Prague to Brussels bus with FlixBus

Tue, Mar 03
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The cheapest and fastest buses from Prague to Brussels

Showing times and prices for Mar 04

Cheapest price

$89

Average price

$109

Fastest journey

15 h 5 m

Average duration

16 h 44 m

Buses per day

8

Distance

717 km

Cheap tickets

The best way to find a cheap bus ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Prague to Brussels will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $89.

Fast buses

Of the 8 buses that leave Prague for Brussels on Wed, Mar 04, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Mar 04 the direct buses cover the 717 km distance in an average of 16 h 44 m but if you time it right, some buses will get you there in just 15 h 5 m .

On Wed, Mar 04 the slowest buses will take 17 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBusFlixBus
04:15PM15h05
Praha, ÚAN Florenc
07:20AMBrussels, Brussels South (Gare du Midi)
$891One-way
0 transfers
FlixBusFlixBus · FlixBus
04:15PM17h45
Praha, ÚAN Florenc
10:00AMBrussels, Gare Du Midi
$1081One-way
1 transfer
FlixBusFlixBus · FlixBus
10:55AM16h40
Praha, Na Knížecí
03:35AMBrussels, Brussels South (Gare du Midi)
$1091One-way
1 transfer
FlixBusFlixBus · FlixBus
11:05AM16h30
Praha, ÚAN Florenc
03:35AMBrussels, Brussels South (Gare du Midi)
$1091One-way
1 transfer
FlixBusFlixBus · FlixBus · FlixBus
09:55AM17h40
Praha, Zličín
03:35AMBrussels, Brussels South (Gare du Midi)
$1101One-way
2 transfers

Travel Information

Compare train, bus, and flight for Prague to Brussels

Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $50. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $50, and a flight costs an average of $26.

Distance: 445 miles (717 km)

