- Recommended
Park Circle Gallery
Contemporary visual arts center with rotating exhibitions, artist talks, and community programs inside Firefly Distillery's campus.
The best way to find a cheap bus ticket from Pittsburgh, PA to North Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to North Charleston, SC will cost around $166 if you buy it on the day, but the cheapest tickets can be found for only $166.
It's difficult to get from Pittsburgh, PA to North Charleston, SC without transferring at least 2 times.

|
| ||||||||||||

|
| ||||||||||||
Buses from Pittsburgh, PA to North Charleston, SC run on average 4 times per day, taking around 22h 11m. Cheap bus tickets for this journey start at $188 if you book in advance.
The earliest bus runs at 08:30, the last at 21:00. The fastest bus covers the 521 miles (840 km) distance in 18h 9m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pittsburgh, PA to North Charleston, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 11:30PM | Duration 22h00 | Departure days Sun | Cheapest price $240 |
Operator Greyhound USA | Departure Time 08:30AM | Arrival Time 06:30PM | Duration 34h00 | Departure days Wed, Thu | Cheapest price $166 |
Operator Flixbus USA | Departure Time 11:45AM | Arrival Time 06:30PM | Duration 30h45 | Departure days Fri, Sun | Cheapest price $147 |
The table below shows live departures for Pittsburgh, PA to North Charleston, SC buses for tomorrow, Wednesday, November 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:30 AM Pittsburgh, PA | 34h00 | 6:30 PM North Charleston, SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Pittsburgh, PA to North Charleston, SC with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of North Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect North Charleston, SC trip today.
Contemporary visual arts center with rotating exhibitions, artist talks, and community programs inside Firefly Distillery's campus.
Hands-on children's museum with imaginative exhibits and play spaces that encourage learning through movement and creativity.
Museum in the old North Charleston fire station featuring local firefighting history, restored apparatus, and memorabilia.
Popular neighborhood with a traffic circle, indie shops, murals, and a relaxed local feel ideal for strolling and events.
Large regional park with paved trails, sports facilities, wetlands, and broad open space for walking and outdoor recreation.
Scenic riverfront green space at the former Navy Yard with lawns, public art, and views toward the Cooper River and bridge.
Lowcountry shrimp and grits pairs local shrimp with creamy grits, often with gravy or bacon. It is a signature coastal South Carolina comfort dish.
She-crab soup is a rich Charleston classic made with crab meat, crab roe, cream, and sherry. It is a traditional Lowcountry seafood specialty.
Hoppin' John combines rice, field peas, pork, and seasonings. It is a longstanding Carolina dish tied to Lowcountry and New Year traditions.
Casual barbecue spot known for smoked meats and hearty Southern sides in a lively, no-frills setting.
Popular brewery and restaurant serving house beers, wood-fired pizza, and pub fare in an energetic industrial space.
Polished oyster bar and seafood restaurant specializing in fresh shellfish and Lowcountry flavors in a stylish setting.
Moderate for U.S. city travel. Hotels and dining are lower than major hubs, but car use and limited transit can raise total visitor costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Cafes often have tip jars or screen prompts; $1-2 is common.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in North Charleston, SC.
Find answers to the most common questions about traveling from Pittsburgh, PA to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

Most Pittsburgh, PA to North Charleston, SC buses use the Pittsburgh, Greyhound Bus Station to station pair. Use this guide to compare Pittsburgh, PA and North Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available on site
Available throughout the station. ATMs are aTM located near the entrance.
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.