- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$74
Average price
$163
Fastest journey
8 h 27 m
Average duration
8 h 34 m
Trains per day
33
Distance
553 km
The best way to find a cheap train ticket from Düsseldorf to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Prague will cost around $163 if you buy it on the day, but the cheapest tickets can be found for only $74.
It's difficult to get from Düsseldorf to Prague without transferring at least once.
FlixTrain+
FlixBus
ICE 645 · rj 479
RE 28535 · ICE 319 · ICE 1272 · EC 459
FlixTrain+
FlixBus
FlixTrain+
FlixBus
ICE 543 · rj 175
ICE 541 · rj 173
ICE 545 · RJ 383
ICE 545 · rj 383
ICE 549 · rj 385Omio recommends booking the train as it is the most popular option from Düsseldorf to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $36. For those with little time consider booking a flight which can get you there in 2h 7m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $36, and a flight costs an average of $75.
Distance: 343 miles (553 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$91 Average price | $226 Average price | $57 Average price Cheapest | $142 Average price (fuel + tolls) |
9h 45m Average total duration 9h 15m Onboard + 30m Additional time* | 5h 7m Average total duration Fastest 2h 7m Onboard + 3h 0m Additional time* | 10h 36m Average total duration 10h 6m Onboard + 30m Additional time* | 7h 48m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions | 0.6 - 1.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Düsseldorf to Prague:
A bus is $34 (€28) less than a train for this route with tickets for a train from Düsseldorf to Prague costing on average $91 (€75).
A bus is $169 (€139) less than a flight for this route with tickets for a flight from Düsseldorf to Prague costing on average $226 (€186).
Other travel options to Prague take longer:
Train takes on average 9h 15m.
Bus takes on average 10h 6m.
Tickets start at around $91 (€75) compared to roughly $142 (€117) in fuel and tolls — a saving of about $51 (€42). The journey takes 9h 15m versus 7h 48m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Düsseldorf to Prague trains for today, Wednesday, July 29. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
S 33160 · ICE 827 · R 3557 · EC 353 | Delayed 10:08 PM 12:08 AMDüsseldorf Hbf | 12h13 | 12:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 947 · RJ 479 | Delayed 7:50 PM Düsseldorf Hbf | 9h35 | 3:32 AM 3:32 AMPrague hlavní nádraží | 1 transfer | |
ICE 947 · rj 479 | On time 7:50 PM Düsseldorf Hbf | 9h35 | 5:25 AM Prague hlavní nádraží | 1 transfer | |
ICE 823 · ICE 590 · 16501 · S1 | On time 8:09 PM Düsseldorf Hbf | 13h01 | 9:10 AM Prague hlavní nádraží | 5 transfers | |
ICE 617 · EC 459 | On time 9:27 PM Düsseldorf Hbf | 11h58 | 9:25 AM Prague hlavní nádraží | 1 transfer | |
RE 28535 · ICE 319 · ICE 1272 · EC 459 | On time 9:58 PM Düsseldorf Hbf | 11h27 | 9:25 AM Prague hlavní nádraží | 3 transfers | |
ICE 619 · ICE 698 · IC 2449 · rj 387 | 11:45 PM Düsseldorf Hbf | 11h40 | 11:25 AM Prague hlavní nádraží | 3 transfers | |
ICE 619 · ICE 698 · IC 2449 · RJ 387 | On time 11:45 PM Düsseldorf Hbf | 11h40 | 11:25 AM Prague hlavní nádraží | 3 transfers | |
ICE 619+ 353 | 11:45 PM Düsseldorf Hbf | 12h36 | 12:21 PM Prague hlavní nádraží | 1 transfer | |
| Thursday, July 30 | |||||
ICE 921 · ICE 827 · R 3557 · EC 353 | 2:39 AM Düsseldorf Hbf | 9h42 | 12:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 541 · rj 173 | On time 4:49 AM Düsseldorf Hbf | 8h36 | 1:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 523 · R 3561 · EC 355 | Delayed 3:04 AM 4:58 AMDüsseldorf Hbf | 9h23 | 2:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 543 · rj 175 | On time 6:48 AM Düsseldorf Hbf | 8h27 | 3:15 PM Prague-Holešovice | 1 transfer | |
