- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
The best way to find a cheap train ticket from Düsseldorf to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Prague will cost around $209 if you buy it on the day, but the cheapest tickets can be found for only $46.
It's difficult to get from Düsseldorf to Prague without transferring at least 3 times.
26846 · ICE 827 · 3557+
353
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ICE 523 · 3561+
355
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ICE 527 · 3565 · Bus RE25 · EX 357
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ICE 1541 · IC 2449 · rj 10171 · rj 171
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FlixTrain+
FlixBus
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ICE 621 · 3569 · Bus RE25 · EX 359
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ICE 527 · 3565 · Bus RE25 · EX 357
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ICE 621 · R 3569 · EC 60359 · EC 359
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ICE 527 · R 3565 · EC 60357 · EC 357
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ICE 625 · 3573 · Bus RE25 · EX 361
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Trains from Düsseldorf to Prague run on average 10 times per day, taking around 8h 42m. Cheap train tickets for this journey start at $36 (€30) but you can travel from only $30 (€25) by bus.
The earliest train runs at 00:10, the last at 23:54. The fastest train covers the 343 miles (553 km) distance in 7h 31m.
Distance 343 miles (553 km) |
Average train duration 8h 42m |
Cheapest ticket price $36 (€30) |
Trains per day 10 |
Fastest train 7h 31m |
First train 12:10 AM |
Last train 11:54 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Tue |
Best time to book 56 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Düsseldorf to Prague.
The table below shows live departures for Düsseldorf to Prague trains for today, Saturday, October 31. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 920 · RJ 173+ 81608 | Delayed 1:32 AM 2:32 AMDüsseldorf Hbf | 10h53 | 1:25 PM Prague hlavní nádraží | 2 transfers | |
ICE 1541 · RJ 171 | Delayed 10:53 PM 11:51 PMDüsseldorf Hbf | 11h34 | 11:25 AM Prague hlavní nádraží | 1 transfer | |
| Sunday, November 1 | |||||
26846 · ICE 827 · 3557+ 353 | 2:43 AM Düsseldorf Hbf | 9h38 | 12:21 PM Prague hlavní nádraží | 3 transfers | |
RE 26846 · ICE 827 · R 3557 · EC 60353 | 2:43 AM Düsseldorf Hbf | 9h38 | 12:21 PM Prague hlavní nádraží | 4 transfers | |
ICE 523 · 3561+ 355 | On time 4:56 AM Düsseldorf Hbf | 9h25 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 523 · R 3561 · EC 60355 · EC 355 | On time 4:56 AM Düsseldorf Hbf | 9h25 | 2:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 843 · RJ 175 | On time 5:50 AM Düsseldorf Hbf | 9h25 | 3:15 PM Prague-Holešovice | 1 transfer | |
ICE 843 · rj 175 | On time 5:50 AM Düsseldorf Hbf | 9h25 | 3:15 PM Prague-Holešovice | 1 transfer | |
ICE 527 · R 3565 · EC 60357 · EC 357 | On time 7:21 AM Düsseldorf Hbf | 9h00 | 4:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 527 · 3565 · Bus RE25 · EX 357 | On time 7:21 AM Düsseldorf Hbf | 9h00 | 4:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 25 · ICE 513 · ICE 1557 · S1 | On time 7:25 AM Düsseldorf Hbf | 9h45 | 5:10 PM Prague hlavní nádraží | 5 transfers | |
ICE 845 · rj 383 | On time 7:50 AM Düsseldorf Hbf | 9h35 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 845 · RJ 383 | On time 7:50 AM Düsseldorf Hbf | 9h35 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 529 · ICE 692 · IC 2443 · rj 383 | On time 8:19 AM Düsseldorf Hbf | 9h06 | 5:25 PM Prague hlavní nádraží | 3 transfers | |
