- Must visit
Art Institute Of Chicago
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Cheapest price
$208
Average price
$215
Fastest journey
23 h 40 m
Average duration
1 d 1 h 40 m
Buses per day
2
Distance
1044 km
The best way to find a cheap bus ticket from Wilmington, DE to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wilmington, DE to Chicago, IL will cost around $215 if you buy it on the day, but the cheapest tickets can be found for only $208.
Of the 2 buses that leave Wilmington, DE for Chicago, IL on Sat, Jun 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 1044 km distance in an average of 1 d 1 h 40 m but if you time it right, some buses will get you there in just 23 h 40 m .
On Sat, Jun 20 the slowest buses will take 1 d 3 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Wilmington, DE to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $161. For those with little time consider booking a flight which can get you there in 5h 34m. The ticket price range depends on the travel mode: a bus costs an average of $161, and a train costs an average of $136.
Distance: 648 miles (1044 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$198 Average price Cheapest | $284 Average price | $210 Average price | $282 Average price (fuel + tolls) |
21h 28m Average total duration 20h 58m Onboard + 30m Additional time* | 20h 7m Average total duration 19h 37m Onboard + 30m Additional time* | 8h 34m Average total duration Fastest 5h 34m Onboard + 3h 0m Additional time* | 11h 40m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Wilmington, DE to Chicago, IL:
A bus is $12 (€10) less than a flight for this route with tickets for a flight from Wilmington, DE to Chicago, IL costing on average $210 (€172).
A bus is $86 (€70) less than a train for this route with tickets for a train from Wilmington, DE to Chicago, IL costing on average $284 (€232).
Other travel options to Chicago, IL take longer:
Train takes on average 19h 37m.
Bus takes on average 20h 58m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:25AM | Arrival Time 01:05AM | Duration 23h40 | Departure days Tue, Wed, Sun | Cheapest price $195 |
Operator Greyhound USA | Departure Time 03:30AM | Arrival Time 06:10AM | Duration 26h40 | Departure days Thu | Cheapest price $178 |
Operator Greyhound USA | Departure Time 06:00AM | Arrival Time 06:10AM | Duration 24h10 | Departure days Thu | Cheapest price $161 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 12:10PM | Duration 27h40 | Departure days Sat | Cheapest price $208 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 08:00AM | Duration 23h00 | Departure days Wed, Fri, Sun | Cheapest price $117 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 06:10AM | Duration 21h10 | Departure days Wed, Fri, Sun | Cheapest price $117 |
Operator Greyhound | Departure Time 11:20AM | Arrival Time 10:00AM | Duration 23h40 | Departure days Wed, Fri, Sun | Cheapest price $115 |
Operator Greyhound USA | Departure Time 01:50PM | Arrival Time 10:00AM | Duration 20h10 | Departure days Thu | Cheapest price $226 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 06:55PM | Duration 26h55 | Departure days Fri, Sun | Cheapest price $147 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 08:05PM | Duration 24h55 | Departure days Wed, Fri, Sun | Cheapest price $114 |
Operator Greyhound USA | Departure Time 09:25PM | Arrival Time 08:05PM | Duration 22h40 | Departure days Thu | Cheapest price $216 |
The table below shows live departures for Wilmington, DE to Chicago, IL buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 10:00 AM Wilmington, Amtrak Station @ ML King-French | 23h00 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
FlixBus+ · | 10:00 AM Wilmington, Amtrak Station @ ML King-French | 21h10 | 6:10 AM Chicago, Greyhound Bus Station | 2 transfers | |
· · · | 11:20 AM Wilmington, Amtrak Station @ ML King-French | 27h25 | 1:45 PM Chicago, Union Station (Amtrak), IL | 3 transfers | |
· | 11:20 AM Wilmington, Amtrak Station @ ML King-French | 23h40 | 10:00 AM Chicago, Greyhound Bus Station | 1 transfer | |
FlixBus+ · | 5:00 PM Wilmington, Amtrak Station @ ML King-French | 26h55 | 6:55 PM Chicago, Greyhound Bus Station | 2 transfers | |
· | 8:10 PM Wilmington, Amtrak Station @ ML King-French | 24h55 | 8:05 PM Chicago, Greyhound Bus Station | 1 transfer | |
+ FlixBus+![]() | 8:10 PM Wilmington, Amtrak Station @ ML King-French | 36h50 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| Saturday, June 20 | |||||
![]() | 1:25 AM Wilmington, DE | 23h40 | 1:05 AM Chicago, IL | 0 transfersDirect | |
![]() | 8:30 AM Wilmington, DE | 27h40 | 12:10 PM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Wilmington, DE to Chicago, IL run on average 6 times per day, taking around 20h 58m. Cheap bus tickets for this journey start at $161 (€132) but you can travel from only $136 (€111) by train.
The earliest bus runs at 03:30, the last at 23:35. The fastest bus covers the 648 miles (1044 km) distance in 21h 25m.
Distance 648 miles (1044 km) |
Average bus duration 20h 58m |
Cheapest ticket price $161 (€132) |
Buses per day 6 |
Fastest bus 21h 25m |
First bus 3:30 AM |
Last bus 11:35 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 49 days |
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Major natural history museum famous for Sue the T. rex, ancient cultures, and extensive science collections that appeal to both adults and children.
Large hands-on science museum in Hyde Park featuring a submarine, space exhibits, engineering displays, and immersive family-friendly experiences.
The city’s signature public space, home to Cloud Gate, gardens, events, and major skyline views that define modern Chicago.
Famous stretch of Michigan Avenue lined with historic buildings, shops, hotels, and frequent first-time visitor photo stops.
Highly popular waterfront promenade with architecture views, bridges, and one of the best urban walks in the city.
Chicago’s iconic thick-crust pizza baked in a deep pan, layered with cheese, toppings, and chunky tomato sauce. It is one of the city’s most famous comfort foods.
An all-beef hot dog on a poppy seed bun topped with mustard, onions, neon relish, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food.
Thinly sliced roast beef piled onto an Italian roll, often dipped in seasoned jus and topped with sweet peppers or giardiniera. It is a defining Chicago sandwich.
A historic old-school steakhouse serving steaks, chops, and classic Italian-American dishes in a traditional setting.
Chicago’s internationally acclaimed fine-dining restaurant known for highly inventive tasting menus and exceptional service.
A long-established Chicago favorite known for buttery deep-dish pizza and a casual, family-friendly atmosphere.
Moderate for a major U.S. city: casual food is manageable, but hotels, attractions, and downtown dining can be pricey.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and hotel staff a few dollars.
Find answers to the most common questions about traveling from Wilmington, DE to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Wilmington, DE to Chicago, IL buses use the Wilmington, Amtrak Station @ ML King-French to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Wilmington, DE and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need