- Must visit
Vatican Museums
A vast complex of papal collections including classical sculpture, Renaissance masterpieces, the Raphael Rooms, and access to the Sistine Chapel. One of Rome’s most important art visits and often best
Cheapest price
$20
Average price
$33
Fastest journey
4 h 35 m
Average duration
5 h 1 m
Buses per day
10
Distance
265 km
The best way to find a cheap bus ticket from Pisa to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Rome will cost around $33 if you buy it on the day, but the cheapest tickets can be found for only $20.
Of the 10 buses that leave Pisa for Rome on Mon, May 25, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct buses cover the 265 km distance in an average of 5 h 1 m but if you time it right, some buses will get you there in just 4 h 35 m .
On Mon, May 25 the slowest buses will take 5 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
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FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Pisa to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $16. For those with little time consider booking a train which can get you there in 3h 37m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $16, and a train costs an average of $26.
Distance: 164 miles (265 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$26 Average price Cheapest | $34 Average price | $84 Average price (fuel + tolls) |
5h 2m Average total duration 4h 32m Onboard + 30m Additional time* | 4h 7m Average total duration Fastest 3h 37m Onboard + 30m Additional time* | 3h 50m Average total duration (door-to-door) |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Rome:
A bus is $8 (€6) less than a train for this route with tickets for a train from Pisa to Rome costing on average $34 (€28).
Other travel options to Rome take longer:
Train takes on average 3h 37m.
Bus takes on average 4h 32m.
Tickets start at around $26 (€21) compared to roughly $84 (€68) in fuel and tolls — a saving of about $58 (€47). The journey takes 4h 32m versus 3h 50m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Marino Autolinee, BlaBlaCar, Itabus, AutoLinee Moretti.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 05:55AM | Duration 5h30 | Departure days Mon, Tue, Fri, Sat | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 04:00AM | Arrival Time 08:00AM | Duration 4h00 | Departure days Sat | Cheapest price $31 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 11:25AM | Duration 6h40 | Departure days Tue, Sat, Sun | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 05:00AM | Arrival Time 08:40AM | Duration 3h40 | Departure days Wed | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 09:30AM | Duration 3h30 | Departure days Tue, Thu | Cheapest price $33 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 10:50AM | Duration 4h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $17 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 01:20PM | Duration 6h05 | Departure days Everyday | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 07:40AM | Arrival Time 11:40AM | Duration 4h00 | Departure days Sat | Cheapest price $41 |
Operator Marino Autolinee | Departure Time 08:20AM | Arrival Time 02:20PM | Duration 6h00 | Departure days Everyday | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 01:40PM | Duration 5h10 | Departure days Sat | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 01:20PM | Duration 4h20 | Departure days Sun | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 09:20AM | Arrival Time 01:00PM | Duration 3h40 | Departure days Mon, Thu | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 01:50PM | Duration 4h20 | Departure days Mon, Tue | Cheapest price $33 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 04:05PM | Duration 6h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $43 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 02:20PM | Duration 4h20 | Departure days Wed, Thu, Sun | Cheapest price $20 |
Operator BlaBlaCar | Departure Time 10:10AM | Arrival Time 01:40PM | Duration 3h30 | Departure days Tue | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 02:00PM | Duration 3h30 | Departure days Sun | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 03:50PM | Duration 4h20 | Departure days Mon, Sat | Cheapest price $29 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 06:05PM | Duration 6h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $30 |
Operator BlaBlaCar | Departure Time 12:40PM | Arrival Time 04:40PM | Duration 4h00 | Departure days Mon, Fri, Sat | Cheapest price $26 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 06:35PM | Duration 5h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 06:00PM | Duration 4h00 | Departure days Wed | Cheapest price $38 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 06:20PM | Duration 3h50 | Departure days Fri | Cheapest price $34 |
Operator BlaBlaCar | Departure Time 03:40PM | Arrival Time 07:50PM | Duration 4h10 | Departure days Tue, Fri | Cheapest price $33 |
Operator BlaBlaCar | Departure Time 03:50PM | Arrival Time 07:30PM | Duration 3h40 | Departure days Fri | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 04:30PM | Arrival Time 08:10PM | Duration 3h40 | Departure days Thu, Sun | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 04:50PM | Arrival Time 08:30PM | Duration 3h40 | Departure days Tue | Cheapest price $34 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 11:00PM | Duration 5h50 | Departure days Tue, Wed | Cheapest price $29 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 10:35PM | Duration 5h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $20 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 09:40PM | Duration 4h10 | Departure days Wed | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 07:00PM | Arrival Time 11:50PM | Duration 4h50 | Departure days Mon | Cheapest price $21 |
Operator Busitalia | Departure Time 07:45PM | Arrival Time 11:59PM | Duration 4h14 | Departure days Tue, Fri, Sun | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 08:00PM | Arrival Time 12:50AM | Duration 4h50 | Departure days Thu, Fri | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 09:00PM | Arrival Time 01:20AM | Duration 4h20 | Departure days Wed | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 09:20PM | Arrival Time 01:50AM | Duration 4h30 | Departure days Tue | Cheapest price $44 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 02:35AM | Duration 4h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $22 |
The table below shows live departures for Pisa to Rome buses for today, Sunday, May 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 4:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h15 | 10:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 6:05 AM Pisa, Aeroporto Parcheggio Aurelia | 4h45 | 10:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h05 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h00 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h25 | 4:05 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 12:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h05 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 12:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h25 | 5:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h10 | 6:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h10 | 10:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
![]() | 7:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 4h14 | 11:59 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 4h35 | 2:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Monday, May 25 | |||||
FlixBus | 12:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h30 | 5:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pisa to Rome run on average 10 times per day, taking around 4h 32m. Cheap bus tickets for this journey start at $16 (€13) if you book in advance.
