Travel Information
Compare train, flight, and bus for Harrisburg, PA to North Charleston, SC
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to North Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €94. For those with little time consider booking a train which can get you there in 13h 35m. The ticket price range depends on the travel mode: a bus costs an average of €94, and a flight costs an average of €843.
Distance: 538 miles (867 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€94 Average price Cheapest | €203 Average price | €843 Average price |
24h 30m Average total duration 24h 0m Onboard + 30m Additional time* | 14h 5m Average total duration Fastest 13h 35m Onboard + 30m Additional time* | 18h 37m Average total duration 15h 37m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Harrisburg, PA to North Charleston, SC by train, flight, or bus
Compare train, flight, and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Harrisburg, PA to North Charleston, SC
Buses from Harrisburg, PA to North Charleston, SC run on average 3 times per day, taking around 24h 0m. Cheap bus tickets for this journey start at $118 (€94) if you book in advance.
The earliest bus runs at 10:20, the last at 15:15. The fastest bus covers the 538 miles (867 km) distance in 24h 0m.
Distance 538 miles (867 km) |
Average bus duration 24h 0m |
Cheapest ticket price $118 (€94) |
Buses per day 3 |
Fastest bus 24h 0m |
First bus 10:20 |
Last bus 15:15 |
FAQs: Bus from Harrisburg, PA to North Charleston, SC
Find answers to the most common questions about traveling from Harrisburg, PA to North Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at North Charleston, SC, this guide helps you travel smarter and with confidence.

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Popular bus stations from Harrisburg, PA to North Charleston, SC
Most popular bus connections from Harrisburg, PA
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