- Must visit
Detroit Institute of Arts
An expansive art museum housing a diverse collection from ancient to modern art, noted for Diego Rivera's Detroit Industry murals.
Flights from St. Louis, MO to Detroit, MI depart on average 41 times per day, taking around 4h 52m. Cheap flight tickets for this journey start at $110 (€89) but you can travel from only $64 (€52) by bus.
The earliest flight runs at 05:00, the last at 22:30. The fastest flight covers the 454 miles (731 km) distance in 3h 32m. August is the cheapest month to fly.
Distance 454 miles (731 km) |
Average flight duration 4h 52m |
Cheapest ticket price $110 (€89) |
Flights per day 41 |
Fastest flight 3h 32m |
First flight 5:00 AM |
Last flight 10:30 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Tue |
Best time to book 7 days |
Cheapest price
$161
Average price
$458
Fastest journey
3 h 59 m
Average duration
4 h 53 m
Flights per day
8
Distance
731 km
The best way to find a cheap flight ticket from St. Louis, MO to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Detroit, MI will cost around $458 if you buy it on the day, but the cheapest tickets can be found for only $161.
Of the 8 flights that leave St. Louis, MO for Detroit, MI onTue, May 19, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 19 the direct flights cover the 731 km distance in an average of 4 h 53 m but if you time it right, some flights will get you there in just 3 h 59 m .
On Tue, May 19 the longest flights will take 5 h 47 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the train as it is the most popular option from St. Louis, MO to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a flight which can get you there in 4h 52m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $64, and a flight costs an average of $110.
Distance: 454 miles (731 km)
| Flight | Most popular Train | Bus | Driving |
|---|---|---|---|
$387 Average price | $164 Average price | $127 Average price Cheapest | $106 Average price (fuel + tolls) |
7h 52m Average total duration Fastest 4h 52m Onboard + 3h 0m Additional time* | 10h 58m Average total duration 10h 28m Onboard + 30m Additional time* | 13h 37m Average total duration 13h 7m Onboard + 30m Additional time* | 7h 46m Average total duration (door-to-door) |
2.2 - 4.4kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to Detroit, MI:
A bus is $37 (€30) less than a train for this route with tickets for a train from St. Louis, MO to Detroit, MI costing on average $164 (€133).
A bus is $260 (€210) less than a flight for this route with tickets for a flight from St. Louis, MO to Detroit, MI costing on average $387 (€313).
Other travel options to Detroit, MI take longer:
Train takes on average 10h 28m.
Bus takes on average 13h 7m.
The table below shows live departures for St. Louis, MO to Detroit, MI flights for today, Sunday, May 17. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
UA1371 · UA4064 | 6:00 AM St. Louis Lambert International Airport | 6h24 | 1:24 PM Detroit Wayne County Airport | 1 transfer | |
UA1371 · UA685 | 6:00 AM St. Louis Lambert International Airport | 16h47 | 11:47 PM Detroit Wayne County Airport | 1 transfer | |
UA1371 · UA6119 | 6:00 AM St. Louis Lambert International Airport | 9h06 | 4:06 PM Detroit Wayne County Airport | 1 transfer | |
UA3621 · UA3622 | 6:15 AM St. Louis Lambert International Airport | 8h33 | 3:48 PM Detroit Wayne County Airport | 1 transfer | |
UA3621 · UA3586 | 6:15 AM St. Louis Lambert International Airport | 13h28 | 8:43 PM Detroit Wayne County Airport | 1 transfer | |
UA3621 · UA3437 | 6:15 AM St. Louis Lambert International Airport | 11h08 | 6:23 PM Detroit Wayne County Airport | 1 transfer | |
UA4423 · UA5756 | 6:30 AM St. Louis Lambert International Airport | 5h30 | 1:00 PM Detroit Wayne County Airport | 1 transfer | |
