Pisa PSA to Brussels BRU flight with Ryanair

Sun, Dec 21
+ Add return
Ryanair
KM Malta Airlines
Air Dolomiti
Vueling Airlines
easyJet
1,000+ travel companies
Ryanair
KM Malta Airlines
Air Dolomiti
Vueling Airlines
easyJet
1,000+ travel companies
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Journey information

Overview: Pisa to Brussels flight

ItalyItaly
BelgiumBelgium
Icon of flight

Flights from Pisa to Brussels depart on average 6 times per day, taking around 2h 33m. Cheap flight tickets for this journey start at $31 (€25) if you book in advance.

There are 2 flights per day. The earliest flight runs at 00:32, the last at 22:40. The fastest flight covers the 567 miles (914 km) distance in 1h 40m. February is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
567 miles (914 km)
Average flight duration
2h 33m
Cheapest ticket price
$31 (€25)
Flights per day
6
Direct flights
2
Fastest flight
1h 40m
Cheapest month to travel
February
First flight
00:32
Last flight
22:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

The cheapest and fastest flights from Pisa to Brussels

Showing times and prices for Dec 21

Cheapest price

$44

Average price

$117

Fastest journey

1 h 40 m

Average duration

1 h 45 m

Flights per day

3

Distance

914 km

Cheap tickets

The best way to find a cheap flight ticket from Pisa to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Brussels will cost around $117 if you buy it on the day, but the cheapest tickets can be found for only $44.

Fast flights

Of the 3 flights that leave Pisa for Brussels onSun, Dec 21, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, Dec 21 the direct flights cover the 914 km distance in an average of 1 h 45 m but if you time it right, some flights will get you there in just 1 h 40 m .

On Sun, Dec 21 the longest flights will take 1 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Ryanair
04:00AM1h50
Pisa
05:50AMBrussels
$441One-way
0 transfers
Ryanair
12:55PM1h45
Pisa
02:40PMBrussels
$1481One-way
0 transfers
Ryanair
06:10PM1h40
Pisa
07:50PMBrussels
$1591One-way
0 transfers

Travel Information

Compare train, bus, and flight for Pisa to Brussels

Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from €25. For those with little time consider booking a flight which can get you there in 2h 33m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of €25, and a train costs an average of €300.

Distance: 567 miles (914 km)

Compare flight with

Most popular
Flight
Bus
Train

€94

Average price

Cheapest

€117

Average price

€300

Average price

5h 33m

Average total duration

Fastest

2h 33m

Onboard

+

3h 0m

Additional time*

21h 28m

Average total duration

20h 58m

Onboard

+

30m

Additional time*

21h 8m

Average total duration

20h 38m

Onboard

+

30m

Additional time*

2.7 - 5.5kg

CO2 emissions

0.9 - 2.3kg

CO2 emissions

Lowest

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Pisa to Brussels flight times

The table below shows live departures for Pisa to Brussels flights for today, Saturday, December 20. You can also manually refresh the results below to see updated flight journeys.

Last updated at 4:25 AM
ProviderDepartsDurationArrivesTransfers
Tickets
ryanair4:55 PM Pisa
1h45
6:40 PM Brussels0 transfersDirect
Sunday, December 21
ryanair4:00 AM Pisa
1h50
5:50 AM Brussels0 transfersDirect

This is the last flight of the day.

Find all the dates and times for this journey

How far in advance should I book flight tickets from Pisa to Brussels?

The best time to book your flight from Pisa to Brussels is 56 days before departure. See how prices for flights change on the Pisa to Brussels route.
Prices are for one-way tickets for one passenger from Pisa to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your flight from Pisa to Brussels.

Compare prices and tickets Pisa to Brussels by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Dec 21
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Airlines: Ryanair, KM Malta Airlines, Air Dolomiti, Vueling Airlines from Pisa to BrusselsFind the best flights between Pisa to Brussels with Omio's travel partners Ryanair, KM Malta Airlines, Air Dolomiti, Vueling Airlines from $31 (€25). We can find you the best deals, schedules and tickets when comparing and booking the best trip.

