- Must visit
Kunstpalast
Leading contemporary art museum in Ehrenhof. It is essential for modern and postwar art, with major temporary exhibitions and strong collections.
Cheapest price on Sep 23
€38
Average ticket price on Sep 23
€110
Fastest journey on Sep 23
8 h 37 m
Average journey duration on Sep 23
8 h 44 m
Trains on Sep 23
20
Distance
553 km
The best way to find a cheap train ticket from Prague to Düsseldorf is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Düsseldorf will cost around €110 if you buy it on the day, but the cheapest tickets can be found for only €38.
It's difficult to get from Prague to Düsseldorf without transferring at least once.
FlixBus+
FlixTrain
FlixBus · FlixBus+
FlixTrain
EC 458 · ICE 699 · IC 60402
EX 354 · 3576 · ICE 526
EX 352 · 3580 · ICE 522 · 26843
RJ 382 · ICE 546
RJ 384 · ICE 640
RJ 176 · ICE 544
RJ 178 · ICE 548
EX 362 · 3560 · ICE 722Omio recommends booking the flight as it is the most popular option from Prague to Düsseldorf among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €50 For those with little time, consider booking a flight, which has an average total journey time of 4h 52m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €50, while a flight costs an average of €337.
Distance: 343 miles (553 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
€139 Average price | €337 Average price | €50 Average price Cheapest | €117 Average price (fuel + tolls) |
9h 21m Average total duration 8h 51m Onboard + 30m Additional time* | 4h 52m Average total duration Fastest 2h 52m Onboard + 2h 0m Additional time* | 11h 42m Average total duration 11h 12m Onboard + 30m Additional time* | 6h 53m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions | 0.6 - 1.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Düsseldorf:
A bus is €88 less than a train for this route with tickets for a train from Prague to Düsseldorf costing on average €139.
A bus is €287 less than a flight for this route with tickets for a flight from Prague to Düsseldorf costing on average €337.
Other travel options to Düsseldorf take longer:
Train takes on average 8h 51m.
Bus takes on average 11h 12m.
Tickets start at around €139 compared to roughly €117 in fuel and tolls — a saving of about €-21.35. The journey takes 8h 51m versus 6h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Prague to Düsseldorf trains for today, Tuesday, September 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
EX 350 · ICE 618 | On time 5:35 PM Prague hlavní nádraží | 12h57 | 6:32 AM Düsseldorf Hbf | 1 transfer | |
EC 458 · ICE 699 · IC 60402 | On time 6:31 PM Prague hlavní nádraží | 11h44 | 6:15 AM Düsseldorf Hbf | 2 transfers | |
R 676 · Bus 28015 · S1 · 16538 | 6:47 PM Prague hlavní nádraží | 14h45 | 9:32 AM Düsseldorf Hbf | 6 transfers | |
R 676 · Os 28015 · S1 · 16536 | On time 6:47 PM Prague hlavní nádraží | 14h25 | 9:12 AM Düsseldorf Hbf | 7 transfers | |
R 676 · Bus 28015 · S1 · 16538 | On time 6:47 PM Prague hlavní nádraží | 14h49 | 9:36 AM Düsseldorf Hbf | 5 transfers | |
EC 460 · EC 430 · S15 · ICE 654 | 6:49 PM Prague hlavní nádraží | 16h29 | 11:18 AM Düsseldorf Hbf | 4 transfers | |
RJ 170 · IC 1910 · ICE 593 · ICE 728 | 8:47 PM Prague hlavní nádraží | 14h50 | 11:37 AM Düsseldorf Hbf | 3 transfers | |
| Wednesday, September 23 | |||||
FlixBus+ FlixTrain | 2:00 AM Prague, Central Train Station | 11h14 | 1:14 PM Düsseldorf Hbf | 1 transfer | |
EX 362 · 3560 · ICE 722 | On time 5:35 AM Prague hlavní nádraží | 9h01 | 2:36 PM Düsseldorf Hbf | 2 transfers | |
RJ 384 · ICE 640 | On time 6:31 AM Prague hlavní nádraží | 8h40 | 3:11 PM Düsseldorf Hbf | 1 transfer | |
R 696 · Os 28003 · S1 · ICE 1650 | On time 6:47 AM Prague hlavní nádraží | 9h45 | 4:32 PM Düsseldorf Hbf | 5 transfers | |
EX 360 · 3564 · ICE 628 | On time 7:35 AM Prague hlavní nádraží | 9h05 | 4:40 PM Düsseldorf Hbf | 2 transfers | |
RJ 178 · ICE 548 | On time 8:31 AM Prague hlavní nádraží | 8h41 | 5:12 PM Düsseldorf Hbf | 1 transfer | |
