The cheapest and fastest buses from St. Louis, MO to Detroit, MI
Cheapest price
$143
Average price
$143
Fastest journey
19 h 15 m
Average duration
19 h 15 m
Buses per day
1
Distance
731 km
The best way to find a cheap bus ticket from St. Louis, MO to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Detroit, MI will cost around $143 if you buy it on the day, but the cheapest tickets can be found for only $143.
Of the 1 buses that leave St. Louis, MO for Detroit, MI on Thu, Nov 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 731 km distance in an average of 19 h 15 m but if you time it right, some buses will get you there in just 19 h 15 m .
On Thu, Nov 06 the slowest buses will take 19 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for St. Louis, MO to Detroit, MI
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from €53. For those with little time consider booking a flight which can get you there in 5h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of €53, and a flight costs an average of €26.
Distance: 454 miles (731 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€86 Average price Cheapest | €122 Average price | €225 Average price |
14h 24m Average total duration 13h 54m Onboard + 30m Additional time* | 11h 1m Average total duration 10h 31m Onboard + 30m Additional time* | 8h 22m Average total duration Fastest 5h 22m Onboard + 3h 0m Additional time* |
0.7 - 1.8kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.2 - 4.4kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
St. Louis, MO to Detroit, MI Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:45AM | Arrival Time 10:55PM | Duration 13h10 | Departure days Fri | Cheapest price $96 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 06:00AM | Duration 19h30 | Departure days Fri | Cheapest price $117 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 09:55AM | Duration 19h00 | Departure days Fri | Cheapest price $96 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 02:45PM | Duration 14h15 | Departure days Fri | Cheapest price $93 |
Live departures
St. Louis, MO to Detroit, MI bus times
The table below shows live departures for St. Louis, MO to Detroit, MI buses for today, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:45 PM St. Louis, MO | 19h15 | 10:00 AM Detroit, MI | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Detroit, MI by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Journey information
Overview: Bus from St. Louis, MO to Detroit, MI
Distance 454 miles (731 km) |
Average bus duration 13h 54m |
Cheapest ticket price $65 (€53) |
Buses per day 6 |
Fastest bus 13h 10m |
First bus 02:00 |
Last bus 23:55 |
Bus providers: Greyhound from St. Louis, MO to Detroit, MIYou can travel by bus between St. Louis, MO to Detroit, MI with Greyhound for as low as $32 (€26). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Detroit, MI

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Detroit Institute of Arts, a renowned museum housing over 65,000 artworks from various cultures and eras
- The Henry Ford, a sprawling complex dedicated to American innovation and history, featuring the Henry Ford Museum and Greenfield Village
- Detroit Riverwalk, a scenic promenade along the Detroit River offering views, parks, and recreational activities
- Belle Isle Park, a 982-acre island park with attractions like an aquarium, conservatory, and nature trails
- Guardian Building, an iconic skyscraper known for its stunning Art Deco architecture and vibrant interior design.
- Motown Museum, the iconic birthplace of the Motown Sound offering guided tours of the historic recording studios
- Eastern Market, a vibrant public market offering fresh produce, local goods, and a lively atmosphere with events and street art
- Detroit Historical Museum, showcasing the rich history of Detroit through engaging exhibits and interactive displays
- Detroit Zoo, featuring a wide variety of animals and immersive habitats
- Comerica Park, a baseball stadium offering games, tours, and family-friendly activities.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from St. Louis, MO to Detroit, MI, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Detroit, MI
Most popular bus connections from St. Louis, MO
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