The cheapest and fastest buses from San Antonio, TX to Chicago, IL
Cheapest price
$179
Average price
$218
Fastest journey
1 d 7 h 30 m
Average duration
1 d 8 h 20 m
Buses per day
2
Distance
1691 km
The best way to find a cheap bus ticket from San Antonio, TX to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Chicago, IL will cost around $218 if you buy it on the day, but the cheapest tickets can be found for only $179.
Of the 2 buses that leave San Antonio, TX for Chicago, IL on Sat, Jan 31, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jan 31 the direct buses cover the 1691 km distance in an average of 1 d 8 h 20 m but if you time it right, some buses will get you there in just 1 d 7 h 30 m .
On Sat, Jan 31 the slowest buses will take 1 d 9 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for San Antonio, TX to Chicago, IL
Omio recommends booking the train as it is the most popular option from San Antonio, TX to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €109. For those with little time consider booking a flight which can get you there in 4h 4m. The ticket price range depends on the travel mode: a bus costs an average of €109, and a flight costs an average of €209.
Distance: 1050 miles (1691 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€178 Average price Cheapest | €186 Average price | €320 Average price |
24h 53m Average total duration 24h 23m Onboard + 30m Additional time* | 30h 57m Average total duration 30h 27m Onboard + 30m Additional time* | 7h 4m Average total duration Fastest 4h 4m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
San Antonio, TX to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 08:00AM | Duration 30h30 | Departure days Wed, Thu, Fri, Sun | Cheapest price $189 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:15PM | Duration 33h25 | Departure days Wed, Thu, Fri, Sun | Cheapest price $191 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 04:30PM | Duration 33h00 | Departure days Thu, Fri, Sun | Cheapest price $195 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 11:30AM | Duration 51h45 | Departure days Wed | Cheapest price $281 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 04:30PM | Duration 32h45 | Departure days Thu, Fri, Sun | Cheapest price $189 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 08:10PM | Duration 31h35 | Departure days Wed, Thu, Fri, Sun | Cheapest price $189 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 04:10AM | Duration 30h55 | Departure days Wed, Thu, Fri, Sun | Cheapest price $189 |
Live departures
San Antonio, TX to Chicago, IL bus times
The table below shows live departures for San Antonio, TX to Chicago, IL buses for today, Friday, January 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined · undefined | 11:50 AM San Antonio, N St Mary's St (Greyhound), TX | 33h25 | 9:15 PM Chicago, Greyhound Bus Station | 2 transfers | |
FlixBus · FlixBus+ + FlixBus | 1:30 PM San Antonio, N St Mary's St (Greyhound), TX | 33h00 | 10:30 PM Chicago, Greyhound Bus Station | 3 transfers | |
FlixBus · FlixBus+ + FlixBus | 1:45 PM San Antonio, Avenue A / Pearl Pkwy, TX | 32h45 | 10:30 PM Chicago, Greyhound Bus Station | 3 transfers | |
FlixBus · FlixBus+ undefined · undefined | 1:45 PM San Antonio, Avenue A / Pearl Pkwy, TX | 48h15 | 2:00 PM Chicago, Union Station (Amtrak), IL | 4 transfers | |
undefined · undefined · undefined | 6:35 PM San Antonio, N St Mary's St (Greyhound), TX | 31h35 | 2:10 AM Chicago, Greyhound Bus Station | 2 transfers | |
+ undefined · undefined | 3:15 AM San Antonio, N St Mary's St (Greyhound), TX | 30h55 | 10:10 AM Chicago, Greyhound Bus Station | 2 transfers | |
+ undefined · undefined | 3:15 AM San Antonio, N St Mary's St (Greyhound), TX | 34h45 | 2:00 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 31
Feb 01
Feb 02
Feb 03
Feb 04
Feb 05
Feb 06
Why should you book San Antonio, TX to Chicago, IL buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from San Antonio, TX to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Antonio, TX to Chicago, IL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Antonio, TX to Chicago, IL.
Journey information
Overview: Bus from San Antonio, TX to Chicago, IL
Buses from San Antonio, TX to Chicago, IL run on average 7 times per day, taking around 24h 23m. Cheap bus tickets for this journey start at $138 (€109) if you book in advance.
The earliest bus runs at 00:15, the last at 22:30. The fastest bus covers the 1050 miles (1691 km) distance in 31h 30m.
Distance 1050 miles (1691 km) |
Average bus duration 24h 23m |
Cheapest ticket price $138 (€109) |
Buses per day 7 |
Fastest bus 31h 30m |
First bus 00:15 |
Last bus 22:30 |
Bus providers: Greyhound from San Antonio, TX to Chicago, ILYou can travel by bus between San Antonio, TX to Chicago, IL with Greyhound for as low as $138 (€109). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Antonio, TX to Chicago, IL
Find answers to the most common questions about traveling from San Antonio, TX to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Antonio, TX to Chicago, IL
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Chicago, IL
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