How to travel from Mainz to Prague

Tue, Sep 08
+ Add return
Travel by bus, train, flight with
alex-Länderbahn und Vogtlandbahn-GmbH
FlixBus
Air Dolomiti
Deutsche Bahn
České dráhy
1,000+ more
alex-Länderbahn und Vogtlandbahn-GmbH
FlixBus
Air Dolomiti
Deutsche Bahn
České dráhy
1,000+ more
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Travel Information

Compare bus, train, and flight for Mainz to Prague

Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $45 For those with little time, consider booking a flight, which has an average total journey time of 3h 29m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $45, while a flight costs an average of $168.

Distance: 272 miles (439 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

$85

Average price

$45

Average price

Cheapest

$168

Average price

$120

Average price

(fuel + tolls)

8h 58m

Average total duration

8h 28m

Onboard

+

30m

Additional time*

7h 30m

Average total duration

7h 0m

Onboard

+

30m

Additional time*

3h 29m

Average total duration

Fastest

1h 29m

Onboard

+

2h 0m

Additional time*

5h 50m

Average total duration

(door-to-door)

0.1 - 0.4kg

CO2 emissions

Lowest

0.4 - 1.1kg

CO2 emissions

1.3 - 2.6kg

CO2 emissions

-

CO2 emissions

alex-Länderbahn und Vogtlandbahn-GmbH

Most popular train company

FlixBus

Most popular bus company

Air Dolomiti

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Mainz to Prague is a bus with an average price of $45 (€37).

This is compared to other travel options from Mainz to Prague:

A bus is $39 (€32) less than a train for this route with tickets for a train from Mainz to Prague costing on average $85 (€68).

A bus is $123 (€99) less than a flight for this route with tickets for a flight from Mainz to Prague costing on average $168 (€136).

The fastest way to travel from Mainz to Prague is by flight with an average journey time of 3h 29m.

Other travel options to Prague take longer:

Bus takes on average 7h 30m.

Train takes on average 8h 58m.

It's helpful to compare your options as there are 3 ways to travel between Mainz and Prague including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Mainz to Prague among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.

Tickets start at around $85 (€68) compared to roughly $120 (€97) in fuel and tolls — a saving of about $35 (€29). The journey takes 8h 28m versus 5h 50m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.

Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.

Travel options
from Mainz to Prague

How to get from Mainz to Prague by train, bus or flight.

Our recommendation

bus

The best way to travel from Mainz to Prague is by taking a bus because it’s the best combination of price and speed.

  • FlixBus
    3:00 PM8h05
    Mainz
    11:05 PMPrague
    $391One-way
    0 transfers

Cheapest

  • FlixBus
    3:00 PM8h05
    Mainz
    11:05 PMPrague
    $391One-way
    0 transfers

Fastest

  • FlixBus
    3:00 PM8h05
    Mainz
    11:05 PMPrague
    $391One-way
    0 transfers

Other options

  • FlixBus
    3:15 AM10h45
    Mainz
    2:00 PMPrague
    $491One-way
    0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Travel from Mainz to Prague

Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Prague.

FAQs
There are 3 options to travel between Mainz and Prague including taking a bus, train, and flight.
The cheapest way to travel from Mainz to Prague is a bus with an average price of $45 (€37).

This is compared to other travel options from Mainz to Prague:

A bus is $39 (€32) less than a train for this route with tickets for a train from Mainz to Prague costing on average $85 (€68).

A bus is $123 (€99) less than a flight for this route with tickets for a flight from Mainz to Prague costing on average $168 (€136).

The fastest way to travel from Mainz to Prague is by flight with an average journey time of 3h 29m.

Other travel options to Prague take longer:

Bus takes on average 7h 30m.

Train takes on average 8h 58m.

The distance from Mainz to Prague is approximately 272 miles (439 km).
The average frequency per day from Mainz to Prague is:
  • Around 69 flights per day.
  • Around 8 trains per day.
  • Around 5 buses per day.

However, we recommend checking specific travel dates for your route between Mainz and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Mainz to Prague:
  • Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
  • Trains mostly depart from Mainz Hbf and arrive in Prague hlavní nádraží.
  • Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Praha, ÚAN Florenc.
If finding a good deal is your main consideration for your trip from Mainz to Prague, then we'll help you find the best value travel companies for you:
  • Travel with FlixBus, BlaBlaCar to go to Prague by bus.
  • Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy to go to Prague by train.
  • Travel with Air Dolomiti, Lufthansa, Lot Polish Airlines, Eurowings, Condor Flugdienst to go to Prague by flight.
Yes, there are direct services available from Mainz to Prague with the following travel companies:
  • 3 direct buses per day with FlixBus, BlaBlaCar.
  • 9 direct flights per day with Air Dolomiti, Lufthansa, Eurowings, Condor Flugdienst.
Omio customers who travel from Mainz to Prague often also extend their vacation to go to Vienna, Budapest, Berlin, Dresden, Munich. Omio can help you plan your trip by finding the best connections between Prague and these popular destinations at a great price.
Most travelers need at least three days in Prague to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.
In Prague, you can enjoy panoramic views from Petrin Hill and visit attractions like the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady with its trendy bars and cafes, or take a boat cruise on the Vltava River for unique views of the city's landmarks. Delve into Czech history at the National Museum, and enjoy a classical music concert in one of the city's historic venues. Must-see sights include Prague Castle, Charles Bridge, Old Town Square with the Astronomical Clock, St. Vitus Cathedral, and the historic Jewish Quarter.
To fully experience Prague, 3 to 4 days are recommended, allowing time to explore key attractions like Prague Castle, Charles Bridge, Old Town Square, and the Jewish Quarter, as well as enjoy local cuisine and culture.
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