Mainz to Lyon train with TGV

Thu, Nov 13
+ Add return
TGV
TGV INOUI
Süwex
Regionale
Deutsche Bahn
1,000+ travel companies
TGV
TGV INOUI
Süwex
Regionale
Deutsche Bahn
1,000+ travel companies
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The cheapest and fastest trains from Mainz to Lyon

Showing times and prices for Nov 14

Cheapest price

$116

Average price

$133

Fastest journey

5 h 17 m

Average duration

5 h 40 m

Trains per day

2

Distance

536 km

Cheap tickets

The best way to find a cheap train ticket from Mainz to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Mainz to Lyon will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $116.

Fast trains

Of the 2 trains that leave Mainz for Lyon on Fri, Nov 14, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Nov 14 the direct trains cover the 536 km distance in an average of 5 h 40 m but if you time it right, some trains will get you there in just 5 h 17 m .

On Fri, Nov 14 the slowest trains will take 6 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

TGV INOUI
04:56AM6h02
Mainz
10:58AMLyon
$1161One-way
0 transfers
TGV INOUI
12:39PM5h17
Mainz
05:56PMLyon
$1511One-way
0 transfers

Travel Information

Compare train, bus, and flight for Mainz to Lyon

Omio recommends booking the train as it is the most popular option from Mainz to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a flight which can get you there in 1h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a flight costs an average of €73.

Distance: 333 miles (536 km)

Compare train with

Most popular
Train
Flight
Bus

€127

Average price

€165

Average price

€41

Average price

Cheapest

6h 33m

Average total duration

6h 3m

Onboard

+

30m

Additional time*

4h 25m

Average total duration

Fastest

1h 25m

Onboard

+

3h 0m

Additional time*

9h 20m

Average total duration

8h 50m

Onboard

+

30m

Additional time*

0.2 - 0.5kg

CO2 emissions

Lowest

1.6 - 3.2kg

CO2 emissions

0.5 - 1.3kg

CO2 emissions

TGV

Most popular train company

Lufthansa

Most popular airline

FlixBus

Most popular bus company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Mainz to Lyon train times

The table below shows live departures for Mainz to Lyon trains for today, Thursday, November 13. You can also manually refresh the results below to see updated train journeys.

Last updated at 11:29 AM
ProviderDepartsDurationArrivesTransfers
Tickets
sncf-tgv-inoui12:39 PM Mainz
5h17
5:56 PM Lyon0 transfersDirect
Friday, November 14
sncf-tgv-inoui4:56 AM Mainz
6h02
10:58 AM Lyon0 transfersDirect

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Mainz to Lyon by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 14
Sat
Nov 15
Sun
Nov 16
Mon
Nov 17
Tue
Nov 18
Wed
Nov 19
Thu
Nov 20

Journey information

Overview: Train from Mainz to Lyon

GermanyGermany
FranceFrance
Icon of train

Trains from Mainz to Lyon run on average 3 times per day, taking around 6h 3m. Cheap train tickets for this journey start at $91 (€74) but you can travel from only $33 (€26) by bus.

There are 1 trains per day. The earliest train runs at 03:15, the last at 22:25. The fastest train covers the 333 miles (536 km) distance in 5h 17m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $33 (€26)
Distance
333 miles (536 km)
Average train duration
6h 3m
Cheapest ticket price
$91 (€74)
Trains per day
3
Direct trains
1
Fastest train
5h 17m
First train
03:15
Last train
22:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $33 (€26)

Train companies: TGV, TGV INOUI, Süwex from Mainz to Lyon trainsTGV, TGV INOUI, Süwex trains will get you between Mainz and Lyon from $33 (€26). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