R 692 · Os 28005 · S1 · ICE 1558 | 8:47 AM Prague hlavní nádraží | 9h45 | 6:32 PM Düsseldorf Hbf | 5 transfers | |
FlixBus · FlixBus+ FlixTrain | 9:30 AM Praha, ÚAN Florenc | 11h55 | 9:25 PM Düsseldorf Hbf | 2 transfers | |
EX 358 · 3568 · ICE 624 | On time 9:35 AM Prague hlavní nádraží | 9h01 | 6:36 PM Düsseldorf Hbf | 2 transfers | |
RJ 382 · ICE 546 | On time 10:31 AM Prague hlavní nádraží | 8h37 | 7:08 PM Düsseldorf Hbf | 1 transfer | |
R 690 · Os 28007 · S1 · ICE 1556 | 10:47 AM Prague hlavní nádraží | 9h45 | 8:32 PM Düsseldorf Hbf | 5 transfers | |
EX 356 · 3572 · ICE 620 | On time 11:35 AM Prague hlavní nádraží | 9h02 | 8:37 PM Düsseldorf Hbf | 2 transfers | |
RJ 176 · ICE 544 | On time 12:31 PM Prague hlavní nádraží | 8h41 | 9:12 PM Düsseldorf Hbf | 1 transfer | |
R 688 · Os 28009 · S1 · ICE 1554 | 12:47 PM Prague hlavní nádraží | 9h45 | 10:32 PM Düsseldorf Hbf | 5 transfers | |
EX 354 · 3576 · ICE 526 | On time 1:35 PM Prague hlavní nádraží | 9h01 | 10:36 PM Düsseldorf Hbf | 2 transfers | |
RJ 174 · ICE 542 | On time 2:41 PM Prague-Holešovice | 9h06 | 11:47 PM Düsseldorf Hbf | 1 transfer | |
EX 352 · 3580 · ICE 522 · 26843 | On time 3:35 PM Prague hlavní nádraží | 9h45 | 1:20 AM Düsseldorf Hbf | 3 transfers | |
EX 352 · 3580 · ICE 522 · ICE 920 | On time 3:35 PM Prague hlavní nádraží | 11h06 | 2:41 AM Düsseldorf Hbf | 3 transfers | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Prague to Düsseldorf run on average 13 times per day, taking around 8h 51m. Cheap train tickets for this journey start at €30 but you can travel from only €27 by bus.
The earliest train runs at 00:01, the last at 23:58. The fastest train covers the 343 miles (553 km) distance in 7h 48m.
Distance 343 miles (553 km) |
Average train duration 8h 51m |
Cheapest ticket price €30 |
Trains per day 13 |
Fastest train 7h 48m |
First train 12:01 AM |
Last train 11:58 PM |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Mon |
Best time to book 42 days |
Discover the best of Düsseldorf — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Düsseldorf trip today.
Leading contemporary art museum in Ehrenhof. It is essential for modern and postwar art, with major temporary exhibitions and strong collections.
Major state art collection focused on twentieth-century masters. It is a top stop for Klee, Picasso, and European modernism.
Underground exhibition building in Grabbeplatz for postwar and contemporary art. It is known for ambitious rotating international shows.
The historic old town with lanes, churches, and squares near the Rhine. It is the classic place to experience Düsseldorf’s heritage on foot.
Elegant boulevard known for luxury shopping, canal views, and city prestige. It is Düsseldorf’s signature street and a classic urban promenade.
Wide Rhine riverside walk with skyline views, steps, and event spaces. It is one of the city’s best areas for strolling and sunset photos.
Marinated herring fillets in a creamy sour sauce, often served with apples, onions and potatoes. A classic Rhineland tavern dish.
Slow-cooked beef roast in a dark sweet-sour gravy with raisins and beet syrup. One of the Rhineland’s most traditional celebratory dishes.
Black pudding from the Rhineland, usually pan-fried and served with mashed potatoes, sauerkraut or onions. A deeply local comfort food.
Refined fine-dining restaurant with modern French-influenced cuisine, elegant service and one of Düsseldorf’s top gastronomic reputations.
Traditional brewery restaurant famous for Füchschen Alt and robust Düsseldorf specialties in a convivial local setting.
Historic Altstadt brewery serving fresh Altbier and classic Rhineland dishes in a lively, traditional beer-hall setting.
Moderate for Germany: hotels can be pricey during fairs, but dining and local transit are manageable for most tourists.
Service is usually not included. Round up or tip 5-10% in restaurants, round up taxi fares, and leave small change at cafes.
