The cheapest and fastest buses from St. Louis, MO to North Charleston, SC
Cheapest price
$186
Average price
$199
Fastest journey
1 d 4 h 45 m
Average duration
1 d 11 h 53 m
Buses per day
2
Distance
1118 km
The best way to find a cheap bus ticket from St. Louis, MO to North Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to North Charleston, SC will cost around $199 if you buy it on the day, but the cheapest tickets can be found for only $186.
It's difficult to get from St. Louis, MO to North Charleston, SC without transferring at least once.




Live departures
St. Louis, MO to North Charleston, SC bus times
The table below shows live departures for St. Louis, MO to North Charleston, SC buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:45 PM St. Louis, MO | 28h45 | 6:30 PM North Charleston, SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to North Charleston, SC by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from St. Louis, MO to North Charleston, SC
Take a bus from St. Louis, MO to North Charleston, SC and enjoy the approximately 694 miles (1118 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 08:10, the last at 15:15.
Distance 694 miles (1118 km) |
First bus 08:10 |
Last bus 15:15 |
High season Jul - Sep |
Low season Jul - Sep |
FAQs: Bus from St. Louis, MO to North Charleston, SC
Find answers to the most common questions about traveling from St. Louis, MO to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from St. Louis, MO to North Charleston, SC
Most popular bus connections from St. Louis, MO
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