Pisa to Brussels bus with FlixBus

Fri, Dec 05
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Rede Expressos
Itabus
1,000+ travel companies
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The cheapest and fastest buses from Pisa to Brussels

Showing times and prices for Dec 06

Cheapest price

$89

Average price

$98

Fastest journey

1 d

Average duration

1 d 2 h 4 m

Buses per day

5

Distance

914 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Brussels will cost around $98 if you buy it on the day, but the cheapest tickets can be found for only $89.

Fast buses

It's difficult to get from Pisa to Brussels without transferring at least 2 times.

FlixBusFlixBus · FlixBus · FlixBus
01:40PM26h10
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
03:50PMBrussels, Gare Du Midi
$891One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
06:25AM25h50
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
08:15AMBrussels, Brussels South (Gare du Midi)
$891One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
01:40PM24h00
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
01:40PMBrussels, Brussels South (Gare du Midi)
$931One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
07:10AM29h10
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
12:20PMBrussels, Brussels South (Gare du Midi)
$1001One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
04:45PM25h10
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
05:55PMBrussels, Brussels South (Gare du Midi)
$1191One-way
2 transfers

Travel Information

Compare train, bus, and flight for Pisa to Brussels

Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from €25. For those with little time consider booking a flight which can get you there in 2h 33m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of €25, and a train costs an average of €300.

Distance: 567 miles (914 km)

Compare bus with

Bus
Most popular
Flight
Train

€117

Average price

€94

Average price

Cheapest

€300

Average price

21h 28m

Average total duration

20h 58m

Onboard

+

30m

Additional time*

5h 33m

Average total duration

Fastest

2h 33m

Onboard

+

3h 0m

Additional time*

21h 8m

Average total duration

20h 38m

Onboard

+

30m

Additional time*

0.9 - 2.3kg

CO2 emissions

Lowest

2.7 - 5.5kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Pisa to Brussels Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
06:25AM
Arrival Time
08:15AM
Duration
25h50
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$89
Operator
FlixBus
Departure Time
07:10AM
Arrival Time
12:20PM
Duration
29h10
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$100
Operator
FlixBus
Departure Time
01:40PM
Arrival Time
03:35PM
Duration
25h55
Departure days
Fri, Sat, Sun
Cheapest price
$89
Operator
FlixBus
Departure Time
04:45PM
Arrival Time
05:55PM
Duration
25h10
Departure days
Fri, Sat, Sun
Cheapest price
$92

Live departures

Pisa to Brussels bus times

The table below shows live departures for Pisa to Brussels buses for today, Friday, December 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 3:59 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus · FlixBus5:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
25h50
7:15 AM Brussels, Brussels South (Gare du Midi)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
29h10
11:20 AM Brussels, Brussels South (Gare du Midi)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus12:40 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
25h55
2:35 PM Brussels, Brussels South (Gare du Midi)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
25h10
4:55 PM Brussels, Brussels South (Gare du Midi)2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Brussels by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Pisa to Brussels

ItalyItaly
BelgiumBelgium
Icon of bus

Buses from Pisa to Brussels run on average 6 times per day, taking around 20h 58m. Cheap bus tickets for this journey start at $57 (€46) but you can travel from only $31 (€25) by flight.

The earliest bus runs at 01:30, the last at 23:45. The fastest bus covers the 567 miles (914 km) distance in 25h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)
Distance
567 miles (914 km)
Average bus duration
20h 58m
Cheapest ticket price
$57 (€46)
Buses per day
6
Fastest bus
25h 10m
First bus
01:30
Last bus
23:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)

Bus providers: FlixBus from Pisa to BrusselsYou can travel by bus between Pisa to Brussels with FlixBus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
25h 10m
Cheapest Price
$69 (€55)
FlixBus frequency
7 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Pisa to Brussels

Find answers to the most common questions about traveling from Pisa to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Brussels can start from as little as $85 (€68) when you book in advance. The average bus ticket price for Pisa to Brussels is $139 (€112); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Pisa to Brussels bus time is 21 h 5 min   covering the 567 mile (914 km) long route, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Pisa to Brussels leaves at 3: 50AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Pisa to Brussels leaves at 10: 30PM.
There are 7 buses a day from Pisa to Brussels which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
For the best Pisa to Brussels bus to buy, you can travel safely and comfortably with FlixBus. However, it's always good to check all possible bus companies with services between Pisa and Brussels to compare what amenities they may offer.
The cheapest month to travel from Pisa to Brussels by bus is December.
You have options as you can travel to Brussels from Pisa 3 different ways: train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Brussels:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Brussels for bus company FlixBus.
Some of the most interesting sights to explore in Brussels are:
  • Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
  • Atomium, an iconic structure and museum offering panoramic views of the city
  • Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
  • Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
  • Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
  • Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
  • Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
  • Sample Belgian chocolates at one of the city's renowned chocolatiers
  • Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
  • Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Pisa to Brussels depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Pisa to Brussels, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Pisa to Brussels.
    Yes, the following luggage options are included when booking a bus ticket from Pisa to Brussels:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Brussels:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Pisa to Brussels. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Pisa to Brussels with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Pisa to Brussels with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Pisa to Brussels with the following bus company: FlixBus.

    popular bus stations

    Popular bus stations from Pisa to Brussels

    Pisa
    Brussels
    The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Brussels.
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    Pisa, Aeroporto Parcheggio Aurelia
    information

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