Travel Information
Compare train, bus, and flight for Pisa to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $23. For those with little time consider booking a flight which can get you there in 2h 31m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of $23, and a train costs an average of $280.
Distance: 567 miles (914 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$134 Average price Cheapest | $135 Average price | $372 Average price | $350 Average price (fuel + tolls) |
5h 31m Average total duration Fastest 2h 31m Onboard + 3h 0m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* | 19h 50m Average total duration 19h 20m Onboard + 30m Additional time* | 12h 39m Average total duration (door-to-door) |
2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Brussels:
A flight is $2 less than a bus for this route with tickets for a bus from Pisa to Brussels costing on average $135.
A flight is $239 less than a train for this route with tickets for a train from Pisa to Brussels costing on average $372.
Other travel options to Brussels take longer:
Train takes on average 19h 20m.
Bus takes on average 20h 58m.
Travel optionsfrom Pisa to Brussels
How to get from Pisa to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus6:25 AM25h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:15 AMBrussels, Brussels South (Gare du Midi)$1711One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus6:25 AM25h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:15 AMBrussels, Brussels South (Gare du Midi)$1711One-way2 transfers
Fastest
FR 37469:15 AM1h45Pisa International Airport11:00 AMBrussels South Charleroi Airport$2501One-way0 transfers
Other options
FlixBus · FlixBus · FlixBus4:45 PM25h10Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:55 PMBrussels, Brussels South (Gare du Midi)$1841One-way2 transfers
FlixBus · FlixBus · FlixBus9:40 AM27h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)12:45 PMBrussels, Brussels South (Gare du Midi)$2031One-way2 transfers
FR 37478:50 PM1h45Pisa International Airport10:35 PMBrussels South Charleroi Airport$2501One-way0 transfers
HV5424+
93983:00 PM8h06Pisa International Airport11:06 PMBrussels-Midi$4311One-way1 transfer
BA617 · BA3909:20 PM23h20Pisa International Airport8:40 PMBrussels Airport$4861One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brussels.

This is compared to other travel options from Pisa to Brussels:
A flight is $2 less than a bus for this route with tickets for a bus from Pisa to Brussels costing on average $135.
A flight is $239 less than a train for this route with tickets for a train from Pisa to Brussels costing on average $372.
Other travel options to Brussels take longer:
Train takes on average 19h 20m.
Bus takes on average 20h 58m.
- Around 5 flights per day.
- Around 4 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brussels, Brussels South (Gare du Midi).
- Flights mostly depart from Pisa International Airport and arrive in Brussels Airport.
- Travel with Malta Air, Ryanair, Vueling, Air Dolomiti to go to Brussels by flight.
- Travel with FlixBus to go to Brussels by bus.
- Travel with Regionale to go to Brussels by train.
- 2 direct flights per day with Malta Air, Ryanair.
Travelling from Pisa to Brussels: related information
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