- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Sep 02
$30
Average ticket price on Sep 02
$51
Fastest journey on Sep 02
10 h 40 m
Average journey duration on Sep 02
11 h 12 m
Buses on Sep 02
10
Distance
569 km
The best way to find a cheap bus ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $30.
On Wed, Sep 02, we found 10 buses from Lyon to Brussels, including 1 direct services.
On Wed, Sep 02 the direct buses cover the 569 km distance in an average of 11 h 12 m but if you time it right, some buses will get you there in just 10 h 40 m .
On Wed, Sep 02 the slowest buses will take 11 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
83134 · 98080
FlixBus · FlixBus
50470 · 50448
FlixBus · FlixBus
FlixBus · FlixBus
83134 · 98080
FlixBus
5808 · 1657
50470 · 50448
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $47 For those with little time, consider booking a flight, which has an average total journey time of 4h 25m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $47, while a flight costs an average of $259.
Distance: 353 miles (569 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$47 Average price Cheapest | $143 Average price | $259 Average price | $198 Average price (fuel + tolls) |
8h 30m Average total duration 8h 0m Onboard + 30m Additional time* | 5h 14m Average total duration 4h 44m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 2h 25m Onboard + 2h 0m Additional time* | 7h 28m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Brussels:
A bus is $96 (€78) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $143 (€116).
A bus is $212 (€171) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $259 (€210).
Other travel options to Brussels take longer:
Train takes on average 4h 44m.
Bus takes on average 8h 0m.
Tickets start at around $47 (€38) compared to roughly $198 (€160) in fuel and tolls — a saving of about $151 (€122). The journey takes 8h 0m versus 7h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar Bus, FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:10AM | Arrival Time 12:20PM | Duration 12h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $31 |
Operator FlixBus | Departure Time 12:50AM | Arrival Time 12:45PM | Duration 11h55 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $39 |
Operator BlaBlaCar Bus | Departure Time 12:55AM | Arrival Time 12:00PM | Duration 11h05 | Departure days Wed, Thu | Cheapest price $32 |
Operator BlaBlaCar Bus | Departure Time 01:20AM | Arrival Time 12:00PM | Duration 10h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $29 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 01:40PM | Duration 12h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 05:00AM | Arrival Time 03:45PM | Duration 10h45 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $33 |
Operator BlaBlaCar Bus | Departure Time 08:30AM | Arrival Time 07:10PM | Duration 10h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 04:10PM | Duration 7h10 | Departure days Mon | Cheapest price $53 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 12:35AM | Duration 15h20 | Departure days Thu | Cheapest price $39 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 05:00PM | Duration 7h00 | Departure days Wed | Cheapest price $64 |
Operator BlaBlaCar | Departure Time 10:40AM | Arrival Time 06:10PM | Duration 7h30 | Departure days Fri | Cheapest price $84 |
Operator BlaBlaCar Bus | Departure Time 10:40AM | Arrival Time 10:30PM | Duration 11h50 | Departure days Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 10:50AM | Arrival Time 06:50PM | Duration 8h00 | Departure days Thu | Cheapest price $74 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 07:00PM | Duration 8h00 | Departure days Fri | Cheapest price $72 |
Operator BlaBlaCar | Departure Time 11:20AM | Arrival Time 07:10PM | Duration 7h50 | Departure days Mon | Cheapest price $55 |
Operator BlaBlaCar Bus | Departure Time 12:00PM | Arrival Time 11:35PM | Duration 11h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 12:10PM | Arrival Time 07:30PM | Duration 7h20 | Departure days Fri | Cheapest price $63 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 09:00PM | Duration 8h00 | Departure days Sun | Cheapest price $56 |
Operator BlaBlaCar | Departure Time 01:20PM | Arrival Time 08:50PM | Duration 7h30 | Departure days Sat | Cheapest price $51 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 12:35AM | Duration 11h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $32 |
Operator BlaBlaCar | Departure Time 01:40PM | Arrival Time 09:10PM | Duration 7h30 | Departure days Sat | Cheapest price $116 |