TGV

About
TGV is a high-speed train company based in France. It operates a fleet of modern trains that can reach speeds of up to 320 km/h. The TGV offers a variety of train types, including the TGV Duplex, TGV Lyria, TGV InOui, and TGV OuiGo. Each train type provides different amenities, such as Wi-Fi, power outlets, and comfortable seating. Ticket options include Standard, Flexi, and Prem’s. Onboard facilities feature a bar, restaurant, and luggage storage. Popular TGV routes include Paris to Lyon, Paris to Marseille, and Paris to Lille.
Luggage & cancellation policy
TGV frequency
1 a day
Luggage included
2 pieces of hand luggage and 1 suitcase included in ticket price
Luggage storage
Dedicated luggage areas at end of carriages and overhead racks
Cancellation Policy
According to fare conditions and ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals and bar service, at-seat dining in first class
Seat reservation
Included in first class, optional fee in second class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket, guide dogs travel free
Quiet zone

TGV INOUI

About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a "Bistro TGV INOUI" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable.
Luggage & cancellation policy
Average Duration
5h 17m
Cheapest Price
$95 (€77)
TGV INOUI frequency
1 a day
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the train
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone

Süwex

Luggage & cancellation policy
Average Duration
6h 39m
Cheapest Price
$122 (€99)
Süwex frequency
1 a day

FAQs: Trains from Mainz to Lyon

Find answers to the most common questions about traveling from Mainz to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

FAQs
The distance by train from Mainz to Lyon is 333 miles (536 km).
The first train from Mainz to Lyon leaves at 3:15 AM.
Yes, there is a high-speed train from Mainz to Lyon.
For a fulfilling experience in Lyon, spending 2 to 3 days is ideal. This allows you to explore key attractions such as Vieux Lyon, Basilica of Notre-Dame de Fourvière, and the Musée des Confluences, while also enjoying the city's renowned gastronomy and vibrant cultural scene.
The last train from Mainz to Lyon leaves at 10:25 PM.
Yes, you can take the train from Mainz to Lyon.
Yes, there is a direct train from Mainz to Lyon. This service operates 1 times per day, provided by TGV INOUI.
In Lyon, you can explore Les Halles de Lyon Paul Bocuse, an indoor market offering gourmet food, take a river cruise on the Rhône and Saône, and discover the secret passageways of the traboules in Vieux Lyon. Attend a performance at the Opéra de Lyon or visit the Institut Lumière for cinema history. Don't miss the Basilica of Notre-Dame de Fourvière for panoramic views, Vieux Lyon for its Renaissance architecture, Parc de la Tête d'Or with its zoo and botanical garden, the Musée des Confluences, or the bustling Place Bellecour.
A day trip from Mainz to Lyon is not feasible as the journey takes 5h 17m. Trains operate 3 times per day. The distance is 333 miles (536 km).
The train journey from Mainz to Lyon offers scenic views, particularly as it passes through the Rhine Valley with its charming vineyards and historic castles, and continues through the picturesque landscapes of eastern France.
Train ticket prices from Mainz to Lyon can vary. The cheapest ticket starts at $91 (€74), while the average price is around $157 (€127).
The cheapest way to get from Mainz to Lyon is by bus, with a cost of around $33 (€26).
The train from Mainz to Lyon takes 5h 17m and runs 3 per day.
The train station in Mainz that goes to Lyon is Frankfurt (Main) Hbf, which connects to Lyon Part Dieu.
Unfortunately, there is no night train available from Mainz to Lyon.

popular train stations

Popular train stations from Mainz to Lyon

Mainz
Lyon
The major train station for departures in Mainz is Mainz Hbf. Find all the information you need to know about services, amenities and connections at Mainz Hbf for your trip from Mainz to Lyon.
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Ticket Office Hours
  • Monday: 06:00 - 21:15
  • Tuesday: 06:00 - 21:15
  • Wednesday: 06:00 - 21:15
  • Thursday: 06:00 - 21:15
  • Friday: 06:00 - 21:15
  • Saturday: 07:00 - 19:00
  • Sunday: 08:00 - 20:00
ticketOfficeHours
Distance to city center
2 km
Dining
Dining
  • Mangal
  • Asia Wok
  • Bistrorante Midi
  • McDonald's
Hotel
Hotel
  • Advena Europa Hotel
  • GuestHouse Mainz
  • Terminus
  • Hotel Moguntia

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