The cheapest and fastest buses from Mainz to Prague
Cheapest price
$34
Average price
$41
Fastest journey
8 h 5 m
Average duration
9 h 25 m
Buses per day
2
Distance
439 km
The best way to find a cheap bus ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mainz to Prague will cost around $41 if you buy it on the day, but the cheapest tickets can be found for only $34.
Of the 2 buses that leave Mainz for Prague on Thu, Nov 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 439 km distance in an average of 9 h 25 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Thu, Nov 06 the slowest buses will take 10 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Mainz to Prague
Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 35m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a flight costs an average of €50.
Distance: 272 miles (439 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€37 Average price Cheapest | €83 Average price | €119 Average price |
7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 8h 3m Average total duration 7h 33m Onboard + 30m Additional time* | 4h 35m Average total duration Fastest 1h 35m Onboard + 3h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Mainz to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:15AM | Arrival Time 04:00PM | Duration 10h45 | Departure days Wed, Fri, Sat | Cheapest price $61 |
Operator BlaBlaCar | Departure Time 02:50PM | Arrival Time 07:50PM | Duration 5h00 | Departure days Wed | Cheapest price $39 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 12:05AM | Duration 8h05 | Departure days Fri, Sat | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 04:20PM | Arrival Time 10:10PM | Duration 5h50 | Departure days Wed | Cheapest price $39 |
Operator Regiojet | Departure Time 10:00PM | Arrival Time 04:48AM | Duration 6h48 | Departure days Wed, Fri, Sat | Cheapest price $32 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 10:40AM | Duration 11h10 | Departure days Fri, Sat | Cheapest price $61 |
Live departures
Mainz to Prague bus times
The table below shows live departures for Mainz to Prague buses for today, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
(Amsterdam -> Prague) | 9:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 3:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
| Thursday, November 6 | |||||
![]() | 3:15 AM Mainz | 10h45 | 2:00 PM Prague | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Nov 15
Nov 16
Nov 17
Nov 18
Nov 19
Nov 20
Nov 21
Nov 22
Nov 23
Nov 24
Nov 25
Nov 26
Journey information
Overview: Bus from Mainz to Prague
Distance 272 miles (439 km) |
Average bus duration 7h 6m |
Cheapest ticket price $31 (€25) |
Buses per day 5 |
Direct buses 3 |
Fastest bus 6h 48m |
First bus 02:05 |
Last bus 23:40 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Mainz to Prague start from as low as $31 (€25) if booked well in advance.
- Standard Fares: Typically, trains cost $45 (€37) depending on the train type and class.
Bus providers: FlixBus, BlaBlaCar from Mainz to PragueYou can travel by bus between Mainz to Prague with FlixBus, BlaBlaCar for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Mainz to Prague

Passengers board the bus most frequently from Mainz, Binger Schlag (Kurzzeitparkplatz), which is located around 2.1 miles (3.4 km) away from the city centre, and they get off the bus at Prague, Central Train Station, located 1.8 miles (2.9 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Mainz to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Mainz to Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Bus: 131, 174, 180 Metro: A Train: S4, S5
Most popular bus connections from Mainz
More options for your journey from Mainz to Prague
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