St. Louis, MO to North Charleston, SC bus

Wed, Nov 04
+ Add return
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from St. Louis, MO to North Charleston, SC

Showing times, prices and bookable tickets for Nov 04
Cheapest price on Nov 04
$181
Average ticket price on Nov 04
$193
Fastest journey on Nov 04
1 d 4 h 45 m
Average journey duration on Nov 04
1 d 11 h 53 m
Buses on Nov 04
2
Distance
1118 km
Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to North Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to North Charleston, SC will cost around $193 if you buy it on the day, but the cheapest tickets can be found for only $181.

Fast buses

It's difficult to get from St. Louis, MO to North Charleston, SC without transferring at least once.

  • Flixbus USA
    1 transfer
  • Greyhound USA
    2 transfers

Journey information

Overview: Bus from St. Louis, MO to North Charleston, SC

USAUSA
USAUSA
Icon of bus

Take a bus from St. Louis, MO to North Charleston, SC and enjoy the approximately 694 miles (1118 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 08:10, the last at 15:15.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
694 miles (1118 km)
First bus
8:10 AM
Last bus
3:15 PM
Cheapest Month
May
Cheapest Day
Wed
High Season
Apr - Jun
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Frequently asked questions about your St. Louis, MO to North Charleston, SC trip

Use these quick route answers to check fares, travel time, departure options, and direct services before booking from St. Louis, MO to North Charleston, SC.

The earliest bus from St. Louis, MO to North Charleston, SC leaves at 8:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to North Charleston, SC leaves at 3:15 PM.

St. Louis, MO to North Charleston, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound USA
Departure Time
01:45PM
Arrival Time
06:30PM
Duration
28h45
Departure days
Mon, Tue, Wed, Thu, Fri, Sun
Cheapest price
$206
Operator
Flixbus USA
Departure Time
11:30PM
Arrival Time
06:30PM
Duration
43h00
Departure days
Mon, Tue, Wed, Thu, Sun
Cheapest price
$181

Live departures

St. Louis, MO to North Charleston, SC bus times

The table below shows live departures for St. Louis, MO to North Charleston, SC buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound USA1:45 PM St. Louis, MO
28h45
6:30 PM North Charleston, SC2 transfers
Flixbus USA11:30 PM St. Louis, MO
43h00
6:30 PM North Charleston, SC1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Bus providers: Greyhound, FlixBus from St. Louis, MO to North Charleston, SCYou can travel by bus between St. Louis, MO to North Charleston, SC with Greyhound, FlixBus. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
43h 0m
Cheapest FlixBus Price
$181
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
28h 45m
Cheapest Greyhound Price
$206
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Companies, tickets, and onboard amenities between St. Louis, MO and North Charleston, SC

Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.

When taking a bus from St. Louis, MO to North Charleston, SC, you can count on Greyhound, FlixBus for the best way to get you to North Charleston, SC. You can also check all possible bus companies who offer a service between St. Louis, MO and North Charleston, SC and compare the amenities they offer before buying a bus ticket.
Yes, there are bathrooms on board the bus from St. Louis, MO to North Charleston, SC for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to North Charleston, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Whether you can cancel your bus ticket from St. Louis, MO to North Charleston, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, there is food available to purchase on board the bus from St. Louis, MO to North Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to North Charleston, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to North Charleston, SC:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to North Charleston, SC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to North Charleston, SC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to North Charleston, SC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to North Charleston, SC with the following bus company: Greyhound, FlixBus.

Complete guide to North Charleston, SC

Things to do in North Charleston, SC

Discover the best of North Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect North Charleston, SC trip today.

  • Recommended

Park Circle Gallery

Contemporary visual arts center with rotating exhibitions, artist talks, and community programs inside Firefly Distillery's campus.

  • Recommended

Children's Museum of the Lowcountry

Hands-on children's museum with imaginative exhibits and play spaces that encourage learning through movement and creativity.

North Charleston Fire Museum

Museum in the old North Charleston fire station featuring local firefighting history, restored apparatus, and memorabilia.

United States Dollar ($)

Moderate for U.S. city travel. Hotels and dining are lower than major hubs, but car use and limited transit can raise total visitor costs.

Average meal costs

Budget
$10-15 for fast food or casual takeout.
Mid-range
$20-35 per person for a restaurant meal.
Fine dining
$50+ per person for upscale dining.
Coffee
$3-6 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Cafes often have tip jars or screen prompts; $1-2 is common.

Plan your visit to North Charleston, SC

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in North Charleston, SC.

The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In North Charleston, SC, travelers should be cautious of petty crimes such as pickpocketing and car break-ins, especially in crowded or poorly lit areas. It is advisable to avoid displaying valuables and remain aware of surroundings. Common scams include overcharging by unlicensed taxi or ride-share drivers and fraudulent ticket sales for local attractions. Staying in well-populated areas and using reputable transportation services can help mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Bus from St. Louis, MO to North Charleston, SC

Find answers to the most common questions about traveling from St. Louis, MO to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and North Charleston, SC including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

popular bus stations

Popular bus stations from St. Louis, MO to North Charleston, SC

Most St. Louis, MO to North Charleston, SC buses use the St. Louis, S 15th St (Civic center) to station pair. Use this guide to compare St. Louis, MO and North Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in North Charleston

Which St. Louis, MO station do buses to North Charleston, SC leave from?

Buses from St. Louis, MO to North Charleston, SC leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $2 · every ~9 min

St. Louis, S 15th St (Civic center) bus station facilities and services

St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).

Tickets and information

Ticket office support is available at St. Louis, S 15th St (Civic center).

Parking, taxis and toilets

Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.

More options for your journey from St. Louis, MO to North Charleston, SC

Here are some other resources that might have the information you need

Most popular buses to and from North Charleston, SC and St. Louis, MO

HomeBusesBuses in USASt. Louis, MO to North Charleston, SC bus

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