1,000+ travel companies
1,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from San Antonio, TX to Chicago, IL
Showing times and prices for Mar 17
Cheapest price
$254
Average price
$280
Fastest journey
1 d 2 h 40 m
Average duration
1 d 7 h 1 m
Buses per day
6
Distance
1691 km
Cheap tickets
The best way to find a cheap bus ticket from San Antonio, TX to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Chicago, IL will cost around $280 if you buy it on the day, but the cheapest tickets can be found for only $254.
Fast buses
It's difficult to get from San Antonio, TX to Chicago, IL without transferring at least 2 times.
undefined · undefined · undefined12:35PM31h35
San Antonio, N St Mary's St (Greyhound), TX08:10PMChicago, Greyhound Bus Station
$2541One-way
2 transfers
undefined · undefined · undefined · undefined07:15PM32h55
San Antonio, N St Mary's St (Greyhound), TX04:10AMChicago, Greyhound Bus Station
$2541One-way
3 transfers
undefined · undefined · undefined01:30AM26h40
San Antonio, N St Mary's St (Greyhound), TX04:10AMChicago, Greyhound Bus Station
$2581One-way
2 transfers
undefined · undefined · undefined05:50AM33h25
San Antonio, N St Mary's St (Greyhound), TX03:15PMChicago, Greyhound Bus Station
$2591One-way
2 transfers
undefined · undefined · undefined01:30AM30h30
San Antonio, N St Mary's St (Greyhound), TX08:00AMChicago, Union Station (Amtrak), IL
$2951One-way
2 transfers
undefined · undefined · undefined01:30AM26h40
San Antonio, N St Mary's St (Greyhound), TX04:10AMChicago, Greyhound Bus Station
$2581One-way
2 transfers
undefined · undefined · undefined01:30AM30h30
San Antonio, N St Mary's St (Greyhound), TX08:00AMChicago, Union Station (Amtrak), IL
$2951One-way
2 transfers
undefined · undefined · undefined12:35PM31h35
San Antonio, N St Mary's St (Greyhound), TX08:10PMChicago, Greyhound Bus Station
$2541One-way
2 transfers
undefined · undefined · undefined · undefined07:15PM32h55
San Antonio, N St Mary's St (Greyhound), TX04:10AMChicago, Greyhound Bus Station
$2541One-way
3 transfers
undefined · undefined · undefined05:50AM33h25
San Antonio, N St Mary's St (Greyhound), TX03:15PMChicago, Greyhound Bus Station
$2591One-way
2 transfers
Travel Information
Compare train, bus, and flight for San Antonio, TX to Chicago, IL
Omio recommends booking the train as it is the most popular option from San Antonio, TX to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $150. For those with little time consider booking a flight which can get you there in 4h 4m. The ticket price range depends on the travel mode: a train costs an average of $150, and a flight costs an average of $105.
Distance: 1050 miles (1691 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$255 Average price | $240 Average price Cheapest | $308 Average price |
26h 7m Average total duration 25h 37m Onboard + 30m Additional time* | 31h 7m Average total duration 30h 37m Onboard + 30m Additional time* | 7h 4m Average total duration Fastest 4h 4m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
San Antonio, TX to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 04:10AM | Duration 26h40 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $232 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:15PM | Duration 33h25 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $230 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 04:30PM | Duration 33h00 | Departure days Mon | Cheapest price $358 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 11:30AM | Duration 51h45 | Departure days Wed | Cheapest price $261 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 08:10PM | Duration 36h25 | Departure days Mon, Thu, Fri | Cheapest price $222 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 08:10PM | Duration 31h35 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $220 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 04:10AM | Duration 32h55 | Departure days Mon, Tue | Cheapest price $254 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 04:10AM | Duration 30h55 | Departure days Wed, Thu, Fri | Cheapest price $222 |
Live departures
San Antonio, TX to Chicago, IL bus times
The table below shows live departures for San Antonio, TX to Chicago, IL buses for today, Monday, March 16. You can also manually refresh the results below to see updated bus journeys.
