- Must visit
Mint Museum Uptown
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
The best way to find a cheap bus ticket from Wilmington, DE to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wilmington, DE to Charlotte, NC will cost around €76 if you buy it on the day, but the cheapest tickets can be found for only €71.
It's difficult to get from Wilmington, DE to Charlotte, NC without transferring at least once.
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Buses from Wilmington, DE to Charlotte, NC run on average 6 times per day, taking around 12h 20m. Cheap bus tickets for this journey start at €51 but you can travel from only €39 by flight.
The earliest bus runs at 01:05, the last at 23:55. The fastest bus covers the 426 miles (686 km) distance in 10h 10m.
Distance 426 miles (686 km) |
Average bus duration 12h 20m |
Cheapest ticket price €51 |
Buses per day 6 |
Fastest bus 10h 10m |
First bus 1:05 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 14 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Wilmington, DE to Charlotte, NC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 12:20PM | Duration 11h25 | Departure days Mon, Tue, Thu | Cheapest price €77 |
Operator Greyhound | Departure Time 01:25AM | Arrival Time 01:30PM | Duration 12h05 | Departure days Mon, Thu, Sat, Sun | Cheapest price €85 |
Operator Greyhound | Departure Time 01:45AM | Arrival Time 05:55PM | Duration 16h10 | Departure days Mon, Tue, Thu | Cheapest price €79 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 02:30PM | Duration 12h05 | Departure days Mon, Thu, Sat, Sun | Cheapest price €90 |
Operator FlixBus | Departure Time 03:40AM | Arrival Time 09:20PM | Duration 17h40 | Departure days Mon | Cheapest price €131 |
Operator Greyhound | Departure Time 05:45AM | Arrival Time 02:10AM | Duration 20h25 | Departure days Fri | Cheapest price €110 |
Operator Greyhound | Departure Time 06:45AM | Arrival Time 03:10AM | Duration 20h25 | Departure days Wed, Fri, Sun | Cheapest price €111 |
Operator FlixBus | Departure Time 11:20AM | Arrival Time 12:45AM | Duration 13h25 | Departure days Mon, Thu | Cheapest price €126 |
Operator Greyhound | Departure Time 01:50PM | Arrival Time 04:10AM | Duration 14h20 | Departure days Mon, Tue, Thu | Cheapest price €80 |
Operator FlixBus | Departure Time 05:50PM | Arrival Time 10:50AM | Duration 17h00 | Departure days Wed, Sat, Sun | Cheapest price €97 |
Operator FlixBus | Departure Time 06:50PM | Arrival Time 11:50AM | Duration 17h00 | Departure days Wed, Sat | Cheapest price €124 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 09:05AM | Duration 12h55 | Departure days Mon, Tue, Thu | Cheapest price €71 |
Operator Greyhound | Departure Time 09:45PM | Arrival Time 05:55PM | Duration 20h10 | Departure days Mon, Tue | Cheapest price €71 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 05:40PM | Duration 19h55 | Departure days Thu | Cheapest price €81 |
The table below shows live departures for Wilmington, DE to Charlotte, NC buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 12:55 AM Wilmington, Amtrak Station @ ML King-French | 11h25 | 12:20 PM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
· · | 1:45 AM Wilmington, Amtrak Station @ ML King-French | 16h10 | 5:55 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
FlixBus+![]() | 3:40 AM Wilmington, Amtrak Station @ ML King-French | 17h40 | 9:20 PM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 11:20 AM Wilmington, Amtrak Station @ ML King-French | 13h25 | 12:45 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
· | 1:50 PM Wilmington, Amtrak Station @ ML King-French | 14h20 | 4:10 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
· | 8:10 PM Wilmington, Amtrak Station @ ML King-French | 12h55 | 9:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Charlotte, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charlotte, NC trip today.
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
Leading center for African American arts and culture, featuring exhibitions, performances, and powerful stories from Charlotte and beyond.
Regional science museum with hands-on exhibits, live demonstrations, and an IMAX Dome. Great for families and curious adults alike.
Charlotte's central business district mixes museums, plazas, public art, and skyline views. Essential for first-time visitors exploring the city core.
Creative historic district packed with murals, music venues, design shops, and converted mills. Ideal for art, walking, and local culture.
Trendy neighborhood known for rail-trail walking, street art, breweries, and restored industrial spaces. One of Charlotte's liveliest areas.
Slow-smoked chopped or pulled pork with a tangy vinegar sauce, a Carolina barbecue staple widely loved across Charlotte.
Smoky pit-cooked pork shoulder finished with mustard-based sauce, reflecting South Carolina influence common in Charlotte.
Deep-fried catfish, often served with hush puppies and slaw. It is a classic Southern comfort dish popular in the Charlotte region.
Historic barbecue spot famed for Carolina chopped pork, red slaw, and old-school Southern atmosphere.
Lively Southern dining room serving fried chicken, biscuits, shrimp and grits, and regional cocktails in South End.
Refined Southern restaurant in Uptown known for shrimp and grits, local ingredients, and an elegant modern setting.
Moderate for a major U.S. city. Hotels and dining are mid-priced, transit is affordable, and attractions often cost less than in larger hubs like New York or San Francisco.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charlotte, NC.
Find answers to the most common questions about traveling from Wilmington, DE to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

Most Wilmington, DE to Charlotte, NC buses use the Wilmington, Amtrak Station @ ML King-French to Charlotte, W 4th St (Greyhound Bus Station) station pair. Use this guide to compare Wilmington, DE and Charlotte, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charlotte, W 4th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Charlotte, W 4th St (Greyhound Bus Station). ATMs are available at Charlotte, W 4th St (Greyhound Bus Station).
Ticket office support is available at Charlotte, W 4th St (Greyhound Bus Station).
Available at Charlotte, W 4th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charlotte, W 4th St (Greyhound Bus Station): The station is wheelchair accessible.
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