- Must visit
Art Institute Of Chicago
One of the world’s leading art museums, famous for Impressionist masterpieces, American art, and major special exhibitions.
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The cheapest and fastest buses from San Antonio, TX to Chicago, IL
Showing times and prices for Jun 15
Cheapest price
$257
Average price
$313
Fastest journey
1 d 2 h 50 m
Average duration
1 d 6 h 20 m
Buses per day
9
Distance
1691 km
Cheap tickets
The best way to find a cheap bus ticket from San Antonio, TX to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Chicago, IL will cost around $313 if you buy it on the day, but the cheapest tickets can be found for only $257.
Fast buses
It's difficult to get from San Antonio, TX to Chicago, IL without transferring at least 2 times.
FlixBus+
· 9:55 PM30h25San Antonio, N St Mary's St (Greyhound), TX4:20 AMChicago, Greyhound Bus Station$2571One-way2 transfers- · · 12:35 PM31h35San Antonio, N St Mary's St (Greyhound), TX8:10 PMChicago, Greyhound Bus Station$2691One-way2 transfers
- FlixBus · FlixBus++FlixBus7:30 AM32h35San Antonio, N St Mary's St (Greyhound), TX4:05 PMChicago, Greyhound Bus Station$3021One-way3 transfers
- FlixBus · FlixBus++FlixBus7:45 AM32h20San Antonio, Avenue A / Pearl Pkwy, TX4:05 PMChicago, Greyhound Bus Station$3021One-way3 transfers
- FlixBus+ · 9:55 PM34h05San Antonio, N St Mary's St (Greyhound), TX8:00 AMChicago, Union Station (Amtrak), IL$3081One-way2 transfers
- · · 1:30 AM26h50San Antonio, N St Mary's St (Greyhound), TX4:20 AMChicago, Greyhound Bus Station$3231One-way2 transfers
- FlixBus+ · 9:55 PM30h25San Antonio, N St Mary's St (Greyhound), TX4:20 AMChicago, Greyhound Bus Station$2571One-way2 transfers
- · · 1:30 AM30h30San Antonio, N St Mary's St (Greyhound), TX8:00 AMChicago, Union Station (Amtrak), IL$3891One-way2 transfers
- · · 12:35 PM31h35San Antonio, N St Mary's St (Greyhound), TX8:10 PMChicago, Greyhound Bus Station$2691One-way2 transfers
- FlixBus · FlixBus++FlixBus7:45 AM32h20San Antonio, Avenue A / Pearl Pkwy, TX4:05 PMChicago, Greyhound Bus Station$3021One-way3 transfers
Travel Information
Compare train, bus, and flight for San Antonio, TX to Chicago, IL
Omio recommends booking the train as it is the most popular option from San Antonio, TX to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $116. For those with little time consider booking a flight which can get you there in 4h 45m. The ticket price range depends on the travel mode: a bus costs an average of $116, and a flight costs an average of $120.
Distance: 1050 miles (1691 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$241 Average price Cheapest | $273 Average price | $337 Average price | $248 Average price (fuel + tolls) |
26h 21m Average total duration 25h 51m Onboard + 30m Additional time* | 31h 11m Average total duration 30h 41m Onboard + 30m Additional time* | 7h 45m Average total duration Fastest 4h 45m Onboard + 3h 0m Additional time* | 18h 3m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Antonio, TX to Chicago, IL is a bus with an average price of $241 (€196).
This is compared to other travel options from San Antonio, TX to Chicago, IL:
A bus is $32 (€26) less than a train for this route with tickets for a train from San Antonio, TX to Chicago, IL costing on average $273 (€222).
A bus is $97 (€78) less than a flight for this route with tickets for a flight from San Antonio, TX to Chicago, IL costing on average $337 (€274).
The fastest way to travel from San Antonio, TX to Chicago, IL is by flight with an average journey time of 4h 45m.
Other travel options to Chicago, IL take longer:
Bus takes on average 25h 51m.
