The cheapest and fastest buses from Prague to Brussels
Cheapest price
$83
Average price
$91
Fastest journey
15 h 5 m
Average duration
16 h 19 m
Buses per day
11
Distance
717 km
The best way to find a cheap bus ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around $91 if you buy it on the day, but the cheapest tickets can be found for only $83.
Of the 11 buses that leave Prague for Brussels on Sun, Jan 18, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jan 18 the direct buses cover the 717 km distance in an average of 16 h 19 m but if you time it right, some buses will get you there in just 15 h 5 m .
On Sun, Jan 18 the slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a flight costs an average of €34.
Distance: 445 miles (717 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€66 Average price Cheapest | €192 Average price | €161 Average price |
14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* | 13h 42m Average total duration 13h 12m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:55AM | Arrival Time 01:45AM | Duration 17h50 | Departure days Thu, Fri, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 01:45AM | Duration 17h15 | Departure days Sat | Cheapest price $97 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 01:45AM | Duration 15h55 | Departure days Thu, Fri, Sun | Cheapest price $75 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 03:25AM | Duration 17h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 03:25AM | Duration 16h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 03:25AM | Duration 16h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 07:20AM | Duration 18h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 07:20AM | Duration 18h25 | Departure days Sat, Sun | Cheapest price $90 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 07:20AM | Duration 16h50 | Departure days Sat, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 07:20AM | Duration 15h05 | Departure days Everyday | Cheapest price $62 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 12:45PM | Duration 19h00 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:25PM | Duration 18h25 | Departure days Everyday | Cheapest price $69 |
Operator Regiojet | Departure Time 06:00PM | Arrival Time 06:00AM | Duration 12h00 | Departure days Tue, Fri | Cheapest price $78 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 03:35PM | Duration 18h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $82 |
Live departures
Prague to Brussels bus times
The table below shows live departures for Prague to Brussels buses for today, Saturday, January 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:30 AM Praha, ÚAN Florenc | 17h15 | 12:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:55 AM Praha, Zličín | 17h30 | 2:25 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 9:30 AM Praha, ÚAN Florenc | 16h55 | 2:25 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 9:55 AM Praha, Na Knížecí | 16h30 | 2:25 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 18h30 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:55 AM Praha, Zličín | 18h25 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 16h50 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus | 3:15 PM Praha, ÚAN Florenc | 15h05 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 19h00 | 11:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 5:00 PM Praha, ÚAN Florenc | 18h25 | 11:25 AM Brussels, Avenue des Magnolias (King Baudouin) | 1 transfer | |
FlixBus · FlixBus | 7:40 PM Praha, Na Knížecí | 18h55 | 2:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 17
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Jan 20
Jan 21
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Jan 23
Jan 24
Jan 25
Jan 26
Jan 27
Jan 28
Jan 29
Jan 30
Jan 31
Feb 01
Feb 02
Feb 03
Feb 04
Feb 05
Feb 06
Journey information
Overview: Bus from Prague to Brussels
Buses from Prague to Brussels run on average 25 times per day, taking around 13h 39m. Cheap bus tickets for this journey start at $33 (€27) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 445 miles (717 km) distance in 12h 0m.
Distance 445 miles (717 km) |
Average bus duration 13h 39m |
Cheapest ticket price $33 (€27) |
Buses per day 25 |
Direct buses 3 |
Fastest bus 12h 0m |
First bus 00:10 |
Last bus 23:50 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Prague to Brussels start from as low as $33 (€27) if booked well in advance.
- Standard Fares: Typically, trains cost $81 (€66) depending on the train type and class.
Journey Duration & Frequency
- On average there are 25 daily trains from Prague to Brussels with 3 direct service.
- The fastest trains can take as little as 12h 0m but the average duration is 13h 39m
Train Operators
- Travel from Prague to Brussels with FlixBus and BlaBlaCar Bus
- The most booked train company for this route on Omio is FlixBus.
Stations & Schedule
- Most trains depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi)
- First train typically departs at 12:10 AM and the last at 11:50 PM
Bus providers: FlixBus, BlaBlaCar Bus from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus for as low as $33 (€27). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Bus from Prague to Brussels
Find answers to the most common questions about traveling from Prague to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Prague, Central Train Station, which is located around 1.8 miles (2.9 km) away from the city centre, and they get off the bus at Bruxelles, Gare du Nord, located 1.1 miles (1.7 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
To find the cheapest bus tickets for your trip from Prague to Brussels, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Brussels
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
More options for your journey from Prague to Brussels
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