- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Cheapest price
$139
Average price
$223
Fastest journey
1 d 6 h 30 m
Average duration
1 d 7 h 37 m
Buses per day
6
Distance
1691 km
The best way to find a cheap bus ticket from San Antonio, TX to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Chicago, IL will cost around $223 if you buy it on the day, but the cheapest tickets can be found for only $139.
Of the 6 buses that leave San Antonio, TX for Chicago, IL on Fri, Jul 31, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 31 the direct buses cover the 1691 km distance in an average of 1 d 7 h 37 m but if you time it right, some buses will get you there in just 1 d 6 h 30 m .
On Fri, Jul 31 the slowest buses will take 1 d 8 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the train as it is the most popular option from San Antonio, TX to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $114. For those with little time consider booking a flight which can get you there in 4h 45m. The ticket price range depends on the travel mode: a bus costs an average of $114, and a flight costs an average of $119.
Distance: 1050 miles (1691 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$238 Average price Cheapest | $271 Average price | $334 Average price | $246 Average price (fuel + tolls) |
26h 21m Average total duration 25h 51m Onboard + 30m Additional time* | 31h 11m Average total duration 30h 41m Onboard + 30m Additional time* | 7h 45m Average total duration Fastest 4h 45m Onboard + 3h 0m Additional time* | 18h 3m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Chicago, IL:
A bus is $32 (€26) less than a train for this route with tickets for a train from San Antonio, TX to Chicago, IL costing on average $271 (€222).
A bus is $96 (€78) less than a flight for this route with tickets for a flight from San Antonio, TX to Chicago, IL costing on average $334 (€274).
Other travel options to Chicago, IL take longer:
Bus takes on average 25h 51m.
Train takes on average 30h 41m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 09:10AM | Duration 32h55 | Departure days Wed | Cheapest price $221 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 10:10AM | Duration 32h55 | Departure days Wed | Cheapest price $317 |
Operator Greyhound | Departure Time 01:30AM | Arrival Time 04:20AM | Duration 26h50 | Departure days Mon, Thu | Cheapest price $179 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 09:20AM | Duration 31h20 | Departure days Thu | Cheapest price $231 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 09:10AM | Duration 30h55 | Departure days Mon, Thu, Sat | Cheapest price $236 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 02:00PM | Duration 34h45 | Departure days Mon, Sat, Sun | Cheapest price $316 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:15PM | Duration 33h25 | Departure days Mon, Thu | Cheapest price $180 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 09:20AM | Duration 26h50 | Departure days Tue, Fri, Sat, Sun | Cheapest price $139 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 10:10AM | Duration 26h40 | Departure days Mon, Wed, Thu | Cheapest price $180 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 04:05PM | Duration 32h20 | Departure days Mon, Thu | Cheapest price $181 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 08:15PM | Duration 33h25 | Departure days Sun | Cheapest price $300 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 08:15PM | Duration 32h25 | Departure days Sun | Cheapest price $321 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 08:10PM | Duration 31h35 | Departure days Mon, Thu | Cheapest price $178 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 09:05PM | Duration 32h20 | Departure days Fri, Sat, Sun | Cheapest price $132 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 10:30PM | Duration 32h45 | Departure days Fri, Sat, Sun | Cheapest price $146 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 01:10AM | Duration 31h35 | Departure days Tue, Wed, Sat | Cheapest price $255 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 02:10AM | Duration 31h35 | Departure days Wed, Fri, Sun | Cheapest price $134 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 04:20AM | Duration 31h20 | Departure days Thu | Cheapest price $311 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 08:00AM | Duration 34h05 | Departure days Mon | Cheapest price $163 |
The table below shows live departures for San Antonio, TX to Chicago, IL buses for today, Thursday, July 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 26h50 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 30h30 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
· · | 5:50 AM San Antonio, N St Mary's St (Greyhound), TX | 33h25 | 3:15 PM Chicago, Greyhound Bus Station | 2 transfers | |
FlixBus · FlixBus+ + FlixBus | 7:30 AM San Antonio, N St Mary's St (Greyhound), TX | 32h35 | 4:05 PM Chicago, Greyhound Bus Station | 3 transfers | |
FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 48h15 | 8:00 AM Chicago, Union Station (Amtrak), IL | 4 transfers | |
FlixBus · FlixBus+ + FlixBus | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 32h20 | 4:05 PM Chicago, Greyhound Bus Station | 3 transfers | |
· · | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 31h35 | 8:10 PM Chicago, Greyhound Bus Station | 2 transfers | |
· +![]() | 9:00 PM San Antonio, N St Mary's St (Greyhound), TX | 31h20 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
· +![]() | 9:00 PM San Antonio, N St Mary's St (Greyhound), TX | 35h00 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| Friday, July 31 | |||||
![]() | 2:15 AM San Antonio, TX | 30h55 | 9:10 AM Chicago, IL | 0 transfersDirect | |
![]() | 3:15 AM San Antonio, TX | 34h45 | 2:00 PM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to Chicago, IL run on average 8 times per day, taking around 25h 51m. Cheap bus tickets for this journey start at $114 (€94) if you book in advance.
The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 1050 miles (1691 km) distance in 26h 40m.
Distance 1050 miles (1691 km) |
Average bus duration 25h 51m |
Cheapest ticket price $114 (€94) |
Buses per day 8 |
Fastest bus 26h 40m |
First bus 12:15 AM |
Last bus 11:10 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 49 days |
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from San Antonio, TX to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Chicago, IL buses use the San Antonio, N St Mary's St (Greyhound) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare San Antonio, TX and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need