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The cheapest and fastest trains from Mainz to Prague
Showing times and prices for Dec 22
Cheapest price
$154
Average price
$195
Fastest journey
7 h 46 m
Average duration
8 h 19 m
Trains per day
4
Distance
439 km
Cheap tickets
The best way to find a cheap train ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz to Prague will cost around $195 if you buy it on the day, but the cheapest tickets can be found for only $154.
Fast trains
It's difficult to get from Mainz to Prague without transferring at least 2 times.
VIA 25007 · ICE 1557 · rj 38308:39AM8h46
Mainz-Kastel station05:25PMPrague hlavní nádraží
$1541One-way
2 transfers
VIA 25009 · ICE 692 · IC 2443 · rj 38309:39AM7h46
Mainz-Kastel station05:25PMPrague hlavní nádraží
$1541One-way
3 transfers
VIA 25055 · ICE 527 · R 3565 · EC 35708:09AM8h12
Mainz-Kastel station04:21PMPrague hlavní nádraží
$2131One-way
3 transfers
VIA 25007 · ICE 1557 · S 31739 · Os 544808:39AM8h31
Mainz-Kastel station05:10PMPrague hlavní nádraží
$2611One-way
4 transfers
VIA 25009 · ICE 692 · IC 2443 · rj 38309:39AM7h46
Mainz-Kastel station05:25PMPrague hlavní nádraží
$1541One-way
3 transfers
VIA 25055 · ICE 527 · R 3565 · EC 35708:09AM8h12
Mainz-Kastel station04:21PMPrague hlavní nádraží
$2131One-way
3 transfers
VIA 25007 · ICE 1557 · S 31739 · Os 544808:39AM8h31
Mainz-Kastel station05:10PMPrague hlavní nádraží
$2611One-way
4 transfers
VIA 25007 · ICE 1557 · rj 38308:39AM8h46
Mainz-Kastel station05:25PMPrague hlavní nádraží
$1541One-way
2 transfers
Travel Information
Compare bus, train, and flight for Mainz to Prague
Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 35m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a flight costs an average of €50.
Distance: 272 miles (439 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€83 Average price | €37 Average price Cheapest | €119 Average price |
8h 3m Average total duration 7h 33m Onboard + 30m Additional time* | 7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 4h 35m Average total duration Fastest 1h 35m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Prague train times
The table below shows live departures for Mainz to Prague trains for tomorrow, Monday, December 22. You can also manually refresh the results below to see updated train journeys.
Last updated at 11:06 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| VIA 25055 · ICE 527 · R 3565 · EC 357 | 7:09 AM Mainz-Kastel station | 8h12 | 3:21 PM Prague hlavní nádraží | 3 transfers | |
| VIA 25007 · ICE 1557 · rj 383 | 7:39 AM Mainz-Kastel station | 8h46 | 4:25 PM Prague hlavní nádraží | 2 transfers | |
| VIA 25007 · ICE 1557 · S 31739 · Os 5448 | 7:39 AM Mainz-Kastel station | 8h31 | 4:10 PM Prague hlavní nádraží | 4 transfers | |
| VIA 25009 · ICE 692 · IC 2443 · rj 383 | 8:39 AM Mainz-Kastel station | 7h46 | 4:25 PM Prague hlavní nádraží | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mainz to Prague trains with Omio?
Deutsche Bahn (ICE,RE,EC,IC) as well as Alex offer trains services from Mainz to Prague. Omio is an official ticket reseller for all your travel options from Mainz to Prague.
Why book with Omio vs Deutsche Bahn (ICE,RE,EC,IC)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (ICE,RE,EC,IC), but also compare tickets for the likes of Alex to find the best option for your trip from Mainz to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (ICE,RE,EC,IC) with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz to Prague.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (ICE,RE,EC,IC) tickets can be bought on Deutsche Bahn (ICE,RE,EC,IC)'s website or third party sellers, Omio allows you to compare with the likes of Alex to help you choose the right option for your journey from Mainz to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz to Prague.
Journey information
Overview: Train from Mainz to Prague
Germany
Czechia
Trains from Mainz to Prague run on average 8 times per day, taking around 7h 33m. Cheap train tickets for this journey start at $41 (€33) but you can travel from only $31 (€25) by bus.
