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Journey information
Overview: Mainz to Prague flight
Germany
Czechia
Flights from Mainz to Prague depart on average 73 times per day, taking around 1h 29m. Cheap flight tickets for this journey start at $99 (€80) but you can travel from only $32 (€26) by bus.
There are 9 flights per day. The earliest flight runs at 05:15, the last at 22:15. The fastest flight covers the 272 miles (439 km) distance in 1h 0m. June is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $32 (€26)
Distance 272 miles (439 km) |
Average flight duration 1h 29m |
Cheapest ticket price $99 (€80) |
Flights per day 73 |
Direct flights 9 |
Fastest flight 1h 0m |
Cheapest month June |
First flight 05:15 |
Last flight 22:15 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $32 (€26)
The cheapest and fastest flights from Mainz to Prague
Showing times and prices for Mar 23
Cheapest price
$314
Average price
$655
Fastest journey
1 h
Average duration
1 h 4 m
Flights per day
73
Distance
439 km
Cheap tickets
The best way to find a cheap flight ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz to Prague will cost around $655 if you buy it on the day, but the cheapest tickets can be found for only $314.
Fast flights
Of the 73 flights that leave Mainz for Prague onMon, Mar 23, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct flights cover the 439 km distance in an average of 1 h 4 m but if you time it right, some flights will get you there in just 1 h .
On Mon, Mar 23 the longest flights will take 1 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
LO380 · LO52307:50PM13h00
Frankfurt am Main Airport08:50AMPrague Vaclav Havel Airport
$3141One-way
1 transfer
LO380 · LO52707:50PM16h20
Frankfurt am Main Airport12:10PMPrague Vaclav Havel Airport
$3141One-way
1 transfer
LO380 · LO52907:50PM25h55
Frankfurt am Main Airport09:45PMPrague Vaclav Havel Airport
$3141One-way
1 transfer
LO380 · LO52107:50PM21h25
Frankfurt am Main Airport05:15PMPrague Vaclav Havel Airport
$3141One-way
1 transfer
LO380 · LO52507:50PM23h00
Frankfurt am Main Airport06:50PMPrague Vaclav Havel Airport
$3141One-way
1 transfer
DE440702:15PM1h00
Frankfurt am Main Airport03:15PMPrague Vaclav Havel Airport
$4581One-way
0 transfers
LH140209:20PM1h05
Frankfurt am Main Airport10:25PMPrague Vaclav Havel Airport
$3241One-way
0 transfers
LH139208:45AM1h05
Frankfurt am Main Airport09:50AMPrague Vaclav Havel Airport
$4441One-way
0 transfers
LH565405:10PM1h05
Frankfurt am Main Airport06:15PMPrague Vaclav Havel Airport
$5261One-way
0 transfers
EN895805:10PM1h05
Frankfurt am Main Airport06:15PMPrague Vaclav Havel Airport
$5261One-way
0 transfers
Travel Information
Compare bus, train, and flight for Mainz to Prague
Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $99.
Distance: 272 miles (439 km)
Compare flight with
| Flight | Most popular Train | Bus |
|---|---|---|
$202 Average price | $107 Average price | $47 Average price Cheapest |
4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 9h 5m Average total duration 8h 35m Onboard + 30m Additional time* | 7h 40m Average total duration 7h 10m Onboard + 30m Additional time* |
1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions |
Most popular airline |  Most popular train company |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Prague flight times
The table below shows live departures for Mainz to Prague flights for today, Sunday, March 22. You can also manually refresh the results below to see updated flight journeys.
