Harrisburg, PA to North Charleston, SC bus

Sun, Mar 22
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FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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Travel Information

Compare train, bus, and flight for Harrisburg, PA to North Charleston, SC

Omio recommends booking the train as it is the most popular option from Harrisburg, PA to North Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $205. For those with little time consider booking a flight which can get you there in 6h 2m. The ticket price range depends on the travel mode: a bus costs an average of $205, and a flight costs an average of $421.

Distance: 538 miles (867 km)

Compare bus with

Bus
Most popular
Train
Flight

$205

Average price

Cheapest

$214

Average price

$421

Average price

28h 10m

Average total duration

27h 40m

Onboard

+

30m

Additional time*

14h 5m

Average total duration

13h 35m

Onboard

+

30m

Additional time*

9h 2m

Average total duration

Fastest

6h 2m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Harrisburg, PA to North Charleston, SC by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Harrisburg, PA to North Charleston, SC

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Buses from Harrisburg, PA to North Charleston, SC run on average 3 times per day, taking around 27h 40m. Cheap bus tickets for this journey start at $205 (€166) if you book in advance.

The earliest bus runs at 11:15, the last at 14:50. The fastest bus covers the 538 miles (867 km) distance in 27h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
538 miles (867 km)
Average bus duration
27h 40m
Cheapest ticket price
$205 (€166)
Buses per day
3
Fastest bus
27h 40m
First bus
11:15
Last bus
14:50
Cheapest month
Aug
Cheapest day
Mon
High season
Jul - Sep
Low season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Harrisburg, PA to North Charleston, SC

Find answers to the most common questions about traveling from Harrisburg, PA to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Harrisburg, PA to North Charleston, SC can start from as little as $205 (€166) when you book in advance. The average bus ticket price for Harrisburg, PA to North Charleston, SC is $205 (€166) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to North Charleston, SC is 27h 40m to travel the 538 miles (867 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to North Charleston, SC leaves at 11:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to North Charleston, SC leaves at 2:50 PM.
A trip to North Charleston, SC from Harrisburg, PA is worth doing but not as a day trip with a journey time of 27h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to North Charleston, SC is August.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and North Charleston, SC including taking a train, bus, and flight.
No, the bus from Harrisburg, PA to North Charleston, SC has no accessibility options.
No, there are no bathrooms on board the bus from Harrisburg, PA to North Charleston, SC.
No, bikes are not allowed on board the bus from Harrisburg, PA to North Charleston, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Harrisburg, PA to North Charleston, SC.
No, luggage for the bus from Harrisburg, PA to North Charleston, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Harrisburg, PA to North Charleston, SC.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to North Charleston, SC.
No, there are no USB plugs on board the bus from Harrisburg, PA to North Charleston, SC.
No, there is no WiFi on board the bus from Harrisburg, PA to North Charleston, SC.

popular bus stations

Popular bus stations from Harrisburg, PA to North Charleston, SC

Harrisburg
North Charleston
Harrisburg, Market St (Bus Station)
information
Harrisburg, Chestnut Street / South 4th Street
information

More options for your journey from Harrisburg, PA to North Charleston, SC

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Most popular buses to and from North Charleston, SC and Harrisburg, PA

Most popular bus connections to North Charleston, SC

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