Prague to Mainz train with Deutsche Bahn (ICE,IC,EC)

Tue, Oct 20
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České dráhy
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2,000+ travel companies
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The cheapest and fastest trains from Prague to Mainz

Showing times, prices and bookable tickets for Oct 20

Cheapest price on Oct 20

$76

Average ticket price on Oct 20

$109

Fastest journey on Oct 20

8 h 18 m

Average journey duration on Oct 20

8 h 35 m

Trains on Oct 20

5

Distance

439 km

Cheap tickets

The best way to find a cheap train ticket from Prague to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Prague to Mainz will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $76.

Fast trains

It's difficult to get from Prague to Mainz without transferring at least 2 times.

  • Deutsche BahnEX 358 · Bus RE25 · 3568 · ICE 624
    9:35 AM8h20
    Prague hlavní nádraží
    5:55 PMMainz Hbf
    $761One-way
    4 transfers
  • Deutsche BahnEX 358 · Bus RE25 · 3570 · ICE 26
    9:35 AM8h43
    Prague hlavní nádraží
    6:18 PMMainz Hbf
    $931One-way
    3 transfers
  • Deutsche BahnRJ 178 · ICE 1558 · S8
    8:31 AM8h54
    Prague hlavní nádraží
    5:25 PMMainz Hbf
    $1141One-way
    2 transfers
  • Deutsche BahnR 692 · Os 28005 · S1 · ICE 1558
    8:47 AM8h38
    Prague hlavní nádraží
    5:25 PMMainz Hbf
    $1141One-way
    4 transfers
  • Deutsche BahnRJ 178 · IC 2440 · ICE 599 · 29526
    8:31 AM8h18
    Prague hlavní nádraží
    4:49 PMMainz Hbf
    $1471One-way
    3 transfers

Journey information

Overview: Train from Prague to Mainz

CzechiaCzechia
GermanyGermany
Icon of train

Trains from Prague to Mainz run on average 7 times per day, taking around 7h 38m. Cheap train tickets for this journey start at $40 but you can travel from only $33 by bus.

The earliest train runs at 00:02, the last at 23:53. The fastest train covers the 272 miles (439 km) distance in 6h 52m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $33
Distance
272 miles (439 km)
Average train duration
7h 38m
Cheapest ticket price
$40
Trains per day
7
Fastest train
6h 52m
First train
12:02 AM
Last train
11:53 PM
Cheapest Month
Aug
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Oct - Dec
Busiest Day
Sun
Least Busy Day
Fri
Best time to book
49 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $33

Live departures

Prague to Mainz train times

The table below shows live departures for Prague to Mainz trains for today, Monday, October 19. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Deutsche BahnEX 354 · Bus RE25 · 3578 · ICE 22
On time
1:35 PM Prague hlavní nádraží
8h43
10:18 PM Mainz Hbf
3 transfers
Deutsche BahnEX 354 · Bus RE25 · 3576 · ICE 5261:35 PM Prague hlavní nádraží
8h20
9:55 PM Mainz Hbf4 transfers
Deutsche BahnR 686 · BUS 10174 · ICE 1552 · S81:47 PM Prague hlavní nádraží
9h38
11:25 PM Mainz Hbf3 transfers
Deutsche BahnRJ 174 · BUS 10174 · ICE 1552 · S82:41 PM Prague-Holešovice
8h44
11:25 PM Mainz Hbf3 transfers
Tuesday, October 20
Deutsche BahnRJ 178 · ICE 1558 · S8
On time
8:31 AM Prague hlavní nádraží
8h54
5:25 PM Mainz Hbf
2 transfers
Deutsche BahnRJ 178 · IC 2440 · ICE 599 · 29526
On time
8:31 AM Prague hlavní nádraží
8h18
4:49 PM Mainz Hbf
3 transfers
Deutsche BahnR 692 · Os 28005 · S1 · ICE 15588:47 AM Prague hlavní nádraží
8h38
5:25 PM Mainz Hbf4 transfers
Deutsche BahnEX 358 · Bus RE25 · 3568 · ICE 6249:35 AM Prague hlavní nádraží
8h20
5:55 PM Mainz Hbf4 transfers
Deutsche BahnEX 358 · Bus RE25 · 3570 · ICE 26
On time
9:35 AM Prague hlavní nádraží
8h43
6:18 PM Mainz Hbf
3 transfers

This is the last train of the day.

Find all the dates and times for this journey

Why should you book Prague to Mainz trains with Omio?

Deutsche Bahn as well as České dráhy offer trains services from Prague to Mainz.
Omio is an official ticket reseller for all your travel options from Prague to Mainz.

Why book with Omio vs Deutsche Bahn?

  • Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy to find the best option for your trip from Prague to Mainz.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Mainz.

Why book with Omio over Trainline, Wanderu or Raileurope?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Mainz.

