How to travel from Mainz to Prague

Fri, Jun 05
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Travel by bus, train, flight with
Deutsche Bahn
FlixBus
Air Dolomiti
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
1,000+ more
Deutsche Bahn
FlixBus
Air Dolomiti
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
1,000+ more
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Travel Information

Compare bus, train, and flight for Mainz to Prague

Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $94.

Distance: 272 miles (439 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

$129

Average price

$47

Average price

Cheapest

$215

Average price

$120

Average price

(fuel + tolls)

9h 5m

Average total duration

8h 35m

Onboard

+

30m

Additional time*

7h 35m

Average total duration

7h 5m

Onboard

+

30m

Additional time*

4h 29m

Average total duration

Fastest

1h 29m

Onboard

+

3h 0m

Additional time*

5h 50m

Average total duration

(door-to-door)

0.1 - 0.4kg

CO2 emissions

Lowest

0.4 - 1.1kg

CO2 emissions

1.3 - 2.6kg

CO2 emissions

-

CO2 emissions

alex-Länderbahn und Vogtlandbahn-GmbH

Most popular train company

FlixBus

Most popular bus company

Air Dolomiti

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Mainz to Prague is a bus with an average price of $47 (€38).

This is compared to other travel options from Mainz to Prague:

A bus is $83 (€67) less than a train for this route with tickets for a train from Mainz to Prague costing on average $129 (€104).

A bus is $168 (€136) less than a flight for this route with tickets for a flight from Mainz to Prague costing on average $215 (€173).

The fastest way to travel from Mainz to Prague is by flight with an average journey time of 1h 29m.

Other travel options to Prague take longer:

Bus takes on average 7h 5m.

Train takes on average 8h 35m.

It's helpful to compare your options as there are 3 ways to travel between Mainz and Prague including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Mainz to Prague among Omio's users.

Travel options
from Mainz to Prague

How to get from Mainz to Prague by train, bus or flight.

Our recommendation

bus

The best way to travel from Mainz to Prague is by taking a bus because it’s the best combination of price and speed.

  • RegioJet a.s.(Amsterdam -> Prague)
    10:00 PM6h48
    Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
    4:48 AMPraha, ÚAN Florenc
    $491One-way
    0 transfers

Cheapest

  • RegioJet a.s.(Amsterdam -> Prague)
    10:00 PM6h48
    Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
    4:48 AMPraha, ÚAN Florenc
    $491One-way
    0 transfers

Fastest

  • Condor FlugdienstDE4411
    8:25 PM1h00
    Frankfurt am Main Airport
    9:25 PMPrague Vaclav Havel Airport
    $1781One-way
    0 transfers

Other options

  • Deutsche BahnS8 · ICE 527 · 3565+alex-Länderbahn und Vogtlandbahn-GmbH357
    8:02 AM8h19
    Mainz Hbf
    4:21 PMPrague hlavní nádraží
    $1381One-way
    3 transfers
  • České dráhyICE 1557 · rj 383
    8:43 AM8h42
    Mainz Hbf
    5:25 PMPrague hlavní nádraží
    $1411One-way
    1 transfer
  • Deutsche BahnICE 1557 · RJ 383
    8:43 AM8h42
    Mainz Hbf
    5:25 PMPrague hlavní nádraží
    $1741One-way
    1 transfer
  • FlixBusFlixBus
    4:00 PM8h05
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    12:05 AMPraha, Na Knížecí
    $561One-way
    0 transfers
  • FlixBusFlixBus
    4:00 PM8h25
    Mainz, Binger Schlag (Kurzzeitparkplatz)
    12:25 AMPrague, Central Train Station
    $561One-way
    0 transfers
  • EurowingsEW772
    2:25 PM1h10
    Cologne Bonn Airport
    3:35 PMPrague Vaclav Havel Airport
    $961One-way
    0 transfers
  • SmartwingsQS8037
    2:25 PM1h10
    Cologne Bonn Airport
    3:35 PMPrague Vaclav Havel Airport
    $1571One-way
    0 transfers
  • Deutsche BahnICE 1651+Condor FlugdienstDE4411
    12:43 PM8h42
    Mainz Hbf
    9:25 PMPrague Vaclav Havel Airport
    $2011One-way
    1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Travel from Mainz to Prague

Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Prague.

FAQs
There are 3 options to travel between Mainz and Prague including taking a bus, train, and flight.
The cheapest way to travel from Mainz to Prague is a bus with an average price of $47 (€38).

This is compared to other travel options from Mainz to Prague:

A bus is $83 (€67) less than a train for this route with tickets for a train from Mainz to Prague costing on average $129 (€104).

A bus is $168 (€136) less than a flight for this route with tickets for a flight from Mainz to Prague costing on average $215 (€173).

The fastest way to travel from Mainz to Prague is by flight with an average journey time of 1h 29m.

Other travel options to Prague take longer:

Bus takes on average 7h 5m.

Train takes on average 8h 35m.

The distance from Mainz to Prague is approximately 272 miles (439 km).
The average frequency per day from Mainz to Prague is:
  • Around 70 flights per day.
  • Around 8 trains per day.
  • Around 6 buses per day.

However, we recommend checking specific travel dates for your route between Mainz and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Mainz to Prague:
  • Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
  • Trains mostly depart from Mainz Hbf and arrive in Prague hlavní nádraží.
  • Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Praha, ÚAN Florenc.
If finding a good deal is your main consideration for your trip from Mainz to Prague, then we'll help you find the best value travel companies for you:
  • Travel with Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy to go to Prague by train.
  • Travel with FlixBus, BlaBlaCar to go to Prague by bus.
  • Travel with Air Dolomiti, Lufthansa, Lot Polish Airlines, Eurowings, Condor Flugdienst to go to Prague by flight.
Yes, there are direct services available from Mainz to Prague with the following travel companies:
  • 3 direct buses per day with FlixBus, BlaBlaCar.
  • 9 direct flights per day with Air Dolomiti, Lufthansa, Eurowings, Condor Flugdienst.
Omio customers who travel from Mainz to Prague often also extend their vacation to go to Vienna, Budapest, Berlin, Dresden, Munich. Omio can help you plan your trip by finding the best connections between Prague and these popular destinations at a great price.
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