Traveling between Prague and Düsseldorf is a seamless experience, thanks to reliable train connections provided by Deutsche Bahn and FlixTrain. With comfortable seating and scenic views along the route, you can enjoy an efficient journey that typically takes around 8 hours. Whether you're heading for business or leisure, these providers ensure a smooth ride through picturesque landscapes of Central Europe.
The train journey from Prague to Düsseldorf takes approximately 9 hours and 12 minutes, with one connection required. There are no direct trains available for this route, and the average layover time is about 1 hour and 15 minutes.
The first daily train journey from Prague to Düsseldorf departs at 05:10, providing an early start for travelers eager to explore. The last departure of the day is scheduled for 21:31, allowing visitors ample time to enjoy their evening in either city before heading out.
The cheapest ticket price for the train connection between Prague and Düsseldorf is €53. The average ticket price tends to be around €126, making it a good option to book in advance or look out for special deals.
Welcome to Düsseldorf! Our first stop is the Rheinturm, or Rhine Tower, which was completed in 1981 and stands as a symbol of modern architecture in the city. This iconic structure not only offers breathtaking panoramic views from its observation deck but also features an impressive light installation that illuminates the skyline at night.
Next, we’ll stroll along Königsallee, affectionately known as "Kö," which has been a fashionable shopping destination since the early 19th century. Its significance lies in being one of Europe’s most luxurious boulevards lined with high-end boutiques and elegant cafes; it perfectly embodies Düsseldorf's reputation for style and sophistication. The unique feature here is its picturesque canal running through the center, creating a serene atmosphere amidst bustling retail activity.
Finally, let’s explore MedienHafen, once an industrial port transformed into a vibrant media hub starting in the late 20th century. This area signifies innovation and creativity with its striking contemporary buildings designed by renowned architects like Frank Gehry; it's where art meets commerce seamlessly. What makes MedienHafen truly special are its lively waterfront promenades filled with trendy restaurants and bars offering stunning views of both historic docks and modern structures alike.
Find answers to the most common questions about traveling from Prague to Düsseldorf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Düsseldorf, this guide helps you travel smarter and with confidence.

Most Prague to Düsseldorf trains use the Praha hlavní nádraží to Düsseldorf Hbf station pair, with some services arriving at Düsseldorf Friedrichstadt. Use this guide to compare Prague and Düsseldorf train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Düsseldorf Hbf is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Zaxopondeiva Cafe, Lauren's Cafe, China Imbiss, Fu chu yuan
Wi-Fi is available at Düsseldorf Hbf. ATMs are available at Düsseldorf Hbf.
Ticket office support is available at Düsseldorf Hbf. Information desks are available at Düsseldorf Hbf.
Luggage storage is available at Düsseldorf Hbf. Lost and found is available at the station.
Available at Düsseldorf Hbf: Parking, Taxis, WC.
Available at Düsseldorf Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Hbf.
Nearby hotels include Hotel Lindenhof, Hotel Batavia, Sir Astor, Lady Astor.
Düsseldorf Friedrichstadt is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf Friedrichstadt has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Fu chu yuan, Taj Mahal, Hai Xian, To1980
Wi-Fi is available at Düsseldorf Friedrichstadt. ATMs are available at Düsseldorf Friedrichstadt.
Ticket office support is available at Düsseldorf Friedrichstadt. Information desks are available at Düsseldorf Friedrichstadt.
Luggage storage is available at Düsseldorf Friedrichstadt. Lost and found is available at the station.
Available at Düsseldorf Friedrichstadt: Parking, Taxis, WC.
Available at Düsseldorf Friedrichstadt: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf Friedrichstadt.
Nearby hotels include Hotel Batavia, Hotel Ko, Hotel Burns, Hotel Düsseldorf Mitte.
Düsseldorf-Bilk is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf-Bilk has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Zur Pfeffermühle, Pizzeria Da Gino, Rohbau, Grindhouse Homemade Burgers
Wi-Fi is available at Düsseldorf-Bilk. ATMs are available at Düsseldorf-Bilk.
Ticket office support is available at Düsseldorf-Bilk. Information desks are available at Düsseldorf-Bilk.
Luggage storage is available at Düsseldorf-Bilk. Lost and found is available at the station.
Available at Düsseldorf-Bilk: Parking, Taxis, WC.
Available at Düsseldorf-Bilk: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Düsseldorf-Bilk.
Nearby hotels include Novum Hotel Maxim Düsseldorf City, Günnewig Hotel Esplanade, Novum Hotel Flora, Hotel Niku.
Here are some other resources that might have the information you need