- Must visit
Detroit Institute of Arts
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Cheapest price on Sep 19
€61
Average ticket price on Sep 19
€79
Fastest journey on Sep 19
13 h 10 m
Average journey duration on Sep 19
13 h 36 m
Buses on Sep 19
8
Distance
731 km
The best way to find a cheap bus ticket from St. Louis, MO to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Detroit, MI will cost around €79 if you buy it on the day, but the cheapest tickets can be found for only €61.
It's difficult to get from St. Louis, MO to Detroit, MI without transferring at least once.
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· Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Detroit, MI among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €81 For those with little time, consider booking a flight, which has an average total journey time of 6h 26m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of €81, while a flight costs an average of €489.
Distance: 454 miles (731 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€81 Average price Cheapest | €489 Average price | €152 Average price | €87 Average price (fuel + tolls) |
12h 59m Average total duration 12h 29m Onboard + 30m Additional time* | 6h 26m Average total duration Fastest 4h 26m Onboard + 2h 0m Additional time* | 11h 11m Average total duration 10h 41m Onboard + 30m Additional time* | 7h 46m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.4kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to Detroit, MI:
A bus is €70 less than a train for this route with tickets for a train from St. Louis, MO to Detroit, MI costing on average €152.
A bus is €408 less than a flight for this route with tickets for a flight from St. Louis, MO to Detroit, MI costing on average €489.
Other travel options to Detroit, MI take longer:
Train takes on average 10h 41m.
Bus takes on average 12h 29m.
Tickets start at around €81 compared to roughly €87 in fuel and tolls — a saving of about €6. The journey takes 12h 29m versus 7h 46m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 05:00PM | Duration 14h00 | Departure days Everyday | Cheapest price €48 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 10:55PM | Duration 13h10 | Departure days Everyday | Cheapest price €49 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 06:50AM | Duration 15h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €56 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 06:50AM | Duration 13h50 | Departure days Tue, Wed, Sat | Cheapest price €49 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 03:40PM | Duration 15h10 | Departure days Mon | Cheapest price €57 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 02:45PM | Duration 14h15 | Departure days Thu, Fri, Sat, Sun | Cheapest price €56 |
The table below shows live departures for St. Louis, MO to Detroit, MI buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 8:45 AM St. Louis, S 15th St (Civic center) | 13h10 | 10:55 PM Detroit, Greyhound Terminal | 1 transfer | |
FlixBus+![]() | 2:30 PM St. Louis, S 15th St (Civic center) | 15h20 | 6:50 AM Detroit, Greyhound Terminal | 1 transfer | |
FlixBus+![]() | 11:30 PM St. Louis, S 15th St (Civic center) | 14h15 | 2:45 PM Detroit, Greyhound Terminal | 1 transfer | |
| Saturday, September 19 | |||||
· | 2:00 AM St. Louis, S 15th St (Civic center) | 14h00 | 5:00 PM Detroit, Greyhound Terminal | 1 transfer | |
· | 2:00 AM St. Louis, S 15th St (Civic center) | 13h50 | 4:50 PM Detroit, Greyhound Terminal | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Detroit, MI run on average 4 times per day, taking around 12h 29m. Cheap bus tickets for this journey start at €48 if you book in advance.
The earliest bus runs at 02:00, the last at 23:55. The fastest bus covers the 454 miles (731 km) distance in 9h 50m.
Distance 454 miles (731 km) |
Average bus duration 12h 29m |
Cheapest ticket price €48 |
Buses per day 4 |
Fastest bus 9h 50m |
First bus 2:00 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 28 days |
Discover the best of Detroit, MI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit, MI trip today.
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Immersive museum of African American history, culture, and achievement with strong regional and national storytelling.
Motown’s original Studio A preserves the sound and stories behind legendary recordings that shaped popular music worldwide.
Riverfront promenade with public art, plazas, and skyline views; one of the city’s best places for a scenic walk.
Large island park with gardens, trails, beaches, and major attractions, offering a nature escape minutes from downtown.
Revived public square at the city center, hosting events, seasonal programming, and easy access to downtown landmarks.
A square deep-dish pizza with a crisp, caramelized cheese edge and striped sauce. It is Detroit’s signature pie, born in blue steel auto pans.
A hot dog topped with chili, mustard, and diced onions on a steamed bun. It is a classic Detroit street food tied to Greek-American diners.
A layered sandwich of corned beef, swiss cheese, coleslaw, and Russian dressing on grilled rye. It is a beloved deli staple in metro Detroit.
Acclaimed fine-dining restaurant focused on seasonal tasting menus and polished service. One of Detroit’s top special-occasion destinations.
Beloved Eastern Market bakery known for paczki, cakes, and old-school sweets. Expect a busy, nostalgic counter-service experience.
Historic downtown institution famous for Detroit-style square pizza in a lively, casual setting with old-school local character.
Moderate for US city breaks: hotels and dining are mid-priced, transit is limited, and car or rideshare costs can raise daily spend.
Tip 18-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or about 10% in cafes if there is table service.
Find answers to the most common questions about traveling from St. Louis, MO to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Detroit, MI buses use the St. Louis, S 15th St (Civic center) to Detroit, Greyhound Terminal station pair. Use this guide to compare St. Louis, MO and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
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