St. Louis, MO to North Charleston, SC bus with Greyhound

Sun, Jun 21
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from St. Louis, MO to North Charleston, SC

Showing times and prices for Jun 21

Cheapest price

$184

Average price

$197

Fastest journey

1 d 4 h 45 m

Average duration

1 d 11 h 53 m

Buses per day

2

Distance

1118 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to North Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to North Charleston, SC will cost around $197 if you buy it on the day, but the cheapest tickets can be found for only $184.

Fast buses

It's difficult to get from St. Louis, MO to North Charleston, SC without transferring at least once.

  • Flixbus USA
    11:30 PM43h00
    St. Louis, MO
    6:30 PMNorth Charleston, SC
    $1841One-way
    1 transfer
  • Greyhound USA
    1:45 PM28h45
    St. Louis, MO
    6:30 PMNorth Charleston, SC
    $2101One-way
    2 transfers

Travel Information

Compare train and bus for St. Louis, MO to North Charleston, SC

Omio recommends booking the train as it is the most popular option from St. Louis, MO to North Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $184. For those with little time consider booking a bus which can get you there in 35h 14m. The ticket price range depends on the travel mode: a bus costs an average of $184, and a train costs an average of $712.

Distance: 694 miles (1118 km)

Compare bus with

Bus
Most popular
Train
Driving

$198

Average price

Cheapest

$712

Average price

$169

Average price

(fuel + tolls)

35h 44m

Average total duration

Fastest

35h 14m

Onboard

+

30m

Additional time*

45h 8m

Average total duration

44h 38m

Onboard

+

30m

Additional time*

12h 42m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from St. Louis, MO to North Charleston, SC is a bus with an average price of $198 (€162).

This is compared to other travel options from St. Louis, MO to North Charleston, SC:

A bus is $514 (€421) less than a train for this route with tickets for a train from St. Louis, MO to North Charleston, SC costing on average $712 (€583).

The fastest way to travel from St. Louis, MO to North Charleston, SC is by bus with an average journey time of 35h 14m.

Other travel options to North Charleston, SC take longer:

Train takes on average 44h 38m.

It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and North Charleston, SC including taking a train and bus.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to North Charleston, SC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

St. Louis, MO to North Charleston, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound USA
Departure Time
01:45PM
Arrival Time
06:30PM
Duration
28h45
Departure days
Mon, Tue, Wed, Thu, Fri, Sun
Cheapest price
$210
Operator
Flixbus USA
Departure Time
11:30PM
Arrival Time
06:30PM
Duration
43h00
Departure days
Mon, Tue, Wed, Thu, Sun
Cheapest price
$184

Live departures

St. Louis, MO to North Charleston, SC bus times

The table below shows live departures for St. Louis, MO to North Charleston, SC buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound USA1:45 PM St. Louis, MO
28h45
6:30 PM North Charleston, SC2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to North Charleston, SC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27

Why should you book St. Louis, MO to North Charleston, SC buses with Omio?

Greyhound as well as FlixBus offer buses services from St. Louis, MO to North Charleston, SC.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to North Charleston, SC.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to North Charleston, SC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from St. Louis, MO to North Charleston, SC.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to North Charleston, SC.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from St. Louis, MO to North Charleston, SC.

Journey information

Overview: Bus from St. Louis, MO to North Charleston, SC

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to North Charleston, SC run on average 1 times per day, taking around 35h 14m. Cheap bus tickets for this journey start at $184 (€151) if you book in advance.

The earliest bus runs at 08:10, the last at 15:15. The fastest bus covers the 694 miles (1118 km) distance in 28h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
694 miles (1118 km)
Average bus duration
35h 14m
Cheapest ticket price
$184 (€151)
Buses per day
1
Fastest bus
28h 45m
First bus
8:10 AM
Last bus
3:15 PM
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from St. Louis, MO to North Charleston, SCYou can travel by bus between St. Louis, MO to North Charleston, SC with Greyhound, FlixBus for as low as $184 (€151). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
43h 0m
Cheapest Price
$184 (€151)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
28h 45m
Cheapest Price
$210 (€172)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from St. Louis, MO to North Charleston, SC

Find answers to the most common questions about traveling from St. Louis, MO to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to North Charleston, SC can start from as little as $184 (€151) when you book in advance. The average bus ticket price for St. Louis, MO to North Charleston, SC is $198 (€162) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to North Charleston, SC is 28h 45m to travel the 694 miles (1118 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to North Charleston, SC leaves at 8:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to North Charleston, SC leaves at 3:15 PM.
There are 1 buses a day from St. Louis, MO to North Charleston, SC which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to North Charleston, SC, you can count on Greyhound, FlixBus for the best way to get you to North Charleston, SC. You can also check all possible bus companies who offer a service between St. Louis, MO and North Charleston, SC and compare the amenities they offer before buying a bus ticket.
A trip to North Charleston, SC from St. Louis, MO is worth doing but not as a day trip with a journey time of 28h 45m each way. Check with Omio app the best way to travel.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and North Charleston, SC including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to North Charleston, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to North Charleston, SC for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from St. Louis, MO to North Charleston, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to North Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to North Charleston, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to North Charleston, SC:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to North Charleston, SC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to North Charleston, SC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to North Charleston, SC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to North Charleston, SC with the following bus company: Greyhound, FlixBus.
Since neither St. Louis, MO nor North Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to North Charleston, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In North Charleston, SC, travelers should be cautious of petty crimes such as pickpocketing and car break-ins, especially in crowded or poorly lit areas. It is advisable to avoid displaying valuables and remain aware of surroundings. Common scams include overcharging by unlicensed taxi or ride-share drivers and fraudulent ticket sales for local attractions. Staying in well-populated areas and using reputable transportation services can help mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from St. Louis, MO to North Charleston, SC

Most St. Louis, MO to North Charleston, SC buses use the St. Louis, S 15th St (Civic center) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare St. Louis, MO and North Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in North Charleston
St. Louis, S 15th St (Civic center)
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min

More options for your journey from St. Louis, MO to North Charleston, SC

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