St. Louis, MO to Chicago, IL train with Amtrak

Tue, Nov 18
+ Add return
Amtrak
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Deutsche Bahn
Italo
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Amtrak
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1,000+ travel companies
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The cheapest and fastest trains from St. Louis, MO to Chicago, IL

Showing times and prices for Nov 18

Cheapest price

$44

Average price

$66

Fastest journey

4 h 55 m

Average duration

5 h 8 m

Trains per day

6

Distance

419 km

Cheap tickets

The best way to find a cheap train ticket from St. Louis, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Chicago, IL will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $44.

Fast trains

Of the 6 trains that leave St. Louis, MO for Chicago, IL on Tue, Nov 18, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Nov 18 the direct trains cover the 419 km distance in an average of 5 h 8 m but if you time it right, some trains will get you there in just 4 h 55 m .

On Tue, Nov 18 the slowest trains will take 5 h 34 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Amtrak318 Lincoln Service Missouri River Runner
02:55PM5h05
St. Louis Station, St. Louis, MO
08:00PMChicago Union Station, Chicago, IL
$441One-way
0 transfers
Amtrak300 Lincoln Service
04:30AM4h55
St. Louis Station, St. Louis, MO
09:25AMChicago Union Station, Chicago, IL
$441One-way
0 transfers
Amtrak306 Lincoln Service
05:40PM5h03
St. Louis Station, St. Louis, MO
10:43PMChicago Union Station, Chicago, IL
$441One-way
0 transfers
Amtrak302 Lincoln Service
06:35AM5h05
St. Louis Station, St. Louis, MO
11:40AMChicago Union Station, Chicago, IL
$441One-way
0 transfers
Amtrak22 Texas Eagle
08:10AM5h34
St. Louis Station, St. Louis, MO
01:44PMChicago Union Station, Chicago, IL
$641One-way
0 transfers

Travel Information

Compare train, bus, and flight for St. Louis, MO to Chicago, IL

Omio recommends booking the train as it is the most popular option from St. Louis, MO to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a flight which can get you there in 1h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €28, and a flight costs an average of €253.

Distance: 260 miles (419 km)

Compare train with

Most popular
Train
Bus
Flight

€45

Average price

€45

Average price

Cheapest

€316

Average price

5h 40m

Average total duration

5h 10m

Onboard

+

30m

Additional time*

6h 50m

Average total duration

6h 20m

Onboard

+

30m

Additional time*

4h 21m

Average total duration

Fastest

1h 21m

Onboard

+

3h 0m

Additional time*

0.1 - 0.4kg

CO2 emissions

Lowest

0.4 - 1.0kg

CO2 emissions

1.3 - 2.5kg

CO2 emissions

Amtrak

Most popular train company

Greyhound

Most popular bus company

United

Most popular airline

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

St. Louis, MO to Chicago, IL train times

The table below shows live departures for St. Louis, MO to Chicago, IL trains for tomorrow, Tuesday, November 18. You can also manually refresh the results below to see updated train journeys.

Last updated at 11:44 PM
ProviderDepartsDurationArrivesTransfers
Tickets
amtrak300 Lincoln Service10:30 AM St. Louis Station, St. Louis, MO
4h55
3:25 PM Chicago Union Station, Chicago, IL0 transfersDirect
amtrak302 Lincoln Service12:35 PM St. Louis Station, St. Louis, MO
5h05
5:40 PM Chicago Union Station, Chicago, IL0 transfersDirect
amtrak22 Texas Eagle2:10 PM St. Louis Station, St. Louis, MO
5h34
7:44 PM Chicago Union Station, Chicago, IL0 transfersDirect
amtrak318 Lincoln Service Missouri River Runner8:55 PM St. Louis Station, St. Louis, MO
5h05
2:00 AM Chicago Union Station, Chicago, IL0 transfersDirect
amtrak306 Lincoln Service11:40 PM St. Louis Station, St. Louis, MO
5h03
4:43 AM Chicago Union Station, Chicago, IL0 transfersDirect

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Chicago, IL by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Nov 18
Wed
Nov 19
Thu
Nov 20
Fri
Nov 21
Sat
Nov 22
Sun
Nov 23
Mon
Nov 24

How far in advance should I book train tickets from St. Louis, MO to Chicago, IL?

