The cheapest and fastest trains from Mainz to Milan
Cheapest price
$289
Average price
$289
Fastest journey
14 h 33 m
Average duration
14 h 33 m
Trains per day
1
Distance
507 km
The best way to find a cheap train ticket from Mainz to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz to Milan will cost around $289 if you buy it on the day, but the cheapest tickets can be found for only $289.
It's difficult to get from Mainz to Milan without transferring at least 3 times.


Travel Information
Compare train, bus, and flight for Mainz to Milan
Omio recommends booking the flight as it is the most popular option from Mainz to Milan among Omio's users. If you are prioritising price take the bus with prices starting from €29. For those with little time consider booking a flight which can get you there in 1h 18m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €29, and a train costs an average of €137.
Distance: 315 miles (507 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€137 Average price | €56 Average price | €54 Average price Cheapest |
8h 39m Average total duration 8h 9m Onboard + 30m Additional time* | 4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* | 12h 45m Average total duration 12h 15m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 1.5 - 3.0kg CO2 emissions | 0.5 - 1.3kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Milan train times
The table below shows live departures for Mainz to Milan trains for today, Friday, December 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:54 PM Mainz | 12h56 | 11:50 AM Milan | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz to Milan by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Dec 12
Why should you book Mainz to Milan trains with Omio?
Deutsche Bahn as well as Trenitalia and Süwex offer trains services from Mainz to Milan. Omio is an official ticket reseller for all your travel options from Mainz to Milan.
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Trenitalia and Süwex to find the best option for your trip from Mainz to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mainz to Milan.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn tickets can be bought on Deutsche Bahn's website or third party sellers, Omio allows you to compare with the likes of Trenitalia and Süwex to help you choose the right option for your journey from Mainz to Milan.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mainz to Milan.
Journey information
Overview: Train from Mainz to Milan
Trains from Mainz to Milan run on average 1 times per day, taking around 8h 9m. Cheap train tickets for this journey start at $170 (€137) but you can travel from only $31 (€25) by flight.
The earliest train runs at 04:10, the last at 18:20. The fastest train covers the 315 miles (507 km) distance in 8h 28m.
Distance 315 miles (507 km) |
Average train duration 8h 9m |
Cheapest ticket price $170 (€137) |
Trains per day 1 |
Fastest train 8h 28m |
First train 04:10 |
Last train 18:20 |
Train companies: Deutsche Bahn, Trenitalia, Süwex from Mainz to Milan trainsDeutsche Bahn, Trenitalia, Süwex trains will get you between Mainz and Milan from $31 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Trenitalia
Süwex
FAQs: Trains from Mainz to Milan
Find answers to the most common questions about traveling from Mainz to Milan by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mainz to Milan
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Mainz
More options for your journey from Mainz to Milan
Here are some other resources that might have the information you need



