- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Oct 04
$186
Average ticket price on Oct 04
$224
Fastest journey on Oct 04
1 d 4 h 20 m
Average journey duration on Oct 04
1 d 4 h 43 m
Buses on Oct 04
8
Distance
1174 km
The best way to find a cheap bus ticket from Rome to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Brussels will cost around $224 if you buy it on the day, but the cheapest tickets can be found for only $186.
It's difficult to get from Rome to Brussels without transferring at least 2 times.
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FlixBus · FlixBus · FlixBusBuses from Rome to Brussels run on average 10 times per day, taking around 25h 48m. Cheap bus tickets for this journey start at $54 (€45) but you can travel from only $21 (€18) by flight.
The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 729 miles (1174 km) distance in 23h 0m.
Distance 729 miles (1174 km) |
Average bus duration 25h 48m |
Cheapest ticket price $54 (€45) |
Buses per day 10 |
Fastest bus 23h 0m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 84 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 12:25PM | Duration 35h05 | Departure days Tue | Cheapest price $142 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 12:20PM | Duration 28h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $137 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 12:45PM | Duration 28h15 | Departure days Sat, Sun | Cheapest price $191 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 03:50PM | Duration 31h00 | Departure days Sat | Cheapest price $206 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 12:45PM | Duration 27h20 | Departure days Tue, Wed, Thu, Fri | Cheapest price $100 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 01:55PM | Duration 28h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 01:55PM | Duration 27h15 | Departure days Wed, Fri, Sat, Sun | Cheapest price $130 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 03:45PM | Duration 27h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $121 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 03:45PM | Duration 26h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $114 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 01:10AM | Duration 32h35 | Departure days Mon | Cheapest price $151 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 12:35AM | Duration 31h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 12:35AM | Duration 28h35 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $96 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 07:20AM | Duration 34h20 | Departure days Tue | Cheapest price $98 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 03:05AM | Duration 28h20 | Departure days Everyday | Cheapest price $96 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20AM | Duration 32h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $94 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 07:20AM | Duration 31h45 | Departure days Everyday | Cheapest price $106 |
The table below shows live departures for Rome to Brussels buses for today, Saturday, October 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 31h10 | 12:35 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 28h35 | 12:35 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 28h20 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 32h25 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 31h45 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:45 AM Roma, Autostazione Tiburtina | 28h35 | 12:20 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 29h10 | 1:40 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 28h25 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 29h05 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Rome to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Rome to Brussels buses use the Roma, Autostazione Tiburtina to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Rome and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
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