- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
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The cheapest and fastest buses from San Francisco, CA to Buffalo, NY
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- $198
- Average ticket price on Nov 03
- $224
- Fastest journey on Nov 03
- 2 d 15 h 50 m
- Average journey duration on Nov 03
- 3 d 5 h 8 m
- Buses on Nov 03
- 9
- Distance
- 3693 km
Cheap tickets
The best way to find a cheap bus ticket from San Francisco, CA to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Buffalo, NY will cost around $224 if you buy it on the day, but the cheapest tickets can be found for only $198.
Fast buses
It's difficult to get from San Francisco, CA to Buffalo, NY without transferring at least 3 times.
· · · 1:10 PM 63h50 San Francisco, Transit Center Bay 29 8:00 AM Buffalo, NFTA Metro Center $198 1 One-way 4 transfers
FlixBus+ · · 8:55 AM 68h05 San Francisco, Townsend Street / 5th Street, CA 8:00 AM Buffalo, NFTA Metro Center $201 1 One-way 5 transfers- FlixBus+ · +FlixBus
1:00 AM 86h30 San Francisco, Townsend Street / 5th Street, CA 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal $210 1 One-way 3 transfers - FlixBus+ · ·
8:55 AM 88h45 San Francisco, Townsend Street / 5th Street, CA 4:40 AM Cheektowaga, BNIA Drway & BNIA Terminal $213 1 One-way 5 transfers - · · ·
6:30 AM 103h10 San Francisco, Transit Center Bay 29 4:40 PM Cheektowaga, BNIA Drway & BNIA Terminal $218 1 One-way 5 transfers
- · · ·
1:10 PM 63h50 San Francisco, Transit Center Bay 29 8:00 AM Buffalo, NFTA Metro Center $198 1 One-way 4 transfers - FlixBus+ · ·
8:55 AM 68h05 San Francisco, Townsend Street / 5th Street, CA 8:00 AM Buffalo, NFTA Metro Center $201 1 One-way 5 transfers - · · ·
10:30 PM 78h30 San Francisco, Transit Center Bay 29 8:00 AM Buffalo, NFTA Metro Center $240 1 One-way 4 transfers - FlixBus+ · +FlixBus
1:00 AM 86h30 San Francisco, Townsend Street / 5th Street, CA 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal $210 1 One-way 3 transfers - FlixBus+ · ·
8:55 AM 88h45 San Francisco, Townsend Street / 5th Street, CA 4:40 AM Cheektowaga, BNIA Drway & BNIA Terminal $213 1 One-way 5 transfers
Journey information
Overview: Bus from San Francisco, CA to Buffalo, NY
USAUSA
Buses from San Francisco, CA to Buffalo, NY run on average 3 times per day, taking around 62h 10m. Cheap bus tickets for this journey start at $116 if you book in advance.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 2294 miles (3693 km) distance in 58h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 2294 miles (3693 km) |
Average bus duration 62h 10m |
Cheapest ticket price $116 |
Buses per day 3 |
Fastest bus 58h 5m |
First bus 12:55 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 2 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your San Francisco, CA to Buffalo, NY trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Francisco, CA to Buffalo, NY.
Cheap bus tickets from San Francisco, CA to Buffalo, NY can start from as little as $116 when you book in advance. The average bus ticket price for San Francisco, CA to Buffalo, NY is $196 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from San Francisco, CA to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Francisco, CA to Buffalo, NY leaves at 11:55 PM.
