- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Cheapest price
€159
Average price
€159
Fastest journey
23 h 40 m
Average duration
23 h 40 m
Buses per day
1
Distance
1044 km
The best way to find a cheap bus ticket from Wilmington, DE to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wilmington, DE to Chicago, IL will cost around €159 if you buy it on the day, but the cheapest tickets can be found for only €159.
Of the 1 buses that leave Wilmington, DE for Chicago, IL on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 1044 km distance in an average of 23 h 40 m but if you time it right, some buses will get you there in just 23 h 40 m .
On Wed, Aug 05 the slowest buses will take 23 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Wilmington, DE to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €132. For those with little time consider booking a flight which can get you there in 5h 34m. The ticket price range depends on the travel mode: a bus costs an average of €132, and a train costs an average of €111.
Distance: 648 miles (1044 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€162 Average price Cheapest | €232 Average price | €172 Average price | €231 Average price (fuel + tolls) |
21h 28m Average total duration 20h 58m Onboard + 30m Additional time* | 20h 7m Average total duration 19h 37m Onboard + 30m Additional time* | 8h 34m Average total duration Fastest 5h 34m Onboard + 3h 0m Additional time* | 11h 40m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Wilmington, DE to Chicago, IL:
A bus is €10 less than a flight for this route with tickets for a flight from Wilmington, DE to Chicago, IL costing on average €172.
A bus is €70 less than a train for this route with tickets for a train from Wilmington, DE to Chicago, IL costing on average €232.
Other travel options to Chicago, IL take longer:
Train takes on average 19h 37m.
Bus takes on average 20h 58m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:25AM | Arrival Time 01:05AM | Duration 23h40 | Departure days Wed, Thu | Cheapest price €159 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 02:00PM | Duration 35h35 | Departure days Sat | Cheapest price €175 |
Operator Greyhound USA | Departure Time 06:00AM | Arrival Time 06:10AM | Duration 24h10 | Departure days Sun | Cheapest price €132 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 08:00AM | Duration 23h00 | Departure days Mon, Thu, Sat | Cheapest price €96 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 06:10AM | Duration 21h10 | Departure days Mon, Thu, Sat | Cheapest price €77 |
Operator Greyhound | Departure Time 11:20AM | Arrival Time 01:45PM | Duration 27h25 | Departure days Mon, Thu, Sat | Cheapest price €73 |
Operator Greyhound USA | Departure Time 01:50PM | Arrival Time 10:00AM | Duration 20h10 | Departure days Sun | Cheapest price €185 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 08:00AM | Duration 36h50 | Departure days Mon, Thu, Sat | Cheapest price €82 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 06:25PM | Duration 21h25 | Departure days Fri | Cheapest price €141 |
Operator Greyhound USA | Departure Time 09:25PM | Arrival Time 08:05PM | Duration 22h40 | Departure days Sun | Cheapest price €177 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 06:55PM | Duration 22h10 | Departure days Mon, Thu, Sat | Cheapest price €90 |
The table below shows live departures for Wilmington, DE to Chicago, IL buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus+ · | 8:10 PM Wilmington, Amtrak Station @ ML King-French | 36h50 | 8:00 AM Chicago, Union Station (Amtrak), IL | 3 transfers | |
| Tuesday, August 4 | |||||
![]() | 1:25 AM Wilmington, DE | 23h40 | 1:05 AM Chicago, IL | 0 transfersDirect | |
| Monday, August 3 | |||||
+ FlixBus | 9:45 PM Wilmington, Amtrak Station @ ML King-French | 22h10 | 6:55 PM Chicago, Greyhound Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Wilmington, DE to Chicago, IL run on average 6 times per day, taking around 20h 58m. Cheap bus tickets for this journey start at €132 but you can travel from only €111 by train.
The earliest bus runs at 03:30, the last at 23:35. The fastest bus covers the 648 miles (1044 km) distance in 21h 25m.
Distance 648 miles (1044 km) |
Average bus duration 20h 58m |
Cheapest ticket price €132 |
Buses per day 6 |
Fastest bus 21h 25m |
First bus 3:30 AM |
Last bus 11:35 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 49 days |
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from Wilmington, DE to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Wilmington, DE to Chicago, IL buses use the Wilmington, Amtrak Station @ ML King-French to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Wilmington, DE and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need