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The cheapest and fastest buses from Lyon to Brussels
Showing times and prices for Jan 20
Cheapest price
$27
Average price
$45
Fastest journey
7 h 50 m
Average duration
10 h 34 m
Buses per day
6
Distance
569 km
Cheap tickets
The best way to find a cheap bus ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $45 if you buy it on the day, but the cheapest tickets can be found for only $27.
Fast buses
Of the 6 buses that leave Lyon for Brussels on Tue, Jan 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jan 20 the direct buses cover the 569 km distance in an average of 10 h 34 m but if you time it right, some buses will get you there in just 7 h 50 m .
On Tue, Jan 20 the slowest buses will take 12 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5132 · 165711:59PM12h01
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)12:00PMBrussels, Brussels South (Gare du Midi)
$271One-way
1 transfer
5288 · 146602:25AM11h05
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)01:30PMBrussels, Brussels South (Gare du Midi)
$271One-way
1 transfer
5808 · 165712:55AM11h05
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)12:00PMBrussels, Brussels South (Gare du Midi)
$351One-way
1 transfer
FlixBus09:25PM10h50
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)08:15AMBrussels, Brussels South (Gare du Midi)
$381One-way
0 transfers
FlixBus · FlixBus · FlixBus12:50AM14h55
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)03:45PMBrussels, Brussels South (Gare du Midi)
$561One-way
2 transfers
09:00AM7h50
Lyon04:50PMBrussels
$891One-way
0 transfers
FlixBus09:25PM10h50
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)08:15AMBrussels, Brussels South (Gare du Midi)
$381One-way
0 transfers
5288 · 146602:25AM11h05
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)01:30PMBrussels, Brussels South (Gare du Midi)
$271One-way
1 transfer
5808 · 165712:55AM11h05
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)12:00PMBrussels, Brussels South (Gare du Midi)
$351One-way
1 transfer
5132 · 165711:59PM12h01
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)12:00PMBrussels, Brussels South (Gare du Midi)
$271One-way
1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €21. For those with little time consider booking a flight which can get you there in 1h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €21, and a flight costs an average of €158.
Distance: 353 miles (569 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€56 Average price Cheapest | €130 Average price | €286 Average price |
9h 52m Average total duration 9h 22m Onboard + 30m Additional time* | 4h 21m Average total duration 3h 51m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 1h 59m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Lyon to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:10AM | Arrival Time 12:20PM | Duration 12h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $56 |
Operator FlixBus | Departure Time 12:50AM | Arrival Time 12:45PM | Duration 11h55 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $51 |
Operator BlaBlaCar Bus | Departure Time 12:55AM | Arrival Time 12:00PM | Duration 11h05 | Departure days Tue | Cheapest price $35 |
Operator BlaBlaCar Bus | Departure Time 01:30AM | Arrival Time 12:00PM | Duration 10h30 | Departure days Fri, Sat, Sun | Cheapest price $27 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 01:40PM | Duration 12h00 | Departure days Mon, Thu, Fri | Cheapest price $56 |
Operator FlixBus | Departure Time 01:45AM | Arrival Time 01:40PM | Duration 11h55 | Departure days Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 03:50PM | Duration 14h00 | Departure days Sun | Cheapest price $59 |
Operator BlaBlaCar Bus | Departure Time 02:25AM | Arrival Time 01:30PM | Duration 11h05 | Departure days Mon, Tue, Sat, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 05:25AM | Arrival Time 05:55PM | Duration 12h30 | Departure days Mon, Fri, Sat | Cheapest price $47 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 05:55PM | Duration 11h30 | Departure days Sun | Cheapest price $68 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 04:50PM | Duration 7h50 | Departure days Tue | Cheapest price $89 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 12:35AM | Duration 15h25 | Departure days Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 09:20AM | Arrival Time 05:00PM | Duration 7h40 | Departure days Sat | Cheapest price $78 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 06:10PM | Duration 7h40 | Departure days Fri | Cheapest price $85 |
Operator BlaBlaCar Bus | Departure Time 10:40AM | Arrival Time 11:35PM | Duration 12h55 | Departure days Thu | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 11:20AM | Arrival Time 07:10PM | Duration 7h50 | Departure days Sat | Cheapest price $63 |
Operator BlaBlaCar Bus | Departure Time 12:00PM | Arrival Time 11:35PM | Duration 11h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 03:05AM | Duration 11h50 | Departure days Mon, Fri, Sat, Sun | Cheapest price $51 |
Operator BlaBlaCar | Departure Time 04:20PM | Arrival Time 12:10AM | Duration 7h50 | Departure days Mon | Cheapest price $75 |
Operator BlaBlaCar | Departure Time 05:20PM | Arrival Time 01:30AM | Duration 8h10 | Departure days Mon | Cheapest price $86 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 02:20AM | Duration 8h00 | Departure days Sun | Cheapest price $64 |
Operator BlaBlaCar Bus | Departure Time 08:40PM | Arrival Time 06:20AM | Duration 9h40 | Departure days Mon, Fri | Cheapest price $33 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 08:15AM | Duration 10h50 | Departure days Everyday | Cheapest price $34 |
Operator BlaBlaCar Bus | Departure Time 10:45PM | Arrival Time 08:25AM | Duration 9h40 | Departure days Sat, Sun | Cheapest price $33 |
Operator BlaBlaCar Bus | Departure Time 11:59PM | Arrival Time 12:00PM | Duration 12h01 | Departure days Tue, Wed | Cheapest price $27 |
Live departures
Lyon to Brussels bus times
The table below shows live departures for Lyon to Brussels buses for today, Monday, January 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at 1:48 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 4:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 12h30 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 58074 · 50337 | 11:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h35 | 10:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 2:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h50 | 2:05 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 50805 | 7:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 9h40 | 5:20 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| FlixBus | 8:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 10h50 | 7:15 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 14h55 | 2:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| 5808 · 1657 | 11:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h05 | 11:00 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| Tuesday, January 20 | |||||
| 5288 · 1466 | 1:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h05 | 12:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, bus, or flight
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Journey information
Overview: Bus from Lyon to Brussels
France
Belgium
Buses from Lyon to Brussels run on average 18 times per day, taking around 9h 22m. Cheap bus tickets for this journey start at $26 (€21) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 353 miles (569 km) distance in 9h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 353 miles (569 km) |
Average bus duration 9h 22m |
Cheapest ticket price $26 (€21) |
Buses per day 18 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 00:05 |
Last bus 23:55 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Lyon to Brussels start from as low as $26 (€21) if booked well in advance.
