- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Cheapest price
$0.00
Average price
$169
Fastest journey
7 h 59 m
Average duration
8 h 5 m
Trains per day
12
Distance
507 km
The best way to find a cheap train ticket from Mainz to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Mainz to Milan without transferring at least 4 times.
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Omio recommends booking the bus as it is the most popular option from Mainz to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $40. For those with little time consider booking a flight which can get you there in 1h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $40, and a train costs an average of $217.
Distance: 315 miles (507 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$221 Average price | $64 Average price Cheapest | $106 Average price | $199 Average price (fuel + tolls) |
8h 34m Average total duration 8h 4m Onboard + 30m Additional time* | 12h 42m Average total duration 12h 12m Onboard + 30m Additional time* | 4h 19m Average total duration Fastest 1h 19m Onboard + 3h 0m Additional time* | 7h 40m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mainz to Milan:
A bus is $41 (€34) less than a flight for this route with tickets for a flight from Mainz to Milan costing on average $106 (€87).
A bus is $156 (€129) less than a train for this route with tickets for a train from Mainz to Milan costing on average $221 (€182).
Other travel options to Milan take longer:
Train takes on average 8h 4m.
Bus takes on average 12h 12m.
Tickets start at around $221 (€182) compared to roughly $199 (€164) in fuel and tolls — a saving of about $-21.31 (€-17.54). The journey takes 8h 4m versus 7h 40m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Mainz to Milan trains for tomorrow, Tuesday, July 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:18 AM Mainz | 7h59 | 1:17 PM Milan | 4 transfers | |
![]() | 5:56 AM Mainz | 8h21 | 2:17 PM Milan | 4 transfers | |
![]() | 7:00 AM Mainz | 8h17 | 3:17 PM Milan | 4 transfers | |
![]() | 7:57 AM Mainz | 8h20 | 4:17 PM Milan | 4 transfers | |
![]() | 9:13 AM Mainz | 8h04 | 5:17 PM Milan | 4 transfers | |
![]() | 9:57 AM Mainz | 8h20 | 6:17 PM Milan | 4 transfers | |
![]() | 11:17 AM Mainz | 8h00 | 7:17 PM Milan | 4 transfers | |
![]() | 11:57 AM Mainz | 8h20 | 8:17 PM Milan | 4 transfers | |
![]() | 1:13 PM Mainz | 8h04 | 9:17 PM Milan | 4 transfers | |
![]() | 1:57 PM Mainz | 8h20 | 10:17 PM Milan | 4 transfers | |
![]() | 5:13 PM Mainz | 14h04 | 7:17 AM Milan | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Mainz to Milan run on average 1 times per day, taking around 8h 4m. Cheap train tickets for this journey start at $217 (€178) but you can travel from only $21 (€17) by flight.
The earliest train runs at 04:10, the last at 17:35. The fastest train covers the 315 miles (507 km) distance in 8h 28m.
Distance 315 miles (507 km) |
Average train duration 8h 4m |
Cheapest ticket price $217 (€178) |
Trains per day 1 |
Fastest train 8h 28m |
First train 4:10 AM |
Last train 5:35 PM |
Cheapest Month Nov |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 14 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Milan Centrale -> Piazza del Duomo
Find answers to the most common questions about traveling from Mainz to Milan by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Mainz to Milan trains use the Mainz Hbf to Milano Centrale station pair. Use this guide to compare Mainz and Milan train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Mainz Hbf is 2 km from Mainz city centre. Public transport options include:
Mainz Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Mangal, Asia Wok, Bistrorante Midi, McDonald's
Wi-Fi is available at Mainz Hbf. ATMs are available at Mainz Hbf.
Ticket office support is available at Mainz Hbf. Information desks are available at Mainz Hbf.
Luggage storage is available at Mainz Hbf. Lost and found is available at the station.
Available at Mainz Hbf: Parking, Taxis, WC.
Available at Mainz Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mainz Hbf.
Nearby hotels include Advena Europa Hotel, GuestHouse Mainz, Terminus, Hotel Moguntia.
Milano Centrale is 2 km from Milan city centre. Public transport options include:
Milano Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Venchi, Panzera Coffee, Burger King, Bar Motta, Caffè Napoli, VyTA Boulangerie, Spontini, Starbucks, Dispensa Emilia, McDonald's, & many more
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 05:50 - 22:20. Information desks are located next to the ticket office on the ground floor in the shopping gallery.
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Available at Milano Centrale: Parking, Taxis, WC.
Available at Milano Centrale: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Milano Centrale: Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Nearby hotels include Glam Hotel Milano, NYX MIlan, iQ Hotel Milano.
Here are some other resources that might have the information you need