Train takes on average 30h 41m.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Chicago, IL including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from San Antonio, TX to Chicago, IL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Antonio, TX to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 09:10AM | Duration 32h55 | Departure days Wed | Cheapest price $223 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 10:10AM | Duration 32h55 | Departure days Wed | Cheapest price $320 |
Operator Greyhound | Departure Time 01:30AM | Arrival Time 08:00AM | Duration 30h30 | Departure days Mon, Wed, Thu, Sun | Cheapest price $167 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 09:10AM | Duration 30h55 | Departure days Sat | Cheapest price $239 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 02:00PM | Duration 34h45 | Departure days Sat, Sun | Cheapest price $329 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:15PM | Duration 33h25 | Departure days Mon, Wed, Thu, Sun | Cheapest price $167 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 01:00PM | Duration 30h30 | Departure days Tue, Fri, Sat | Cheapest price $140 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 04:05PM | Duration 32h35 | Departure days Mon, Thu, Sun | Cheapest price $171 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 11:30AM | Duration 51h45 | Departure days Wed | Cheapest price $179 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 04:05PM | Duration 32h20 | Departure days Mon, Thu, Sun | Cheapest price $171 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 08:10PM | Duration 31h35 | Departure days Mon, Wed, Thu, Sun | Cheapest price $171 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 09:05PM | Duration 32h20 | Departure days Fri, Sat | Cheapest price $223 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 10:30PM | Duration 32h45 | Departure days Fri, Sat | Cheapest price $148 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 01:10AM | Duration 31h35 | Departure days Tue, Sat | Cheapest price $258 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 02:10AM | Duration 31h35 | Departure days Fri | Cheapest price $191 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 08:00AM | Duration 35h00 | Departure days Wed, Thu | Cheapest price $170 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 08:00AM | Duration 34h05 | Departure days Mon, Sun | Cheapest price $257 |
Live departures
San Antonio, TX to Chicago, IL bus times
The table below shows live departures for San Antonio, TX to Chicago, IL buses for today, Sunday, June 14. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 34h05 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 30h25 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
| Monday, June 15 | |||||
| · · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 30h30 | 8:00 AM Chicago, Union Station (Amtrak), IL | 2 transfers | |
| · · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 26h50 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
| · · | 5:50 AM San Antonio, N St Mary's St (Greyhound), TX | 33h25 | 3:15 PM Chicago, Greyhound Bus Station | 2 transfers | |
| FlixBus · FlixBus++FlixBus | 7:30 AM San Antonio, N St Mary's St (Greyhound), TX | 32h35 | 4:05 PM Chicago, Greyhound Bus Station | 3 transfers | |
| FlixBus · FlixBus++FlixBus | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 32h20 | 4:05 PM Chicago, Greyhound Bus Station | 3 transfers | |
| FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 48h15 | 8:00 AM Chicago, Union Station (Amtrak), IL | 4 transfers | |
| · · | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 31h35 | 8:10 PM Chicago, Greyhound Bus Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Antonio, TX to Chicago, IL buses with Omio?
Greyhound as well as VIA Metropolitan Transit offer buses services from San Antonio, TX to Chicago, IL.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Chicago, IL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of VIA Metropolitan Transit to find the best option for your trip from San Antonio, TX to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Antonio, TX to Chicago, IL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Antonio, TX to Chicago, IL.
Journey information
Overview: Bus from San Antonio, TX to Chicago, IL
USAUSA
Buses from San Antonio, TX to Chicago, IL run on average 8 times per day, taking around 25h 51m. Cheap bus tickets for this journey start at $116 (€94) if you book in advance.
The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 1050 miles (1691 km) distance in 26h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1050 miles (1691 km) |
Average bus duration 25h 51m |
Cheapest ticket price $116 (€94) |
Buses per day 8 |
Fastest bus 26h 40m |
First bus 12:15 AM |
Last bus 11:10 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, VIA Metropolitan Transit from San Antonio, TX to Chicago, ILYou can travel by bus between San Antonio, TX to Chicago, IL with Greyhound, VIA Metropolitan Transit for as low as $116 (€94). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
26h 40m
Cheapest Price
$116 (€94)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
VIA Metropolitan Transit
Luggage & cancellation policy
Average Duration
24h 46m
Cheapest Price
$327 (€265)
VIA Metropolitan Transit frequency
1 a day
Complete guide to Chicago
Things to do in Chicago
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
- Must visit
Field Museum
Major natural history museum known for Sue the T. rex, ancient cultures, and large family-friendly science exhibits.
