- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Cheapest price on Sep 14
€133
Average ticket price on Sep 14
€142
Fastest journey on Sep 14
1 d 2 h 50 m
Average journey duration on Sep 14
1 d 6 h 5 m
Buses on Sep 14
10
Distance
1691 km
The best way to find a cheap bus ticket from San Antonio, TX to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Chicago, IL will cost around €142 if you buy it on the day, but the cheapest tickets can be found for only €133.
It's difficult to get from San Antonio, TX to Chicago, IL without transferring at least 2 times.
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· · Omio recommends booking the train as it is the most popular option from San Antonio, TX to Chicago, IL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €208 For those with little time, consider booking a flight, which has an average total journey time of 7h 15m. Average ticket prices depend on the travel mode: a bus costs an average of €208, while a flight costs an average of €469.
Distance: 1050 miles (1691 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€208 Average price Cheapest | €271 Average price | €469 Average price | €204 Average price (fuel + tolls) |
28h 36m Average total duration 28h 6m Onboard + 30m Additional time* | 30h 41m Average total duration 30h 11m Onboard + 30m Additional time* | 7h 15m Average total duration Fastest 5h 15m Onboard + 2h 0m Additional time* | 18h 3m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Chicago, IL:
A bus is €63 less than a train for this route with tickets for a train from San Antonio, TX to Chicago, IL costing on average €271.
A bus is €260 less than a flight for this route with tickets for a flight from San Antonio, TX to Chicago, IL costing on average €469.
Other travel options to Chicago, IL take longer:
Bus takes on average 28h 6m.
Train takes on average 30h 11m.
Tickets start at around €208 compared to roughly €204 in fuel and tolls — a saving of about €-3.83. The journey takes 28h 6m versus 18h 3m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 08:00AM | Duration 30h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price €122 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 09:10AM | Duration 29h55 | Departure days Sun | Cheapest price €267 |
Operator Greyhound | Departure Time 04:20AM | Arrival Time 03:15PM | Duration 34h55 | Departure days Tue | Cheapest price €135 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 11:30AM | Duration 31h05 | Departure days Mon | Cheapest price €134 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:15PM | Duration 33h25 | Departure days Fri | Cheapest price €132 |
Operator Greyhound | Departure Time 06:10AM | Arrival Time 03:15PM | Duration 33h05 | Departure days Wed, Thu | Cheapest price €121 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 01:00PM | Duration 30h30 | Departure days Sat | Cheapest price €118 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 04:05PM | Duration 32h35 | Departure days Mon, Thu, Fri, Sun | Cheapest price €135 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 11:30AM | Duration 51h45 | Departure days Wed | Cheapest price €138 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 08:00AM | Duration 48h15 | Departure days Mon, Thu, Fri, Sun | Cheapest price €135 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 08:10PM | Duration 31h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price €122 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 09:05PM | Duration 32h20 | Departure days Sat | Cheapest price €223 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 10:30PM | Duration 32h45 | Departure days Sat | Cheapest price €120 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 01:10AM | Duration 31h35 | Departure days Sat | Cheapest price €209 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 08:00AM | Duration 35h00 | Departure days Wed, Thu | Cheapest price €121 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 08:00AM | Duration 34h05 | Departure days Mon, Tue, Fri, Sun | Cheapest price €133 |
The table below shows live departures for San Antonio, TX to Chicago, IL buses for today, Sunday, September 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+ + FlixBus | 7:30 AM San Antonio, N St Mary's St (Greyhound), TX | 32h35 | 4:05 PM Chicago, Greyhound Bus Station | 3 transfers | |
FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 48h15 | 8:00 AM Chicago, Union Station (Amtrak), IL | 4 transfers | |
FlixBus · FlixBus+ + FlixBus | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 32h20 | 4:05 PM Chicago, Greyhound Bus Station | 3 transfers | |
· · | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 31h35 | 8:10 PM Chicago, Greyhound Bus Station | 2 transfers | |
FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 34h05 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 30h25 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
| Monday, September 14 | |||||
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 26h50 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 30h30 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
+ FlixBus · FlixBus | 4:25 AM San Antonio, N St Mary's St (Greyhound), TX | 31h05 | 11:30 AM Chicago, Greyhound Bus Station | 2 transfers | |
+ FlixBus+![]() | 4:25 AM San Antonio, N St Mary's St (Greyhound), TX | 33h20 | 1:45 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Antonio, TX to Chicago, IL run on average 7 times per day, taking around 28h 6m. Cheap bus tickets for this journey start at €103 but you can travel from only €77 by flight.
The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 1050 miles (1691 km) distance in 22h 30m.
Distance 1050 miles (1691 km) |
Average bus duration 28h 6m |
Cheapest ticket price €103 |
Buses per day 7 |
Fastest bus 22h 30m |
First bus 12:15 AM |
Last bus 11:10 PM |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 14 days |
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from San Antonio, TX to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Chicago, IL buses use the San Antonio, N St Mary's St (Greyhound) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare San Antonio, TX and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack shop and vending machines available
Free Wi-Fi in waiting area. ATMs are located near entrance.
Ticket office support is available at Chicago, Greyhound Bus Station.
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options are available inside the station.
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Chicago, Union Station (Amtrak).
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
Chicago, 95th Red Line Station is 14 km from Chicago city centre. Public transport options include:
Chicago, 95th Red Line Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Chicago, 95th Red Line Station. ATMs are available at Chicago, 95th Red Line Station.
Ticket office support is available at Chicago, 95th Red Line Station.
Available at Chicago, 95th Red Line Station: Parking, Taxis, WC.
Accessibility facilities are available at Chicago, 95th Red Line Station: Wheelchair accessible entrances available.
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