ICE 621 · R 3569 · EC 60359 · EC 359 | On time 9:21 AM Düsseldorf Hbf | 9h00 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 621 · 3569 · Bus RE25 · EX 359 | On time 9:21 AM Düsseldorf Hbf | 9h00 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 217 · ICE 1559 · S1 · 28010 | On time 9:32 AM Düsseldorf Hbf | 9h38 | 7:10 PM Prague hlavní nádraží | 4 transfers | |
ICE 217 · ICE 1559 · S 31747 · Os 28010 | On time 9:32 AM Düsseldorf Hbf | 9h38 | 7:10 PM Prague hlavní nádraží | 4 transfers | |
ICE 847 · rj 177 | On time 9:49 AM Düsseldorf Hbf | 9h26 | 7:15 PM Prague-Holešovice | 1 transfer | |
ICE 625 · R 3573 · EC 60361 · EC 361 | On time 11:20 AM Düsseldorf Hbf | 9h01 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 625 · 3573 · Bus RE25 · EX 361 | On time 11:20 AM Düsseldorf Hbf | 9h01 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 202 · RJ 385 | On time 11:34 AM Düsseldorf Hbf | 9h51 | 9:25 PM Prague hlavní nádraží | 1 transfer | |
RE 26717 · ICE 849 · rj 385 | 11:36 AM Düsseldorf Hbf | 9h49 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
RE 26814 · ICE 15 · ICE 598 · IC 2049 | 11:40 AM Düsseldorf Hbf | 9h45 | 9:25 PM Prague hlavní nádraží | 4 transfers | |
FlixTrain+ FlixBus | 12:38 PM Düsseldorf Hbf | 13h02 | 1:40 AM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 12:38 PM Düsseldorf Hbf | 14h52 | 3:30 AM Praha, ÚAN Florenc | 1 transfer | |
ICE 629 · R 3577 · EC 60363 · EC 363 | On time 1:18 PM Düsseldorf Hbf | 9h04 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
ICE 629 · 3577 · Bus RE25 · EX 363 | On time 1:18 PM Düsseldorf Hbf | 9h04 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
ICE 200 · RJ 179 | On time 1:34 PM Düsseldorf Hbf | 9h57 | 11:31 PM Prague hlavní nádraží | 1 transfer | |
IC 2201 · ICE 1519 · ICE 596 · IC 2047 | On time 1:47 PM Düsseldorf Hbf | 9h44 | 11:31 PM Prague hlavní nádraží | 4 transfers | |
ICE 723 · ICE 1655 · NJ 457 | On time 3:19 PM Düsseldorf Hbf | 9h07 | 12:26 AM Prague hlavní nádraží | 2 transfers | |
ICE 1749 · IC 2045 · S 31775 · Os 28023 | On time 3:41 PM Düsseldorf Hbf | 14h29 | 6:10 AM Prague hlavní nádraží | 4 transfers | |
ICE 1749 · IC 2045 · S1 · 28023 | On time 3:41 PM Düsseldorf Hbf | 14h29 | 6:10 AM Prague hlavní nádraží | 4 transfers | |
IC 2203 · ICE 1611 · ICE 594 · IC 2045 | On time 3:47 PM Düsseldorf Hbf | 14h23 | 6:10 AM Prague hlavní nádraží | 6 transfers | |
FlixTrain+ FlixBus | 4:38 PM Düsseldorf Hbf | 12h02 | 4:40 AM Praha, ÚAN Florenc | 1 transfer | |
FlixTrain+ FlixBus | 4:38 PM Düsseldorf Hbf | 12h22 | 5:00 AM Prague, Central Train Station | 1 transfer | |
ICE 727 · ICE 1657 · S1 · 28018 | On time 5:19 PM Düsseldorf Hbf | 14h51 | 8:10 AM Prague hlavní nádraží | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
The train connection between Düsseldorf and Prague offers a convenient way to travel between these two cities. Passengers can choose from several providers, including Deutsche Bahn, FlixTrain, and alex-Länderbahn und Vogtlandbahn-GmbH. With comfortable seating and scenic views along the route, this journey is an excellent option for those looking to explore both destinations without the hassle of driving or flying.
The train connection from Düsseldorf to Prague takes approximately 8 hours and 59 minutes, with a total of 6 connections available per day. This route is not direct, requiring at least one transfer during the journey. The average layover time between trains is about 1 hour and 10 minutes.
