Travel Information to Detroit, MI from St. Louis, MO
| 453 miles (731 km) | |
| Bus, train or flight | |
| $60 - $95 | |
| Bus • $60 (€54) • 12 h 40 min | |
| Flight • $95 (€86) • 4 h 43 min | |
| Greyhound or Amtrak |
Travel 453 miles (731 km) by bus, train or flight between St. Louis, MO and Detroit, MI. The most popular travel companies which serve this route are Greyhound or Amtrak among others. Travelers can even take a direct bus or train from St. Louis, MO to Detroit, MI.
Travel optionsfrom St. Louis, MO to Detroit, MI
How to get from St. Louis, MO to Detroit, MI by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Detroit, MI is by taking a bus because it’s the best combination of price and speed.
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FAQs: Travel from St. Louis, MO to Detroit, MI
Travel to Detroit, MI easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Detroit, MI.

There are 3 travel options from St. Louis, MO to Detroit, MI: bus, train or flight.
The cheapest way to get from St. Louis, MO to Detroit, MI is by taking a bus with average ticket prices of $60 (€54) compared to other travel options to Detroit, MI:
A bus is $35 (€32) less than a flight for this route with tickets for a flight from St. Louis, MO to Detroit, MI costing on average $95 (€86).
Taking a bus costs $17 (€15) less than taking a train, which average ticket prices of $77 (€69).
The fastest way to get to Detroit, MI from St. Louis, MO is by flight with an average travel time of 4 h 43 min.
Other travel options to Detroit, MI take longer:
Getting to Detroit, MI by bus takes 12 h 40 min on average.
Taking a train requires on average 13 h 5 min of travel time.
You should expect to travel around 453 miles (731 km) between St. Louis, MO and Detroit, MI.
The average frequency per day from St. Louis, MO to Detroit, MI is:
- Around 7 buses per day.
- Around 13 flights per day.
- 6 trains per day.
However, we recommend checking specific travel dates for your journey to Detroit, MI from St. Louis, MO as scheduled services by bus, train or flight can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from St. Louis, MO to Detroit, MI:
Omio works with many trusted partners that can help you travel the best way from St. Louis, MO to Detroit, MI:
- You can go to Detroit, MI from St. Louis, MO by bus with Greyhound. You'll see cheap bus tickets for $60 (€54) with Greyhound from St. Louis, MO to Detroit, MI on Omio.
- You can travel by train between St. Louis, MO and Detroit, MI with Amtrak, and you can find Amtrak St. Louis, MO to Detroit, MI tickets for $77 (€69) on Omio.
Yes, there are direct routes from St. Louis, MO to Detroit, MI with the following travel companies:
- You can take a direct bus with.
- You can take a direct train with.
Direct services to Detroit, MI tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your trip.
Travelling from St. Louis, MO to Detroit, MI: related information
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