Air Dolomiti

About
Air Dolomiti is an Italian regional airline, a wholly-owned subsidiary of Lufthansa, and a member of Lufthansa Regional. Established in 1989, it began operations in 1991 with the goal of connecting smaller Italian cities to the rest of Europe.The airline primarily operates routes from various Italian destinations to and from Lufthansa's main hubs in Munich and Frankfurt, Germany. As of August 2025, Air Dolomiti serves 26 destinations in Italy and other European countries. Its fleet, which has evolved over the years to include Embraer 190 and 195 aircraft, is known for its focus on passenger comfort and Italian elegance in its inflight service.
Luggage & cancellation policy
Average Duration
9h 10m
Cheapest Price
$154 (€123)
Luggage included
1 carry-on bag (8kg, 55x40x23cm) and 1 personal item (40x30x10cm)
Additional luggage
Up to 23kg per piece, fees apply
Cancellation Policy
Free cancellation within 24 hours of booking if flight is more than 7 days away
Pregnant on board
Pregnant women can travel up to 36th week, medical certificate required after 28th week
Unaccompagned minor
Children aged 5-11 can travel unaccompanied with mandatory assistance service, must be booked in advance
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
Pets
Small pets in cabin allowed, max 8kg including carrier, must be booked in advance
Entertaiment on board

Vueling Airlines

About
Vueling is a Spanish low-cost airline and one of the largest carriers in Europe, offering affordable flights across Spain, Europe, North Africa, and the Middle East. Operating mainly from its hub in Barcelona, Vueling provides a modern fleet with flexible fare options to suit different types of travelers. Passengers can choose from basic low-cost tickets to fares that include extras such as seat selection, checked baggage, and priority boarding. With WiFi and onboard services available on many routes, Vueling is a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
9h 40m
Cheapest Price
$89 (€72)
Luggage included
1 cabin bag (40x20x30 cm)
Additional luggage
Extra cabin bag (55x40x20 cm) and checked baggage available for purchase
Cancellation Policy
Free cancellation within 24h of booking if flight is more than 7 days away. After that, cancellation fees apply based on fare type
Pregnant on board
Pregnant women can fly up to week 36 (32 for multiple pregnancies). Medical certificate required after week 28
Unaccompagned minor
Available for children aged 5-11, must be booked at least 48h in advance. Service fee applies
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
Pets
Small pets in cabin allowed, max 8kg including carrier. Must be booked in advance
Entertaiment on board

KM Malta Airlines

About
Malta Air is a low-cost airline that began operations in 2019, initially as a joint venture between Ryanair and the Government of Malta. Ryanair acquired full ownership of the company in 2025. The airline operates from Malta International Airport and has expanded its network to include numerous routes across Europe, the Middle East, and North Africa. Malta Air primarily utilizes Boeing 737-800 and Boeing 737 MAX 200 aircraft, focusing on high-density, short to medium-haul flights. As a low-cost carrier, it offers an Economy Class service with options for purchasing snacks and beverages onboard.
Luggage & cancellation policy
KM Malta Airlines frequency
2 a day
Luggage included
1 small personal item (40x20x25 cm) included
Additional luggage
Additional cabin bag (55x40x20 cm) and checked baggage available for purchase
Cancellation Policy
Free cancellation within 24h of booking if flight is more than 7 days away
Pregnant on board
Pregnant women can travel up to the end of 36th week, medical certificate required after 28th week
Unaccompagned minor
Available for children aged 5-11, must be booked at least 48h in advance
Amenities on board the airplane
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested at least 48h before departure
Pets
Small pets in cabin allowed, max 8kg including carrier