Last updated at 10:15 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:00 PM Mainz | 1h05 | 5:05 PM Prague | 0 transfersDirect | |
 | 5:30 PM Mainz | 1h20 | 6:50 PM Prague | 0 transfersDirect | |
| 7:10 PM Mainz | 1h00 | 8:10 PM Prague | 0 transfersDirect | |
| Monday, March 23 | |||||
OS8914+ OS643 | 5:50 AM Cologne Bonn Airport | 3h35 | 9:25 AM Prague Vaclav Havel Airport | 1 transfer | |
| OS218 · OS643 | 5:50 AM Frankfurt am Main Airport | 3h35 | 9:25 AM Prague Vaclav Havel Airport | 1 transfer | |
 KL1814+ KL1357 | 5:55 AM Frankfurt am Main Airport | 10h40 | 4:35 PM Prague Vaclav Havel Airport | 1 transfer | |
| KL1814+KL1353 | 5:55 AM Frankfurt am Main Airport | 3h55 | 9:50 AM Prague Vaclav Havel Airport | 1 transfer | |
| KL1814+KL1355 | 5:55 AM Frankfurt am Main Airport | 6h50 | 12:45 PM Prague Vaclav Havel Airport | 1 transfer | |
SN7016+ SN2809 | 6:20 AM Frankfurt am Main Airport | 3h30 | 9:50 AM Prague Vaclav Havel Airport | 1 transfer | |
 BA911 · BA862 | 6:20 AM Frankfurt am Main Airport | 13h25 | 7:45 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO384 · LO525 | 6:20 AM Frankfurt am Main Airport | 11h30 | 5:50 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO384 · LO529 | 6:20 AM Frankfurt am Main Airport | 14h25 | 8:45 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO384 · LO527 | 6:20 AM Frankfurt am Main Airport | 4h50 | 11:10 AM Prague Vaclav Havel Airport | 1 transfer | |
| LO384 · LO523 | 6:20 AM Frankfurt am Main Airport | 25h30 | 7:50 AM Prague Vaclav Havel Airport | 1 transfer | |
| BA911 · BA864 | 6:20 AM Frankfurt am Main Airport | 15h30 | 9:50 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO384 · LO521 | 6:20 AM Frankfurt am Main Airport | 9h55 | 4:15 PM Prague Vaclav Havel Airport | 1 transfer | |
| BA911 · BA858 | 6:20 AM Frankfurt am Main Airport | 10h50 | 5:10 PM Prague Vaclav Havel Airport | 1 transfer | |
| BA911 · BA854 | 6:20 AM Frankfurt am Main Airport | 6h15 | 12:35 PM Prague Vaclav Havel Airport | 1 transfer | |
| LH1392 | 7:45 AM Frankfurt am Main Airport | 1h05 | 8:50 AM Prague Vaclav Havel Airport | 0 transfersDirect | |
LH1973+ LH1690 | 8:10 AM Cologne Bonn Airport | 3h55 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
| LH98+LH1690 | 8:15 AM Frankfurt am Main Airport | 3h50 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
| LH1394 | 9:05 AM Frankfurt am Main Airport | 1h05 | 10:10 AM Prague Vaclav Havel Airport | 0 transfersDirect | |
 BA8762+BA858 | 9:15 AM Frankfurt am Main Airport | 7h55 | 5:10 PM Prague Vaclav Havel Airport | 1 transfer | |
 KL1816+KL1357 | 9:15 AM Frankfurt am Main Airport | 7h20 | 4:35 PM Prague Vaclav Havel Airport | 1 transfer | |
| KL1816+KL1361 | 9:15 AM Frankfurt am Main Airport | 12h05 | 9:20 PM Prague Vaclav Havel Airport | 1 transfer | |
| BA8762+BA864 | 9:15 AM Frankfurt am Main Airport | 12h35 | 9:50 PM Prague Vaclav Havel Airport | 1 transfer | |
| KL1816+KL1355 | 9:15 AM Frankfurt am Main Airport | 3h30 | 12:45 PM Prague Vaclav Havel Airport | 1 transfer | |
| BA8762+BA862 | 9:15 AM Frankfurt am Main Airport | 10h30 | 7:45 PM Prague Vaclav Havel Airport | 1 transfer | |
| KL1816+KL1359 | 9:15 AM Frankfurt am Main Airport | 9h20 | 6:35 PM Prague Vaclav Havel Airport | 1 transfer | |
| LH100+LH1690 | 9:15 AM Frankfurt am Main Airport | 2h50 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO382 · LO527 | 9:30 AM Frankfurt am Main Airport | 25h40 | 11:10 AM Prague Vaclav Havel Airport | 1 transfer | |
| LO382 · LO525 | 9:30 AM Frankfurt am Main Airport | 8h20 | 5:50 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO382 · LO523 | 9:30 AM Frankfurt am Main Airport | 22h20 | 7:50 AM Prague Vaclav Havel Airport | 1 transfer | |
| LO382 · LO529 | 9:30 AM Frankfurt am Main Airport | 11h15 | 8:45 PM Prague Vaclav Havel Airport | 1 transfer | |
| LO382 · LO521 | 9:30 AM Frankfurt am Main Airport | 6h45 | 4:15 PM Prague Vaclav Havel Airport | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Mainz to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mainz to Prague flights with Omio?
