Travel options
from St. Louis, MO to Chicago

You can get from St. Louis, MO to Chicago by train, bus or flight.

Our recommendation

To get from St. Louis, MO to Chicago on Jan 18 we recommend taking a train because it’s the best combination of price and speed.

03:00PMSt. Louis Station5h25 08:25PMUnion Station
0 changes
$351One-way
Cheapest
03:00PMSt. Louis Station5h25 08:25PMUnion Station
0 changes
$351One-way
Other options
04:30AMSt. Louis Station5h09 09:39AMUnion Station
0 changes
$351One-way
07:55AMSt. Louis Station5h49 01:44PMUnion Station
0 changes
$351One-way
05:40PMSt. Louis Station5h25 11:05PMUnion Station
0 changes
$351One-way

Find all the dates and times for this journey by train, bus, and flight, .

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Travel Information to Chicago from St. Louis, MO

distanceDistance259 miles (418 km)
modeAvailable travel modesFlight, bus or train
priceTicket price range$28 - $112
cheapestCheapest modeTrain • $28 (€23) • 5 h 9 min
fastestFastest modeFlight • $112 (€92) • 1 h 23 min
carriersPopular travel companiesgojet airlines, Greyhound or Amtrak

Travel 259 miles (418 km) by flight, bus or train to Chicago from St. Louis, MO. If speed is a priority, then a flight is the best option with an average duration of 1 h 23 min; whereas, if saving money is more important, then a train is the best option with prices starting as low as $28 (€23). The most popular travel companies which serve this route are gojet airlines, Greyhound or Amtrak among others. Travelers can even take a direct from St. Louis, MO to Chicago.

Travel Tips: Travel from St. Louis, MO to Chicago

Travel to Chicago easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Chicago.
FAQs

How do I get from St. Louis, MO to Chicago?

There are 3 travel options from St. Louis, MO to Chicago: flight, bus or train.

How do I get from St. Louis, MO to Chicago the cheapest way?

The cheapest way to go to Chicago from St. Louis, MO is by taking a train, which costs on average $28 (€23).

This is compared to other ways of getting to Chicago:

Taking a train is about $83 (€69) less than taking a flight, which costs on average $112 (€92) for this journey.

Taking a train is usually $14 (€11) less than taking a bus to Chicago, which costs on average $42 (€35) for the same trip.

What is the fastest way to travel between St. Louis, MO and Chicago?

The quickest way to travel from St. Louis, MO to Chicago is by flight, which takes on average 1 h 23 min   compared to other travel options that may take you longer to get to your destination:

In comparison, traveling by bus can take you on average 6 h 15 min.

In comparison, going by train can take 5 h 9 min   on average.

What is the distance from St. Louis, MO to Chicago?

You should expect to travel around 259 miles (418 km) between St. Louis, MO and Chicago.

When traveling between St. Louis, MO and Chicago, where do I depart from St. Louis, MO and where do I arrive in Chicago?

These are the most popular departure and arrival points when traveling from St. Louis, MO to Chicago:

    Which travel operators can get me to Chicago from St. Louis, MO?

    Omio works with many trusted partners that can help you travel the best way from St. Louis, MO to Chicago:

    • You can go to Chicago from St. Louis, MO by plane with gojet airlines. You'll see cheap plane tickets for $112 (€92) with gojet airlines from St. Louis, MO to Chicago on Omio.
    • You can go to Chicago from St. Louis, MO by bus with Greyhound. You'll see cheap bus tickets for $42 (€35) with Greyhound from St. Louis, MO to Chicago on Omio.
    • You can travel to Chicago from St. Louis, MO by train with Amtrak. You can find cheap tickets on Omio for $28 (€23) with Amtrak from St. Louis, MO to Chicago.

    What is another destination I should add to my tour from St. Louis, MO to Chicago?

    Your trip from St. Louis, MO to Chicago doesn't have to end in Chicago. Many of our customers like to extend their vacation to explore other popular destinations like New York City, London or Paris. If you’d like to add New York City, London or Paris to your St. Louis, MO to Chicago tour, check Omio for the best and cheapest ways to travel to any of these top destinations from Chicago today!

    How far in advance should I buy tickets to Chicago from St. Louis, MO online to get the best deals?

    Before traveling from St. Louis, MO to Chicago, it’s good to know what ticket you can purchase and how much it will cost in the next 7 days:

    • A plane ticket is costing on average $112 (€92) one way for this trip.
    • A bus ticket for this trip costs on average $42 (€35) one way.
    • A train ticket costs $28 (€23) one way on average for this route.

    But we recommend booking St. Louis, MO to Chicago tickets online a few months before your planned travel date to score the best deals and save money on your trip.