Ryanair

About
Ryanair is one of Europe’s largest and most popular low-cost airlines, headquartered in Ireland. It offers affordable flights to destinations across the continent, often operating to smaller or secondary airports outside major cities to keep fares low. All Ryanair tickets include an allowance for one small personal bag, with additional fees for cabin baggage and checked luggage. Known for its extensive network and budget-friendly fares, Ryanair makes it easy to travel quickly and affordably to popular European destinations.
Luggage & cancellation policy
Average Duration
1h 40m
Cheapest Price
$31 (€25)
Ryanair frequency
1 a day
Luggage included
One small personal bag (40x20x25cm)
Additional luggage
10kg bag (55x40x20cm) or 20kg checked bag available for purchase
Cancellation Policy
Non-refundable tickets. Flight changes possible with fee plus fare difference. Free changes within 24h of booking
Pregnant on board
Up to 28th week of pregnancy can fly freely. Between 28-36 weeks, medical certificate required. Not allowed after 36 weeks
Unaccompagned minor
Unaccompanied minor service available for ages 5-12, €60 per flight. Must be booked at least 7 days before departure
Amenities on board the airplane
Accessibility
Ryanair provides assistance for passengers with reduced mobility, must be booked at least 48 hours before flight

FAQs: Pisa to Brussels Flight

Find answers to the most common questions about traveling from Pisa to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from Pisa to Brussels can start from as little as $29 (€23) when you book in advance. The average flight ticket price for Pisa to Brussels is $198 (€159); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Pisa to Brussels is 1 h 50 min   to travel the 567 mile (914 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Pisa to Brussels leaves at 1: 51AM. Plan your trip with the Journey Planner   from Omio.
The latest flight from Pisa to Brussels leaves at 10: 20PM.
For the best Pisa to Brussels flight to purchase, you can travel safely and comfortably with Ryanair, Air Dolomiti, Vueling Airlines or Transavia Airlines. However, it's always good to check all possible airlines with services to Brussels from Pisa to compare what amenities they may offer.

Flights from Pisa to Brussels generally leave from Pisa International Airport and arrive in Brussels Airport.

Pisa International Airport is 3.8 km away from Pisa city centre and Brussels Airport is 16.8 km from Brussels city centre.

The cheapest month for a flight from Pisa to Brussels is December.
It's helpful to compare your options as there are 3 ways to travel to Brussels from Pisa including taking a train, bus or flight.
Since both Pisa and Brussels are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
The best events to attend in Brussels include:
  • Ommegang, a historical pageant celebrating the medieval heritage of Brussels
  • Brussels Flower Carpet, a stunning floral display in the Grand Place every two years
  • Brussels Jazz Marathon, a weekend of free jazz performances across the city
  • Belgian Beer Weekend, a festival showcasing Belgium's rich beer culture with tastings and workshops.
The best holidays to experience in Brussels include:
  • New Year's Day, a time for fresh beginnings and local celebrations
  • Easter Monday, a public holiday with family gatherings and spring festivities
  • Ascension Day, a day off for locals to enjoy the early summer weather
  • National Day, celebrating Belgium's independence with parades and fireworks
  • All Saints' Day, a day for remembrance and autumn reflections.
The best seasons to visit Brussels are Spring, Summer or Fall. The best weather to explore Brussels is during April-June or September-October.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e. G. 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs).
Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you.
Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.

popular airports

Popular airports from Pisa to Brussels

Pisa
Brussels
The major airport for departures in Pisa is Pisa International Airport. Find all the information you need to know about services, amenities and connections at Pisa International Airport for your trip from Pisa to Brussels.
Amenities at airport
WifiWifi
ShoppingShopping
ParkingParking
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
ShowerShower
LoungeLounge
Lost and Found OfficeLost and Found Office
information
ticketOfficeHours
Distance to city center
2 km
carConnection
Car connection
Via Aurelia, Exit Pisa Centro
Wifi
Wifi
  • Free Wi-Fi available throughout the airport.
Shopping
Shopping
  • Shops include duty-free and local specialty stores, located in the departures area.
Parking
Parking
  • Parking available near the terminal, approximately 2.5€ per hour.
Taxis
Taxis
  • Available outside the terminal.
Accessibility
Accessibility
  • Elevators, ramps.
WC
WC
  • Available throughout the airport.
Shower
Shower
  • Yes
Lounge
Lounge
  • Lounge access available with the Galilei VIP Lounge, offering refreshments and Wi-Fi.
Lost and Found Office
Lost and Found Office
  • Located in the arrivals area, near baggage claim.
Public transit options for Pisa International Airport
  • Bus: LAM Rossa
  • Train: PisaMover

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