Mainz to Prague train with České dráhy

Tue, Nov 03
+ Add return
alex-Länderbahn und Vogtlandbahn-GmbH
Deutsche Bahn
České dráhy
Leo Express
Regionale
2,000+ travel companies
alex-Länderbahn und Vogtlandbahn-GmbH
Deutsche Bahn
České dráhy
Leo Express
Regionale
2,000+ travel companies
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The cheapest and fastest trains from Mainz to Prague

Showing times, prices and bookable tickets for Nov 03
Cheapest price on Nov 03
$46
Average ticket price on Nov 03
$140
Fastest journey on Nov 03
8 h 5 m
Average journey duration on Nov 03
8 h 24 m
Trains on Nov 03
9
Distance
439 km
Cheap tickets

The best way to find a cheap train ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Mainz to Prague will cost around $140 if you buy it on the day, but the cheapest tickets can be found for only $46.

Fast trains

It's difficult to get from Mainz to Prague without transferring at least 3 times.

  • Deutsche BahnS8 · ICE 527 · 3565 · Bus RE25
    4 transfers
  • Deutsche BahnS8 · ICE 621 · 3569 · Bus RE25
    4 transfers
  • Deutsche BahnICE 25 · 3569 · Bus RE25 · EX 359
    3 transfers
  • Deutsche Bahn29247 · ICE 1557 · BUS 10383 · RJ 383
    3 transfers
  • Deutsche Bahn4257 · ICE 1559 · S1 · Os 28010
    4 transfers

Journey information

Overview: Train from Mainz to Prague

GermanyGermany
CzechiaCzechia
Icon of train

Trains from Mainz to Prague run on average 7 times per day, taking around 7h 40m. Cheap train tickets for this journey start at $13 if you book in advance.

The earliest train runs at 00:30, the last at 23:50. The fastest train covers the 272 miles (439 km) distance in 6h 43m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Plan this route

Journey facts

  • Distance272 miles (439 km)
  • Average train duration7h 40m
  • Cheapest ticket price$13
  • Trains per day7
  • Fastest train6h 43m
  • First train12:30 AM
  • Last train11:50 PM
  • Cheapest MonthJul
  • Cheapest DayTue
  • High SeasonOct - Dec
  • Low SeasonJul - Sep
  • Busiest DaySat
  • Least Busy DaySun
  • Best time to book28 days

Understand & plan this route

Explore this journey

Book with confidence

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Frequently asked questions about your Mainz to Prague trip

Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Mainz to Prague.

Train ticket prices from Mainz to Prague can vary. The cheapest ticket starts at $13, while the average price is around $150.
The train from Mainz to Prague takes 6h 43m and runs 7 per day.
The distance by train from Mainz to Prague is 272 miles (439 km).
The first train from Mainz to Prague leaves at 12:30 AM.
The last train from Mainz to Prague leaves at 11:50 PM.
Yes, there is a direct train from Mainz to Prague. This service operates 0 times per day, provided by Leo Express.

Live departures

Mainz to Prague train times

The table below shows live departures for Mainz to Prague trains for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Deutsche BahnS8 · ICE 527 · 3565 · Bus RE258:02 AM Mainz Hbf
8h19
4:21 PM Prague hlavní nádraží4 transfers
Deutsche Bahn29247 · ICE 1557 · BUS 10383 · RJ 3838:27 AM Mainz Hbf
8h58
5:25 PM Prague hlavní nádraží3 transfers
České dráhyIC 2049 · rj 385
On time
9:20 AM Mainz Hbf
12h05
9:25 PM Prague hlavní nádraží		1 transfer
Deutsche BahnICE 25 · 3569 · Bus RE25 · EX 359
On time
9:42 AM Mainz Hbf
8h39
6:21 PM Prague hlavní nádraží		3 transfers
České dráhyICE 25 · R 3567 · EC 61359 · EC 359
On time
9:42 AM Mainz Hbf
8h39
6:21 PM Prague hlavní nádraží		3 transfers
Deutsche BahnS8 · ICE 621 · 3569 · Bus RE2510:02 AM Mainz Hbf
8h19
6:21 PM Prague hlavní nádraží4 transfers
Deutsche Bahn4257 · ICE 1559 · S1 · Os 2801010:10 AM Mainz Hbf
9h00
7:10 PM Prague hlavní nádraží4 transfers
Deutsche Bahn4257 · ICE 1559 · RJ 177
On time
10:10 AM Mainz Hbf
9h05
7:15 PM Prague-Holešovice		2 transfers
Deutsche Bahn29511 · ICE 690 · IC 2441 · RJ 177
On time
11:10 AM Mainz Hbf
8h05
7:15 PM Prague-Holešovice		3 transfers

This is the last train of the day.

