic Western New York sandwich strongly associated with BU
- Vegetarian
- Gluten-free
Sponge Candy
A regional confection made from airy honeycomb toffee coated in chocolate. Buffalo is especially known for it, and local chocolatiers have made it a beloved traditional sweet.
The Left Bank
A long-running bistro on the West Side with a more refined atmosphere, known for consistently good American and European-inspired dishes. A solid option beyond tavern fare.
Schwabl's
A classic Buffalo restaurant renowned for beef on weck, old-school service, and a traditional dining room atmosphere. One of the best-known places to try this regional specialty.
Gabriel's Gate
A beloved neighborhood tavern in a historic building, known for wings, hearty pub food, and a warm local atmosphere. Popular with both residents and visitors.
United States Dollar
Moderate by U.S. standards. Hotels vary by season, while casual dining, coffee, and local transport are fairly affordable.
Average meal costs
- Budget
- USD 10-18 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a regular coffee or latte.
Tipping culture
Tip 18-20% at restaurants if service is not included; 15-20% for taxis and rideshares. USD 1-2 per drink at bars, USD 1-2 per bag for hotel porters, and a few dollars daily for housekeeping.
FAQs: Bus from San Francisco, CA to Buffalo, NY
Find answers to the most common questions about traveling from San Francisco, CA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Francisco, CA to Buffalo, NY can start from as little as $245 (€200) when you book in advance. The average bus ticket price for San Francisco, CA to Buffalo, NY is $262 (€214) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Francisco, CA to Buffalo, NY is 63h 30m to travel the 2294 miles (3693 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Francisco, CA to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Francisco, CA to Buffalo, NY leaves at 11:55 PM.
There are 6 buses a day from San Francisco, CA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Francisco, CA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Francisco, CA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
A trip to Buffalo, NY from San Francisco, CA is worth doing but not as a day trip with a journey time of 63h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Francisco, CA to Buffalo, NY is October.
It's helpful to compare your options as there are 3 ways to travel between San Francisco, CA and Buffalo, NY including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from San Francisco, CA to Buffalo, NY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Francisco, CA to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from San Francisco, CA to Buffalo, NY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Francisco, CA to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from San Francisco, CA to Buffalo, NY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Francisco, CA to Buffalo, NY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Francisco, CA to Buffalo, NY.
You can reserve your seat on the bus from San Francisco, CA to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Francisco, CA to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Francisco, CA to Buffalo, NY with the following bus company: Greyhound.
Since neither San Francisco, CA nor Buffalo, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from San Francisco, CA to Buffalo, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Francisco, CA to Buffalo, NY
San Francisco
Buffalo
The major bus station for departures in San Francisco is San Francisco, Transit Center Bay 29. Find all the information you need to know about services, amenities and connections at San Francisco, Transit Center Bay 29 for your trip from San Francisco to Buffalo.
San Francisco, Transit Center Bay 29
information
San Francisco, Townsend Street / 5th Street
information
The major bus station for arrivals in Buffalo is Cheektowaga, BNIA Drway & BNIA Terminal. Find all the information you need to know about services, amenities and connections at Cheektowaga, BNIA Drway & BNIA Terminal for your trip to Buffalo from San Francisco.
Cheektowaga, BNIA Drway & BNIA Terminal
information
Buffalo, NFTA Metro Center
information
Most popular bus connections from San Francisco, CA
More options for your journey from San Francisco, CA to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and San Francisco, CA
Most popular bus connections to Buffalo, NY
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