4.9
4.6
Travel Information
Compare train, bus, and flight for St. Louis, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $30. For those with little time consider booking a flight which can get you there in 1h 23m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of $30, and a flight costs an average of $106.
Distance: 260 miles (419 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$59 Average price Cheapest | $68 Average price | $408 Average price | $61 Average price (fuel + tolls) |
6h 10m Average total duration 5h 40m Onboard + 30m Additional time* | 6h 29m Average total duration 5h 59m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 4h 21m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.3 - 2.5kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to Chicago, IL:
A train is $9 (€7) less than a bus for this route with tickets for a bus from St. Louis, MO to Chicago, IL costing on average $68 (€55).
A train is $349 (€282) less than a flight for this route with tickets for a flight from St. Louis, MO to Chicago, IL costing on average $408 (€329).
Other travel options to Chicago, IL take longer:
Train takes on average 5h 40m.
Bus takes on average 5h 59m.
Travel optionsfrom St. Louis, MO to Chicago, IL
How to get from St. Louis, MO to Chicago, IL by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Chicago, IL is by taking a train because it’s the best combination of price and speed.
- 306 Lincoln Service5:40 PM5h03St. Louis Station, St. Louis, MO10:43 PMChicago Union Station, Chicago, IL$561One-way0 transfers
Cheapest
- 306 Lincoln Service5:40 PM5h03St. Louis Station, St. Louis, MO10:43 PMChicago Union Station, Chicago, IL$561One-way0 transfers
Fastest
AA38152:36 PM1h29St. Louis Lambert International Airport4:05 PMO'Hare International Airport$4081One-way0 transfers
Other options
- 302 Lincoln Service6:35 AM5h05St. Louis Station, St. Louis, MO11:40 AMChicago Union Station, Chicago, IL$661One-way0 transfers
- 300 Lincoln Service4:30 AM4h55St. Louis Station, St. Louis, MO9:25 AMChicago Union Station, Chicago, IL$791One-way0 transfers
- 318 Lincoln Service Missouri River Runner2:55 PM5h05St. Louis Station, St. Louis, MO8:00 PMChicago Union Station, Chicago, IL$791One-way0 transfers
FlixBus4:00 PM6h05St. Louis, S 15th St (Civic center)10:05 PMChicago, Greyhound Bus Station$661One-way0 transfers- FlixBus11:30 PM6h15St. Louis, S 15th St (Civic center)5:45 AMChicago, Greyhound Bus Station$661One-way0 transfers
- FlixBus10:00 AM6h05St. Louis, S 15th St (Civic center)4:05 PMChicago, Greyhound Bus Station$741One-way0 transfers
AA19266:00 AM1h29St. Louis Lambert International Airport7:29 AMO'Hare International Airport$4081One-way0 transfers- AA23247:00 AM1h29St. Louis Lambert International Airport8:29 AMO'Hare International Airport$4081One-way0 transfers
- UA10086:00 AM1h30St. Louis Lambert International Airport7:30 AMO'Hare International Airport$4081One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from St. Louis, MO to Chicago, IL
Travel to Chicago, IL easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Chicago, IL.
This is compared to other travel options from St. Louis, MO to Chicago, IL:
A train is $9 (€7) less than a bus for this route with tickets for a bus from St. Louis, MO to Chicago, IL costing on average $68 (€55).
A train is $349 (€282) less than a flight for this route with tickets for a flight from St. Louis, MO to Chicago, IL costing on average $408 (€329).
Other travel options to Chicago, IL take longer:
Train takes on average 5h 40m.
Bus takes on average 5h 59m.
- Around 27 flights per day.
- Around 6 trains per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between St. Louis, MO and Chicago, IL as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from St. Louis Lambert International Airport and arrive in O'Hare International Airport.
- Trains mostly depart from St. Louis Station, St. Louis, MO and arrive in Chicago Union Station, Chicago, IL.
- Buses mostly depart from St. Louis, S 15th St (Civic center) and arrive in Chicago, Greyhound Bus Station.
- Travel with Greyhound, FlixBus to go to Chicago, IL by bus.
- Travel with United, Republic Airlines, American Airlines to go to Chicago, IL by flight.
- Travel with Amtrak to go to Chicago, IL by train.
- 2 direct buses per day with Greyhound, FlixBus.
- 8 direct flights per day with United, Republic Airlines, American Airlines.
- 5 direct trains per day with Amtrak.
Travelling from St. Louis, MO to Chicago, IL: related information
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