- Must visit
Currier Museum of Art
Manchester’s leading art museum, known for European and American collections, decorative arts, and Frank Lloyd Wright house tours.
Cheapest price
$159
Average price
$159
Fastest journey
1 d 17 h 15 m
Average duration
1 d 17 h 15 m
Buses per day
1
Distance
1646 km
The best way to find a cheap bus ticket from St. Louis, MO to Manchester, NH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Manchester, NH will cost around $159 if you buy it on the day, but the cheapest tickets can be found for only $159.
Of the 1 buses that leave St. Louis, MO for Manchester, NH on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 1646 km distance in an average of 1 d 17 h 15 m but if you time it right, some buses will get you there in just 1 d 17 h 15 m .
On Sat, Jun 20 the slowest buses will take 1 d 17 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Manchester, NH among Omio's users. If you are prioritising price take the bus with prices starting from $141. For those with little time consider booking a flight which can get you there in 9h 50m. The ticket price range depends on the travel mode: a bus costs an average of $141, and a flight costs an average of $517.
Distance: 1022 miles (1646 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$156 Average price Cheapest | $616 Average price | $234 Average price (fuel + tolls) |
40h 13m Average total duration 39h 43m Onboard + 30m Additional time* | 12h 50m Average total duration Fastest 9h 50m Onboard + 3h 0m Additional time* | 18h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Manchester, NH:
A bus is $460 (€376) less than a flight for this route with tickets for a flight from St. Louis, MO to Manchester, NH costing on average $616 (€504).
Other travel options to Manchester, NH take longer:
Bus takes on average 39h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:00AM | Arrival Time 07:05PM | Duration 35h05 | Departure days Wed | Cheapest price $143 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 12:10PM | Duration 41h15 | Departure days Thu | Cheapest price $181 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 01:10PM | Duration 41h15 | Departure days Sat, Sun | Cheapest price $141 |
The table below shows live departures for St. Louis, MO to Manchester, NH buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 PM St. Louis, MO | 41h15 | 1:10 PM Manchester, NH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Manchester, NH run on average 5 times per day, taking around 39h 43m. Cheap bus tickets for this journey start at $141 (€116) if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 1022 miles (1646 km) distance in 35h 5m.
Distance 1022 miles (1646 km) |
Average bus duration 39h 43m |
Cheapest ticket price $141 (€116) |
Buses per day 5 |
Fastest bus 35h 5m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Manchester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester trip today.
Manchester’s leading art museum, known for European and American collections, decorative arts, and Frank Lloyd Wright house tours.
Local history museum in the Amoskeag Millyard covering Manchester’s industrial, immigrant, and community story.
Hands-on science museum with interactive exhibits and a large LEGO model of the city’s historic mills.
Manchester’s main downtown street, lined with shops, theaters, and city life, ideal for a first walk through the center.
Historic mill district along the Merrimack River, popular for red-brick industrial architecture and local history.
Large city park with walking paths, pond views, and seasonal recreation that makes it a local favorite.
Locally produced maple syrup is a classic New England staple, enjoyed on pancakes, waffles, and in seasonal treats across New Hampshire.
A beloved New England fall specialty, these cake-style donuts are flavored with apple cider and often coated in cinnamon sugar.
A regional coastal favorite often found in southern New Hampshire, featuring chilled lobster meat in a buttered split-top roll.
A respected steakhouse offering classic chops, seafood, and a clubby fine-dining atmosphere popular for special occasions.
An established upscale-casual restaurant in downtown Manchester known for creative American cuisine, polished service, and a lively atmosphere.
A well-known riverside restaurant and event venue serving refined American dishes in a historic mill setting with scenic views.
Costs are moderate by U.S. standards. Chain hotels and casual dining are fairly priced, but downtown stays and upscale restaurants cost more.
Tip 18-20% at sit-down restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5 as appropriate.
Find answers to the most common questions about traveling from St. Louis, MO to Manchester, NH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, NH, this guide helps you travel smarter and with confidence.

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