Operator TER | Departure Time 02:16PM | Arrival Time 08:00AM | Duration 17h44 | Departure days Mon, Fri | Cheapest price $84 |
Operator TER | Departure Time 02:52PM | Arrival Time 08:00AM | Duration 17h08 | Departure days Sun | Cheapest price $90 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 11:00PM | Duration 8h00 | Departure days Tue, Sun | Cheapest price $75 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 03:05AM | Duration 11h50 | Departure days Everyday | Cheapest price $31 |
Operator TER | Departure Time 03:16PM | Arrival Time 08:00AM | Duration 16h44 | Departure days Mon, Fri, Sun | Cheapest price $84 |
Operator BlaBlaCar | Departure Time 03:20PM | Arrival Time 11:00PM | Duration 7h40 | Departure days Wed | Cheapest price $109 |
Operator BlaBlaCar Bus | Departure Time 03:30PM | Arrival Time 02:13AM | Duration 10h43 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar Bus | Departure Time 04:00PM | Arrival Time 03:05AM | Duration 11h05 | Departure days Tue | Cheapest price $46 |
Operator TER | Departure Time 04:16PM | Arrival Time 08:00AM | Duration 15h44 | Departure days Mon, Fri | Cheapest price $84 |
Operator SNCF | Intercités | Departure Time 05:04PM | Arrival Time 08:00AM | Duration 14h56 | Departure days Mon, Fri, Sun | Cheapest price $80 |
Operator TER | Departure Time 05:16PM | Arrival Time 08:00AM | Duration 14h44 | Departure days Mon, Fri, Sun | Cheapest price $84 |
Operator SNCF | TGV INOUI | Departure Time 06:00PM | Arrival Time 08:00AM | Duration 14h00 | Departure days Sun | Cheapest price $119 |
Operator TER | Departure Time 06:16PM | Arrival Time 08:00AM | Duration 13h44 | Departure days Sun | Cheapest price $90 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 02:10AM | Duration 7h50 | Departure days Sun | Cheapest price $61 |
Operator TER | Departure Time 07:16PM | Arrival Time 08:00AM | Duration 12h44 | Departure days Sun | Cheapest price $90 |
Operator BlaBlaCar | Departure Time 08:00PM | Arrival Time 03:50AM | Duration 7h50 | Departure days Wed | Cheapest price $67 |
Operator BlaBlaCar | Departure Time 08:50PM | Arrival Time 04:00AM | Duration 7h10 | Departure days Tue | Cheapest price $121 |
Operator BlaBlaCar Bus | Departure Time 09:10PM | Arrival Time 08:00AM | Duration 10h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 08:15AM | Duration 10h50 | Departure days Everyday | Cheapest price $52 |
The table below shows live departures for Lyon to Brussels buses for today, Tuesday, September 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h50 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
54032 · 50448 | 4:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h05 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
51095 | 9:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h50 | 8:00 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
FlixBus | 9:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h50 | 8:15 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| Wednesday, September 2 | |||||
FlixBus · FlixBus | 12:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h10 | 12:20 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 12:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h55 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
5808 · 1657 | 12:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h05 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 1:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h10 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus | 1:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h00 | 1:40 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 5:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h55 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
83134 · 98080 | 8:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h40 | 7:10 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lyon to Brussels run on average 14 times per day, taking around 8h 0m. Cheap bus tickets for this journey start at $27 (€22) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 353 miles (569 km) distance in 10h 15m.
Distance 353 miles (569 km) |
Average bus duration 8h 0m |
Cheapest ticket price $27 (€22) |
Buses per day 14 |
Direct buses 3 |
Fastest bus 10h 15m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 84 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Lyon to Brussels buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Lyon and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
Here are some other resources that might have the information you need