Travel Information between Mainz and Prague
| 272 miles (438 km) | |
| Bus, train or flight | |
| $23 - $61 | |
| Train • $23 (€21) • 7 h 41 min | |
| Flight • $61 (€55) • 1 h 15 min | |
| FlixBus, Lufthansa or Deutsche Bahn |
Travel 272 miles (438 km) by bus, train or flight between Mainz and Prague. The most popular travel companies which serve this trip are FlixBus, Lufthansa or Deutsche Bahn among others. Travelers can even take a direct bus, flight or train from Mainz to Prague.
Travel optionsfrom Mainz to Prague
How to get from Mainz to Prague by train, bus or flight.
Our recommendation
The best way to travel from Mainz to Prague is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague)Cheapest
(Amsterdam -> Prague)Fastest
(Amsterdam -> Prague)Other options
FlixBus
FlixBus
FlixBus · FlixBusFind all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Mainz to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Prague.

There are 3 travel options from Mainz to Prague: bus, train or flight.
The cheapest way to travel to Prague from Mainz is a train with an average price of $23 (€21).
This is compared to other travel options from Mainz to Prague:
A train is $9 (€8) less than a bus for this route with tickets for a bus from Mainz to Prague costing on average $32 (€29).
Taking a train costs $38 (€34) less than taking a flight, which costs on average $61 (€55) for the same trip.
The quickest way to travel between Mainz and Prague is by flight, which takes on average 1 h 15 min compared to other travel options that take longer:
Bus takes on average 8 h 5 min.
Train takes 7 h 41 min on average.
The distance is approximately 272 miles (438 km) from Mainz to Prague.
The average frequency per day from Mainz to Prague is:
- Around 5 buses per day.
- 62 flights a day.
- 7 trains a day.
However, we recommend checking specific travel dates for your trip between Mainz and Prague as scheduled services by bus, train or flight can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from Mainz to Prague:
- Most travelers take a bus from Mainz, Binger Schlag (Kurzzeitparkplatz) to Prague, Central Train Station.
Omio works with many trusted partners that can help you travel the best way from Mainz to Prague:
- You can take a bus from Mainz to Prague with FlixBus. Cheap tickets can be found for $32 (€29) with FlixBus from Mainz to Prague.
- You can travel by plane between Mainz and Prague with Lufthansa, Eurowings or LOT Polish Airlines, and you can find Eurowings Mainz to Prague tickets for $61 (€55) on Omio.
- You can go to Prague from Mainz by train with Deutsche Bahn. You'll see cheap train tickets for $23 (€21) with Deutsche Bahn from Mainz to Prague on Omio.
Yes, there are direct routes from Mainz to Prague with the following travel companies:
- You can find 2 direct buses per day to take to Prague with FlixBus.
- You can find 6 direct flights per day to Prague with.
Direct services to Prague tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your trip.
Travelling from Mainz to Prague: related information
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