- Recommended
Park Circle Gallery
Contemporary visual arts center with rotating exhibitions, artist talks, and community programs inside Firefly Distillery's campus.
The best way to find a cheap bus ticket from Orlando, FL to North Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to North Charleston, SC will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $146.
On Wed, Nov 04, we found 1 buses from Orlando, FL to North Charleston, SC, including 1 direct services.
On Wed, Nov 04 the direct buses cover the 501 km distance in an average of 14 h 30 m but if you time it right, some buses will get you there in just 14 h 30 m .
On Wed, Nov 04 the slowest buses will take 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Take a bus from Orlando, FL to North Charleston, SC and enjoy the approximately 311 miles (501 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 04:00, the last at 23:40.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Orlando, FL to North Charleston, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:00AM | Arrival Time 02:55PM | Duration 8h55 | Departure days Fri | Cheapest price $68 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 10:30PM | Duration 14h30 | Departure days Tue, Wed | Cheapest price $82 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:30PM | Duration 13h45 | Departure days Sun | Cheapest price $143 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 11:30PM | Duration 13h45 | Departure days Mon, Thu, Sat | Cheapest price $146 |
The table below shows live departures for Orlando, FL to North Charleston, SC buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 AM Orlando, FL | 14h30 | 10:30 PM North Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of North Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect North Charleston, SC trip today.
Contemporary visual arts center with rotating exhibitions, artist talks, and community programs inside Firefly Distillery's campus.
Hands-on children's museum with imaginative exhibits and play spaces that encourage learning through movement and creativity.
Museum in the old North Charleston fire station featuring local firefighting history, restored apparatus, and memorabilia.
Popular neighborhood with a traffic circle, indie shops, murals, and a relaxed local feel ideal for strolling and events.
Large regional park with paved trails, sports facilities, wetlands, and broad open space for walking and outdoor recreation.
Scenic riverfront green space at the former Navy Yard with lawns, public art, and views toward the Cooper River and bridge.
Lowcountry shrimp and grits pairs local shrimp with creamy grits, often with gravy or bacon. It is a signature coastal South Carolina comfort dish.
She-crab soup is a rich Charleston classic made with crab meat, crab roe, cream, and sherry. It is a traditional Lowcountry seafood specialty.
Hoppin' John combines rice, field peas, pork, and seasonings. It is a longstanding Carolina dish tied to Lowcountry and New Year traditions.
Casual barbecue spot known for smoked meats and hearty Southern sides in a lively, no-frills setting.
Popular brewery and restaurant serving house beers, wood-fired pizza, and pub fare in an energetic industrial space.
Polished oyster bar and seafood restaurant specializing in fresh shellfish and Lowcountry flavors in a stylish setting.
Moderate for U.S. city travel. Hotels and dining are lower than major hubs, but car use and limited transit can raise total visitor costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Cafes often have tip jars or screen prompts; $1-2 is common.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in North Charleston, SC.
Find answers to the most common questions about traveling from Orlando, FL to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

Most Orlando, FL to North Charleston, SC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to station pair. Use this guide to compare Orlando, FL and North Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.