There are 8 buses per day. The earliest bus runs at 00:01, the last at 23:52. The fastest bus covers the 164 miles (265 km) distance in 4h 14m.
Distance 164 miles (265 km) |
Average bus duration 4h 32m |
Cheapest ticket price $16 (€13) |
Buses per day 10 |
Direct buses 8 |
Fastest bus 4h 14m |
First bus 12:01 AM |
Last bus 11:52 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 5 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
A vast complex of papal collections including classical sculpture, Renaissance masterpieces, the Raphael Rooms, and access to the Sistine Chapel. One of Rome’s most important art visits and often best
A superb villa museum with Bernini sculptures and paintings by Caravaggio, Raphael, and Titian. Timed entry is limited, making advance booking especially important.
The world’s oldest public museums, displaying Roman bronzes, ancient inscriptions, imperial sculpture, and excellent views over the Roman Forum from Capitoline Hill.
A grand baroque square with Bernini’s Fountain of the Four Rivers, elegant facades, and constant street life. One of Rome’s classic strolling areas.
A lively neighborhood of narrow lanes, ivy-covered buildings, and popular evening atmosphere. Very popular for wandering and photography, especially after sunset.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti. A classic meeting point and one of the city’s most photographed urban scenes.
A classic Roman pasta made with pecorino romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta with guanciale, egg yolk, pecorino romano, and black pepper. It is a defining dish of Rome and is traditionally made without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino romano, usually served with bucatini. It is a cornerstone of Roman trattoria cooking.
Rome’s best-known luxury dining destination, offering fine dining, panoramic views, and an acclaimed tasting-menu experience by Heinz Beck.
A historic restaurant near the Pantheon celebrated for careful Roman cooking, including gricia, oxtail, and seasonal specialties, in a polished traditional space.
A famous central Rome dining room and delicatessen known for Roman pasta, cured meats, cheeses, and an exceptional wine list in a lively upscale setting.
Moderate by Western Europe standards: sights and central hotels cost more, while casual dining and transit stay reasonable.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-2 at cafes, 5-10% for great restaurant service, and round up taxis.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola, Rome -> Roma Termini, Rome
Florence and Fiumicino sit approximately 146 miles (236 km) apart, with the route offering roughly 74 services per day on weekdays, 72 on Saturdays, and 69 on Sundays. The frequency offers over 500 operations per week, meaning you can get about three to six trains from Florence to Fiumicino hourly. These services typically take anywhere between around 1h 56min and 5h 19min to complete the journey.
You can get the first train from Florence to Fiumicino at around 5:45 a.m. from Monday to Saturday and holidays. The Sunday schedule begins at approximately 6:40 a.m. Besides these, you can find the final service departing every day at about 8:48 p.m. The non_stop trains operate twice each day, commencing at around 8:26 a.m. and 11:48 a.m. All the other services except one involve one change along the route. The ride departing at roughly 5:14 p.m. features two transfer points and presents the voyage with the longest duration.
Generally, trains from Florence to Fiumicino can take about 1 h 56 min to 5 h 19 min, depending on the transfer requirements. This journey via train from Florence to Fiumicino incorporates two non_stop services on weekdays. The earlier departure provides the shortest overall duration of roughly 1 h 56 min. All remaining services feature a change on the course, taking around 2 h 06 min to 5 h 19 min to complete the comfortable voyage.



Departure train station: A trip to Fiumicino from Florence via train commences at Florence Santa Maria Novella, Florence Rifredi, or Florence Campo di Marte. Many services utilize Florence Santa Maria Novella as their departure point, located roughly 3 miles (4.8 km) from central Florence. It is accessible within approximately 29min via bus routes 14, 12, or 366A, a tram, or train. The Florence Santa Maria Novella station integrates amenities to enhance your comforts, such as a pharmacy, ticket office, bank, luggage storage office, eateries, and restrooms.