The best time to book your train from St. Louis, MO to Chicago, IL is 91 days before departure. See how prices for trains change on the St. Louis, MO to Chicago, IL route.
Prices are for one-way tickets for one passenger from St. Louis, MO to Chicago, IL per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from St. Louis, MO to Chicago, IL.

Journey information

Overview: Train from St. Louis, MO to Chicago, IL

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Trains from St. Louis, MO to Chicago, IL run on average 5 times per day, taking around 5h 10m. Cheap train tickets for this journey start at $36 (€29) but you can travel from only $35 (€28) by bus.

There are 5 trains per day. The earliest train runs at 04:30, the last at 23:45. The fastest train covers the 260 miles (419 km) distance in 4h 11m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $35 (€28)
Distance
260 miles (419 km)
Average train duration
5h 10m
Cheapest ticket price
$36 (€29)
Trains per day
5
Direct trains
5
Fastest train
4h 11m
First train
04:30
Last train
23:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $35 (€28)

Train companies: Amtrak from St. Louis, MO to Chicago, IL trainsAmtrak trains will get you between St. Louis, MO and Chicago, IL from $35 (€28). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
4h 11m
Cheapest Price
$35 (€29)
Amtrak frequency
5 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

Traveling by train from St. Louis, MO to Chicago, IL

The train connection between St. Louis, MO and Chicago, IL is a convenient option for travelers looking to explore these vibrant cities. Amtrak provides reliable service on this route, allowing passengers to enjoy comfortable seating and scenic views along the way. With multiple departures daily, it's easy to find a schedule that fits your travel plans while experiencing the ease of rail transportation in the Midwest.

Train Connection: St. Louis to Chicago

Traveling from St. Louis, MO to Chicago, IL takes approximately 4 hours and 55 minutes on a direct train service. There are up to 4 connections available each day, making it convenient for travelers looking to explore these vibrant cities without the hassle of transfers. The journey begins at St. Louis Station in Missouri and concludes at Union Station in Illinois.

St. Louis, MO to Chicago, IL

The first daily train journey departs from St. Louis at 9:30 AM, providing an early start for travelers heading to the Windy City. The last departure of the day is scheduled for 11:40 PM, allowing late-night arrivals in Chicago for those who prefer a later travel option.

Train Tickets Price for St. Louis, MO to Chicago, IL

The cheapest ticket price for the train connection between St. Louis and Chicago is $27 (24.3€). The average ticket price tends to be around $43 (38.7€), making it a convenient option for travelers looking to explore these vibrant cities in the Midwest.

Exploring Chicago's Iconic Landmarks

Welcome to the Willis Tower, once known as the Sears Tower, which held the title of the tallest building in the world for 25 years after its completion in 1973. This iconic skyscraper not only symbolizes Chicago's architectural innovation but also offers breathtaking views from its Skydeck on the 103rd floor, where you can step out onto glass ledges that extend over a stunning drop. As we explore this landmark, you'll discover how it has become an integral part of Chicago’s skyline and a must-visit destination for both locals and tourists alike.

Next up is Millennium Park, inaugurated in 2004 as a vibrant urban oasis that showcases art and culture at every turn. The park features unique attractions like Anish Kapoor's Cloud Gate—affectionately nicknamed "The Bean"—and Jay Pritzker Pavilion with its striking stainless-steel design by Frank Gehry; these elements make it an essential gathering place for events and concerts throughout summer months. Here at Millennium Park, you’ll experience firsthand how public spaces can foster community engagement while celebrating creativity.

