- Must visit
Musical Instruments Museum
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.
Cheapest price
$73
Average price
$113
Fastest journey
12 h 45 m
Average duration
15 h 55 m
Buses per day
7
Distance
698 km
The best way to find a cheap bus ticket from Milan to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Brussels will cost around $113 if you buy it on the day, but the cheapest tickets can be found for only $73.
Of the 7 buses that leave Milan for Brussels on Tue, Jul 07, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jul 07 the direct buses cover the 698 km distance in an average of 15 h 55 m but if you time it right, some buses will get you there in just 12 h 45 m .
On Tue, Jul 07 the slowest buses will take 18 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4739
4743
94742 · 1657
FlixBus · FlixBus
FlixBus · FlixBus
4739
4743
94742 · 1657
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Milan to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a flight which can get you there in 3h 14m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.7kg. The ticket price range depends on the travel mode: a bus costs an average of $33, and a train costs an average of $115.
Distance: 433 miles (698 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$72 Average price Cheapest | $167 Average price | $429 Average price | $265 Average price (fuel + tolls) |
12h 11m Average total duration 11h 41m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 3h 14m Onboard + 3h 0m Additional time* | 10h 23m Average total duration 9h 53m Onboard + 30m Additional time* | 10h 15m Average total duration (door-to-door) |
0.7 - 1.7kg CO2 emissions Lowest | 2.1 - 4.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Brussels:
A bus is $96 (€79) less than a flight for this route with tickets for a flight from Milan to Brussels costing on average $167 (€137).
A bus is $358 (€294) less than a train for this route with tickets for a train from Milan to Brussels costing on average $429 (€353).
Other travel options to Brussels take longer:
Train takes on average 9h 53m.
Bus takes on average 11h 41m.
Tickets start at around $72 (€59) compared to roughly $265 (€217) in fuel and tolls — a saving of about $193 (€159). The journey takes 11h 41m versus 10h 15m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, FlixBus, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 12:35AM | Duration 18h50 | Departure days Wed, Thu | Cheapest price $89 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 03:05AM | Duration 18h35 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 01:40PM | Duration 27h20 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $134 |
Operator BlaBlaCar Bus | Departure Time 03:20PM | Arrival Time 04:55AM | Duration 13h35 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator BlaBlaCar Bus | Departure Time 06:50PM | Arrival Time 12:00PM | Duration 17h10 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $54 |
Operator FlixBus | Departure Time 07:15PM | Arrival Time 12:45PM | Duration 17h30 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator BlaBlaCar Bus | Departure Time 07:55PM | Arrival Time 08:40AM | Duration 12h45 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator BlaBlaCar Bus | Departure Time 08:00PM | Arrival Time 01:30PM | Duration 17h30 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 01:55PM | Duration 17h30 | Departure days Fri, Sat | Cheapest price $108 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 02:40PM | Duration 41h40 | Departure days Mon | Cheapest price $278 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 03:45PM | Duration 17h15 | Departure days Wed, Fri, Sat, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 11:35AM | Duration 12h50 | Departure days Mon | Cheapest price $113 |
Operator BlaBlaCar Bus | Departure Time 11:55PM | Arrival Time 05:30PM | Duration 17h35 | Departure days Wed, Sat, Sun | Cheapest price $51 |
The table below shows live departures for Milan to Brussels buses for tomorrow, Tuesday, July 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:30 AM Milano, Autostazione Lampugnano | 18h35 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 27h20 | 1:40 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 29h30 | 3:50 PM Brussels, Gare Du Midi | 2 transfers | |
4743 | 3:20 PM Milano, Autostazione Lampugnano | 13h35 | 4:55 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
94742 · 1657 | 6:50 PM Milano, Autostazione Lampugnano | 17h10 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 7:15 PM Milano, Autostazione Lampugnano | 17h30 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
4739 | 7:55 PM Milano, Autostazione Lampugnano | 12h45 | 8:40 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Brussels run on average 8 times per day, taking around 11h 41m. Cheap bus tickets for this journey start at $33 (€27) but you can travel from only $24 (€20) by flight.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 433 miles (698 km) distance in 12h 45m.
Distance 433 miles (698 km) |
Average bus duration 11h 41m |
Cheapest ticket price $33 (€27) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 12h 45m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Mon |
Best time to book 84 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.
Leading museum dedicated to René Magritte, presenting a large collection of surrealist works in the Royal Museums complex.
Flagship fine arts museums covering Flemish masters, Belgian art, and major temporary exhibitions in central Brussels.
Elegant 19th-century covered arcade lined with historic shops and cafes, popular for architecture, strolling, and photos.
Terraced garden and viewpoint with one of the most recognizable panoramas in central Brussels.
Stylish square known for antiques, architecture, and an upscale yet distinctly Brussels atmosphere.
Mussels steamed with white wine, celery, and herbs, served with fries. It is one of Belgium’s most iconic comfort dishes and a staple in Brussels brasseries.
A traditional Belgian beef and onion stew slowly cooked with dark Belgian beer, often slightly sweet-sour and served with fries or bread.
A rustic Brussels side dish of mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, commonly served with sausage or meat dishes.
One of Brussels’ most famous fine dining institutions, celebrated for refined Belgian-French cuisine and elegant historic interiors.
Popular traditional restaurant known for generous Belgian comfort food, beer-based dishes, and an informal, bustling atmosphere.
Historic, long-running brasserie best known for moules-frites and classic Belgian dishes in a lively central setting.
Brussels is pricier than many Belgian cities. Hotels and dining add up, but transit and casual eats are manageable.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for great service is appreciated. Round up taxi fares; small tips are optional at cafes and bars.
Official public transport app
Brussels South (Gare du Midi), Brussels -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Milan to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Milan to Brussels buses use the Milano, Autostazione Lampugnano to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussels, Gare Du Midi. Use this guide to compare Milan and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
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