AA858 · AA2054 | 7:00 AM St. Louis Lambert International Airport | 6h50 | 2:50 PM Detroit Wayne County Airport | 1 transfer | |
AA2444+ AA3563 | 7:05 AM St. Louis Lambert International Airport | 8h57 | 5:02 PM Detroit Wayne County Airport | 1 transfer | |
AA2444+ AA4058 | 7:05 AM St. Louis Lambert International Airport | 4h52 | 12:57 PM Detroit Wayne County Airport | 1 transfer | |
AA1410 · AA2037 | 7:12 AM St. Louis Lambert International Airport | 6h36 | 2:48 PM Detroit Wayne County Airport | 1 transfer | |
UA473 · UA5756 | 7:45 AM St. Louis Lambert International Airport | 4h15 | 1:00 PM Detroit Wayne County Airport | 1 transfer | |
UA4569 · UA5756 | 8:21 AM St. Louis Lambert International Airport | 3h39 | 1:00 PM Detroit Wayne County Airport | 1 transfer | |
AA5454+ AA4618 | 8:36 AM St. Louis Lambert International Airport | 4h44 | 2:20 PM Detroit Wayne County Airport | 1 transfer | |
UA4506 · UA2265 | 8:45 AM St. Louis Lambert International Airport | 13h59 | 11:44 PM Detroit Wayne County Airport | 1 transfer | |
UA4506 · UA3643 | 8:45 AM St. Louis Lambert International Airport | 9h16 | 7:01 PM Detroit Wayne County Airport | 1 transfer | |
UA1302 · UA1220 | 8:46 AM St. Louis Lambert International Airport | 13h07 | 10:53 PM Detroit Wayne County Airport | 1 transfer | |
AA3563 · AA4135 | 8:57 AM St. Louis Lambert International Airport | 7h05 | 5:02 PM Detroit Wayne County Airport | 1 transfer | |
AA2950 · AA2054 | 9:10 AM St. Louis Lambert International Airport | 4h40 | 2:50 PM Detroit Wayne County Airport | 1 transfer | |
AA2942 · AA2045 | 9:34 AM St. Louis Lambert International Airport | 7h52 | 6:26 PM Detroit Wayne County Airport | 1 transfer | |
UA4494 · UA6049 | 11:15 AM St. Louis Lambert International Airport | 5h04 | 5:19 PM Detroit Wayne County Airport | 1 transfer | |
UA3573 · UA3586 | 11:34 AM St. Louis Lambert International Airport | 8h09 | 8:43 PM Detroit Wayne County Airport | 1 transfer | |
UA4454 · UA2265 | 12:15 PM St. Louis Lambert International Airport | 10h29 | 11:44 PM Detroit Wayne County Airport | 1 transfer | |
AA1926+ AA6245 | 12:27 PM St. Louis Lambert International Airport | 7h54 | 9:21 PM Detroit Wayne County Airport | 1 transfer | |
AA2941 · AA2508 | 12:27 PM St. Louis Lambert International Airport | 8h16 | 9:43 PM Detroit Wayne County Airport | 1 transfer | |
AA1926+ AA3563 | 12:27 PM St. Louis Lambert International Airport | 3h35 | 5:02 PM Detroit Wayne County Airport | 1 transfer | |
UA4592 · UA3465 | 1:24 PM St. Louis Lambert International Airport | 4h36 | 7:00 PM Detroit Wayne County Airport | 1 transfer | |
AA2958 · AA2055 | 2:12 PM St. Louis Lambert International Airport | 7h16 | 10:28 PM Detroit Wayne County Airport | 1 transfer | |
AA3110+ AA6447 | 2:33 PM St. Louis Lambert International Airport | 9h12 | 12:45 AM Detroit Wayne County Airport | 1 transfer | |
AA6447+ AA3382 | 2:33 PM St. Louis Lambert International Airport | 7h59 | 11:32 PM Detroit Wayne County Airport | 1 transfer | |
AA6447 · AA6245 | 2:33 PM St. Louis Lambert International Airport | 5h48 | 9:21 PM Detroit Wayne County Airport | 1 transfer | |
UA1729 · UA1220 | 2:35 PM St. Louis Lambert International Airport | 7h18 | 10:53 PM Detroit Wayne County Airport | 1 transfer | |
UA4487 · UA5232 | 3:20 PM St. Louis Lambert International Airport | 3h56 | 8:16 PM Detroit Wayne County Airport | 1 transfer | |
AA690+ AA3917 | 3:38 PM St. Louis Lambert International Airport | 6h21 | 10:59 PM Detroit Wayne County Airport | 1 transfer | |
AA5446 · AA5541 | 3:43 PM St. Louis Lambert International Airport | 5h33 | 10:16 PM Detroit Wayne County Airport | 1 transfer | |
AA6399 · AA6245 | 4:30 PM St. Louis Lambert International Airport | 3h51 | 9:21 PM Detroit Wayne County Airport | 1 transfer | |