Arrival train station: The train from Florence to Fiumicino can stop at Fiumicino Aeroporto or Parco Leonardo, with the former being the main station for most operations. Fiumicino Aeroporto is around 2.2 miles (3.63. km) from the town’s center and accessible in about 21 min using the SIT Bus. The station has shops, eateries, restrooms, shower facilities, a rest zone, and free Wi_Fi.
Trenitalia and Italo are the companies servicing the trains from Florence to Fiumicino. Trenitalia provides most daily operations, with Italo providing roughly 24 rides each day. The latter also operates as a connecting train, requiring you to transfer to a Trenitalia service to reach Fiumicino.
The voyage from Florence to Fiumicino by train does not offer overnight services. Nonetheless, you can find some evening and early night rides that reach Fiumicino from around 8:10 p.m. to 11:07 p.m. The final departure at approximately 8.48 p.m. has the latest arrival time. Most trains leaving after around 7:28 p.m. reach Fiumicino past 10:00 p.m. It is necessary to note that the service that begins at roughly 6:28 p.m. finishes its course at around 10:33 p.m.
Trenitalia offers many Florence to Fiumicino trains, with about 45 to 50 services every day. It offers two non_stop operations at around 8:26 a.m. via Frecciargento. The other direct train leaves at approximately 11:48 a.m. via Frecciarossa. Trenitalia runs all other services with a transfer, offering varying durations of about 2 h 06 min to over 5 h.
Italo trains to Fiumicino from Florence typically can take around 2 h 27 min to 2 h 57 min, offering moderately efficient durations on the schedules. The company also features one transfer on the course, where you switch to a Trenitalia train to reach your final stopping station. Notably, Italo does not offer non_stop rides on this route.
Trains add the fewest greenhouses compared to other high_volume public transportation options. This quality makes it the greenest mode of travel that enhances daily lives without endangering future generation needs. Trains contribute to sustainability efforts by offering railways more resilient to climate change. They also help maintain and preserve habitats by caring for the environment around the railways.
Trenitalia offers second_class coaches on Regionale models, first class on Frecciargento, and Business and Executive classes onboard the Frecciarossa. The Business and Executive services include free Wi_Fi, power plugs, a silent area, wide seats, available food, and free drinks. Even though Trenitalia offers a free baggage policy, you want to carry the standard two suitcases and one carry_on piece that can fit on your lap. You can also place a bicycle in an 80×110×40cm bag and present it as checked luggage. Additionally, you can put a small cat or dog in a compact 70×30×50cm carrier for the journey. Trenitalia has support personnel to assist disabled travelers. Italo provides Smart and Economy classes on its Florence to Fiumicino trains, availing reclining leather seats, free Wi_Fi, a snack area, and comfortable luggage compartments. The company lets you bring two luggage items, each not exceeding 30×70×90cm. Italo permits you to fold a bike into a bag and bring it as checked luggage. You can also take a carry_on bag that fits on your lap, which you can place in the overhead storage space or beneath your seat. In addition, you can travel with a small pet in a carrier weighing up to 22 lbs (10 kg). Italo has assistance services to support disabled passengers during the trip.
Getting a ticket in advance is convenient for finding lower fare prices when voyaging from Florence to Fiumicino via train. It is also best to be flexible with your travel dates, enabling you to choose a departure with cheaper tickets. Apart from these, you can pick the slower trains or ones with multiple stops because they often provide lower ticket rates.For more information you can check out the Omio Magazine


A trip to Fiumicino allows you to visit ancient sites such as the Ostia Antica, where you can view the remains of an ancient Roman city. The archeological site features impressive mosaics, magnificent frescoes, and well_preserved buildings. You can also look at sizeable structures from the Roman Imperial era at another archeological park, the Area Archeologica del Porto di Traiano. Besides this, you can go to the Pontile di Ostia if you travel with companions. The 150_meter jetty incorporates an observation point, where you can enjoy sweeping vistas of the water and sky. You can take kids to Mediterraneo Beach for a fun_filled day on the beautiful shores. Stabilimento Balneare Tirreno offers a quality beach for relaxing with friends and family. The spot also includes a playground to increase convenience and excitement when accompanied by young ones. You can unwind and dine on international and local cuisine at excellent Fiumicino restaurants, such as Il Ristorantino, Pascucci Al Porticciolo, and La Pecora Nera.Top parks to tour in Fiumicino for nature lovers include:
Find answers to the most common questions about traveling from Pisa to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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