Last updated at 3:07 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| undefined · undefined · undefined | 5:35 PM San Antonio, N St Mary's St (Greyhound), TX | 31h35 | 1:10 AM Chicago, Greyhound Bus Station | 2 transfers | |
| Tuesday, March 17 | |||||
| undefined · undefined · undefined | 12:15 AM San Antonio, N St Mary's St (Greyhound), TX | 36h45 | 1:00 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| undefined · undefined · undefined · undefined | 12:15 AM San Antonio, N St Mary's St (Greyhound), TX | 32h55 | 9:10 AM Chicago, Greyhound Bus Station | 3 transfers | |
| undefined · undefined · undefined | 6:30 AM San Antonio, N St Mary's St (Greyhound), TX | 26h40 | 9:10 AM Chicago, Greyhound Bus Station | 2 transfers | |
| undefined · undefined · undefined | 6:30 AM San Antonio, N St Mary's St (Greyhound), TX | 30h30 | 1:00 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| undefined · undefined · undefined | 10:50 AM San Antonio, N St Mary's St (Greyhound), TX | 33h25 | 8:15 PM Chicago, Greyhound Bus Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Tue
Mar 17
Mar 17
Wed
Mar 18
Mar 18
Thu
Mar 19
Mar 19
Fri
Mar 20
Mar 20
Sat
Mar 21
Mar 21
Sun
Mar 22
Mar 22
Mon
Mar 23
Mar 23
Tue
Mar 24
Mar 24
Wed
Mar 25
Mar 25
Thu
Mar 26
Mar 26
Fri
Mar 27
Mar 27
Sat
Mar 28
Mar 28
Sun
Mar 29
Mar 29
Mon
Mar 30
Mar 30
Why should you book San Antonio, TX to Chicago, IL buses with Omio?
Greyhound operates all buses services from San Antonio, TX to Chicago, IL.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Chicago, IL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Antonio, TX to Chicago, IL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Antonio, TX to Chicago, IL.
Journey information
Overview: Bus from San Antonio, TX to Chicago, IL
USAUSA
Buses from San Antonio, TX to Chicago, IL run on average 8 times per day, taking around 25h 37m. Cheap bus tickets for this journey start at $134 (€110) but you can travel from only $105 (€86) by flight.
The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 1050 miles (1691 km) distance in 26h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $105 (€86)
Distance 1050 miles (1691 km) |
Average bus duration 25h 37m |
Cheapest ticket price $134 (€110) |
Buses per day 8 |
Fastest bus 26h 40m |
First bus 00:15 |
Last bus 23:10 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $105 (€86)
Bus providers: Greyhound from San Antonio, TX to Chicago, ILYou can travel by bus between San Antonio, TX to Chicago, IL with Greyhound for as low as $105 (€86). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
26h 40m
Cheapest Price
$134 (€110)
Greyhound frequency
7 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from San Antonio, TX to Chicago, IL
Find answers to the most common questions about traveling from San Antonio, TX to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Antonio, TX to Chicago, IL can start from as little as $134 (€110) when you book in advance. The average bus ticket price for San Antonio, TX to Chicago, IL is $255 (€209) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Antonio, TX to Chicago, IL is 26h 40m to travel the 1050 miles (1691 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Antonio, TX to Chicago, IL leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Chicago, IL leaves at 11:10 PM.
There are 8 buses a day from San Antonio, TX to Chicago, IL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Antonio, TX to Chicago, IL, you can count on Greyhound for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between San Antonio, TX and Chicago, IL and compare the amenities they offer before buying a bus ticket.
A trip to Chicago, IL from San Antonio, TX is worth doing but not as a day trip with a journey time of 26h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Antonio, TX to Chicago, IL is October.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Chicago, IL including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from San Antonio, TX to Chicago, IL for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Chicago, IL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
Whether you can cancel your bus ticket from San Antonio, TX to Chicago, IL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Chicago, IL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Chicago, IL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Antonio, TX to Chicago, IL.
You can reserve your seat on the bus from San Antonio, TX to Chicago, IL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Antonio, TX to Chicago, IL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Antonio, TX to Chicago, IL with the following bus company: Greyhound.
popular bus stations
Popular bus stations from San Antonio, TX to Chicago, IL
San Antonio
Chicago
The major bus station for departures in San Antonio is San Antonio, N St Mary's St (Greyhound). Find all the information you need to know about services, amenities and connections at San Antonio, N St Mary's St (Greyhound) for your trip from San Antonio to Chicago.
San Antonio, N St Mary's St (Greyhound)
information
San Antonio, Avenue A / Pearl Pkwy
information
The major bus station for arrivals in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip to Chicago from San Antonio.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
More options for your journey from San Antonio, TX to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and San Antonio, TX
Most popular bus connections to Chicago, IL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
