Pisa to Brussels bus with FlixBus

Fri, Mar 06
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Costa Verde
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Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Pisa to Brussels

Showing times and prices for Mar 06

Cheapest price

$85

Average price

$110

Fastest journey

1 d 1 h 10 m

Average duration

1 d 2 h 25 m

Buses per day

4

Distance

914 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Brussels will cost around $110 if you buy it on the day, but the cheapest tickets can be found for only $85.

Fast buses

Of the 4 buses that leave Pisa for Brussels on Fri, Mar 06, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Mar 06 the direct buses cover the 914 km distance in an average of 1 d 2 h 25 m but if you time it right, some buses will get you there in just 1 d 1 h 10 m .

On Fri, Mar 06 the slowest buses will take 1 d 3 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
03:45PM25h10
Pisa
04:55PMBrussels
$851One-way
0 transfers
FlixBus
08:40AM27h05
Pisa
11:45AMBrussels
$971One-way
0 transfers
FlixBus
10:30PM27h35
Pisa
02:05AMBrussels
$1231One-way
0 transfers
FlixBus
05:25AM25h50
Pisa
07:15AMBrussels
$1351One-way
0 transfers

Travel Information

Compare train, bus, and flight for Pisa to Brussels

Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $74. For those with little time consider booking a flight which can get you there in 2h 30m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $74, and a train costs an average of $364.

Distance: 567 miles (914 km)

Compare bus with

Bus
Most popular
Flight
Train

$125

Average price

Cheapest

$127

Average price

$364

Average price

21h 28m

Average total duration

20h 58m

Onboard

+

30m

Additional time*

5h 30m

Average total duration

Fastest

2h 30m

Onboard

+

3h 0m

Additional time*

21h 8m

Average total duration

20h 38m

Onboard

+

30m

Additional time*

0.9 - 2.3kg

CO2 emissions

Lowest

2.7 - 5.5kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Pisa to Brussels bus times

The table below shows live departures for Pisa to Brussels buses for today, Thursday, March 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 7:31 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus10:45 PM Pisa
32h30
7:15 AM Brussels0 transfersDirect
Friday, March 6
meinfernbus_flixbus5:25 AM Pisa
25h50
7:15 AM Brussels0 transfersDirect
meinfernbus_flixbus8:40 AM Pisa
27h05
11:45 AM Brussels0 transfersDirect
meinfernbus_flixbus3:45 PM Pisa
25h10
4:55 PM Brussels0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Brussels by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Mar 06
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Mar 26

Why should you book Pisa to Brussels buses with Omio?

FlixBus operates all buses services from Pisa to Brussels.
Omio is an official ticket reseller for all your travel options from Pisa to Brussels.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Brussels.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Brussels.

Journey information

Overview: Bus from Pisa to Brussels

ItalyItaly
BelgiumBelgium
Icon of bus

Buses from Pisa to Brussels run on average 5 times per day, taking around 20h 58m. Cheap bus tickets for this journey start at $74 (€60) but you can travel from only $21 (€17) by flight.

The earliest bus runs at 01:30, the last at 23:45. The fastest bus covers the 567 miles (914 km) distance in 22h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Distance
567 miles (914 km)
Average bus duration
20h 58m
Cheapest ticket price
$74 (€60)
Buses per day
5
Fastest bus
22h 35m
First bus
01:30
Last bus
23:45
Cheapest month
Apr
Cheapest day
Tue
High season
Oct - Dec
Low season
Jan - Mar
Busiest day
Wed
Least busy day
Fri
Best day to book ahead
42 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)

Bus providers: FlixBus from Pisa to BrusselsYou can travel by bus between Pisa to Brussels with FlixBus for as low as $21 (€17). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
22h 35m
Cheapest Price
$74 (€60)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Pisa to Brussels

Find answers to the most common questions about traveling from Pisa to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Brussels can start from as little as $74 (€60) when you book in advance. The average bus ticket price for Pisa to Brussels is $125 (€101) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Brussels is 22h 35m to travel the 567 miles (914 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Brussels leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Brussels leaves at 11:45 PM.
There are 5 buses a day from Pisa to Brussels which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Brussels, you can count on FlixBus for the best way to get you to Brussels. You can also check all possible bus companies who offer a service between Pisa and Brussels and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Aeroporto Parcheggio Aurelia, Lucca, Viale Regina Margherita / Via Montanara . When arriving in Brussels , you can end your journey in bus stations like Brussels, Brussels South (Gare du Midi), Bruxelles, Gare du Nord, Brussels, Gare Du Midi, Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord) .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 away from the city centre, and they get off the bus at Brussels, Brussels South (Gare du Midi), located 2 away from the city centre.
A trip to Brussels from Pisa is worth doing but not as a day trip with a journey time of 22h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Brussels is April.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Brussels including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Brussels:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Brussels for bus company FlixBus.
Some of the most interesting sights to explore in Brussels are:
  • Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
  • Atomium, an iconic structure and museum offering panoramic views of the city
  • Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
  • Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
  • Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
  • Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
  • Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
  • Sample Belgian chocolates at one of the city's renowned chocolatiers
  • Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
  • Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Whether you can cancel your bus ticket from Pisa to Brussels depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Brussels:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Brussels:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Brussels. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Brussels with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Brussels with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Brussels with the following bus company: FlixBus.

popular bus stations

Popular bus stations from Pisa to Brussels

Pisa
Brussels
The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Brussels.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Pisa, Aeroporto Parcheggio Aurelia
information

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