Journey information
Overview: Mainz to Prague flight
Flights from Mainz to Prague depart on average 73 times per day, taking around 1h 29m. Cheap flight tickets for this journey start at $100 (€80) but you can travel from only $32 (€26) by bus.
There are 9 flights per day. The earliest flight runs at 05:15, the last at 22:15. The fastest flight covers the 272 miles (439 km) distance in 1h 0m. June is the cheapest month to fly.
Distance 272 miles (439 km) |
Average flight duration 1h 29m |
Cheapest ticket price $100 (€80) |
Flights per day 73 |
Direct flights 9 |
Fastest flight 1h 0m |
First flight 5:15 AM |
Last flight 10:15 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 35 days |
The cheapest and fastest flights from Mainz to Prague
Cheapest price
$176
Average price
$191
Fastest journey
1 h
Average duration
1 h 56 m
Flights per day
5
Distance
439 km
The best way to find a cheap flight ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz to Prague will cost around $191 if you buy it on the day, but the cheapest tickets can be found for only $176.
Of the 5 flights that leave Mainz for Prague onThu, May 07, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 07 the direct flights cover the 439 km distance in an average of 1 h 56 m but if you time it right, some flights will get you there in just 1 h .
On Thu, May 07 the longest flights will take 3 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:40 PM2h45Mainz9:25 PMPrague$1761One-way0 transfers
5:30 PM3h50Mainz9:20 PMPrague$1761One-way0 transfers
6:50 PM13h00Mainz7:50 AMPrague$1921One-way0 transfers
7:10 PM1h00Mainz8:10 PMPrague$1971One-way0 transfers
7:40 AM1h05Mainz8:45 AMPrague$2161One-way0 transfers
1:15 PM1h00Mainz2:15 PMPrague$2301One-way0 transfers
7:10 PM1h00Mainz8:10 PMPrague$1971One-way0 transfers
7:40 AM1h05Mainz8:45 AMPrague$2161One-way0 transfers
6:40 PM2h45Mainz9:25 PMPrague$1761One-way0 transfers
5:30 PM3h50Mainz9:20 PMPrague$1761One-way0 transfers
Travel Information
Compare bus, train, and flight for Mainz to Prague
Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $100.
Distance: 272 miles (439 km)
Compare flight with
| Flight | Most popular Train | Bus |
|---|---|---|
$205 Average price | $109 Average price | $48 Average price Cheapest |
4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 9h 5m Average total duration 8h 35m Onboard + 30m Additional time* | 7h 40m Average total duration 7h 10m Onboard + 30m Additional time* |
1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Prague flight times
The table below shows live departures for Mainz to Prague flights for today, Wednesday, May 6. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
DE4407 | 3:00 PM Frankfurt am Main Airport | 1h00 | 4:00 PM Prague Vaclav Havel Airport | 0 transfersDirect | |
LO4896+ LO527 | 4:45 PM Frankfurt am Main Airport | 19h20 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
LO4896+ LO523 | 4:45 PM Frankfurt am Main Airport | 16h30 | 9:15 AM Prague Vaclav Havel Airport | 1 transfer | |
LO378 · LO523 | 5:30 PM Frankfurt am Main Airport | 15h45 | 9:15 AM Prague Vaclav Havel Airport | 1 transfer | |
LO378 · LO525 | 5:30 PM Frankfurt am Main Airport | 25h30 | 7:00 PM Prague Vaclav Havel Airport | 1 transfer | |
LO378 · LO527 | 5:30 PM Frankfurt am Main Airport | 18h35 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
KL1822+ KL1353 | 6:40 PM Frankfurt am Main Airport | 15h50 | 10:30 AM Prague Vaclav Havel Airport | 1 transfer | |
KL1822+ KL1351 | 6:40 PM Frankfurt am Main Airport | 13h40 | 8:20 AM Prague Vaclav Havel Airport | 1 transfer | |
KL1822+ KL1361 | 6:40 PM Frankfurt am Main Airport | 3h55 | 10:35 PM Prague Vaclav Havel Airport | 1 transfer | |
DE4411 | 7:40 PM Frankfurt am Main Airport | 1h00 | 8:40 PM Prague Vaclav Havel Airport | 0 transfersDirect | |
