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The cheapest and fastest buses from Prague to Brussels
Showing times and prices for Dec 04
Cheapest price
$73
Average price
$95
Fastest journey
15 h 5 m
Average duration
16 h 58 m
Buses per day
13
Distance
717 km
Cheap tickets
The best way to find a cheap bus ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around $95 if you buy it on the day, but the cheapest tickets can be found for only $73.
Fast buses
Of the 13 buses that leave Prague for Brussels on Thu, Dec 04, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Dec 04 the direct buses cover the 717 km distance in an average of 16 h 58 m but if you time it right, some buses will get you there in just 15 h 5 m .
On Thu, Dec 04 the slowest buses will take 18 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus06:00PM18h25
Praha, ÚAN Florenc12:25PMBrussels, Avenue des Magnolias (King Baudouin)
$731One-way
1 transfer
FlixBus · FlixBus05:45PM19h00
Praha, Na Knížecí12:45PMBrussels, Brussels South (Gare du Midi)
$731One-way
1 transfer
FlixBus · FlixBus08:40PM18h55
Praha, Na Knížecí03:35PMBrussels, Brussels South (Gare du Midi)
$741One-way
1 transfer
FlixBus · FlixBus08:15PM19h20
Praha, ÚAN Florenc03:35PMBrussels, Brussels South (Gare du Midi)
$741One-way
1 transfer
FlixBus · FlixBus · FlixBus04:45PM19h40
Prague, Central Train Station12:25PMBrussels, Avenue des Magnolias (King Baudouin)
$741One-way
2 transfers
FlixBus04:15PM15h05
Praha, ÚAN Florenc07:20AMBrussels, Brussels South (Gare du Midi)
$841One-way
0 transfers
FlixBus · FlixBus10:55AM16h40
Praha, Na Knížecí03:35AMBrussels, Brussels South (Gare du Midi)
$1271One-way
1 transfer
FlixBus · FlixBus10:30AM17h05
Praha, ÚAN Florenc03:35AMBrussels, Brussels South (Gare du Midi)
$1271One-way
1 transfer
FlixBus · FlixBus · FlixBus09:55AM17h40
Praha, Zličín03:35AMBrussels, Brussels South (Gare du Midi)
$1131One-way
2 transfers
FlixBus · FlixBus · FlixBus07:20AM18h20
Praha, ÚAN Florenc01:40AMBrussels, Brussels South (Gare du Midi)
$1351One-way
2 transfers
Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a flight costs an average of €34.
Distance: 445 miles (717 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€66 Average price Cheapest | €192 Average price | €161 Average price |
14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* | 13h 42m Average total duration 13h 12m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:50AM | Arrival Time 03:35AM | Duration 21h45 | Departure days Everyday | Cheapest price $58 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 01:40AM | Duration 18h20 | Departure days Thu | Cheapest price $135 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 03:25AM | Duration 19h05 | Departure days Sat, Sun | Cheapest price $124 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 01:40AM | Duration 17h10 | Departure days Mon, Fri, Sat, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 03:35AM | Duration 18h25 | Departure days Tue | Cheapest price $94 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 03:35AM | Duration 18h05 | Departure days Tue | Cheapest price $94 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 03:35AM | Duration 17h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 03:35AM | Duration 17h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 03:35AM | Duration 16h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 07:20AM | Duration 18h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $59 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 07:20AM | Duration 18h25 | Departure days Sun | Cheapest price $90 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 07:20AM | Duration 16h50 | Departure days Sat, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 07:20AM | Duration 16h15 | Departure days Sat | Cheapest price $77 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 10:00AM | Duration 17h45 | Departure days Everyday | Cheapest price $58 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 12:25PM | Duration 19h40 | Departure days Everyday | Cheapest price $59 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 12:45PM | Duration 19h00 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:25PM | Duration 18h25 | Departure days Everyday | Cheapest price $59 |
Operator Regiojet | Departure Time 06:00PM | Arrival Time 06:00AM | Duration 12h00 | Departure days Tue, Fri | Cheapest price $69 |
Operator BlaBlaCar Bus | Departure Time 07:00PM | Arrival Time 01:30PM | Duration 18h30 | Departure days Thu, Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 03:35PM | Duration 19h20 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 03:35PM | Duration 18h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $69 |
Live departures
Prague to Brussels bus times
The table below shows live departures for Prague to Brussels buses for today, Wednesday, December 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at 12:51 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 4:50 AM Prague, Central Train Station | 21h45 | 2:35 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 8:55 AM Praha, Zličín | 17h40 | 2:35 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus | 9:30 AM Praha, ÚAN Florenc | 17h05 | 2:35 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 9:55 AM Praha, Na Knížecí | 16h40 | 2:35 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus | 3:15 PM Praha, ÚAN Florenc | 15h05 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| FlixBus · FlixBus | 3:15 PM Praha, ÚAN Florenc | 17h45 | 9:00 AM Brussels, Gare Du Midi | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 3:45 PM Prague, Central Train Station | 19h40 | 11:25 AM Brussels, Avenue des Magnolias (King Baudouin) | 2 transfers | |
| FlixBus · FlixBus | 5:00 PM Praha, ÚAN Florenc | 18h25 | 11:25 AM Brussels, Avenue des Magnolias (King Baudouin) | 1 transfer | |
