The cheapest and fastest buses from Düsseldorf to Prague
Cheapest price
$49
Average price
$56
Fastest journey
9 h 55 m
Average duration
10 h 46 m
Buses per day
21
Distance
553 km
The best way to find a cheap bus ticket from Düsseldorf to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Prague will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $49.
Of the 21 buses that leave Düsseldorf for Prague on Mon, Mar 02, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 02 the direct buses cover the 553 km distance in an average of 10 h 46 m but if you time it right, some buses will get you there in just 9 h 55 m .
On Mon, Mar 02 the slowest buses will take 11 h 49 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
(Amsterdam -> Prague)
(Amsterdam -> Prague)
FlixBus · FlixBus
FlixBus · FlixBus
(Amsterdam -> Prague)
(Amsterdam -> Prague)
FlixBus
FlixBus · FlixBus
FlixTrain+
FlixBusTravel Information
Compare train, bus, and flight for Düsseldorf to Prague
Omio recommends booking the train as it is the most popular option from Düsseldorf to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a flight which can get you there in 2h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $55.
Distance: 343 miles (553 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$60 Average price Cheapest | $93 Average price | $192 Average price |
10h 24m Average total duration 9h 54m Onboard + 30m Additional time* | 9h 50m Average total duration 9h 20m Onboard + 30m Additional time* | 5h 0m Average total duration Fastest 2h 0m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Düsseldorf to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 01:30PM | Duration 12h00 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 03:45AM | Arrival Time 05:55PM | Duration 14h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 07:10PM | Duration 11h55 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 07:35PM | Duration 12h05 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 08:31AM | Arrival Time 08:20PM | Duration 11h49 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 08:38AM | Arrival Time 08:20PM | Duration 11h42 | Departure days Sat | Cheapest price $64 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 09:30PM | Duration 12h15 | Departure days Thu, Fri, Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 09:27AM | Arrival Time 12:25AM | Duration 14h58 | Departure days Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 12:25AM | Duration 14h10 | Departure days Mon, Tue, Fri, Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 12:25AM | Duration 13h55 | Departure days Mon, Sun | Cheapest price $58 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:50AM | Duration 12h50 | Departure days Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 07:00AM | Duration 14h15 | Departure days Mon, Fri, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 06:55AM | Duration 13h35 | Departure days Wed | Cheapest price $70 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 06:55AM | Duration 13h15 | Departure days Mon, Tue | Cheapest price $53 |
Operator FlixBus | Departure Time 06:20PM | Arrival Time 07:30AM | Duration 13h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $54 |
Operator Regiojet | Departure Time 06:50PM | Arrival Time 04:45AM | Duration 9h55 | Departure days Everyday | Cheapest price $42 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 08:55AM | Duration 11h55 | Departure days Mon, Sat, Sun | Cheapest price $54 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 12:40PM | Duration 15h00 | Departure days Tue, Wed | Cheapest price $57 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 12:10PM | Duration 13h35 | Departure days Everyday | Cheapest price $53 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 10:10AM | Duration 10h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 02:00PM | Duration 14h01 | Departure days Everyday | Cheapest price $54 |
Live departures
Düsseldorf to Prague bus times
The table below shows live departures for Düsseldorf to Prague buses for today, Sunday, March 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:45 AM Düsseldorf, ZOB am Hbf | 13h50 | 4:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus | 2:45 AM Düsseldorf, ZOB am Hbf | 14h10 | 4:55 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 6:15 AM Düsseldorf, ZOB am Hbf | 11h55 | 6:10 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 6:30 AM Düsseldorf, ZOB am Hbf | 11h40 | 6:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus · FlixBus | 6:30 AM Düsseldorf, ZOB am Hbf | 12h20 | 6:50 PM Praha, Zličín | 1 transfer | |
FlixBus | 6:30 AM Düsseldorf, ZOB am Hbf | 12h05 | 6:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 7:31 AM Düsseldorf Hbf | 11h49 | 7:20 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 8:15 AM Düsseldorf, ZOB am Hbf | 12h15 | 8:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 8:15 AM Düsseldorf, ZOB am Hbf | 11h55 | 8:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus · FlixBus | 9:30 AM Düsseldorf, ZOB am Hbf | 13h55 | 11:25 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:00 PM Düsseldorf, ZOB am Hbf | 12h50 | 1:50 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 3:45 PM Düsseldorf, ZOB am Hbf | 14h15 | 6:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 5:20 PM Düsseldorf, ZOB am Hbf | 12h35 | 5:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:20 PM Düsseldorf, ZOB am Hbf | 13h10 | 6:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:20 PM Düsseldorf, ZOB am Hbf | 14h10 | 7:30 AM Praha, Zličín | 2 transfers | |
(Amsterdam -> Prague) | 5:50 PM Düsseldorf, ZOB am Hbf | 9h55 | 3:45 AM Prague, Central Train Station | 0 transfersDirect | |
(Amsterdam -> Prague) | 5:50 PM Düsseldorf, ZOB am Hbf | 9h58 | 3:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 8:00 PM Düsseldorf, ZOB am Hbf | 11h55 | 7:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 9:35 PM Düsseldorf, ZOB am Hbf | 11h30 | 9:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 9:35 PM Düsseldorf, ZOB am Hbf | 13h35 | 11:10 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 10:30 PM Düsseldorf, ZOB am Hbf | 10h40 | 9:10 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:30 PM Düsseldorf, ZOB am Hbf | 12h30 | 11:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 10:59 PM Düsseldorf, ZOB am Hbf | 14h01 | 1:00 PM Prague, Central Train Station | 1 transfer | |
| Monday, March 2 | |||||
FlixBus · FlixBus | 12:30 AM Düsseldorf, ZOB am Hbf | 14h40 | 3:10 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus | 12:30 AM Düsseldorf, ZOB am Hbf | 12h00 | 12:30 PM Praha, ÚAN Florenc | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Düsseldorf to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Düsseldorf to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Düsseldorf to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Düsseldorf to Prague.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Düsseldorf to Prague.
ReviewsReviews for the bus trip from Düsseldorf to Prague

Journey information
Overview: Bus from Düsseldorf to Prague
Buses from Düsseldorf to Prague run on average 23 times per day, taking around 9h 54m. Cheap bus tickets for this journey start at $38 (€30) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 343 miles (553 km) distance in 9h 58m.
Distance 343 miles (553 km) |
Average bus duration 9h 54m |
Cheapest ticket price $38 (€30) |
Buses per day 23 |
Direct buses 6 |
Fastest bus 9h 58m |
First bus 00:10 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar, Infobus from Düsseldorf to PragueYou can travel by bus between Düsseldorf to Prague with FlixBus, BlaBlaCar, Infobus for as low as $38 (€30). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar
FAQs: Bus from Düsseldorf to Prague
Find answers to the most common questions about traveling from Düsseldorf to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Düsseldorf to Prague
- 05:00-23:00
- Free Wi-Fi
- Cafeteria im ZOB (in the station)
- Brauerei Schumacher (0.5 km)
- Pizzeria Trattoria Romantica (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 725, 738, 752, 754, 834 Metro: U75, U78, U79 Train: S1, S6, S11
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Düsseldorf
More options for your journey from Düsseldorf to Prague
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