Find all the dates and times for this journey

Why should you book Mainz to Prague trains with Omio?

alex-Länderbahn und Vogtlandbahn-GmbH as well as Deutsche Bahn, České dráhy, Leo Express and more offer trains services from Mainz to Prague.
Omio is an official ticket reseller for all your travel options from Mainz to Prague.

Why book with Omio vs alex-Länderbahn und Vogtlandbahn-GmbH?

  • Compare with other providers: On Omio, you can not only buy tickets for alex-Länderbahn und Vogtlandbahn-GmbH, but also compare tickets for the likes of Deutsche Bahn, České dráhy or Leo Express to find the best option for your trip from Mainz to Prague.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare alex-Länderbahn und Vogtlandbahn-GmbH with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz to Prague.

Why book with Omio over Wanderu, Trainline or Raileurope?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Deutsche Bahn, České dráhy or Leo Express to find the best option for your trip from Mainz to Prague.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz to Prague.

Train companies

Train companies from Mainz to Prague

Trains from Mainz to Prague with České dráhy, Deutsche Bahn, and alex-Länderbahn und Vogtlandbahn-GmbH. Night trains available on this route with České dráhy and Deutsche Bahn. High-speed trains available on this route with Deutsche Bahn. Regional trains available on this route with České dráhy, Deutsche Bahn, and alex-Länderbahn und Vogtlandbahn-GmbH. Use the details below to compare onboard facilities.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Deutsche Bahn Duration
6h 45m
Cheapest Deutsche Bahn Price
$58
Deutsche Bahn frequency
3 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
Learn more about Deutsche Bahn

alex-Länderbahn und Vogtlandbahn-GmbH

About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
Average alex-Länderbahn und Vogtlandbahn-GmbH Duration
7h 2m
Cheapest alex-Länderbahn und Vogtlandbahn-GmbH Price
$13
alex-Länderbahn und Vogtlandbahn-GmbH frequency
2 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone
Learn more about alex-Länderbahn und Vogtlandbahn-GmbH

Leo Express

About
Leo Express is a Czech train and bus company offering fast and comfortable travel across the Czech Republic and to international destinations. Its modern, air-conditioned fleet includes Leo Express InterCity trains, reaching speeds of up to 160 km/h, as well as Express and Regional services for more leisurely journeys. Ticket types include Economy, Economy Plus, Business, and Premium, alongside single, return, and group tickets, with discounts available for students, seniors, and children. Onboard amenities may feature a café car, restaurant car, and bar car. Popular routes include Prague to Ostrava, Brno, and Olomouc, as well as international connections to Vienna, Budapest, and Krakow.
Luggage & cancellation policy
Average Leo Express Duration
9h 54m
Cheapest Leo Express Price
$21
Leo Express frequency
3 a day
Luggage included
1 piece of hand luggage (max 8kg) and 1 piece of luggage (max 15kg)
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
According to fare conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Snacks and beverages available for purchase from onboard menu
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed for fee, larger dogs require ticket and muzzle

České dráhy

About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average České dráhy Duration
6h 43m
Cheapest České dráhy Price
$50
České dráhy frequency
4 a day
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the train
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.
Learn more about České dráhy

Companies, tickets, and onboard amenities between Mainz and Prague

Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.

Yes, there is a high-speed train from Mainz to Prague.
Yes, there is a night train from Mainz to Prague.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.

Complete guide to Prague

Things to do in Prague

Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.

  • Must visit

National Museum

Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.

View on mapVisit website
  • Must visit

Jewish Museum in Prague

Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.

View on mapVisit website
  • Recommended

National Gallery Prague – Schwarzenberg Palace

Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.

View on mapVisit website

Czech koruna (Kč)

Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.

Average meal costs

Budget
Kč150-Kč250 for fast food or street food.
Mid-range
Kč300-Kč600 per person for a meal.
Fine dining
Kč1,200+ per person for upscale restaurants.
Coffee
Kč55-Kč85 for cappuccino.

Tipping culture

Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.

Plan your visit to Prague

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.

