How to travel from Mainz to Prague

Fri, Mar 06
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Travel by bus, train, flight with
Deutsche Bahn
FlixBus
Lufthansa
Alex
Air Dolomiti
1,000+ more
Deutsche Bahn
FlixBus
Lufthansa
Alex
Air Dolomiti
1,000+ more
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Travel Information

Compare bus, train, and flight for Mainz to Prague

Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $99.

Distance: 272 miles (439 km)

Compare train with

Most popular
Train
Bus
Flight

$108

Average price

$47

Average price

Cheapest

$202

Average price

9h 5m

Average total duration

8h 35m

Onboard

+

30m

Additional time*

7h 40m

Average total duration

7h 10m

Onboard

+

30m

Additional time*

4h 29m

Average total duration

Fastest

1h 29m

Onboard

+

3h 0m

Additional time*

0.1 - 0.4kg

CO2 emissions

Lowest

0.4 - 1.1kg

CO2 emissions

1.3 - 2.6kg

CO2 emissions

Deutsche Bahn

Most popular train company

FlixBus

Most popular bus company

Lufthansa

Most popular airline

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Travel options
from Mainz to Prague

How to get from Mainz to Prague by train, bus or flight.

Our recommendation

bus

The best way to travel from Mainz to Prague is by taking a bus because it’s the best combination of price and speed.

Regiojet(Amsterdam -> Prague)
10:00PM6h45
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
04:45AMPrague, Central Train Station
$481One-way
0 transfers

Cheapest

Regiojet(Amsterdam -> Prague)
10:00PM6h45
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
04:45AMPrague, Central Train Station
$481One-way
0 transfers

Fastest

CondorDE4409
09:20AM1h00
Frankfurt am Main Airport
10:20AMPrague Vaclav Havel Airport
$2501One-way
0 transfers

Other options

Deutsche Bahn4255 · ICE 527 · 3565+Alex357
08:17AM8h04
Mainz Hbf
04:21PMPrague hlavní nádraží
$951One-way
3 transfers
Deutsche Bahn29507 · ICE 692 · IC 2443 · RJ 383
09:11AM8h14
Mainz Hbf
05:25PMPrague hlavní nádraží
$1301One-way
3 transfers
Deutsche Bahn4255 · ICE 1557 · RJ 383
08:17AM9h08
Mainz Hbf
05:25PMPrague hlavní nádraží
$1441One-way
2 transfers
Regiojet(Amsterdam -> Prague)
10:00PM6h48
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
04:48AMPraha, ÚAN Florenc
$481One-way
0 transfers
FlixBusFlixBus
04:00PM8h05
Mainz, Binger Schlag (Kurzzeitparkplatz)
12:05AMPraha, Na Knížecí
$531One-way
0 transfers
FlixBusFlixBus
04:00PM8h25
Mainz, Binger Schlag (Kurzzeitparkplatz)
12:25AMPrague, Central Train Station
$531One-way
0 transfers
CondorDE4407
02:15PM1h00
Frankfurt am Main Airport
03:15PMPrague Vaclav Havel Airport
$2501One-way
0 transfers
Air DolomitiLH5652
08:45AM1h05
Frankfurt am Main Airport
09:50AMPrague Vaclav Havel Airport
$3321One-way
0 transfers
Air DolomitiEN8950
08:45AM1h05
Frankfurt am Main Airport
09:50AMPrague Vaclav Havel Airport
$3321One-way
0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Travel from Mainz to Prague

Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Prague.

FAQs
There are 3 options to travel between Mainz and Prague including taking a bus, train, and flight.
The cheapest way to travel from Mainz to Prague is a bus with an average price of $32 (€26).

This is compared to other travel options from Mainz to Prague:

A bus is $6 (€5) less than a train for this route with tickets for a train from Mainz to Prague costing on average $38 (€31).

A bus is $67 (€54) less than a flight for this route with tickets for a flight from Mainz to Prague costing on average $99 (€80).

The fastest way to travel from Mainz to Prague is by flight with an average journey time of 1h 0m.

Other travel options to Prague take longer:

Bus takes on average 6h 45m.

Train takes on average 7h 41m.

The distance from Mainz to Prague is approximately 272 miles (439 km).
The average frequency per day from Mainz to Prague is:
  • Around 73 flights per day.
  • Around 9 trains per day.
  • Around 6 buses per day.

However, we recommend checking specific travel dates for your route between Mainz and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Mainz to Prague:
  • Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
  • Trains mostly depart from Mainz Hbf and arrive in Prague hlavní nádraží.
  • Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Praha, ÚAN Florenc.
If finding a good deal is your main consideration for your trip from Mainz to Prague, then we'll help you find the best value travel companies for you:
  • Travel with FlixBus, BlaBlaCar to go to Prague by bus.
  • Travel with Lufthansa, Air Dolomiti, LOT Polish Airlines, Condor, Eurowings to go to Prague by flight.
  • Travel with Deutsche Bahn, Alex, České dráhy to go to Prague by train.
Yes, there are direct services available from Mainz to Prague with the following travel companies:
  • 3 direct buses per day with FlixBus, BlaBlaCar.
  • 9 direct flights per day with Lufthansa, Air Dolomiti, Condor.
Omio customers who travel from Mainz to Prague often also extend their vacation to go to Vienna, Budapest, Berlin, Dresden, Munich. Omio can help you plan your trip by finding the best connections between Prague and these popular destinations at a great price.
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