- Must visit
Gutenberg Museum
World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.
Cheapest price
$54
Average price
$134
Fastest journey
8 h 23 m
Average duration
8 h 37 m
Trains per day
7
Distance
439 km
The best way to find a cheap train ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Mainz will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $54.
It's difficult to get from Prague to Mainz without transferring at least 2 times.
EX 358 · 3568 · ICE 624 · 29528
EX 358 · 3570 · ICE 26
RJ 178 · IC 2440 · ICE 2555 · 29262
RJ 382 · IC 2442 · ICE 5327 · 4264
RJ 382 · IC 2442 · ICE 5327 · 4531
EX 358 · 3568 · ICE 624 · 29528
EC 358 · R 3568 · ICE 624 · RB 29528
EX 358 · 3570 · ICE 26
EC 358 · R 3568 · ICE 26
RJ 382 · IC 2442 · ICE 5327 · 4531Omio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 15m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $86.
Distance: 272 miles (439 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$135 Average price | $43 Average price Cheapest | $176 Average price | $117 Average price (fuel + tolls) |
8h 2m Average total duration 7h 32m Onboard + 30m Additional time* | 7h 32m Average total duration 7h 2m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 1h 15m Onboard + 3h 0m Additional time* | 5h 11m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Mainz:
A bus is $92 (€76) less than a train for this route with tickets for a train from Prague to Mainz costing on average $135 (€111).
A bus is $133 (€109) less than a flight for this route with tickets for a flight from Prague to Mainz costing on average $176 (€144).
Other travel options to Mainz take longer:
Bus takes on average 7h 2m.
Train takes on average 7h 32m.
Tickets start at around $135 (€111) compared to roughly $117 (€96) in fuel and tolls — a saving of about $-17.35 (€-14.25). The journey takes 7h 32m versus 5h 11m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Prague to Mainz trains for today, Monday, July 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:47 PM Prague | 15h02 | 9:49 AM Mainz | 0 transfersDirect | |
| Tuesday, July 21 | |||||
RJ 178 · IC 2440 · ICE 2555 · 29262 | On time 8:31 AM Prague hlavní nádraží | 8h59 | 5:30 PM Mainz Hbf | 3 transfers | |
EC 358 · R 3568 · ICE 624 · RB 29528 | 9:35 AM Prague hlavní nádraží | 8h23 | 5:58 PM Mainz Hbf | 3 transfers | |
EC 358 · R 3568 · ICE 26 | On time 9:35 AM Prague hlavní nádraží | 8h43 | 6:18 PM Mainz Hbf | 2 transfers | |
EX 358 · 3570 · ICE 26 | On time 9:35 AM Prague hlavní nádraží | 8h43 | 6:18 PM Mainz Hbf | 2 transfers | |
EX 358 · 3568 · ICE 624 · 29528 | On time 9:35 AM Prague hlavní nádraží | 8h23 | 5:58 PM Mainz Hbf | 3 transfers | |
RJ 382 · IC 2442 · ICE 5327 · 4264 | On time 10:31 AM Prague hlavní nádraží | 9h18 | 7:49 PM Mainz Hbf | 3 transfers | |
RJ 382 · IC 2442 · ICE 5327 · 4531 | On time 10:31 AM Prague hlavní nádraží | 8h54 | 7:25 PM Mainz Hbf | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Prague to Mainz run on average 7 times per day, taking around 7h 32m. Cheap train tickets for this journey start at $41 (€34) but you can travel from only $32 (€26) by bus.
The earliest train runs at 00:02, the last at 23:53. The fastest train covers the 272 miles (439 km) distance in 7h 43m.
Distance 272 miles (439 km) |
Average train duration 7h 32m |
Cheapest ticket price $41 (€34) |
Trains per day 7 |
Fastest train 7h 43m |
First train 12:02 AM |
Last train 11:53 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 49 days |
Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.
World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.
State museum with art, archaeology, and Roman finds, spanning ancient artifacts to paintings and decorative arts.
Museum on Roman Mainz featuring military, daily life, and stone monuments from the city’s ancient past.
Main market square beside the cathedral, lively with historic façades, weekly markets, and a classic old-town atmosphere.
Picturesque old-town lane lined with half-timbered houses, shops, and a timeless atmosphere loved by local walkers.
Broad Rhine promenade ideal for walks, river views, events, and seeing Mainz’s waterside landmarks in one stretch.
Spundekäs is a creamy cheese spread with paprika, served with pretzels. It is a Rheinhessen wine tavern classic and a staple snack in Mainz.
Weck, Worscht un Woi means bread roll, sausage and wine. It is a simple regional trio closely tied to Mainz tavern culture and local wine drinking.
Handkäs mit Musik is a sour milk cheese marinated with onions and vinegar. It is a beloved Hessian and Rhine-Main tavern dish often enjoyed with bread.
Refined Michelin-starred dining with seasonal tasting menus and polished service in an elegant setting.
Traditional Mainz wine tavern known for regional dishes, local wines and a historic atmosphere near the old town.
Classic brewery restaurant serving Mainz specialties and house beer in a lively, long-established setting.
Moderate for Germany: hotels and dining are mid-priced, while local transit is reasonable for city stays and day trips.
Service is usually included, but rounding up or adding 5-10% is customary. Round up for cafes and taxis, and hand the tip directly when paying.
Official public transport app
Mainz Hbf -> Schillerplatz, Mainz
Find answers to the most common questions about traveling from Prague to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

Most Prague to Mainz trains use the Praha hlavní nádraží to Mainz Hbf station pair, with some services arriving at Mainz Römisches Theater. Use this guide to compare Prague and Mainz train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Mainz Hbf is 2 km from Mainz city centre. Public transport options include:
Mainz Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Mangal, Asia Wok, Bistrorante Midi, McDonald's
Wi-Fi is available at Mainz Hbf. ATMs are available at Mainz Hbf.
Ticket office support is available at Mainz Hbf. Information desks are available at Mainz Hbf.
Luggage storage is available at Mainz Hbf. Lost and found is available at the station.
Available at Mainz Hbf: Parking, Taxis, WC.
Available at Mainz Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mainz Hbf.
Nearby hotels include Advena Europa Hotel, GuestHouse Mainz, Terminus, Hotel Moguntia.
Mainz Römisches Theater is 1 km from Mainz city centre. Public transport options include:
Mainz Römisches Theater has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: McDonald's, Cafe Extrablatt, Hans im Glück, The Big Easy
Wi-Fi is available at Mainz Römisches Theater. ATMs are available at Mainz Römisches Theater.
Ticket office support is available at Mainz Römisches Theater. Information desks are available at Mainz Römisches Theater.
Luggage storage is available at Mainz Römisches Theater. Lost and found is available at the station.
Available at Mainz Römisches Theater: Parking, Taxis, WC.
Available at Mainz Römisches Theater: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mainz Römisches Theater.
Nearby hotels include Hyatt Regency Mainz, Favorite Parkhotel, Ibis Hotel Mainz City, Hof Ehrenfels.
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