- Must visit
Museum Of Science And Industry
Large hands-on science museum in Hyde Park with a U-505 submarine, aviation exhibits, and immersive interactive displays.
- Must visit
Millennium Park
Chicago’s signature public space, home to Cloud Gate and major events, with strong appeal for first-time visitors and photographers.
- Must visit
Chicago Riverwalk
Scenic pedestrian route along the Chicago River, popular for architecture views, strolling, and social-media-friendly city scenes.
- Must visit
Magnificent Mile
Famous stretch of North Michigan Avenue known for landmark architecture, flagship stores, and busy big-city energy.
Deep-Dish Pizza
Chicago’s iconic thick-crust pizza baked in a deep pan with layers of cheese, toppings, and chunky tomato sauce.
Chicago-Style Hot Dog
An all-beef hot dog on a poppy seed bun topped with mustard, onions, relish, tomato, pickle spear, sport peppers, and celery salt.
Italian Beef Sandwich
A classic Chicago sandwich of thin-sliced seasoned beef served on a roll, often dipped in jus and topped with giardiniera or sweet peppers.
The Purple Pig
A well-known Magnificent Mile restaurant serving Mediterranean-influenced small plates, charcuterie, and strong wine selections.
Alinea
Chicago’s internationally acclaimed fine-dining restaurant known for inventive tasting menus and a polished, theatrical experience.
Lou Malnati's Pizzeria
A legendary Chicago pizzeria best known for buttery-crust deep-dish pizza in a casual, family-friendly setting.
United States Dollar
Moderate by U.S. big-city standards. Hotels can be pricey downtown, but food and transit offer good value.
Average meal costs
- Budget
- USD 10-18 for fast food or casual takeout.
- Mid-range
- USD 25-45 per person at a mid-range restaurant.
- Fine dining
- USD 80+ per person before drinks and tip.
- Coffee
- USD 4-7 for a regular café coffee.
Tipping culture
Tip 18-20% at sit-down restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up or 10-15% for taxis, and USD 1-2 per bag for hotel staff.
FAQs: Bus from San Antonio, TX to Chicago, IL
Find answers to the most common questions about traveling from San Antonio, TX to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Antonio, TX to Chicago, IL can start from as little as $116 (€94) when you book in advance. The average bus ticket price for San Antonio, TX to Chicago, IL is $241 (€196) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Antonio, TX to Chicago, IL is 26h 40m to travel the 1050 miles (1691 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Antonio, TX to Chicago, IL leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Chicago, IL leaves at 11:10 PM.
There are 8 buses a day from San Antonio, TX to Chicago, IL which require at least one change with Greyhound, VIA Metropolitan Transit. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Antonio, TX to Chicago, IL, you can count on Greyhound, VIA Metropolitan Transit for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between San Antonio, TX and Chicago, IL and compare the amenities they offer before buying a bus ticket.
A trip to Chicago, IL from San Antonio, TX is worth doing but not as a day trip with a journey time of 26h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Antonio, TX to Chicago, IL is October.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Chicago, IL including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Chicago, IL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Antonio, TX to Chicago, IL for bus company Greyhound.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
Whether you can cancel your bus ticket from San Antonio, TX to Chicago, IL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Chicago, IL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Chicago, IL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Antonio, TX to Chicago, IL.
You can reserve your seat on the bus from San Antonio, TX to Chicago, IL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Antonio, TX to Chicago, IL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Antonio, TX to Chicago, IL with the following bus company: Greyhound.
Since neither San Antonio, TX nor Chicago, IL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from San Antonio, TX to Chicago, IL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Antonio, TX to Chicago, IL
San Antonio
Chicago
The major bus station for departures in San Antonio is San Antonio, N St Mary's St (Greyhound). Find all the information you need to know about services, amenities and connections at San Antonio, N St Mary's St (Greyhound) for your trip from San Antonio to Chicago.
San Antonio, N St Mary's St (Greyhound)
information
San Antonio, Avenue A / Pearl Pkwy
information
The major bus station for arrivals in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip to Chicago from San Antonio.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and San Antonio, TX
Most popular bus connections to Chicago, IL
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