- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$55
Average price
$63
Fastest journey
9 h 58 m
Average duration
11 h 9 m
Buses per day
26
Distance
553 km
The best way to find a cheap bus ticket from Düsseldorf to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Prague will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $55.
Of the 26 buses that leave Düsseldorf for Prague on Wed, Jul 15, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 15 the direct buses cover the 553 km distance in an average of 11 h 9 m but if you time it right, some buses will get you there in just 9 h 58 m .
On Wed, Jul 15 the slowest buses will take 11 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
(Amsterdam -> Prague)
FlixBus
FlixBus · FlixBus
FlixBus
FlixBusOmio recommends booking the train as it is the most popular option from Düsseldorf to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $36. For those with little time consider booking a flight which can get you there in 2h 7m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $36, and a flight costs an average of $75.
Distance: 343 miles (553 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$57 Average price Cheapest | $91 Average price | $226 Average price | $142 Average price (fuel + tolls) |
10h 36m Average total duration 10h 6m Onboard + 30m Additional time* | 9h 45m Average total duration 9h 15m Onboard + 30m Additional time* | 5h 7m Average total duration Fastest 2h 7m Onboard + 3h 0m Additional time* | 7h 48m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Düsseldorf to Prague:
A bus is $34 (€28) less than a train for this route with tickets for a train from Düsseldorf to Prague costing on average $91 (€75).
A bus is $169 (€139) less than a flight for this route with tickets for a flight from Düsseldorf to Prague costing on average $226 (€186).
Other travel options to Prague take longer:
Train takes on average 9h 15m.
Bus takes on average 10h 6m.
Tickets start at around $57 (€47) compared to roughly $142 (€117) in fuel and tolls — a saving of about $85 (€70). The journey takes 10h 6m versus 7h 48m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 01:05PM | Duration 11h35 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $58 |
Operator FlixBus | Departure Time 03:45AM | Arrival Time 05:35PM | Duration 13h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 02:10PM | Duration 7h10 | Departure days Fri | Cheapest price $88 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 07:10PM | Duration 11h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 07:50PM | Duration 12h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $59 |
Operator BlaBlaCar Bus | Departure Time 08:15AM | Arrival Time 09:45AM | Duration 25h30 | Departure days Mon, Fri | Cheapest price $176 |
Operator FlixBus | Departure Time 08:38AM | Arrival Time 10:25PM | Duration 13h47 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 04:40PM | Duration 7h40 | Departure days Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 09:10PM | Duration 11h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 09:27AM | Arrival Time 12:45AM | Duration 15h18 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 10:10AM | Arrival Time 05:00PM | Duration 6h50 | Departure days Fri | Cheapest price $61 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 12:45AM | Duration 14h30 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 07:50PM | Duration 8h20 | Departure days Wed | Cheapest price $88 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 07:20PM | Duration 7h20 | Departure days Mon | Cheapest price $62 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 07:50PM | Duration 6h50 | Departure days Thu | Cheapest price $58 |
Operator BlaBlaCar | Departure Time 01:20PM | Arrival Time 08:20PM | Duration 7h00 | Departure days Sat | Cheapest price $78 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:50AM | Duration 12h50 | Departure days Everyday | Cheapest price $56 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 07:00AM | Duration 14h15 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $61 |
Operator FlixBus | Departure Time 05:26PM | Arrival Time 07:15AM | Duration 13h49 | Departure days Sun | Cheapest price $88 |
Operator FlixBus | Departure Time 06:20PM | Arrival Time 06:55AM | Duration 12h35 | Departure days Everyday | Cheapest price $76 |
Operator RegioJet a.s. | Departure Time 06:50PM | Arrival Time 04:48AM | Duration 9h58 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $91 |
Operator BlaBlaCar | Departure Time 07:40PM | Arrival Time 03:10AM | Duration 7h30 | Departure days Tue | Cheapest price $90 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 11:20AM | Duration 12h45 | Departure days Everyday | Cheapest price $56 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 10:10AM | Duration 10h40 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 02:00PM | Duration 14h01 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $73 |
The table below shows live departures for Düsseldorf to Prague buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:00 PM Düsseldorf, ZOB am Hbf | 12h50 | 2:50 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:45 PM Düsseldorf, ZOB am Hbf | 14h15 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 6:20 PM Düsseldorf, ZOB am Hbf | 12h35 | 6:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:20 PM Düsseldorf, ZOB am Hbf | 14h10 | 8:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 6:20 PM Düsseldorf, ZOB am Hbf | 14h35 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 6:20 PM Düsseldorf, ZOB am Hbf | 13h10 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
(Amsterdam -> Prague) | 6:50 PM Düsseldorf, ZOB am Hbf | 9h58 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:35 PM Düsseldorf, ZOB am Hbf | 12h45 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 10:35 PM Düsseldorf, ZOB am Hbf | 11h30 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 11:30 PM Düsseldorf, ZOB am Hbf | 10h40 | 10:10 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:30 PM Düsseldorf, ZOB am Hbf | 12h00 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 11:59 PM Düsseldorf, ZOB am Hbf | 14h01 | 2:00 PM Prague, Central Train Station | 1 transfer | |
| Wednesday, July 15 | |||||
FlixBus · FlixBus | 1:30 AM Düsseldorf, ZOB am Hbf | 14h40 | 4:10 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus | 1:30 AM Düsseldorf, ZOB am Hbf | 12h00 | 1:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:45 AM Düsseldorf, ZOB am Hbf | 14h10 | 5:55 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:45 AM Düsseldorf, ZOB am Hbf | 13h50 | 5:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus | 7:15 AM Düsseldorf, ZOB am Hbf | 11h55 | 7:10 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 7:15 AM Düsseldorf, ZOB am Hbf | 15h10 | 10:25 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus | 7:15 AM Düsseldorf, ZOB am Hbf | 12h45 | 8:00 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus | 7:30 AM Düsseldorf, ZOB am Hbf | 11h40 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 7:30 AM Düsseldorf, ZOB am Hbf | 12h05 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 8:38 AM Düsseldorf Hbf | 13h47 | 10:25 PM Praha, Černý Most | 1 transfer | |
FlixBus | 9:15 AM Düsseldorf, ZOB am Hbf | 11h55 | 9:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 9:15 AM Düsseldorf, ZOB am Hbf | 12h15 | 9:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus · FlixBus | 9:27 AM Düsseldorf Hbf | 15h18 | 12:45 AM Prague, Central Train Station | 2 transfers | |
FlixTrain+ FlixBus · FlixBus | 9:27 AM Düsseldorf Hbf | 15h03 | 12:30 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 10:15 AM Düsseldorf, ZOB am Hbf | 14h30 | 12:45 AM Prague, Central Train Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Buses from Düsseldorf to Prague run on average 23 times per day, taking around 10h 6m. Cheap bus tickets for this journey start at $36 (€30) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 343 miles (553 km) distance in 9h 55m.
Distance 343 miles (553 km) |
Average bus duration 10h 6m |
Cheapest ticket price $36 (€30) |
Buses per day 23 |
Direct buses 6 |
Fastest bus 9h 55m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Mon |
Best time to book 70 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Düsseldorf to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need