Compare bus with

Bus
Most popular
Flight
Train

$84

Average price

Cheapest

$134

Average price

$122

Average price

15h 10m

Average total duration

14h 40m

Onboard

+

30m

Additional time*

6h 21m

Average total duration

Fastest

3h 21m

Onboard

+

3h 0m

Additional time*

12h 17m

Average total duration

11h 47m

Onboard

+

30m

Additional time*

0.7 - 1.8kg

CO2 emissions

2.2 - 4.3kg

CO2 emissions

0.2 - 0.6kg

CO2 emissions

Lowest
FlixBus

Most popular bus company

Ryanair

Most popular airline

Deutsche Bahn

Most popular train company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Prague to Brussels Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
07:55AM
Arrival Time
01:45AM
Duration
17h50
Departure days
Thu
Cheapest price
$100
Operator
FlixBus
Departure Time
09:10AM
Arrival Time
01:45AM
Duration
16h35
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$93
Operator
FlixBus
Departure Time
09:55AM
Arrival Time
03:25AM
Duration
17h30
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$94
Operator
FlixBus
Departure Time
10:35AM
Arrival Time
01:45AM
Duration
15h10
Departure days
Sat
Cheapest price
$108
Operator
FlixBus
Departure Time
10:55AM
Arrival Time
03:25AM
Duration
16h30
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$96
Operator
FlixBus
Departure Time
11:05AM
Arrival Time
01:45AM
Duration
14h40
Departure days
Mon, Tue, Wed, Thu, Fri, Sun
Cheapest price
$93
Operator
FlixBus
Departure Time
12:50PM
Arrival Time
07:20AM
Duration
18h30
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$92
Operator
FlixBus
Departure Time
12:55PM
Arrival Time
07:20AM
Duration
18h25
Departure days
Sat, Sun
Cheapest price
$109
Operator
FlixBus
Departure Time
02:30PM
Arrival Time
07:20AM
Duration
16h50
Departure days
Sat, Sun
Cheapest price
$107
Operator
FlixBus
Departure Time
04:15PM
Arrival Time
07:20AM
Duration
15h05
Departure days
Everyday
Cheapest price
$71
Operator
FlixBus
Departure Time
05:45PM
Arrival Time
12:45PM
Duration
19h00
Departure days
Wed, Thu, Fri
Cheapest price
$92
Operator
FlixBus
Departure Time
06:00PM
Arrival Time
12:25PM
Duration
18h25
Departure days
Everyday
Cheapest price
$92
Operator
Regiojet
Departure Time
06:00PM
Arrival Time
06:00AM
Duration
12h00
Departure days
Tue, Fri
Cheapest price
$70
Operator
FlixBus
Departure Time
06:45PM
Arrival Time
01:55PM
Duration
19h10
Departure days
Fri, Sat
Cheapest price
$97
Operator
BlaBlaCar Bus
Departure Time
07:00PM
Arrival Time
01:30PM
Duration
18h30
Departure days
Thu, Sun
Cheapest price
$77
Operator
FlixBus
Departure Time
08:40PM
Arrival Time
03:35PM
Duration
18h55
Departure days
Tue, Wed
Cheapest price
$127
Operator
FlixBus
Departure Time
09:50PM
Arrival Time
01:55PM
Duration
16h05
Departure days
Thu, Fri, Sat, Sun
Cheapest price
$84
Operator
FlixBus
Departure Time
11:05PM
Arrival Time
01:55PM
Duration
14h50
Departure days
Thu, Fri, Sat, Sun
Cheapest price
$69

Live departures

Prague to Brussels bus times

The table below shows live departures for Prague to Brussels buses for today, Tuesday, March 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at 5:58 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus10:05 AM Praha, ÚAN Florenc
16h30
2:35 AM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus3:15 PM Praha, ÚAN Florenc
15h05
6:20 AM Brussels, Brussels South (Gare du Midi)0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus5:00 PM Praha, ÚAN Florenc
18h25
11:25 AM Brussels, Avenue des Magnolias (King Baudouin)1 transfer
studentagencyconnect_regio_jet(Prague -> London)5:00 PM Praha, ÚAN Florenc
12h00
5:00 AM Brussels, Brussels South (Gare du Midi)0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus7:40 PM Praha, Na Knížecí
18h55
2:35 PM Brussels, Brussels South (Gare du Midi)1 transfer

Find all the dates and times for this journey

Compare prices and tickets Prague to Brussels by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
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Mar 23

Why should you book Prague to Brussels buses with Omio?

FlixBus as well as BlaBlaCar Bus offer buses services from Prague to Brussels.
Omio is an official ticket reseller for all your travel options from Prague to Brussels.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Brussels.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Brussels.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.

Journey information

Overview: Bus from Prague to Brussels

CzechiaCzechia
BelgiumBelgium
Icon of bus

Buses from Prague to Brussels run on average 18 times per day, taking around 14h 40m. Cheap bus tickets for this journey start at $50 (€40) but you can travel from only $17 (€13) by train.

There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 445 miles (717 km) distance in 12h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $17 (€13)
Distance
445 miles (717 km)
Average bus duration
14h 40m
Cheapest ticket price
$50 (€40)
Buses per day
18
Direct buses
2
Fastest bus
12h 0m
First bus
00:10
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $17 (€13)

Bus providers: FlixBus, BlaBlaCar Bus from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus for as low as $17 (€13). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 50m
Cheapest Price
$55 (€44)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
18h 30m
Cheapest Price
$73 (€59)
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