Lufthansa as well as Air Dolomiti, LOT Polish Airlines, Condor, Eurowings and more offer flights services from Mainz to Prague.
Omio is an official ticket reseller for all your travel options from Mainz to Prague.
Why book with Omio vs Lufthansa?
- Compare with other providers: On Omio, you can not only buy tickets for Lufthansa, but also compare tickets for the likes of Air Dolomiti, LOT Polish Airlines, Condor or Eurowings to find the best option for your trip from Mainz to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Lufthansa with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz to Prague.
Why book with Omio over Skyscanner, Trip or Kayak?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Air Dolomiti, LOT Polish Airlines, Condor or Eurowings to find the best option for your trip from Mainz to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz to Prague.
Airlines: Lufthansa, Air Dolomiti, LOT Polish Airlines, Condor, Eurowings from Mainz to PragueFind the best flights between Mainz to Prague with Omio's travel partners Lufthansa, Air Dolomiti, LOT Polish Airlines, Condor, Eurowings from $32 (€26). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Lufthansa
About
Lufthansa is Germany’s largest airline and one of the leading carriers in Europe, connecting travelers to destinations worldwide from its main hubs in Frankfurt and Munich. Its modern fleet offers a wide choice of travel experiences, from Economy Class with affordable fares and onboard entertainment to Premium Economy, Business Class, and First Class with extra comfort, fine dining, and exclusive lounge access.
Luggage & cancellation policy
Average Duration
1h 5m
Cheapest Price
$161 (€131)
Luggage included
1 carry-on bag (8 kg) and 1 personal item included in Economy Class
Additional luggage
Additional bags can be purchased, prices vary by route and fare type
Cancellation Policy
Refunds depend on fare type; most flexible fares offer full refund, basic fares are non-refundable
Pregnant on board
Lufthansa allows travel up to end of 36th week for single pregnancies, 32nd week for multiple pregnancies. Medical certificate required after 28th week
Unaccompagned minor
Unaccompanied minor service available for children aged 5-11 (mandatory) and 12-17 (optional). Service fee applies
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Lufthansa provides wheelchair service and special assistance for passengers with reduced mobility
Pets
Small dogs and cats allowed in cabin or cargo hold, fees apply. Service animals travel free of charge
Entertaiment on board
Air Dolomiti
About
Air Dolomiti is an Italian regional airline, a wholly-owned subsidiary of Lufthansa, and a member of Lufthansa Regional. Established in 1989, it began operations in 1991 with the goal of connecting smaller Italian cities to the rest of Europe.The airline primarily operates routes from various Italian destinations to and from Lufthansa's main hubs in Munich and Frankfurt, Germany. As of August 2025, Air Dolomiti serves 26 destinations in Italy and other European countries. Its fleet, which has evolved over the years to include Embraer 190 and 195 aircraft, is known for its focus on passenger comfort and Italian elegance in its inflight service.