The earliest train runs at 00:30, the last at 23:41. The fastest train covers the 272 miles (439 km) distance in 7h 24m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $31 (€25)
Distance 272 miles (439 km) |
Average train duration 7h 33m |
Cheapest ticket price $41 (€33) |
Trains per day 8 |
Fastest train 7h 24m |
First train 00:30 |
Last train 23:41 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $31 (€25)
Train companies: Deutsche Bahn, Alex from Mainz to Prague trainsDeutsche Bahn, Alex trains will get you between Mainz and Prague from $31 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
7h 24m
Cheapest Price
$75 (€60)
Deutsche Bahn frequency
5 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
Alex
About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
Alex frequency
3 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone
FAQs: Trains from Mainz to Prague
Find answers to the most common questions about traveling from Mainz to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
A day trip from Mainz to Prague is not feasible since the journey takes 7h 24m and covers 272 miles (439 km). Trains run 8 times per day.
To fully experience Prague, 3 to 4 days are recommended, allowing time to explore key attractions like Prague Castle, Charles Bridge, Old Town Square, and the Jewish Quarter, as well as enjoy local cuisine and culture.
Train ticket prices from Mainz to Prague can vary. The cheapest ticket starts at $41 (€33), while the average price is around $104 (€83).
The train from Mainz to Prague takes 7h 24m and runs 8 per day.
In Prague, you can enjoy panoramic views from Petrin Hill and visit attractions like the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady with its trendy bars and cafes, or take a boat cruise on the Vltava River for unique views of the city's landmarks. Delve into Czech history at the National Museum, and enjoy a classical music concert in one of the city's historic venues. Must-see sights include Prague Castle, Charles Bridge, Old Town Square with the Astronomical Clock, St. Vitus Cathedral, and the historic Jewish Quarter.
The cheapest way to get from Mainz to Prague is by bus, with a cost of around $31 (€25).
The train journey from Mainz to Prague offers scenic views, including the picturesque Rhine Valley with its castles and vineyards, and beautiful landscapes in Bavaria and the Czech countryside.
The first train from Mainz to Prague leaves at 12:30 AM.
Yes, you can take the train from Mainz to Prague.
The last train from Mainz to Prague leaves at 11:41 PM.
The distance by train from Mainz to Prague is 272 miles (439 km).
There is no direct train service currently available from Mainz to Prague.
The train station in Mainz that goes to Prague is Mainz Hbf, which connects to Prague hlavní nádraží.
Unfortunately, there is no night train available from Mainz to Prague.
popular train stations
Popular train stations from Mainz to Prague
Mainz
Prague
The major train station for departures in Mainz is Mainz Hbf. Find all the information you need to know about services, amenities and connections at Mainz Hbf for your trip from Mainz to Prague.
Amenities at train station
Wifi
Lockers
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Lounge
Lost and Found Office
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
Distance to city center
2 kmDining
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
Hotel
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
Amenities at train station
WifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Distance to city center
1 kmDining
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
Hotel
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
Mainz-Laubenheim
Amenities at train station
WifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Distance to city center
3 kmDining
- Zum Laubenheimer Ried - Da Giovanni
- Mainzer Hof
- Pizza Roma
- Bäckerei Werner
Hotel
- Goldene Ente
The major train station for arrivals in Prague is Praha hlavní nádraží. Find all the information you need to know about services, amenities and connections at Praha hlavní nádraží for your journey to Prague from Mainz.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotel
ShowerLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
1 km
Number of platforms
7Wifi
- Free
Parking
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
Dining
- Restaurant Fantova Kavárna
- Sushi Time
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- CZK 10
Hotel
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
Shower
- Cost CZK 100
Lounge
- Located in the main hall
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
Public transit options for Praha hlavní nádraží
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
Praha Masarykovo Nádraží
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Number of platforms
5Wifi
- Free
Parking
- Parking is available nearby with several public parking options.
Dining
- Restaurant Kotleta
- Café Imperial
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- CZK 10
Hotel
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
Public transit options for Praha Masarykovo Nádraží
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Praha Výstaviště
information
Most popular train connections from Mainz
More options for your journey from Mainz to Prague
Here are some other resources that might have the information you need
Most popular trains to and from Prague and Mainz
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