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The cheapest and fastest buses from Rome to Brussels
Showing times and prices for Feb 20
Cheapest price
$154
Average price
$185
Fastest journey
1 d 2 h 55 m
Average duration
1 d 4 h 1 m
Buses per day
13
Distance
1174 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Brussels will cost around $185 if you buy it on the day, but the cheapest tickets can be found for only $154.
Fast buses
It's difficult to get from Rome to Brussels without transferring at least once.
FlixBus · FlixBus · FlixBus11:35PM31h45
Roma, Autostazione (Metro Anagnina)07:20AMBrussels, Brussels South (Gare du Midi)
$1541One-way
2 transfers
FlixBus · FlixBus · FlixBus12:10PM30h50
Roma, Autostazione Tiburtina07:00PMBrussels, Brussels South (Gare du Midi)
$1651One-way
2 transfers
FlixBus · FlixBus · FlixBus10:55PM32h25
Roma, Autostazione Tiburtina07:20AMBrussels, Brussels South (Gare du Midi)
$1701One-way
2 transfers
FlixBus · FlixBus · FlixBus05:25PM30h05
Roma, Autostazione (Metro Anagnina)11:30PMBrussels, Brussels South (Gare du Midi)
$1751One-way
2 transfers
FlixBus · FlixBus · FlixBus08:00PM29h10
Roma, Autostazione Tiburtina01:10AMBrussels, Brussels South (Gare du Midi)
$1751One-way
2 transfers
FlixBus · FlixBus12:10AM26h55
Roma, Autostazione Tiburtina03:05AMBrussels, Brussels South (Gare du Midi)
$2131One-way
1 transfer
FlixBus · FlixBus08:50AM27h55
Roma, Autostazione Tiburtina12:45PMBrussels, Brussels South (Gare du Midi)
$2191One-way
1 transfer
FlixBus · FlixBus · FlixBus10:45PM28h20
Roma, Autostazione Tiburtina03:05AMBrussels, Brussels South (Gare du Midi)
$1821One-way
2 transfers
FlixBus · FlixBus · FlixBus09:35AM28h20
Roma, Autostazione Tiburtina01:55PMBrussels, Brussels South (Gare du Midi)
$1861One-way
2 transfers
FlixBus · FlixBus · FlixBus07:45AM28h35
Roma, Autostazione Tiburtina12:20PMBrussels, Brussels South (Gare du Midi)
$2061One-way
2 transfers
Travel Information
Compare train, bus, and flight for Rome to Brussels
Omio recommends booking the flight as it is the most popular option from Rome to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from €17. For those with little time consider booking a flight which can get you there in 3h 6m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 2.9kg. The ticket price range depends on the travel mode: a flight costs an average of €17, and a train costs an average of €327.
Distance: 729 miles (1174 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€109 Average price | €90 Average price Cheapest | €327 Average price |
27h 2m Average total duration 26h 32m Onboard + 30m Additional time* | 6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* | 20h 34m Average total duration 20h 4m Onboard + 30m Additional time* |
1.2 - 2.9kg CO2 emissions Lowest | 3.5 - 7.0kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:10AM | Arrival Time 03:05AM | Duration 26h55 | Departure days Everyday | Cheapest price $112 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 12:20PM | Duration 28h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $122 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 03:50PM | Duration 31h00 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $121 |
Operator FlixBus | Departure Time 09:35AM | Arrival Time 01:55PM | Duration 28h20 | Departure days Fri, Sat | Cheapest price $186 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 05:55PM | Duration 31h15 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $107 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 05:55PM | Duration 29h45 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:55PM | Duration 28h50 | Departure days Everyday | Cheapest price $107 |
Operator BlaBlaCar Bus | Departure Time 03:20PM | Arrival Time 04:30PM | Duration 25h10 | Departure days Wed, Thu, Sat, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 01:10AM | Duration 32h35 | Departure days Thu | Cheapest price $171 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 11:30PM | Duration 30h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price $167 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 01:10AM | Duration 29h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 07:20AM | Duration 34h20 | Departure days Tue | Cheapest price $107 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 03:05AM | Duration 28h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20AM | Duration 32h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 07:20AM | Duration 31h45 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $108 |
Live departures
Rome to Brussels bus times
The table below shows live departures for Rome to Brussels buses for today, Thursday, February 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at 1:42 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 4788 · 50327 | 2:20 PM Roma, Autostazione Tiburtina | 25h10 | 3:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 3:35 PM Roma, Autostazione Tiburtina | 32h35 | 12:10 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 4:25 PM Roma, Autostazione (Metro Anagnina) | 30h05 | 10:30 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 28h20 | 2:05 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:55 PM Roma, Autostazione Tiburtina | 32h25 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:35 PM Roma, Autostazione (Metro Anagnina) | 31h45 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus | 11:10 PM Roma, Autostazione Tiburtina | 26h55 | 2:05 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| Friday, February 20 | |||||
| FlixBus · FlixBus · FlixBus | 6:45 AM Roma, Autostazione Tiburtina | 28h35 | 11:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus | 7:50 AM Roma, Autostazione Tiburtina | 27h55 | 11:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 8:35 AM Roma, Autostazione Tiburtina | 28h20 | 12:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:40 AM Roma, Autostazione Tiburtina | 31h15 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:10 AM Roma, Autostazione Tiburtina | 30h50 | 6:00 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 28h50 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 33h05 | 9:10 PM Brussels, Avenue des Magnolias (King Baudouin) | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Brussels buses with Omio?
