Travel Information
Compare train, bus, and flight for Pisa to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $75. For those with little time consider booking a flight which can get you there in 2h 30m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $75, and a train costs an average of $369.
Distance: 567 miles (914 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$129 Average price | $126 Average price Cheapest | $369 Average price | $358 Average price (fuel + tolls) |
5h 30m Average total duration Fastest 2h 30m Onboard + 3h 0m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* | 21h 8m Average total duration 20h 38m Onboard + 30m Additional time* | 12h 39m Average total duration (door-to-door) |
2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Brussels:
A bus is $2 (€2) less than a flight for this route with tickets for a flight from Pisa to Brussels costing on average $129 (€103).
A bus is $243 (€194) less than a train for this route with tickets for a train from Pisa to Brussels costing on average $369 (€295).
Other travel options to Brussels take longer:
Train takes on average 20h 38m.
Bus takes on average 20h 58m.
Travel optionsfrom Pisa to Brussels
How to get from Pisa to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brussels is by taking a bus because it’s the best combination of price and speed.
3:45 PM25h10Pisa4:55 PMBrussels$861One-way0 transfers
Cheapest
3:45 PM25h10Pisa4:55 PMBrussels$861One-way0 transfers
Fastest
3:45 PM25h10Pisa4:55 PMBrussels$861One-way0 transfers
Other options
8:40 AM27h05Pisa11:45 AMBrussels$981One-way0 transfers
10:30 PM27h35Pisa2:05 AMBrussels$1241One-way0 transfers
5:25 AM25h50Pisa7:15 AMBrussels$1371One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Pisa to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brussels.

This is compared to other travel options from Pisa to Brussels:
A bus is $2 (€2) less than a flight for this route with tickets for a flight from Pisa to Brussels costing on average $129 (€103).
A bus is $243 (€194) less than a train for this route with tickets for a train from Pisa to Brussels costing on average $369 (€295).
Other travel options to Brussels take longer:
Train takes on average 20h 38m.
Bus takes on average 20h 58m.
- Around 5 flights per day.
- Around 5 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Brussels Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Ryanair, Malta Air, Vueling, Air Dolomiti to go to Brussels by flight.
- Travel with Regionale to go to Brussels by train.
- Travel with FlixBus to go to Brussels by bus.
- 2 direct flights per day with Malta Air.
Travelling from Pisa to Brussels: related information
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