San Diego, CA to Chicago, IL bus with Greyhound

Sat, Feb 21
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1,000+ travel companies
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The cheapest and fastest buses from San Diego, CA to Chicago, IL

Showing times and prices for Feb 24

Cheapest price

$147

Average price

$358

Fastest journey

2 d 1 h 15 m

Average duration

2 d 6 h 45 m

Buses per day

5

Distance

2784 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to Chicago, IL will cost around $358 if you buy it on the day, but the cheapest tickets can be found for only $147.

Fast buses

Of the 5 buses that leave San Diego, CA for Chicago, IL on Tue, Feb 24, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Feb 24 the direct buses cover the 2784 km distance in an average of 2 d 6 h 45 m but if you time it right, some buses will get you there in just 2 d 1 h 15 m .

On Tue, Feb 24 the slowest buses will take 2 d 16 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
02:15AM55h25
San Diego, CA
09:40AMChicago, IL
$1471One-way
0 transfers
Greyhound
08:40PM49h50
San Diego, CA
10:30PMChicago, IL
$2051One-way
0 transfers
Greyhound
09:45PM64h05
San Diego, CA
01:50PMChicago, IL
$3881One-way
0 transfers
Greyhound
03:00AM55h10
San Diego, CA
10:10AMChicago, IL
$5121One-way
0 transfers
Greyhound
09:15PM49h15
San Diego, CA
10:30PMChicago, IL
$5391One-way
0 transfers

Travel Information

Compare train, bus, and flight for San Diego, CA to Chicago, IL

Omio recommends booking the train as it is the most popular option from San Diego, CA to Chicago, IL among Omio's users. If you are prioritising price take the flight with prices starting from €69. For those with little time consider booking a flight which can get you there in 4h 33m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.8 - 2.5kg. The ticket price range depends on the travel mode: a flight costs an average of €69, and a train costs an average of €161.

Distance: 1729 miles (2784 km)

Compare bus with

Bus
Most popular
Train
Flight

€285

Average price

€475

Average price

€233

Average price

Cheapest

49h 18m

Average total duration

48h 48m

Onboard

+

30m

Additional time*

48h 54m

Average total duration

48h 24m

Onboard

+

30m

Additional time*

7h 33m

Average total duration

Fastest

4h 33m

Onboard

+

3h 0m

Additional time*

2.8 - 7.0kg

CO2 emissions

0.8 - 2.5kg

CO2 emissions

Lowest

8.4 - 16.7kg

CO2 emissions

Greyhound

Most popular bus company

Amtrak

Most popular train company

Spirit Airlines

Most popular airline

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

San Diego, CA to Chicago, IL bus times

The table below shows live departures for San Diego, CA to Chicago, IL buses for today, Sunday, February 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at 6:33 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound2:45 PM San Diego, CA
55h40
10:25 PM Chicago, IL0 transfersDirect
greyhound8:40 PM San Diego, CA
49h50
10:30 PM Chicago, IL0 transfersDirect
greyhound9:15 PM San Diego, CA
50h00
11:15 PM Chicago, IL0 transfersDirect
greyhound11:55 PM San Diego, CA
58h15
10:10 AM Chicago, IL0 transfersDirect
Monday, February 23
greyhound2:15 AM San Diego, CA
55h25
9:40 AM Chicago, IL0 transfersDirect
greyhound3:00 AM San Diego, CA
55h10
10:10 AM Chicago, IL0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Diego, CA to Chicago, IL by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Feb 23
Tue
Feb 24
Wed
Feb 25
Thu
Feb 26
Fri
Feb 27
Sat
Feb 28
Sun
Mar 01

Why should you book San Diego, CA to Chicago, IL buses with Omio?

Greyhound operates all buses services from San Diego, CA to Chicago, IL.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Chicago, IL.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to Chicago, IL.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to Chicago, IL.

Journey information

Overview: Bus from San Diego, CA to Chicago, IL

USAUSA
USAUSA
Icon of bus

Buses from San Diego, CA to Chicago, IL run on average 12 times per day, taking around 48h 48m. Cheap bus tickets for this journey start at $147 (€117) but you can travel from only $86 (€69) by flight.

The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 1729 miles (2784 km) distance in 48h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $86 (€69)
Distance
1729 miles (2784 km)
Average bus duration
48h 48m
Cheapest ticket price
$147 (€117)
Buses per day
12
Fastest bus
48h 35m
First bus
00:15
Last bus
23:10
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $86 (€69)

Bus providers: Greyhound from San Diego, CA to Chicago, ILYou can travel by bus between San Diego, CA to Chicago, IL with Greyhound for as low as $86 (€69). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
48h 35m
Cheapest Price
$147 (€117)
Greyhound frequency
11 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from San Diego, CA to Chicago, IL

Find answers to the most common questions about traveling from San Diego, CA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to Chicago, IL can start from as little as $147 (€117) when you book in advance. The average bus ticket price for San Diego, CA to Chicago, IL is $358 (€285) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Chicago, IL is 48h 35m to travel the 1729 miles (2784 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Chicago, IL leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Chicago, IL leaves at 11:10 PM.
There are 12 buses a day from San Diego, CA to Chicago, IL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Chicago, IL, you can count on Greyhound for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between San Diego, CA and Chicago, IL and compare the amenities they offer before buying a bus ticket.
A trip to Chicago, IL from San Diego, CA is worth doing but not as a day trip with a journey time of 48h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Chicago, IL is September.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Chicago, IL including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Chicago, IL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Chicago, IL for bus company Greyhound.
Some of the most interesting sights to explore in Chicago, IL are:
  • Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
  • Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
  • Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
  • Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
  • Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
  • Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
  • Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
  • Take a river cruise to see the city's iconic architecture from a different perspective
  • Attend a live performance at the historic Chicago Theatre
  • Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
Whether you can cancel your bus ticket from San Diego, CA to Chicago, IL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Chicago, IL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Chicago, IL:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Chicago, IL.
You can reserve your seat on the bus from San Diego, CA to Chicago, IL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Chicago, IL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Chicago, IL with the following bus company: Greyhound.

popular bus stations

Popular bus stations from San Diego, CA to Chicago, IL

San Diego
Chicago
The major bus station for departures in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip from San Diego to Chicago.
San Diego, Congress Street (Old Town Park)
information
San Diego, San Ysidro Transit Center
information
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information
HomeBusesBuses in USABus tickets to Chicago, ILSan Diego, CA to Chicago, IL bus

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