The first daily train journey from Düsseldorf to Prague departs at 07:18, providing an early start for travelers eager to explore the beautiful city of Prague. The last departure is scheduled for 21:52, allowing those who wish to enjoy a full day in Düsseldorf before heading out in the evening.
The cheapest ticket price for the train connection from Düsseldorf to Prague is €14. The average ticket price typically hovers around €50, making it a budget-friendly option for travelers looking to explore these vibrant cities.
Prague Castle, dating back to the 9th century, is not only one of the largest ancient castles in the world but also a symbol of Czech history and culture. Its stunning architecture showcases various styles from Gothic to Baroque, with highlights including St. Vitus Cathedral and the picturesque Golden Lane that transport you through centuries of royal heritage. As we explore its vast grounds, you'll feel like you've stepped into a fairy tale where every corner tells a story.
The Charles Bridge, completed in 1402 and adorned with 30 statues of saints, has been an iconic connection between Prague's Old Town and Lesser Town for over six centuries. This cobblestone marvel offers breathtaking views along the Vltava River while serving as a vibrant hub for artists and musicians who bring life to this historic thoroughfare. Walking across it feels like traversing time itself—each step echoing tales from medieval merchants to modern-day lovers.
Old Town Square is truly the heart of Prague; it's where history comes alive amidst colorful baroque buildings and bustling cafes that have witnessed countless events since its establishment in the 12th century. The square features remarkable landmarks such as the Astronomical Clock—a masterpiece that draws crowds every hour—and Týn Church with its striking spires dominating skyline views. Here at Old Town Square, you can immerse yourself in local traditions while savoring delicious pastries or simply soaking up an atmosphere rich with stories waiting to be discovered.
Find answers to the most common questions about traveling from Düsseldorf to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Düsseldorf to Prague trains use the Düsseldorf Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Düsseldorf and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Düsseldorf Hbf is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Zaxopondeiva Cafe, Lauren's Cafe, China Imbiss, Fu chu yuan
Wi-Fi is available at Düsseldorf Hbf. ATMs are available at Düsseldorf Hbf.
Ticket office support is available at Düsseldorf Hbf. Information desks are available at Düsseldorf Hbf.
Luggage storage is available at Düsseldorf Hbf. Lost and found is available at the station.
Available at Düsseldorf Hbf: Parking, Taxis, WC.
Available at Düsseldorf Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Hbf.
Nearby hotels include Hotel Lindenhof, Hotel Batavia, Sir Astor, Lady Astor.
Düsseldorf Friedrichstadt is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Friedrichstadt has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Fu chu yuan, Taj Mahal, Hai Xian, To1980
Wi-Fi is available at Düsseldorf Friedrichstadt. ATMs are available at Düsseldorf Friedrichstadt.
Ticket office support is available at Düsseldorf Friedrichstadt. Information desks are available at Düsseldorf Friedrichstadt.
Luggage storage is available at Düsseldorf Friedrichstadt. Lost and found is available at the station.
Available at Düsseldorf Friedrichstadt: Parking, Taxis, WC.
Available at Düsseldorf Friedrichstadt: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Friedrichstadt.
Nearby hotels include Hotel Batavia, Hotel Ko, Hotel Burns, Hotel Düsseldorf Mitte.
Düsseldorf Flughafen Terminal is 6 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Flughafen Terminal has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: L'Osteria, Bauernstube Deppe, Luxor Grill, McDonald's
Wi-Fi is available at Düsseldorf Flughafen Terminal. ATMs are available at Düsseldorf Flughafen Terminal.
Ticket office support is available at Düsseldorf Flughafen Terminal. Information desks are available at Düsseldorf Flughafen Terminal.
Luggage storage is available at Düsseldorf Flughafen Terminal. Lost and found is available at the station.
Available at Düsseldorf Flughafen Terminal: Parking, Taxis, WC.
Available at Düsseldorf Flughafen Terminal: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Flughafen Terminal.
Nearby hotels include Sheraton Düsseldorf Airport Hotel, Lindner Airport, Hotel Maritim.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Check train stations information for Düsseldorf and Prague, including where trains depart and arrive on this route.
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