Travel Information
Compare bus and train for Pisa to Rome
Omio recommends booking the train as it is the most popular option from Pisa to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a train which can get you there in 3h 36m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $15, and a train costs an average of $25.
Distance: 164 miles (265 km)
Compare train with
Most popular Train | Bus |
|---|---|
$33 Average price | $24 Average price Cheapest |
4h 6m Average total duration Fastest 3h 36m Onboard + 30m Additional time* | 5h 15m Average total duration 4h 45m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Rome
How to get from Pisa to Rome by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Rome is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBus · FlixBusFastest
FRECCIARGENTO 8551Other options
ETRUSCHI LINE 4131
ETRUSCHI LINE 4133
ETRUSCHI LINE 4135
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FlixBus
FlixBus · FlixBusFind all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to Travel from Pisa to Rome
Traveling from Pisa to Rome is simple and shouldn't take more than 3 or 4 hours, whether you take a bus or train. The fastest way to travel in Italy is by a Trenitalia express, which takes just over 2 hours, but there are buses that don't take much longer. Be sure to check both the bus and train schedules before traveling, as some services are significantly slower than others.
Trains from Pisa to Rome | Buses from Pisa to Rome | Return trips from Rome to Pisa
Pisa to Rome Travel Comparison
Average Price |
Travel Time |
Cheapest Time to Book |
|
|---|---|---|---|
|
€13 |
5:15 h |
1 Day Ahead |
|
€31 |
2:11 h |
1 Week Ahead |
What is the best way to travel from Pisa to Rome?
Cheapest way to travel from Pisa to Rome
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Taking the bus is the cheapest way to travel from Pisa to Rome. Buses traveling from Pisa to Rome depart from Pisa's Autostazione Via Pietrasantina and take just over 5 hours to arrive at Rome's Tiburtina bus station. Between 2-5 buses travel from Pisa to Rome to Pisa per day. Bus companies that travel from Pisa to Rome include Baltour and Flixbus. Ridesharing services like BlaBlaCar also frequently offer trips from Pisa to Rome. Rideshares often travel from Pisa to Rome more frequently than buses.
Fastest way to travel from Pisa to Rome
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Taking the train is the fastest way to travel from Pisa to Rome. Trains traveling from Pisa to Rome depart from Pisa Centrale train station and take as little as 2 hours to arrive at either Rome's Termini, Tiburtina, or Ostiense train station when traveling on a high-speed train. Over 50 trains travel from Pisa to Rome every day, with the earliest train departing Pisa at 1:41 a.m. All trains that travel from Pisa to Rome are operated by Trenitalia with a variety of train types available. Some trains traveling from Pisa to Rome require a transfer in Florence.
Most popular way to travel from Pisa to Rome

Taking the train is the most popular way to travel from Pisa to Rome. Traveling from Pisa to Rome by high-speed train is approximately 3 hours faster than taking the bus. Trains are also only €18 more expensive than buses on average. Rome and Pisa are located too close together to make flying a prudent option. Buses remain an attractive option for people who would prefer to save while traveling from Pisa to Rome. Rideshares offer another alternative that are usually both cheaper and faster than buses.
How to get from Pisa to Rome
The Best Way According to our Users
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FAQs: Travel from Pisa to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Rome.

This is compared to other travel options from Pisa to Rome:
A bus is $10 (€8) less than a train for this route with tickets for a train from Pisa to Rome costing on average $25 (€20).
Other travel options to Rome take longer:
Bus takes on average 4h 14m.
- Around 45 trains per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Pisa and Rome as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Pisa Centrale and arrive in Rome Termini.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Roma, Autostazione Tiburtina.
- Travel with FlixBus, Marino Autolinee, Busitalia, BlaBlaCar, Itabus to go to Rome by bus.
- Travel with ITA to go to Rome by flight.
- Travel with Frecciabianca, Regionale, Italo, Intercity, Frecciargento, Frecciarossa, Intercity Notte to go to Rome by train.
- 8 direct buses per day with FlixBus, Marino Autolinee, Busitalia, BlaBlaCar, Itabus.
- 18 direct trains per day with Frecciabianca, Regionale, Intercity, Frecciargento, Frecciarossa, Intercity Notte.
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