How to travel from St. Louis, MO to Chicago

Travel options
from St. Louis, MO to Chicago

You can get from St. Louis, MO to Chicago by train, bus or flight.

Our recommendation
train

To get from St. Louis, MO to Chicago on Nov 27 we recommend taking a train because it’s the best combination of price and speed.

05:40PMSt. Louis Station5h25 11:05PMUnion Station
0 transfers
721One-way
Cheapest
05:40PMSt. Louis Station5h25 11:05PMUnion Station
0 transfers
721One-way
Other options
06:30PMSt. Louis Lambert International Airport, MO1h31 08:01PMO'Hare International Airport, IL
0 transfers
2421One-way
10:17AMSt. Louis Lambert International Airport, MO1h17 11:34AMO'Hare International Airport, IL
0 transfers
2421One-way
08:15AMSt. Louis Lambert International Airport, MO1h35 09:50AMO'Hare International Airport, IL
0 transfers
2421One-way

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Travel Information from St. Louis, MO to Chicago

distanceDistance259 miles (418 km)
modeAvailable travel modesBus, ferry, flight or train
priceTicket price range$43 - $211
cheapestCheapest modeTrain • $43 (€40) • 4 h 25 min
fastestFastest modeFlight • $211 (€199) • 1 h 15 min
carriersPopular travel companiesAmerican Airlines or Amtrak

Take a bus, ferry, flight or train to travel 259 miles (418 km) to Chicago from St. Louis, MO. If speed is a priority, then a flight is the best option with an average duration of 1 h 15 min; whereas, if saving money is more important, then a train is the best option with prices starting as low as $43 (€40). The most popular travel companies which serve this journey are American Airlines or Amtrak among others. Travelers can even take a direct train from St. Louis, MO to Chicago.

Travel Tips: Travel from St. Louis, MO to Chicago

Travel Tips: Travel to Chicago easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Chicago.
FAQs

There are 4 ways to travel to Chicago from St. Louis, MO including taking a bus, ferry, flight or train.

The cheapest way to go to Chicago from St. Louis, MO is by taking a train, which costs on average $43 (€40).

This is compared to other ways of getting to Chicago:

A train is generally $14 (€13) less than a bus for the same trip. Taking a bus costs on average $56 (€53) from St. Louis, MO to Chicago.

Taking a train is usually $168 (€159) less than taking a flight to Chicago, which costs on average $211 (€199) for the same trip.

The fastest way from St. Louis, MO to Chicago is by flight with an average journey time of 1 h 15 min.

There are alternative travel options to Chicago that can usually take longer:

In comparison, going by bus can take 6 h 15 min   on average.

In comparison, getting to Chicago by train can take on average 4 h 25 min.

Chicago is approximately 259 miles (418 km) away from St. Louis, MO.

The average frequency per day from St. Louis, MO to Chicago is:

  • 1 bus per day.
  • 4 trains a day.

However, we recommend checking specific travel dates for your journey from St. Louis, MO to Chicago as scheduled services by bus, ferry, flight or train can vary by season or day of the week.

These are the most popular departure and arrival points from St. Louis, MO to Chicago:

    If finding a good deal is your main consideration for your trip from St. Louis, MO to Chicago, then we'll help you find the best value travel companies for you:

    • Travel with American Airlines to go to Chicago by plane. For a good deal on tickets, you can find American Airlines St. Louis, MO to Chicago tickets on Omio for $211 (€199).
    • Amtrak can take you to Chicago by train. If searching for a good deal on trains, you can find tickets for Amtrak from St. Louis, MO to Chicago for $43 (€40).

    Yes, there are direct services available from St. Louis, MO to Chicago with the following travel companies:

    • You can take a direct train with Amtrak with 4 direct trains per day.

    Direct services tend to save you time and add more convenience in getting you to Chicago as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets between St. Louis, MO and Chicago.

    Looking to extend your trip from St. Louis, MO to Chicago? Many Omio customers who go from St. Louis, MO to Chicago usually extend their vacation to explore other popular destinations like New York City, London or Paris. If you're looking to explore New York City, London or Paris from Chicago, let Omio find you the best connections available at an affordable price.

    When planning your trip from St. Louis, MO to Chicago, it’s good to keep in mind what tickets to book and their prices in the next 7 days:

    • Bus tickets are costing on average $56 (€53) one way.
    • Plane tickets cost $211 (€199) one way on average.
    • Train tickets cost on average $43 (€40) one way.

    However, we recommend buying tickets from St. Louis, MO to Chicago online a few months in advance to get the best deals and save money on your upcoming journey.

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

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