ICE 527 · R 3565 · EC 357 | On time 7:22 AM Düsseldorf Hbf | 8h59 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 545 · RJ 383 | On time 8:49 AM Düsseldorf Hbf | 8h36 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 545 · rj 383 | On time 8:49 AM Düsseldorf Hbf | 8h36 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 621 · 3569+ 359 | On time 9:22 AM Düsseldorf Hbf | 8h59 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 621 · R 3569 · EC 359 | On time 9:22 AM Düsseldorf Hbf | 8h59 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 847 · RJ 177 | On time 9:49 AM Düsseldorf Hbf | 9h26 | 7:15 PM Prague-Holešovice | 1 transfer | |
ICE 847 · rj 177 | On time 9:49 AM Düsseldorf Hbf | 9h26 | 7:15 PM Prague-Holešovice | 1 transfer | |
ICE 623 · ICE 2590 · IC 2441 · RJ 177 | On time 10:22 AM Düsseldorf Hbf | 8h53 | 7:15 PM Prague-Holešovice | 3 transfers | |
ICE 623 · ICE 2590 · IC 2441 · rj 177 | On time 10:22 AM Düsseldorf Hbf | 8h53 | 7:15 PM Prague-Holešovice | 3 transfers | |
ICE 625 · 3573+ 361 | On time 11:19 AM Düsseldorf Hbf | 9h02 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 625 · R 3573 · EC 361 | On time 11:19 AM Düsseldorf Hbf | 9h02 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
FlixTrain+ FlixBus | 12:38 PM Düsseldorf Hbf | 11h17 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 12:38 PM Düsseldorf Hbf | 10h57 | 11:35 PM Praha, ÚAN Florenc | 1 transfer | |
ICE 549 · rj 385 | On time 12:48 PM Düsseldorf Hbf | 8h37 | 9:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 549 · RJ 385 | On time 12:48 PM Düsseldorf Hbf | 8h37 | 9:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 629 · 3577+ 363 | On time 1:22 PM Düsseldorf Hbf | 9h00 | 10:22 PM Prague hlavní nádraží | 2 transfers | |
ICE 629 · R 3597 · EC 363 | On time 1:22 PM Düsseldorf Hbf | 9h00 | 10:22 PM Prague hlavní nádraží | 2 transfers | |
ICE 941 · RJ 179 | On time 1:50 PM Düsseldorf Hbf | 9h41 | 11:31 PM Prague hlavní nádraží | 1 transfer | |
ICE 941 · rj 179 | On time 1:50 PM Düsseldorf Hbf | 9h41 | 11:31 PM Prague hlavní nádraží | 1 transfer | |
ICE 721 · ICE 596 · IC 2047 · rj 179 | On time 2:22 PM Düsseldorf Hbf | 9h09 | 11:31 PM Prague hlavní nádraží | 3 transfers | |
ICE 721 · ICE 596 · IC 2047 · RJ 179 | On time 2:22 PM Düsseldorf Hbf | 9h09 | 11:31 PM Prague hlavní nádraží | 3 transfers | |
ICE 641 · NJ 457 | On time 2:48 PM Düsseldorf Hbf | 9h28 | 12:16 AM Prague-Holešovice | 1 transfer | |
ICE 723 · ICE 1655 · NJ 457 | On time 3:19 PM Düsseldorf Hbf | 8h57 | 12:16 AM Prague-Holešovice | 2 transfers | |
FlixTrain+ FlixBus | 4:38 PM Düsseldorf Hbf | 10h52 | 3:30 AM Praha, ÚAN Florenc | 1 transfer | |
FlixTrain+ FlixBus | 4:38 PM Düsseldorf Hbf | 11h02 | 3:40 AM Prague, Central Train Station | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Düsseldorf to Prague run on average 14 times per day, taking around 9h 15m. Cheap train tickets for this journey start at $50 (€41) but you can travel from only $36 (€30) by bus.
The earliest train runs at 00:10, the last at 23:54. The fastest train covers the 343 miles (553 km) distance in 8h 27m.
Distance 343 miles (553 km) |
Average train duration 9h 15m |
Cheapest ticket price $50 (€41) |
Trains per day 14 |
Fastest train 8h 27m |
First train 12:10 AM |
Last train 11:54 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Mon |
Best time to book 56 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
The train connection between Düsseldorf and Prague offers a convenient way to travel between these two cities. Passengers can choose from several providers, including Deutsche Bahn, FlixTrain, and alex-Länderbahn und Vogtlandbahn-GmbH. With comfortable seating and scenic views along the route, this journey is an excellent option for those looking to explore both destinations without the hassle of driving or flying.