Luggage & cancellation policy
Average Duration
1h 5m
Cheapest Price
$164 (€133)
Luggage included
1 carry-on bag (8kg, 55x40x23cm) and 1 personal item (40x30x10cm)
Additional luggage
Up to 23kg per piece, fees apply
Cancellation Policy
Free cancellation within 24 hours of booking if flight is more than 7 days away
Pregnant on board
Pregnant women can travel up to 36th week, medical certificate required after 28th week
Unaccompagned minor
Children aged 5-11 can travel unaccompanied with mandatory assistance service, must be booked in advance
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
Pets
Small pets in cabin allowed, max 8kg including carrier, must be booked in advance
Entertaiment on board
LOT Polish Airlines
About
LOT Polish Airlines, legally Polskie Linie Lotnicze LOT S.A., is the flag carrier of Poland and one of the world's oldest airlines, founded in 1928. It is a founding member of IATA and joined the Star Alliance in 2003. With its main hub at Warsaw Chopin Airport, LOT serves over 97 destinations across Europe, Asia, and North America with a fleet of 87 aircraft as of June 2025. The airline is recognized for operating one of Europe's youngest fleets and was the first European operator of the Boeing 787 Dreamliner.
Luggage & cancellation policy
Average Duration
13h 0m
Cheapest Price
$189 (€153)
Luggage included
1 carry-on bag (8kg, 55x40x23cm) and 1 personal item (40x35x12cm)
Additional luggage
Additional checked baggage can be purchased, with fees varying by route and timing of purchase
Cancellation Policy
Refunds depend on ticket type - flex tickets offer full refund, economy tickets are non-refundable but taxes can be reclaimed
Pregnant on board
Pregnant women can travel up to 32nd week without medical certificate, up to 36th week with medical certificate issued max 7 days before flight
Unaccompagned minor
Children aged 5-11 can travel as UM with mandatory assistance. Service must be booked at least 48h before departure
Amenities on board the airplane
Wifi
USB plugs
Accessibility
LOT provides assistance for passengers with reduced mobility, including wheelchair assistance and special seating arrangements
Pets
Small pets under 8kg allowed in cabin, larger animals in cargo hold. Must be booked in advance
Entertaiment on board
Condor
About
Condor Flugdienst GmbH, commonly known as Condor, is a German leisure airline established in 1955 and based in Neu-Isenburg, Hesse, with its main hub at Frankfurt Airport. It offers scheduled and charter flights, operating medium-haul routes to the Mediterranean Basin and the Canary Islands, as well as long-haul flights to destinations in Africa, Asia, North America, South America, and the Caribbean. Condor is recognized for its customer-centric services, providing various travel classes and in-flight amenities to enhance the passenger experience. The airline is also focused on sustainability, continually updating its fleet with more fuel-efficient aircraft.
