Travel Information
Compare train, bus, and flight for St. Louis, MO to Detroit, MI
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Detroit, MI among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €81 For those with little time, consider booking a flight, which has an average total journey time of 6h 26m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of €81, while a flight costs an average of €489.
Distance: 454 miles (731 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
€81 Average price Cheapest | €489 Average price | €152 Average price | €87 Average price (fuel + tolls) |
12h 59m Average total duration 12h 29m Onboard + 30m Additional time* | 6h 26m Average total duration Fastest 4h 26m Onboard + 2h 0m Additional time* | 11h 11m Average total duration 10h 41m Onboard + 30m Additional time* | 7h 46m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.4kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to Detroit, MI:
A bus is €34 less than a train for this route with tickets for a train from St. Louis, MO to Detroit, MI costing on average €105.
A bus is €156 less than a flight for this route with tickets for a flight from St. Louis, MO to Detroit, MI costing on average €226.
Other travel options to Detroit, MI take longer:
Train takes on average 10h 58m.
Bus takes on average 13h 19m.
Tickets start at around €105 compared to roughly €87 in fuel and tolls — a saving of about €-17.73. The journey takes 10h 28m versus 7h 46m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom St. Louis, MO to Detroit, MI
How to get from St. Louis, MO to Detroit, MI by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Detroit, MI is by taking a bus because it’s the best combination of price and speed.
· 8:45 AM13h10St. Louis, S 15th St (Civic center)10:55 PMDetroit, Greyhound Terminal€661One-way1 transfer
Cheapest
· 8:45 AM13h10St. Louis, S 15th St (Civic center)10:55 PMDetroit, Greyhound Terminal€661One-way1 transfer
Fastest
· 8:45 AM13h10St. Louis, S 15th St (Civic center)10:55 PMDetroit, Greyhound Terminal€661One-way1 transfer
Other options
· 2:00 AM13h50St. Louis, S 15th St (Civic center)4:50 PMDetroit, Greyhound Terminal€661One-way1 transfer
FlixBus+
2:30 PM15h20St. Louis, S 15th St (Civic center)6:50 AMDetroit, Greyhound Terminal€661One-way1 transfer
FlixBus+
11:30 PM14h15St. Louis, S 15th St (Civic center)2:45 PMDetroit, Greyhound Terminal€681One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from St. Louis, MO to Detroit, MI
Travel to Detroit, MI easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Detroit, MI.

This is compared to other travel options from St. Louis, MO to Detroit, MI:
A bus is €70 less than a train for this route with tickets for a train from St. Louis, MO to Detroit, MI costing on average €152.
A bus is €408 less than a flight for this route with tickets for a flight from St. Louis, MO to Detroit, MI costing on average €489.
Other travel options to Detroit, MI take longer:
Train takes on average 11h 11m.
Bus takes on average 12h 59m.
- Around 51 flights per day.
- Around 4 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between St. Louis, MO and Detroit, MI as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from St. Louis, S 15th St (Civic center) and arrive in Detroit, Greyhound Terminal.
- Trains mostly depart from St. Louis Station, St. Louis, MO and arrive in Detroit Amtrak, Detroit, MI.
- Flights mostly depart from St. Louis Lambert International Airport and arrive in Detroit Wayne County Airport.
- Travel with Amtrak to go to Detroit, MI by train.
- Travel with Greyhound to go to Detroit, MI by bus.
- Travel with United to go to Detroit, MI by flight.
Travelling from St. Louis, MO to Detroit, MI: related information
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