- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey on Place des Terreaux, known for strong collections from antiquity to modern art.
Cheapest price
$235
Average price
$273
Fastest journey
7 h 46 m
Average duration
8 h 35 m
Trains per day
6
Distance
625 km
The best way to find a cheap train ticket from Düsseldorf to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Lyon will cost around $273 if you buy it on the day, but the cheapest tickets can be found for only $235.
It's difficult to get from Düsseldorf to Lyon without transferring at least once.
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6685
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6615
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6613
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6621Omio recommends booking the bus as it is the most popular option from Düsseldorf to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $46. For those with little time consider booking a flight which can get you there in 2h 21m. The ticket price range depends on the travel mode: a bus costs an average of $46, and a flight costs an average of $81.
Distance: 388 miles (625 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$265 Average price | $71 Average price Cheapest | $299 Average price | $192 Average price (fuel + tolls) |
6h 51m Average total duration 6h 21m Onboard + 30m Additional time* | 12h 40m Average total duration 12h 10m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* | 8h 29m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Düsseldorf to Lyon:
A bus is $194 (€157) less than a train for this route with tickets for a train from Düsseldorf to Lyon costing on average $265 (€214).
A bus is $228 (€185) less than a flight for this route with tickets for a flight from Düsseldorf to Lyon costing on average $299 (€242).
Other travel options to Lyon take longer:
Train takes on average 6h 21m.
Bus takes on average 12h 10m.
You'll arrive about 2h 8m sooner (6h 21m by train vs 8h 29m by car). Tickets start at around $265 (€214) compared to roughly $192 (€155) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Düsseldorf to Lyon trains for today, Tuesday, June 16. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9414+ 6613 | 6:09 AM Düsseldorf Hbf | 7h47 | 1:56 PM Lyon Part Dieu | 1 transfer | |
9414+ 6685 | 6:09 AM Düsseldorf Hbf | 8h47 | 2:56 PM Lyon Part Dieu | 1 transfer | |
9414+ 6615 | 6:09 AM Düsseldorf Hbf | 8h47 | 2:56 PM Lyon Part Dieu | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Düsseldorf to Lyon run on average 3 times per day, taking around 6h 21m. Cheap train tickets for this journey start at $83 (€67) but you can travel from only $46 (€37) by bus.
The earliest train runs at 00:08, the last at 23:55. The fastest train covers the 388 miles (625 km) distance in 6h 46m.
Distance 388 miles (625 km) |
Average train duration 6h 21m |
Cheapest ticket price $83 (€67) |
Trains per day 3 |
Fastest train 6h 46m |
First train 12:08 AM |
Last train 11:55 PM |
Cheapest Month Jan |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 14 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey on Place des Terreaux, known for strong collections from antiquity to modern art.
Excellent museum on Roman Lyon with mosaics, inscriptions, and artifacts beside the ancient theaters on Fourvière hill.
Striking science and society museum at the meeting of the Rhône and Saône, famous for immersive displays and architecture.
The city's atmospheric old quarter with Renaissance lanes, traboules, courtyards, and a strong UNESCO heritage feel.
One of Europe's largest open squares and a key central meeting point in Lyon's Presqu'île.
Large urban park with lake, botanical spaces, greenhouses, and broad paths for walking and relaxing.
Light dumplings traditionally made with pike and baked in a rich Nantua crayfish sauce, a classic specialty of Lyonnais cuisine.
A warm salad of frisee lettuce, lardons, croutons, and a poached egg, emblematic of Lyon's hearty bouchon cooking.
Pork sausage baked inside a soft brioche loaf, a festive and traditional Lyonnais dish often served in bouchons.
An iconic fine-dining restaurant with deep Lyon culinary heritage, serving elegant cuisine in a prestigious setting.
A respected modern bouchon offering refined takes on Lyonnais classics in a warm and polished setting.
A historic bouchon known for classic Lyonnais dishes, convivial service, and a traditional, bustling atmosphere.
Moderate by French standards: bakeries and lunch deals are good value, while central hotels and dinner spots cost more.
Service is included by law. Rounding up or leaving 5-10% for very good restaurant service is appreciated, not required. Round up taxis; small change is fine in cafés and bars.
Official public transport app
Lyon Part-Dieu -> Bellecour, Lyon
Find answers to the most common questions about traveling from Düsseldorf to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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