The train connection from Düsseldorf to Prague takes approximately 8 hours and 59 minutes, with a total of 6 connections available per day. This route is not direct, requiring at least one transfer during the journey. The average layover time between trains is about 1 hour and 10 minutes.
The first daily train journey from Düsseldorf to Prague departs at 07:18, providing an early start for travelers eager to explore the beautiful city of Prague. The last departure is scheduled for 21:52, allowing those who wish to enjoy a full day in Düsseldorf before heading out in the evening.
The cheapest ticket price for the train connection from Düsseldorf to Prague is €14. The average ticket price typically hovers around €50, making it a budget-friendly option for travelers looking to explore these vibrant cities.
Prague Castle, dating back to the 9th century, is not only one of the largest ancient castles in the world but also a symbol of Czech history and culture. Its stunning architecture showcases various styles from Gothic to Baroque, with highlights including St. Vitus Cathedral and the picturesque Golden Lane that transport you through centuries of royal heritage. As we explore its vast grounds, you'll feel like you've stepped into a fairy tale where every corner tells a story.
The Charles Bridge, completed in 1402 and adorned with 30 statues of saints, has been an iconic connection between Prague's Old Town and Lesser Town for over six centuries. This cobblestone marvel offers breathtaking views along the Vltava River while serving as a vibrant hub for artists and musicians who bring life to this historic thoroughfare. Walking across it feels like traversing time itself—each step echoing tales from medieval merchants to modern-day lovers.
Old Town Square is truly the heart of Prague; it's where history comes alive amidst colorful baroque buildings and bustling cafes that have witnessed countless events since its establishment in the 12th century. The square features remarkable landmarks such as the Astronomical Clock—a masterpiece that draws crowds every hour—and Týn Church with its striking spires dominating skyline views. Here at Old Town Square, you can immerse yourself in local traditions while savoring delicious pastries or simply soaking up an atmosphere rich with stories waiting to be discovered.
Find answers to the most common questions about traveling from Düsseldorf to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Düsseldorf to Prague trains use the Düsseldorf Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Düsseldorf and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Düsseldorf Hbf is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Zaxopondeiva Cafe, Lauren's Cafe, China Imbiss, Fu chu yuan
Wi-Fi is available at Düsseldorf Hbf. ATMs are available at Düsseldorf Hbf.
Ticket office support is available at Düsseldorf Hbf. Information desks are available at Düsseldorf Hbf.
Luggage storage is available at Düsseldorf Hbf. Lost and found is available at the station.
Available at Düsseldorf Hbf: Parking, Taxis, WC.
Available at Düsseldorf Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Hbf.
Nearby hotels include Hotel Lindenhof, Hotel Batavia, Sir Astor, Lady Astor.
Düsseldorf Friedrichstadt is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Friedrichstadt has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Fu chu yuan, Taj Mahal, Hai Xian, To1980
Wi-Fi is available at Düsseldorf Friedrichstadt. ATMs are available at Düsseldorf Friedrichstadt.
Ticket office support is available at Düsseldorf Friedrichstadt. Information desks are available at Düsseldorf Friedrichstadt.
Luggage storage is available at Düsseldorf Friedrichstadt. Lost and found is available at the station.
Available at Düsseldorf Friedrichstadt: Parking, Taxis, WC.
Available at Düsseldorf Friedrichstadt: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Friedrichstadt.
Nearby hotels include Hotel Batavia, Hotel Ko, Hotel Burns, Hotel Düsseldorf Mitte.
Düsseldorf-Bilk is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf-Bilk has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Zur Pfeffermühle, Pizzeria Da Gino, Rohbau, Grindhouse Homemade Burgers
Wi-Fi is available at Düsseldorf-Bilk. ATMs are available at Düsseldorf-Bilk.
Ticket office support is available at Düsseldorf-Bilk. Information desks are available at Düsseldorf-Bilk.
Luggage storage is available at Düsseldorf-Bilk. Lost and found is available at the station.
Available at Düsseldorf-Bilk: Parking, Taxis, WC.
Available at Düsseldorf-Bilk: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf-Bilk.
Nearby hotels include Novum Hotel Maxim Düsseldorf City, Günnewig Hotel Esplanade, Novum Hotel Flora, Hotel Niku.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Here are some other resources that might have the information you need