- Must visit
Millyard Museum
Museum inside a former textile mill with exhibits on workers, machines, and city growth. Essential for understanding Manchester's past.
Take a bus from St. Louis, MO to Manchester, NH and enjoy the approximately 1022 miles (1646 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 02:00, the last at 23:30.
Distance 1022 miles (1646 km) |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from St. Louis, MO to Manchester, NH.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:00AM | Arrival Time 07:05PM | Duration 35h05 | Departure days Wed | Cheapest price L 667 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 12:10PM | Duration 41h15 | Departure days Thu | Cheapest price L 844 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 01:10PM | Duration 41h15 | Departure days Sat, Sun | Cheapest price L 659 |
Discover the best of Manchester, NH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester, NH trip today.
Museum inside a former textile mill with exhibits on workers, machines, and city growth. Essential for understanding Manchester's past.
Hands-on art museum and studio space with rotating exhibitions, classes, and local creative programming in downtown Manchester.
Compact aviation museum at Manchester-Boston Regional Airport with aircraft, simulators, and New Hampshire flight history exhibits.
Main downtown street lined with shops, theaters, and historic facades. A practical area for strolling and experiencing city life.
Compact district of restored brick mills, offices, paths, and river views. A distinctive area to explore Manchester's industrial character.
Riverfront park with broad lawns, event spaces, and paths beside the Merrimack. Popular for walks, festivals, and skyline views.
New England clam chowder is a creamy soup of clams, potatoes, and salt pork. It is a regional staple across coastal New England and commonly served in Manchester.
Lobster roll features chilled lobster meat in a buttered split-top bun, often lightly dressed. It is a classic New England summer seafood sandwich.
Johnnycakes are cornmeal griddle cakes long associated with New England cookery. They reflect early regional food traditions and are eaten plain or with butter and syrup.
Classic steakhouse serving steaks, seafood, and cocktails in a polished, traditional setting suited to business dinners or evenings out.
Casual local favorite known for wood-fired pizza, craft beer, and a lively neighborhood atmosphere in downtown Manchester.
Popular casual restaurant focused on Southern-style barbecue, smoked meats, and comfort sides in a relaxed, family-friendly space.
Moderate for the U.S.; hotels and dining are mid-priced, while local transit and casual meals are reasonable for most visitors.
Tip 15-20% at restaurants, about 10-15% for taxis, and $1-2 for cafe drinks if there is table service.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Manchester, NH.
Find answers to the most common questions about traveling from St. Louis, MO to Manchester, NH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, NH, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Manchester, NH buses use the St. Louis, S 15th St (Civic center) to Manchester, Elm St (Veterans Memorial Park) station pair, with some services arriving at Manchester, Boston Manchester Airport. Use this guide to compare St. Louis, MO and Manchester, NH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Manchester, Elm St (Veterans Memorial Park) is 1 km from Manchester city centre. Public transport options include:
Manchester, Elm St (Veterans Memorial Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several nearby options
Wi-Fi is available at Manchester, Elm St (Veterans Memorial Park). ATMs are available at Manchester, Elm St (Veterans Memorial Park).
Ticket office support is available at Manchester, Elm St (Veterans Memorial Park).
Available at Manchester, Elm St (Veterans Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Elm St (Veterans Memorial Park): Wheelchair accessible.
Manchester, Boston Manchester Airport is 7 km from Manchester city centre. Public transport options include:
Manchester, Boston Manchester Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: There are dining options available in the terminal.
Free WiFi is available within the airport terminals. ATMs are aTMs are located in the terminal for cash withdrawals.
Ticket office support is available at Manchester, Boston Manchester Airport.
Available at Manchester, Boston Manchester Airport: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Boston Manchester Airport: The airport is fully accessible with facilities for disabled passengers.
Check bus stations information for St. Louis, MO and Manchester, NH, including where buses depart and arrive on this route.
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