There are 3 buses a day from San Francisco, CA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
San Francisco, CA to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 06:30PM | Duration 86h30 | Departure days Everyday | Cheapest price $175 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 04:40PM | Duration 103h10 | Departure days Tue, Wed, Sun | Cheapest price $190 |
Operator Greyhound | Departure Time 08:55AM | Arrival Time 04:40AM | Duration 88h45 | Departure days Everyday | Cheapest price $164 |
Operator Greyhound | Departure Time 12:40PM | Arrival Time 04:40AM | Duration 85h00 | Departure days Mon, Thu, Sat | Cheapest price $169 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 08:00AM | Duration 63h50 | Departure days Everyday | Cheapest price $162 |
Operator Greyhound | Departure Time 06:05PM | Arrival Time 06:30PM | Duration 93h25 | Departure days Mon, Tue, Wed, Sun | Cheapest price $177 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 06:30PM | Duration 89h00 | Departure days Everyday | Cheapest price $190 |
Live departures
San Francisco, CA to Buffalo, NY bus times
The table below shows live departures for San Francisco, CA to Buffalo, NY buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ · +FlixBus | 1:00 AM San Francisco, Townsend Street / 5th Street, CA | 86h30 | 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal | 3 transfers | |
| FlixBus+ · · | 8:55 AM San Francisco, Townsend Street / 5th Street, CA | 88h45 | 4:40 AM Cheektowaga, BNIA Drway & BNIA Terminal | 5 transfers | |
| FlixBus+ · · | 8:55 AM San Francisco, Townsend Street / 5th Street, CA | 68h05 | 8:00 AM Buffalo, NFTA Metro Center | 5 transfers | |
| · · · | 12:40 PM San Francisco, Transit Center Bay 29 | 85h00 | 4:40 AM Cheektowaga, BNIA Drway & BNIA Terminal | 5 transfers | |
| · · · | 1:10 PM San Francisco, Transit Center Bay 29 | 63h50 | 8:00 AM Buffalo, NFTA Metro Center | 4 transfers | |
| FlixBus+ · · | 6:05 PM San Francisco, Townsend Street / 5th Street, CA | 93h45 | 6:50 PM Buffalo, NFTA Metro Center | 5 transfers | |
| FlixBus+ · · | 6:05 PM San Francisco, Townsend Street / 5th Street, CA | 93h25 | 6:30 PM Cheektowaga, BNIA Drway & BNIA Terminal | 5 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book San Francisco, CA to Buffalo, NY buses with Omio?
Greyhound operates all buses services from San Francisco, CA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Francisco, CA to Buffalo, NY.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from San Francisco, CA to Buffalo, NY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from San Francisco, CA to Buffalo, NY.
Bus providers: Greyhound from San Francisco, CA to Buffalo, NYYou can travel by bus between San Francisco, CA to Buffalo, NY with Greyhound for as low as $116. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
58h 5m
Cheapest Greyhound Price
$116
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between San Francisco, CA and Buffalo, NY
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from San Francisco, CA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Francisco, CA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from San Francisco, CA to Buffalo, NY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Francisco, CA to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from San Francisco, CA to Buffalo, NY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from San Francisco, CA to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from San Francisco, CA to Buffalo, NY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Francisco, CA to Buffalo, NY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Francisco, CA to Buffalo, NY.
You can reserve your seat on the bus from San Francisco, CA to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Francisco, CA to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Francisco, CA to Buffalo, NY with the following bus company: Greyhound.
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
Plan your visit to Buffalo, NY
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Buffalo, NY.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from San Francisco, CA to Buffalo, NY
Find answers to the most common questions about traveling from San Francisco, CA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between San Francisco, CA and Buffalo, NY including taking a bus, flight, and train.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from San Francisco, CA to Buffalo, NY
Most San Francisco, CA to Buffalo, NY buses use the San Francisco, Townsend Street / 5th Street to Cheektowaga, BNIA Drway & BNIA Terminal station pair, with some services arriving at Buffalo, NFTA Metro Center. Use this guide to compare San Francisco, CA and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Francisco
Arrival bus stations in Buffalo
San Francisco, Townsend Street / 5th StreetSan Francisco Bus Station,401 Townsend St,94107
City-centre transport
Getting to San Francisco, Townsend Street / 5th Street from San Francisco city centre
BusEast, West · 20m · every ~4 min
Nbus, Nowl · 24m · $3 · every ~2 min
TramN · 23m · $3 · every ~11 min
San Francisco, Transit Center Bay 29Transit Center Bay 29, San Francisco, CA 94105, USA
City-centre transport
Getting to San Francisco, Transit Center Bay 29 from San Francisco city centre
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
Bus397 · 8m · $3
14, 14R · 13m · $3 · every ~30 min
101, 120 · 14m · $6 · every ~9 min
7 · 21m · $3 · every ~10 min
SubwayYellow-N, Green-N, Red-N, Blue-N · 10m · $3 · every ~27 min
San Francisco, Transit Center Bay 29 bus station facilities and services
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Tickets and information
Ticket office support is available at San Francisco, Transit Center Bay 29.
Parking, taxis and toilets
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $8
24, 78 · 31m · $3 · every ~4 min
24, 78 · 46m · $3 · every ~4 min
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
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Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Most popular bus connections from San Francisco, CA
More options for your journey from San Francisco, CA to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and San Francisco, CA
Most popular bus connections to Buffalo, NY
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