Travel Information
Compare train, bus, and flight for Wilmington, DE to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Wilmington, DE to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €103. For those with little time consider booking a flight which can get you there in 8h 11m. The ticket price range depends on the travel mode: a bus costs an average of €103, and a train costs an average of €162.
Distance: 648 miles (1044 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€120 Average price Cheapest | €204 Average price | €144 Average price |
20h 45m Average total duration 20h 15m Onboard + 30m Additional time* | 26h 46m Average total duration 26h 16m Onboard + 30m Additional time* | 11h 11m Average total duration Fastest 8h 11m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Wilmington, DE to Chicago, IL bus times
The table below shows live departures for Wilmington, DE to Chicago, IL buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:50 PM Wilmington, DE | 25h40 | 7:30 PM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Wilmington, DE to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Wilmington, DE to Chicago, IL
Buses from Wilmington, DE to Chicago, IL run on average 4 times per day, taking around 20h 15m. Cheap bus tickets for this journey start at $129 (€103) but you can travel from only $104 (€83) by flight.
The earliest bus runs at 03:30, the last at 23:15. The fastest bus covers the 648 miles (1044 km) distance in 22h 10m.
Distance 648 miles (1044 km) |
Average bus duration 20h 15m |
Cheapest ticket price $129 (€103) |
Buses per day 4 |
Fastest bus 22h 10m |
First bus 03:30 |
Last bus 23:15 |
Bus providers: Greyhound from Wilmington, DE to Chicago, ILYou can travel by bus between Wilmington, DE to Chicago, IL with Greyhound for as low as $104 (€83). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Wilmington, DE to Chicago, IL
Find answers to the most common questions about traveling from Wilmington, DE to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Wilmington, DE to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Wilmington, DE to Chicago, IL
Most popular bus connections from Wilmington, DE
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