Finally, let’s head to Navy Pier—a historic waterfront treasure originally opened in 1916 as a shipping facility—and now transformed into one of Chicago's top tourist destinations filled with entertainment options galore! Stretching over six city blocks along Lake Michigan, Navy Pier boasts thrilling rides like the Centennial Wheel alongside charming gardens and cultural venues such as theaters showcasing local talent. With so much to see and do here—from dining experiences to boat tours—you'll understand why this lively pier continues to attract millions each year!

FAQs: Trains from St. Louis, MO to Chicago, IL

Find answers to the most common questions about traveling from St. Louis, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
To fully experience Chicago, IL, plan for at least 3-4 days to visit key attractions such as Millennium Park, The Art Institute of Chicago, Navy Pier, and explore diverse neighborhoods.
A day trip from St. Louis, MO to Chicago, IL is not feasible as the journey takes 4h 11m, which exceeds the 120-minute limit. The distance is 260 miles (419 km), and there are 5 train trips per day.
The distance by train from St. Louis, MO to Chicago, IL is 260 miles (419 km).
In Chicago, IL, you can explore the Museum of Science and Industry and its interactive exhibits, enjoy the vibrant neighborhoods like Wicker Park and Lincoln Park, take a river cruise to view iconic architecture, and attend a live performance at the historic Chicago Theatre. Visit Lincoln Park Zoo for a free and enjoyable day. For sights, don't miss Millennium Park with its modern art, the renowned Art Institute of Chicago, the entertainment hub of Navy Pier, panoramic views from Willis Tower Skydeck, and the fascinating exhibits at the Field Museum.
The train from St. Louis, MO to Chicago, IL takes 4h 11m and runs 5 per day.
The train journey from St. Louis, MO to Chicago, IL offers a mix of urban and rural scenery. Passengers can enjoy views of the Mississippi River, sprawling farmlands, small towns, and glimpses of the Illinois countryside, making it a pleasant and moderately scenic ride.
The train station in St. Louis, MO that goes to Chicago, IL is St. Louis Station, St. Louis, MO, which connects to Chicago Union Station, Chicago, IL.
The last train from St. Louis, MO to Chicago, IL leaves at 11:45 PM.
Train ticket prices from St. Louis, MO to Chicago, IL can vary. The cheapest ticket starts at $36 (€29), while the average price is around $56 (€45).
Unfortunately, there is no night train available from St. Louis, MO to Chicago, IL.
The cheapest way to get from St. Louis, MO to Chicago, IL is by bus, with a cost of around $35 (€28).
The first train from St. Louis, MO to Chicago, IL leaves at 4:30 AM.
Yes, you can take the train from St. Louis, MO to Chicago, IL.
Yes, there is a direct train from St. Louis, MO to Chicago, IL. This service operates 5 times per day, provided by Amtrak.
There is no high speed train available from St. Louis, MO to Chicago, IL.

popular train stations

Popular train stations from St. Louis, MO to Chicago, IL

St. Louis
Chicago
The major train station for departures in St. Louis is St. Louis Station. Find all the information you need to know about services, amenities and connections at St. Louis Station for your trip from St. Louis to Chicago.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Car RentalCar Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 5:30 AM - 10:00 PM Monday - Sunday
platformCount
Number of platforms
4
Wifi
Wifi
  • Free
Parking
Parking
  • Parking is available on-site with both short-term and long-term options.
Dining
Dining
  • Landry's Seafood House
  • The Station Grille
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Ramps, restrooms.
WC
WC
  • $1
Hotel
Hotel
  • St. Louis Union Station Hotel, Curio Collection by Hilton
  • Courtyard St. Louis Downtown West
  • Drury Inn St. Louis at Union Station
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Car Rental
Car Rental
  • Avis
  • Enterprise
  • Hertz
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
  • Hall 2: MetroLink connections
Public transit options for St. Louis Station
  • MetroLink: Red Line, Blue Line
  • Bus: Several lines available including 40, 94, 97

Most popular trains to and from Chicago, IL and St. Louis, MO

HomeTrainsTrains in USATrain Times to Chicago, ILSt. Louis, MO to Chicago, IL train

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