AA3382+ AA6399 | 4:30 PM St. Louis Lambert International Airport | 6h02 | 11:32 PM Detroit Wayne County Airport | 1 transfer | |
AA3110+ AA6399 | 4:30 PM St. Louis Lambert International Airport | 7h15 | 12:45 AM Detroit Wayne County Airport | 1 transfer | |
UA6219 · UA685 | 4:44 PM St. Louis Lambert International Airport | 6h03 | 11:47 PM Detroit Wayne County Airport | 1 transfer | |
AA418 · AA3110 | 5:21 PM St. Louis Lambert International Airport | 6h24 | 12:45 AM Detroit Wayne County Airport | 1 transfer | |
AA418+ AA3382 | 5:21 PM St. Louis Lambert International Airport | 5h11 | 11:32 PM Detroit Wayne County Airport | 1 transfer | |
UA3502 · UA3622 | 5:25 PM St. Louis Lambert International Airport | 21h23 | 3:48 PM Detroit Wayne County Airport | 1 transfer | |
UA3502 · UA3437 | 5:25 PM St. Louis Lambert International Airport | 23h59 | 6:24 PM Detroit Wayne County Airport | 1 transfer | |
UA3502 · UA3700 | 5:25 PM St. Louis Lambert International Airport | 16h29 | 10:54 AM Detroit Wayne County Airport | 1 transfer | |
UA5764 · UA3476 | 5:28 PM St. Louis Lambert International Airport | 5h31 | 11:59 PM Detroit Wayne County Airport | 1 transfer | |
UA5764 · UA1050 | 5:28 PM St. Louis Lambert International Airport | 3h45 | 10:13 PM Detroit Wayne County Airport | 1 transfer | |
UA1770 · UA1877 | 5:59 PM St. Louis Lambert International Airport | 19h32 | 2:31 PM Detroit Wayne County Airport | 1 transfer | |
AA2943 · AA370 | 6:54 PM St. Louis Lambert International Airport | 4h31 | 12:25 AM Detroit Wayne County Airport | 1 transfer | |
UA4580 · UA3476 | 7:09 PM St. Louis Lambert International Airport | 3h50 | 11:59 PM Detroit Wayne County Airport | 1 transfer | |
| Monday, May 18 | |||||
![]() | 1:15 AM St. Louis, MO | 4h01 | 5:16 AM Detroit, MI | 0 transfersDirect | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Detroit — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit trip today.
An expansive art museum housing a diverse collection from ancient to modern art, noted for Diego Rivera's Detroit Industry murals.
While located in Dearborn, near Detroit, this historical museum features exhibits on innovation, including the Rosa Parks Bus and JFK's limo.
The birthplace of the Motown Sound, this museum offers a glimpse into music history with artifacts and tours of the original studio.
A bustling market district known for fresh produce, unique shops, and murals.
The cultural and business heart of Detroit, featuring skyscrapers, parks, and attractions.
A lively neighborhood known for its Greek eateries, vibrant nightlife, and casinos.
A Detroit classic, the Coney Dog is a hot dog topped with beef chili, onions, and mustard. It's a staple of local cuisine and a must-try for visitors.
Known for its rectangular shape, thick crust, and crispy edges, Detroit-style pizza stands out with cheese that extends to the edges of the pan.
A refreshing drink made with Vernors ginger ale and vanilla ice cream, this float is a local favorite during the summer.
This downtown spot is known for its inventive brunch menu and laid-back vibe, popular with both locals and tourists.
Famous for its slow-cooked BBQ, Slows Bar BQ offers a casual atmosphere with a selection of craft beers.
A staple in Detroit's Greektown, Pegasus Taverna serves authentic Greek cuisine in a lively setting.
Detroit offers moderate pricing, with reasonable accommodation and dining costs compared to other US cities.
15-20% in restaurants, round up change for taxis, tips appreciated in cafes.
Find answers to the most common questions about traveling from St. Louis, MO to Detroit, MI by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

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