FlixBus as well as BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus and more offer buses services from Rome to Brussels.
Omio is an official ticket reseller for all your travel options from Rome to Brussels.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus, Autoservizi Salemi Srl or Itabus to find the best option for your trip from Rome to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Brussels.
Why book with Omio over Wanderu, Checkmybus or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus, Autoservizi Salemi Srl or Itabus to find the best option for your trip from Rome to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Brussels.
Journey information
Overview: Bus from Rome to Brussels
Italy
Belgium
Buses from Rome to Brussels run on average 11 times per day, taking around 26h 32m. Cheap bus tickets for this journey start at $82 (€65) but you can travel from only $21 (€17) by flight.
The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 729 miles (1174 km) distance in 25h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Distance 729 miles (1174 km) |
Average bus duration 26h 32m |
Cheapest ticket price $82 (€65) |
Buses per day 11 |
Fastest bus 25h 10m |
First bus 00:10 |
Last bus 23:55 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Bus providers: FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus from Rome to BrusselsYou can travel by bus between Rome to Brussels with FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus for as low as $21 (€17). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
27h 30m
Cheapest Price
$82 (€65)
FlixBus frequency
12 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Itabus
About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
21h 40m
Cheapest Price
$113 (€90)
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
25h 10m
Cheapest Price
$104 (€83)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
Autoservizi Salemi Srl
Luggage & cancellation policy
Average Duration
26h 35m
Cheapest Price
$118 (€94)
Autoservizi Salemi Srl frequency
1 a day
FAQs: Bus from Rome to Brussels
Find answers to the most common questions about traveling from Rome to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Brussels can start from as little as $82 (€65) when you book in advance. The average bus ticket price for Rome to Brussels is $137 (€109) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Brussels is 25h 10m to travel the 729 miles (1174 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Brussels leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Brussels leaves at 11:55 PM.
There are 11 buses a day from Rome to Brussels which require at least one change with FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Rome to Brussels, you can count on FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus for the best way to get you to Brussels. You can also check all possible bus companies who offer a service between Rome and Brussels and compare the amenities they offer before buying a bus ticket.
A trip to Brussels from Rome is worth doing but not as a day trip with a journey time of 25h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Brussels is July.
It's helpful to compare your options as there are 3 ways to travel between Rome and Brussels including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Brussels:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Yes, there are bathrooms on board the bus from Rome to Brussels for bus company FlixBus, BlaBlaCar Bus, Itabus.
Some of the most interesting sights to explore in Brussels are:
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Whether you can cancel your bus ticket from Rome to Brussels depends on the bus companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, BlaBlaCar Bus, Itabus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Rome to Brussels:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Brussels:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Rome to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Rome to Brussels with the following bus company: FlixBus, BlaBlaCar Bus, Itabus
Yes, there are USB plugs on board the bus from Rome to Brussels with the following bus company: FlixBus, BlaBlaCar Bus, Itabus.
Yes, there is Wifi on board the bus from Rome to Brussels with the following bus company: FlixBus, BlaBlaCar Bus, Itabus.
popular bus stations
Popular bus stations from Rome to Brussels
Rome
Brussels
The major bus station for departures in Rome is Roma, Autostazione Tiburtina. Find all the information you need to know about services, amenities and connections at Roma, Autostazione Tiburtina for your trip from Rome to Brussels.
Roma, Autostazione Tiburtina
information
Roma, Autostazione (Metro Anagnina)
information
The major bus station for arrivals in Brussels is Brussels, Brussels South (Gare du Midi). Find all the information you need to know about services, amenities and connections at Brussels, Brussels South (Gare du Midi) for your trip to Brussels from Rome.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
2 km
Car connection
Avenue FonsnyWifi
- Free Wi-Fi
Dining
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels, Brussels South (Gare du Midi)
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:59
Distance to city center
1 kmCar connection
Rue du ProgrèsWifi
- Free Wi-Fi
Dining
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels-Noord
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Brussels, Gare Du Midi
information
More options for your journey from Rome to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Rome
Most popular bus connections to Brussels
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