| FlixBus · FlixBus | 7:15 PM Praha, ÚAN Florenc | 19h20 | 2:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 7:40 PM Praha, Na Knížecí | 18h55 | 2:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Prague to Brussels
Czechia
Belgium
Buses from Prague to Brussels run on average 25 times per day, taking around 13h 39m. Cheap bus tickets for this journey start at $33 (€27) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 445 miles (717 km) distance in 12h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 445 miles (717 km) |
Average bus duration 13h 39m |
Cheapest ticket price $33 (€27) |
Buses per day 25 |
Direct buses 3 |
Fastest bus 12h 0m |
First bus 00:10 |
Last bus 23:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, BlaBlaCar Bus from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus for as low as $33 (€27). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 50m
Cheapest Price
$32 (€25)
FlixBus frequency
29 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
15h 35m
Cheapest Price
$79 (€64)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
FAQs: Bus from Prague to Brussels
Find answers to the most common questions about traveling from Prague to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Prague to Brussels can start from as little as $49 (€40) when you book in advance. The average bus ticket price for Prague to Brussels is $82 (€66); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Prague to Brussels bus time is 12 h covering the 445 mile (717 km) long route, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Prague to Brussels leaves at 2: 50AM. Plan your trip with the Journey Planner from Omio.
The last bus from Prague to Brussels leaves at 10: 50PM.
Yes, it is possible to travel from Prague to Brussels without having to change trains with FlixBus. There are 4 direct buses from Prague to Brussels each day. There may be fewer direct services available on weekends or holidays.
For the journey from Prague to Brussels you can take a bus with FlixBus or BlaBlaCar Bus. Be sure to check out all possible bus companies that offer services from Prague to Brussels on Omio to compare what amenities they may have.
Passengers board the bus most frequently from Prague, Central Train Station, which is located around 1.8 miles (2.9 km) away from the city centre, and they get off the bus at Bruxelles, Gare du Nord, located 1.1 miles (1.7 km) away from the city centre.
The cheapest month for a bus from Prague to Brussels is December.
It's helpful to compare your options as there are 3 ways to travel between Prague and Brussels including taking a train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Prague to Brussels:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
Yes, there are bathrooms on board the bus from Prague to Brussels for bus companies FlixBus and BlaBlaCar Bus.
Some of the most interesting sights to explore in Brussels are:
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Yes, bikes are allowed on board the bus with bus providers FlixBus and BlaBlaCar Bus.
Whether you can cancel your bus ticket from Prague to Brussels depends on the bus providers:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
To find the cheapest bus tickets for your trip from Prague to Brussels, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Prague to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Prague to Brussels:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Prague to Brussels:
- FlixBus
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Prague to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
You can reserve your seat on the bus from Prague to Brussels with the following bus companies: FlixBus and BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Prague to Brussels with the following bus providers: FlixBus and BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Prague to Brussels with the following bus providers: FlixBus and BlaBlaCar Bus.
popular bus stations
Popular bus stations from Prague to Brussels
Prague
Brussels
The major bus station for departures in Prague is Praha, Na Knížecí. Find all the information you need to know about services, amenities and connections at Praha, Na Knížecí for your trip from Prague to Brussels.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WCinformation
Distance to city center
2 km
Car connection
OstrovskéhoWifi
- Free Wi-Fi
Dining
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Na Knížecí
- Bus: 137, 176, 191 Metro: B
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWC
Ticket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
1 kmCar connection
WilsonovaWifi
- Free Wi-Fi
Dining
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Hlavní Nádraží
- Bus: 135, 175, 207 Metro: C Train: All major s
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
KřižíkovaWifi
- Free Wi-Fi
Dining
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, ÚAN Florenc
- Bus: 133, 135, 175, 207 Metro: B, C
The major bus station for arrivals in Brussels is Brussels-Noord. Find all the information you need to know about services, amenities and connections at Brussels-Noord for your trip to Brussels from Prague.
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:59
Distance to city center
1 kmCar connection
Rue du ProgrèsWifi
- Free Wi-Fi
Dining
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels-Noord
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
2 kmCar connection
Avenue FonsnyWifi
- Free Wi-Fi
Dining
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels, Brussels South (Gare du Midi)
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Brussel-Zuid/Midi
Amenities at bus station
Accessibilityinformation
Distance to city center
1 kmAccessibility
- The place has an entrance that is wheelchair-accessible
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Prague
Most popular bus connections to Brussels
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