- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Flights from Baltimore, MD to Greenville, SC depart on average 19 times per day, taking around 4h 6m. Cheap flight tickets for this journey start at $197 (€161) but you can travel from only $82 (€67) by bus.
The earliest flight runs at 05:00, the last at 20:21. The fastest flight covers the 441 miles (711 km) distance in 3h 38m. November is the cheapest month to fly.
Distance 441 miles (711 km) |
Average flight duration 4h 6m |
Cheapest ticket price $197 (€161) |
Flights per day 19 |
Fastest flight 3h 38m |
First flight 5:00 AM |
Last flight 8:21 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Cheapest price
$214
Average price
$248
Fastest journey
3 h 38 m
Average duration
4 h 17 m
Flights per day
3
Distance
711 km
The best way to find a cheap flight ticket from Baltimore, MD to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Baltimore, MD to Greenville, SC will cost around $248 if you buy it on the day, but the cheapest tickets can be found for only $214.
Of the 3 flights that leave Baltimore, MD for Greenville, SC onSat, Jun 27, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 27 the direct flights cover the 711 km distance in an average of 4 h 17 m but if you time it right, some flights will get you there in just 3 h 38 m .
On Sat, Jun 27 the longest flights will take 5 h 14 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Baltimore, MD to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $82. For those with little time consider booking a flight which can get you there in 4h 6m. The ticket price range depends on the travel mode: a bus costs an average of $82, and a flight costs an average of $197.
Distance: 441 miles (711 km)
| Flight | Most popular Bus | Train | Driving |
|---|---|---|---|
$242 Average price | $93 Average price Cheapest | $196 Average price | $104 Average price (fuel + tolls) |
7h 6m Average total duration Fastest 4h 6m Onboard + 3h 0m Additional time* | 13h 9m Average total duration 12h 39m Onboard + 30m Additional time* | 12h 50m Average total duration 12h 20m Onboard + 30m Additional time* | 8h 13m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Baltimore, MD to Greenville, SC:
A bus is $103 (€84) less than a train for this route with tickets for a train from Baltimore, MD to Greenville, SC costing on average $196 (€160).
A bus is $149 (€122) less than a flight for this route with tickets for a flight from Baltimore, MD to Greenville, SC costing on average $242 (€198).
Other travel options to Greenville, SC take longer:
Train takes on average 12h 20m.
Bus takes on average 12h 39m.
The table below shows live departures for Baltimore, MD to Greenville, SC flights for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:54 AM Baltimore, MD | 4h00 | 4:54 AM Greenville, SC | 0 transfersDirect | |
![]() | 9:05 AM Baltimore, MD | 5h14 | 2:19 PM Greenville, SC | 0 transfersDirect | |
![]() | 10:00 AM Baltimore, MD | 3h38 | 1:38 PM Greenville, SC | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Baltimore, MD to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

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