LO380 · LO525 | 7:50 PM Frankfurt am Main Airport | 23h10 | 7:00 PM Prague Vaclav Havel Airport | 1 transfer | |
LO380 · LO527 | 7:50 PM Frankfurt am Main Airport | 16h15 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
LO380 · LO529 | 7:50 PM Frankfurt am Main Airport | 25h50 | 9:40 PM Prague Vaclav Havel Airport | 1 transfer | |
LO380 · LO523 | 7:50 PM Frankfurt am Main Airport | 13h25 | 9:15 AM Prague Vaclav Havel Airport | 1 transfer | |
LO4894+ LO525 | 8:40 PM Frankfurt am Main Airport | 22h20 | 7:00 PM Prague Vaclav Havel Airport | 1 transfer | |
LO4894+ LO527 | 8:40 PM Frankfurt am Main Airport | 15h25 | 12:05 PM Prague Vaclav Havel Airport | 1 transfer | |
LO4894+ LO523 | 8:40 PM Frankfurt am Main Airport | 12h35 | 9:15 AM Prague Vaclav Havel Airport | 1 transfer | |
LO4894+ LO529 | 8:40 PM Frankfurt am Main Airport | 25h00 | 9:40 PM Prague Vaclav Havel Airport | 1 transfer | |
BA909 · BA850 | 8:50 PM Frankfurt am Main Airport | 12h20 | 9:10 AM Prague Vaclav Havel Airport | 1 transfer | |
| Thursday, May 7 | |||||
![]() | 7:40 AM Mainz | 1h05 | 8:45 AM Prague | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Mainz to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
May 08
May 09
May 10
May 11
May 12
May 13
Why should you book Mainz to Prague flights with Omio?
Why book with Omio vs Lufthansa?
- Compare with other providers: On Omio, you can not only buy tickets for Lufthansa, but also compare tickets for the likes of Air Dolomiti, Lot Polish Airlines, Condor Flugdienst or Eurowings to find the best option for your trip from Mainz to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Lufthansa with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz to Prague.
Why book with Omio over Skyscanner, Trip or Kayak?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Air Dolomiti, Lot Polish Airlines, Condor Flugdienst or Eurowings to find the best option for your trip from Mainz to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz to Prague.
Airlines: Lufthansa, Air Dolomiti, Lot Polish Airlines, Condor Flugdienst, Eurowings from Mainz to PragueFind the best flights between Mainz to Prague with Omio's travel partners Lufthansa, Air Dolomiti, Lot Polish Airlines, Condor Flugdienst, Eurowings from $32 (€26). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Lufthansa
Air Dolomiti
Lot Polish Airlines
Condor Flugdienst
Eurowings
FAQs: Mainz to Prague Flight
Find answers to the most common questions about traveling from Mainz to Prague by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Prague Spring International Music Festival, a prestigious classical music festival featuring renowned orchestras and soloists
- Prague Food Festival, a culinary event showcasing the best of Czech cuisine and local chefs
- Signal Festival, an annual light art festival transforming the city with stunning light installations
- Christmas Markets, traditional markets offering festive food, crafts, and holiday cheer throughout the city.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Easter, beautiful spring weather and traditional celebrations
- Labour Day, local festivities and a lively atmosphere in early May
- Czech Statehood Day, cultural events and parades in September
- Independence Day, patriotic celebrations and community gatherings in October.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
popular airports
Popular airports from Mainz to Prague
- Free Wi-Fi available throughout the airport.
- Shops in Terminals 1 and 2, duty-free, fashion, electronics.
- Parking available, short-term parking from approximately 2.5€ (60 CZK) per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available, Mastercard Lounge, Erste Premier Lounge.
- Located in Terminal 1, open daily.
- Bus: 119, 100
- Metro: A (via bus 119)
- Train: NA
More options for your journey from Mainz to Prague
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