Travel Information
Compare bus, train, and flight for St. Louis, MO to Detroit, MI
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from €60. For those with little time consider booking a train which can get you there in 10h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of €60, and a train costs an average of €66.
Distance: 454 miles (731 km)
Compare train with
Most popular Train | Bus |
|---|---|
€138 Average price | €101 Average price Cheapest |
10h 57m Average total duration Fastest 10h 27m Onboard + 30m Additional time* | 13h 37m Average total duration 13h 7m Onboard + 30m Additional time* |
0.2 - 0.7kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom St. Louis, MO to Detroit, MI
How to get from St. Louis, MO to Detroit, MI by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Detroit, MI is by taking a bus because it’s the best combination of price and speed.

Cheapest

Fastest

Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from St. Louis, MO to Detroit, MI
Travel to Detroit, MI easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Detroit, MI.

This is compared to other travel options from St. Louis, MO to Detroit, MI:
A bus is $8 (€6) less than a train for this route with tickets for a train from St. Louis, MO to Detroit, MI costing on average $83 (€66).
A bus is $31 (€25) less than a flight for this route with tickets for a flight from St. Louis, MO to Detroit, MI costing on average $106 (€85).
Other travel options to Detroit, MI take longer:
Train takes on average 13h 5m.
Bus takes on average 13h 10m.
- Around 39 flights per day.
- Around 6 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between St. Louis, MO and Detroit, MI as scheduled services by bus, train, and flight can vary by season or day of the week.
- Buses mostly depart from St. Louis, S 15th St (Civic center) and arrive in Detroit, Greyhound Terminal.
- Trains mostly depart from St. Louis Station, St. Louis, MO and arrive in Detroit Amtrak, Detroit, MI.
- Flights mostly depart from St. Louis Lambert International Airport and arrive in Detroit Wayne County Airport.
- Travel with Amtrak to go to Detroit, MI by train.
- Travel with Greyhound to go to Detroit, MI by bus.
Travelling from St. Louis, MO to Detroit, MI: related information
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