- Standard Fares: Typically, trains cost $70 (€56) depending on the train type and class.
Journey Duration & Frequency
- On average there are 18 daily trains from Lyon to Brussels with 3 direct service.
- The fastest trains can take as little as 9h 40m but the average duration is 9h 22m
Train Operators
- Travel from Lyon to Brussels with BlaBlaCar Bus, FlixBus, and BlaBlaCar
- The most booked train company for this route on Omio is BlaBlaCar Bus.
Stations & Schedule
- Most trains depart from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi)
- First train typically departs at 12:05 AM and the last at 11:55 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Lyon to BrusselsYou can travel by bus between Lyon to Brussels with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as $26 (€21). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
$28 (€22)
FlixBus frequency
13 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
9h 40m
Cheapest Price
$28 (€22)
BlaBlaCar Bus frequency
7 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
2 a day
FAQs: Bus from Lyon to Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Lyon to Brussels can start from as little as $30 (€24) when you book in advance. The average bus ticket price for Lyon to Brussels is $70 (€57); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Lyon to Brussels bus travel time is 9 h 40 min for the 352 mile (568 km) long route, but the duration can vary if you travel on weekends and holidays.
The first bus from Lyon to Brussels leaves at 12: 30AM. Plan your trip with the Journey Planner from Omio.
The last bus from Lyon to Brussels leaves at 10: 40PM.
Yes, it is possible to travel from Lyon to Brussels without having to change trains with FlixBus. There are 3 direct buses from Lyon to Brussels each day. There may be fewer direct services available on weekends or holidays.
For the best Lyon to Brussels bus to book, you can travel safely and comfortably with BlaBlaCar Bus, FlixBus or BlaBlaCar. However, it's always good to check all possible bus providers with services from Lyon to Brussels to compare what amenities they may offer.
When departing from Lyon, you have various bus station options to start your journey from including Lyon, Perrache Bus Station and Lyon, Gare Perrache. When arriving in Brussels, you can end your trip in bus stations like Bruxelles, Gare du Nord and Brussels, Brussels South (Gare du Midi).
Passengers board the bus most frequently from Lyon, Perrache Bus Station, which is located around 1.4 miles (2.3 km) away from the city centre, and they get off the bus at Bruxelles, Gare du Nord, located 1.1 miles (1.7 km) away from the city centre.
The cheapest month for a bus from Lyon to Brussels is October.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Brussels including taking a bus, train or flight.
Yes, the following accessibility options are available when taking the bus from Lyon to Brussels:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Lyon to Brussels for bus companies BlaBlaCar Bus and FlixBus.
Some of the most interesting sights to explore in Brussels are:
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Yes, bikes are allowed on board the bus with bus companies BlaBlaCar Bus and FlixBus.
Whether you can cancel your bus ticket from Lyon to Brussels depends on the bus providers:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Lyon to Brussels, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Lyon to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Lyon to Brussels:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Lyon to Brussels:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Lyon to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
You can reserve your seat on the bus from Lyon to Brussels with the following bus companies: BlaBlaCar Bus and FlixBus
Yes, there are USB plugs on board the bus from Lyon to Brussels with the following bus providers: BlaBlaCar Bus and FlixBus.
Yes, there is Wifi on board the bus from Lyon to Brussels with the following bus providers: BlaBlaCar Bus and FlixBus.
popular bus stations
Popular bus stations from Lyon to Brussels
Lyon
Brussels
The major bus station for departures in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip from Lyon to Brussels.
Lyon, Gare Routière de Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
Cours de VerdunWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Lyon, Gare Routière de Perrache
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, St Exupéry Aéroport
information
Lyon, Gare Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
Cours de Verdun RambaudWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available on the concourse.
Public transit options for Lyon, Gare Perrache
- Bus: C21, C22, S1 Metro: A Train: TER
The major bus station for arrivals in Brussels is Brussels, Brussels South (Gare du Midi). Find all the information you need to know about services, amenities and connections at Brussels, Brussels South (Gare du Midi) for your trip to Brussels from Lyon.
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
2 kmCar connection
Avenue FonsnyWifi
- Free Wi-Fi
Dining
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels, Brussels South (Gare du Midi)
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:59
Distance to city center
1 kmCar connection
Rue du ProgrèsWifi
- Free Wi-Fi
Dining
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels-Noord
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Brussels, Gare Du Midi
information
Most popular bus connections from Lyon
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Lyon
Most popular bus connections to Brussels
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