FAQs: Bus from Prague to Brussels

Find answers to the most common questions about traveling from Prague to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Prague to Brussels can start from as little as $50 (€40) when you book in advance. The average bus ticket price for Prague to Brussels is $84 (€67) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Prague to Brussels is 12h 0m to travel the 445 miles (717 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Prague to Brussels leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Prague to Brussels leaves at 11:50 PM.
Yes, there are 2 direct buses a day from Prague to Brussels with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Prague to Brussels, you can count on FlixBus, BlaBlaCar Bus for the best way to get you to Brussels. You can also check all possible bus companies who offer a service between Prague and Brussels and compare the amenities they offer before buying a bus ticket.
When departing from Prague , you have various bus station options to start your journey from including Praha, ÚAN Florenc, Prague, Central Train Station, Praha, Na Knížecí, Praha, Zličín, Praha, M. Horákové (Hradčanská), Praha, Černý Most, Praha, Roztyly, Praha, Letiště Václava Havla, Praha, Nádraží Holešovice . When arriving in Brussels , you can end your journey in bus stations like Brussels, Brussels South (Gare du Midi), Bruxelles, Gare du Nord, Brussels, Avenue des Magnolias (King Baudouin), Brussels, Gare Du Midi, Brussel-Zuid/Midi, Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord), Schaerbeek, Rue du Progrès (Gare du Nord) .Passengers board the bus most frequently from Praha, ÚAN Florenc, which is located around 1 away from the city centre, and they get off the bus at Brussels, Brussels South (Gare du Midi), located 2 away from the city centre.
A trip to Brussels from Prague is worth doing but not as a day trip with a journey time of 12h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Prague to Brussels is April.
It's helpful to compare your options as there are 3 ways to travel between Prague and Brussels including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Prague to Brussels for bus company FlixBus, BlaBlaCar Bus.
Yes, the following accessibility options are available when taking the bus from Prague to Brussels:
  • BlaBlaCar Bus
    • Assistance
    • Priority boarding
    • Accessible seating options.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Brussels are:
  • Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
  • Atomium, an iconic structure and museum offering panoramic views of the city
  • Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
  • Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
  • Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
  • Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
  • Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
  • Sample Belgian chocolates at one of the city's renowned chocolatiers
  • Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
  • Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Whether you can cancel your bus ticket from Prague to Brussels depends on the bus companies:
  • BlaBlaCar Bus
    • You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Prague to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Prague to Brussels:
  • BlaBlaCar Bus
    • One carry-on bag up to 7kg and one checked bag up to 20kg.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Prague to Brussels:
  • BlaBlaCar Bus
    • Additional luggage can be purchased for a fee.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Prague to Brussels. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Prague to Brussels with the following bus company: FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Prague to Brussels with the following bus company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Prague to Brussels with the following bus company: FlixBus, BlaBlaCar Bus.

popular bus stations

Popular bus stations from Prague to Brussels

Prague
Brussels
The major bus station for departures in Prague is Praha, ÚAN Florenc. Find all the information you need to know about services, amenities and connections at Praha, ÚAN Florenc for your trip from Prague to Brussels.
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 06:00-23:00
ticketOfficeHours
Distance to city center
1 km
carConnection
Car connection
Křižíkova
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Cafeteria Florenc (in the station)
  • Bistro Florenc (0.2 km)
  • Restaurace U Rozvařilů (0.5 km).
Taxis
Taxis
  • Available outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available in the station.
Public transit options for Praha, ÚAN Florenc
  • Bus: 133, 135, 175, 207 Metro: B, C
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 00:00-23:59
ticketOfficeHours
Distance to city center
1 km
carConnection
Car connection
Wilsonova
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Czech Bistro (in the station)
  • Fast Food Express (in the station)
  • Bohemian Café (0.2 km).
Taxis
Taxis
  • Available outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available in the station.
Public transit options for Praha, Hlavní Nádraží
  • Bus: 135, 175, 207 Metro: C Train: All major s
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
information
ticketOfficeHours
Distance to city center
2 km
carConnection
Car connection
Ostrovského
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Café Na Knížecí (in the station)
  • Bistro Praha (0.2 km)
  • Restaurace U Knížete (0.5 km).
Taxis
Taxis
  • Available outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available in the station.
Public transit options for Praha, Na Knížecí
  • Bus: 137, 176, 191 Metro: B

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