- Must visit
Museo Regionale Interdisciplinare di Messina
Messina’s main museum preserves major Sicilian artworks, including masterpieces by Caravaggio and Antonello-linked treasures, essential for art lovers.
Cheapest price on Sep 19
$87
Average ticket price on Sep 19
$105
Fastest journey on Sep 19
10 h 20 m
Average journey duration on Sep 19
11 h 41 m
Trains on Sep 19
10
Distance
751 km
The best way to find a cheap train ticket from Pisa to Messina is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Messina will cost around $105 if you buy it on the day, but the cheapest tickets can be found for only $87.
It's difficult to get from Pisa to Messina without transferring at least once.
Intercity 501 · Intercity 727
Intercity 501 · Intercity 727
FRECCIARGENTO 8591+
InterCityNotte 1959
InterCityNotte 799+
Intercity 723
InterCityNotte 799+
Intercity 723
FRECCIAROSSA 9613+
Intercity 727+
FRECCIARGENTO 8551
Regionale 18250+
FRECCIAROSSA 9503+
Intercity 723
FRECCIARGENTO 8583+
Intercity 727
FRECCIAROSSA 9653+
InterCityNotte 1955+
FRECCIABIANCA 8619
FRECCIARGENTO 8591+
InterCityNotte 1959Omio recommends booking the bus as it is the most popular option from Pisa to Messina among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $120 For those with little time, consider booking a flight, which has an average total journey time of 4h 27m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of $120, while a flight costs an average of $196.
Distance: 466 miles (751 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$141 Average price | $120 Average price Cheapest | $196 Average price | $256 Average price (fuel + tolls) |
12h 7m Average total duration 11h 37m Onboard + 30m Additional time* | 15h 24m Average total duration 14h 54m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 2h 27m Onboard + 2h 0m Additional time* | 10h 31m Average total duration (door-to-door) |
0.2 - 0.7kg CO2 emissions Lowest | 0.8 - 1.9kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Messina:
A bus is $21 less than a train for this route with tickets for a train from Pisa to Messina costing on average $141.
A bus is $76 less than a flight for this route with tickets for a flight from Pisa to Messina costing on average $196.
Other travel options to Messina take longer:
Train takes on average 11h 37m.
Bus takes on average 14h 54m.
Tickets start at around $141 compared to roughly $256 in fuel and tolls — a saving of about $115. The journey takes 11h 37m versus 10h 31m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Pisa to Messina trains for today, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:32 PM Pisa | 12h33 | 6:05 AM Messina | 0 transfersDirect | |
| Saturday, September 19 | |||||
InterCityNotte 799+ Intercity 723 | 2:21 AM Pisa Centrale | 13h14 | 3:35 PM Messina Centrale | 1 transfer | |
InterCityNotte 799+ Intercity 723 | 2:21 AM Pisa Centrale | 13h14 | 3:35 PM Messina Centrale | 1 transfer | |
InterCityNotte 799+ Intercity 723+ Regionale 21693 | 2:21 AM Pisa Centrale | 14h20 | 4:41 PM Fiumara Gazzi | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa to Messina run on average 10 times per day, taking around 11h 37m. Cheap train tickets for this journey start at $75 but you can travel from only $52 by flight.
The earliest train runs at 00:01, the last at 23:40. The fastest train covers the 466 miles (751 km) distance in 9h 38m.
Distance 466 miles (751 km) |
Average train duration 11h 37m |
Cheapest ticket price $75 |
Trains per day 10 |
Fastest train 9h 38m |
First train 12:01 AM |
Last train 11:40 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sun |
Best time to book 1 day |
Discover the best of Messina — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Messina trip today.
Messina’s main museum preserves major Sicilian artworks, including masterpieces by Caravaggio and Antonello-linked treasures, essential for art lovers.
A church museum displaying liturgical art, silverwork, and historic objects tied to Messina Cathedral and the city’s religious heritage.
A small local gallery and exhibition space used for cultural displays, suitable for visitors seeking contemporary community art in Messina.
Messina’s main cathedral square is the city’s ceremonial heart, ideal for seeing the Duomo, fountain, and clock tower together.
This scenic viewpoint area beside Cristo Re offers one of the best panoramas over Messina, the harbor curve, and Calabria beyond.
This central piazza is dominated by Orion Fountain and elegant facades, making it one of the city’s most photogenic public spaces.
A layered baked pasta timbale with ragù, eggplant, cheese, and sometimes meatballs. A festive Sicilian classic closely tied to family Sunday meals.
A crisp fried rice ball, usually filled with ragù, peas, and cheese. A beloved Sicilian street food found in bars and bakeries across Messina.
Soft sweet brioche served with granita, especially for breakfast. In Messina it is a warm-weather ritual and a signature part of Sicilian café culture.
Refined Michelin-starred dining with creative Sicilian seafood and tasting menus in an elegant setting inside Hotel Messenion.
Historic pastry café famed for granita, brioche, gelato, and Sicilian breakfast classics. A traditional stop with a strong local reputation.
Well-known seafood restaurant serving swordfish, shellfish, and classic Sicilian fish dishes in a polished but welcoming atmosphere.
Moderate for Italy. Rooms and meals are often cheaper than in Rome or Milan, while local buses and ferries stay reasonably priced for tourists.
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% in restaurants for good service, and round up taxi fares.
Official public transport app
Messina Centrale -> Piazza Duomo, Messina
Find answers to the most common questions about traveling from Pisa to Messina by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Messina, this guide helps you travel smarter and with confidence.

Most Pisa to Messina trains use the Pisa Centrale to Messina Centrale station pair. Use this guide to compare Pisa and Messina train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Pisa, Aeroporto Galilei Di Pisa is 1 km from Pisa city centre. Check local transport options before travel.
Pisa, Aeroporto Galilei Di Pisa has practical services for this route, including Accessibility.
Accessibility facilities are available at Pisa, Aeroporto Galilei Di Pisa.
Here are some other resources that might have the information you need