The train journey from Mainz to Prague offers scenic views, including the picturesque Rhine Valley with its castles and vineyards, and beautiful landscapes in Bavaria and the Czech countryside.
Popular day trips by train from Prague include Kutná Hora, Plzeň, Pardubice, Hradec Králové, Karlštejn.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Trains from Mainz to Prague

Find answers to the most common questions about traveling from Mainz to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Yes, you can take the train from Mainz to Prague.

popular train stations

Popular train stations from Mainz to Prague

Most Mainz to Prague trains use the Mainz Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Mainz and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Mainz
Arrival train stations in Prague

Which Mainz station do trains to Prague leave from?

Trains from Mainz to Prague leave from Mainz Hbf. The station is 1 miles (2 km) from Mainz city centre at Mainz Hbf, Bahnhofplatz 1, 55116 Mainz.
Mainz HbfMainz Hbf, Bahnhofplatz 1, 55116 MainzWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Mainz Hbf from Mainz city centre

Mainz Hbf is 2 km from Mainz city centre. Public transport options include:

Bus92, 76, 62 · 9m · every ~13 min
93, 76, 65, 64 · 12m · every ~6 min
Tram52, 50 · 12m · every ~11 min

Mainz Hbf train station facilities and services

Mainz Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: Mangal, Asia Wok, Bistrorante Midi, McDonald's

Wi-Fi and ATMs

Wi-Fi is available at Mainz Hbf. ATMs are available at Mainz Hbf.

Tickets and information

Ticket office support is available at Mainz Hbf. Information desks are available at Mainz Hbf.

Luggage and lost property

Luggage storage is available at Mainz Hbf. Lost and found is available at the station.

Parking, taxis and toilets

Available at Mainz Hbf: Parking, Taxis, WC.

Bike and car services

Available at Mainz Hbf: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Mainz Hbf.

Shops, hotels and contact

Nearby hotels include Advena Europa Hotel, GuestHouse Mainz, Terminus, Hotel Moguntia.

More about Mainz Hbf
Mainz Römisches TheaterMainz Römisches Theater, Holzhofstr. 1a, 55116 MainzWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Mainz Römisches Theater from Mainz city centre

Mainz Römisches Theater is 1 km from Mainz city centre. Public transport options include:

Bus93, 66, 65, 64 · 3m · every ~10 min
93, 66, 65, 64 · 7m · every ~10 min

Mainz Römisches Theater train station facilities and services

Mainz Römisches Theater has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: McDonald's, Cafe Extrablatt, Hans im Glück, The Big Easy

Wi-Fi and ATMs

Wi-Fi is available at Mainz Römisches Theater. ATMs are available at Mainz Römisches Theater.

Tickets and information

Ticket office support is available at Mainz Römisches Theater. Information desks are available at Mainz Römisches Theater.

Luggage and lost property

Luggage storage is available at Mainz Römisches Theater. Lost and found is available at the station.

Parking, taxis and toilets

Available at Mainz Römisches Theater: Parking, Taxis, WC.

Bike and car services

Available at Mainz Römisches Theater: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Mainz Römisches Theater.

Shops, hotels and contact

Nearby hotels include Hyatt Regency Mainz, Favorite Parkhotel, Ibis Hotel Mainz City, Hof Ehrenfels.

More about Mainz Römisches Theater
Bahnstrecke Mainz–MannheimMainz, GermanyWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Bahnstrecke Mainz–Mannheim from Mainz city centre

Bahnstrecke Mainz–Mannheim is 2 km from Mainz city centre. Public transport options include:

Bus92, 62 · 8m · every ~8 min
660S · 18m
93, 76, 65, 64 · 31m · every ~6 min
Tram52 · 17m · every ~6 min

Bahnstrecke Mainz–Mannheim train station facilities and services

Bahnstrecke Mainz–Mannheim has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several restaurants available on-site.

Wi-Fi and ATMs

Free Wi-Fi available in waiting areas. ATMs are aTMs located near ticket office.

Tickets and information

Ticket office support is available at Bahnstrecke Mainz–Mannheim.

Parking, taxis and toilets

Available at Bahnstrecke Mainz–Mannheim: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Bahnstrecke Mainz–Mannheim: Wheelchair accessible with elevators.

Train stations for Mainz to Prague

Check train stations information for Mainz and Prague, including where trains depart and arrive on this route.

The train station in Mainz that goes to Prague is Mainz Hbf, which connects to Praha hlavní nádraží.

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