Luggage & cancellation policy
Average Duration
1h 0m
Cheapest Price
$163 (€132)
Luggage included
1 piece of hand luggage (max 8kg) included in all fares
Additional luggage
Up to 23kg checked baggage can be added for a fee
Cancellation Policy
Free cancellation within 24h of booking if flight is more than 8 days away, otherwise fees apply based on fare type
Pregnant on board
Up to end of 36th week for single pregnancy, up to end of 32nd week for multiple pregnancy. Medical certificate required after 28th week
Unaccompagned minor
Available for children aged 5-11, must be booked at least 48h in advance, service fee applies
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Wheelchair assistance available, must be requested at least 48h before departure
Pets
Small pets in cabin (max 6kg including carrier), must be booked in advance, limited spots
Entertaiment on board
Eurowings
About
Eurowings is a German low-cost airline that offers affordable flights across Europe and to select long-haul destinations. As part of the Lufthansa Group, Eurowings connects major European cities as well as holiday destinations with a modern fleet. Passengers can choose from different fare options ranging from basic economy with great value to more flexible tickets that include extra comfort, priority boarding, and additional services. With onboard amenities such as snacks, drinks, and WiFi available on many routes, Eurowings is a convenient choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
1h 20m
Cheapest Price
$99 (€80)
Luggage included
1 small bag (40x30x20cm) included
Additional luggage
Additional cabin bag (55x40x23cm) and checked baggage available for purchase
Cancellation Policy
Free cancellation within 24h of booking if flight is more than 7 days away. After that, cancellation fees apply based on fare type
Pregnant on board
Pregnant women can fly until the end of 36th week (32nd week for multiple pregnancies). Medical certificate required after 28th week
Unaccompagned minor
Children aged 5-11 can travel as UM with mandatory assistance. Ages 12-17 optional assistance. Service must be booked in advance
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
Pets
Small pets in cabin, max 8kg including carrier. Must be booked in advance
Entertaiment on board
FAQs: Mainz to Prague Flight
Find answers to the most common questions about traveling from Mainz to Prague by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Mainz to Prague can start from as little as $99 (€80) when you book in advance. The average flight ticket price for Mainz to Prague is $202 (€163) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Mainz to Prague is 1h 0m to travel the 272 miles (439 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Mainz to Prague leaves at 5:15 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Mainz to Prague leaves at 10:15 PM.
Yes, there are 9 direct flights a day from Mainz to Prague with Lufthansa, Air Dolomiti, Condor. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Mainz to Prague, you can count on Lufthansa, Air Dolomiti, LOT Polish Airlines, Condor, Eurowings for the best way to get you to Prague. You can also check all possible airlines who offer a service between Mainz and Prague and compare the amenities they offer before buying a plane ticket.
Flights from Mainz to Prague generally leave from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.Frankfurt am Main Airport is 6 miles (10 km) away from Mainz city centre and Prague Vaclav Havel Airport is 6 miles (11 km) from Prague city centre.
The cheapest month for a flight from Mainz to Prague is June.
It's helpful to compare your options as there are 3 ways to travel between Mainz and Prague including taking a bus, train, and flight.
Since both Mainz and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
There is no time difference between Mainz and Prague.
The best events to attend in Prague include:
- Prague Spring International Music Festival, a prestigious classical music festival featuring renowned orchestras and soloists
- Prague Food Festival, a culinary event showcasing the best of Czech cuisine and local chefs
- Signal Festival, an annual light art festival transforming the city with stunning light installations
- Christmas Markets, traditional markets offering festive food, crafts, and holiday cheer throughout the city.
The best holidays to experience in Prague include:
- Easter, beautiful spring weather and traditional celebrations
- Labour Day, local festivities and a lively atmosphere in early May
- Czech Statehood Day, cultural events and parades in September
- Independence Day, patriotic celebrations and community gatherings in October.
The best season to visit Prague is Spring or Fall. The best weather to explore Prague is during April-June or September-October.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
popular airports
Popular airports from Mainz to Prague
Mainz
Prague
Amenities at airport
Wifi
Shopping
Parking
ATM
Taxis
Accessibility
WC
Shower
Lounge
Lost and Found Officeinformation
Distance to city center
11 km
Car connection
D7, Exit 2Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops in Terminals 1 and 2, duty-free, fashion, electronics.
Parking
- Parking available, short-term parking from approximately 2.5€ (60 CZK) per hour.
Taxis
- Available outside the terminal.
Accessibility
- Ramps, assistance.
WC
- Available throughout the airport.
Shower
- Yes
Lounge
- Lounges available, Mastercard Lounge, Erste Premier Lounge.
Lost and Found Office
- Located in Terminal 1, open daily.
Public transit options for Prague Vaclav Havel Airport
- Bus: 119, 100
- Metro: A (via bus 119)
- Train: NA
More options for your journey from Mainz to Prague
Here are some other resources that might have the information you need
Most popular flights to and from Prague and Mainz
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