Train companies: Deutsche Bahn, České dráhy from Prague to Mainz trainsDeutsche Bahn, České dráhy trains will get you between Prague and Mainz from $33. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Deutsche Bahn Duration
6h 52m
Cheapest Deutsche Bahn Price
$40
Deutsche Bahn frequency
5 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

České dráhy

About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average České dráhy Duration
7h 2m
Cheapest České dráhy Price
$71
České dráhy frequency
3 a day
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the train
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.

Complete guide to Mainz

Things to do in Mainz

Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.

  • Must visit

Gutenberg Museum

World-class museum dedicated to Johannes Gutenberg, showcasing early printing, rare books, and working press demonstrations.

  • Must visit

Landesmuseum Mainz

State museum with art, archaeology, and Roman finds, spanning ancient artifacts to paintings and decorative arts.

  • Recommended

Museum of Ancient Seafaring

Museum on Roman Mainz featuring military, daily life, and stone monuments from the city’s ancient past.

Euro (€)

Moderate for Germany: hotels and dining are mid-priced, while local transit is reasonable for city stays and day trips.

Average meal costs

Budget
€8-12 for fast food or kebab.
Mid-range
€18-30 per person for a restaurant meal.
Fine dining
€60+ per person for upscale dining.
Coffee
€2.80-4.20 for coffee or cappuccino.

Tipping culture

Service is usually included, but rounding up or adding 5-10% is customary. Round up for cafes and taxis, and hand the tip directly when paying.

FAQs: Trains from Prague to Mainz

Find answers to the most common questions about traveling from Prague to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Prague to Mainz can vary. The cheapest ticket starts at $40, while the average price is around $142.
The train from Prague to Mainz takes 6h 52m and runs 7 per day.
The distance by train from Prague to Mainz is 272 miles (439 km).
The first train from Prague to Mainz leaves at 12:02 AM.
The last train from Prague to Mainz leaves at 11:53 PM.
There is no direct train service currently available from Prague to Mainz.
Yes, there is a night train from Prague to Mainz.
The train station in Prague that goes to Mainz is Prague hlavní nádraží, which connects to Mainz Hbf.
The train journey from Prague to Mainz offers scenic views, including picturesque landscapes of the Czech countryside, Bohemian Forest, and river valleys as you travel through Germany.
Yes, you can take the train from Prague to Mainz.
Popular day trips by train from Mainz include Cologne, Stuttgart, Heidelberg, Frankfurt am Main, Mannheim.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
In Mainz, travelers should be cautious of pickpocketing, especially in crowded areas like train stations and popular tourist spots. Scams involving overcharging in taxis or at markets can occur, so always agree on prices beforehand. It's advisable to stay vigilant in busy places and keep valuables secure to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Prague to Mainz

Most Prague to Mainz trains use the Praha hlavní nádraží to Mainz Hbf station pair, with some services arriving at Mainz Römisches Theater. Use this guide to compare Prague and Mainz train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Prague
Arrival train stations in Mainz

Which Prague station do trains to Mainz leave from?

Trains from Prague to Mainz leave from Praha hlavní nádraží. The station is 0 miles (1 km) from Prague city centre at Wilsonova 300/8, 120 00 Praha 2, Czechia.
Praha hlavní nádražíWilsonova 300/8, 120 00 Praha 2, Czechia+420 221 111 122WifiLockersParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to Praha hlavní nádraží from Prague city centre

Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:

TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · $2 · every ~3 min
Nj · 8m · $17
Bus478 · 5m
Tram17, 93 · 10m · $3 · every ~23 min
17, 93 · 12m · $3 · every ~23 min
SubwayC · 5m · $3 · every ~29 min

Praha hlavní nádraží train station facilities and services

Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.

Food and drink

Food options include: Restaurant Fantova Kavárna, Sushi Time

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.

Parking, taxis and toilets

Available at Praha hlavní nádraží: Parking, Taxis, WC.

Bike and car services

Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.

Shops, hotels and contact

Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.

Praha-HolesovicePartyzánská 26, Holesovice, Prague 7, Czechia+420 296 191 817WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
City-centre transport

Getting to Praha-Holesovice from Prague city centre

Praha-Holesovice is 2 km from Prague city centre. Public transport options include:

TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · $2 · every ~3 min
Nj · 8m · $17
Bus478 · 5m
Tram17, 93 · 10m · $3 · every ~23 min
17, 93 · 12m · $3 · every ~23 min
SubwayC · 5m · $3 · every ~29 min

Praha-Holesovice train station facilities and services

Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.

Food and drink

Food options include: Restaurant Na Kovárně, Cross Club

Wi-Fi and ATMs

Free. ATMs are available in the train station.

Tickets and information

Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.

Luggage and lost property

Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.

Parking, taxis and toilets

Available at Praha-Holesovice: Parking, Taxis, WC.

Bike and car services

Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.

Shops, hotels and contact

Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.

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