The cheapest and fastest trains from Prague to Mainz
Cheapest price
$45
Average price
$76
Fastest journey
7 h 43 m
Average duration
8 h 9 m
Trains per day
3
Distance
439 km
The best way to find a cheap train ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Mainz will cost around $76 if you buy it on the day, but the cheapest tickets can be found for only $45.
Of the 3 trains that leave Prague for Mainz on Tue, Jan 20, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jan 20 the direct trains cover the 439 km distance in an average of 8 h 9 m but if you time it right, some trains will get you there in just 7 h 43 m .
On Tue, Jan 20 the slowest trains will take 8 h 23 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus, train, and flight for Prague to Mainz
Omio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 16m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a flight costs an average of €51.
Distance: 272 miles (439 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€85 Average price | €37 Average price Cheapest | €124 Average price |
8h 11m Average total duration 7h 41m Onboard + 30m Additional time* | 7h 29m Average total duration 6h 59m Onboard + 30m Additional time* | 4h 16m Average total duration Fastest 1h 16m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Mainz train times
The table below shows live departures for Prague to Mainz trains for today, Monday, January 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
RJ 178 · ICE 1558 · 4262 | On time 7:31 AM Prague hlavní nádraží | 9h10 | 4:41 PM Mainz Hbf | 2 transfers | |
RJ 178 · IC 2440 · ICE 599 · 20966 | On time 7:31 AM Prague hlavní nádraží | 8h07 | 3:38 PM Mainz Hbf | 3 transfers | |
EX 358 · ICE 26 · 20968 | On time 8:35 AM Prague hlavní nádraží | 9h03 | 5:38 PM Mainz Hbf | 2 transfers | |
EX 358 · 3568 · ICE 624 · 15594 | On time 8:35 AM Prague hlavní nádraží | 8h52 | 5:27 PM Mainz Hbf | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Mainz by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 20
Jan 21
Jan 22
Jan 23
Jan 24
Jan 25
Jan 26
Why should you book Prague to Mainz trains with Omio?
Deutsche Bahn (ICE,RE,EC,IC,RB) operates all train services from Prague to Mainz. Omio is the only official third party seller for Deutsche Bahn (ICE,RE,EC,IC,RB) tickets.
Why book with Omio vs Deutsche Bahn (ICE,RE,EC,IC,RB)?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (ICE,RE,EC,IC,RB) with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Prague to Mainz.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Deutsche Bahn (ICE,RE,EC,IC,RB) tickets can only be bought on Omio or Deutsche Bahn (ICE,RE,EC,IC,RB)'s website as Omio is the only official third party seller for Deutsche Bahn (ICE,RE,EC,IC,RB) tickets. Trainline, RailEurope, and Rail.Ninja do not sell Deutsche Bahn (ICE,RE,EC,IC,RB) tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Prague to Mainz.
Journey information
Overview: Train from Prague to Mainz
Train Ticket Prices
- Budget Options: Train tickets from Prague to Mainz start from as low as $35 (€28) if booked well in advance.
- Standard Fares: Typically, trains cost $105 (€85) depending on the train type and class.
Journey Duration & Frequency
- On average there are 8 daily trains from Prague to Mainz with 0 direct service.
- The fastest trains can take as little as 7h 43m but the average duration is 7h 41m
Train Operators
- Travel from Prague to Mainz with Deutsche Bahn
- The most booked train company for this route on Omio is Deutsche Bahn.
Stations & Schedule
- Most trains depart from Prague hlavní nádraží and arrive in Mainz Hbf
- First train typically departs at 12:02 AM and the last at 11:45 PM
Distance 272 miles (439 km) |
Average train duration 7h 41m |
Cheapest ticket price $35 (€28) |
Trains per day 8 |
Fastest train 7h 43m |
First train 00:02 |
Last train 23:45 |
Train companies: Deutsche Bahn from Prague to Mainz trainsDeutsche Bahn trains will get you between Prague and Mainz from $31 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Trains from Prague to Mainz
Find answers to the most common questions about traveling from Prague to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Prague to Mainz
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
More options for your journey from Prague to Mainz
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