Pisa to Madrid bus with FlixBus

Sat, Dec 27
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FlixBus
Lirosi Linee
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Rede Expressos
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Lirosi Linee
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Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Pisa to Madrid

Showing times and prices for Jan 02

Cheapest price

$159

Average price

$207

Fastest journey

1 d 3 h 15 m

Average duration

1 d 9 h 53 m

Buses per day

3

Distance

1219 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Madrid will cost around $207 if you buy it on the day, but the cheapest tickets can be found for only $159.

Fast buses

It's difficult to get from Pisa to Madrid without transferring at least 2 times.

FlixBusFlixBus · FlixBus · FlixBus
06:25AM27h15
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
09:40AMMadrid, Estación Sur de Autobuses
$1591One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
10:00PM36h30
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
10:30AMMadrid, Estación Sur de Autobuses
$1761One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus · FlixBus
06:15PM37h55
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
08:10AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
$2851One-way
3 transfers

Travel Information

Compare train, bus, and flight for Pisa to Madrid

Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €76. For those with little time consider booking a flight which can get you there in 2h 58m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of €76, and a flight costs an average of €69.

Distance: 757 miles (1219 km)

Compare bus with

Bus
Most popular
Flight
Train

€144

Average price

Cheapest

€325

Average price

€278

Average price

23h 19m

Average total duration

22h 49m

Onboard

+

30m

Additional time*

5h 58m

Average total duration

Fastest

2h 58m

Onboard

+

3h 0m

Additional time*

29h 6m

Average total duration

28h 36m

Onboard

+

30m

Additional time*

1.2 - 3.0kg

CO2 emissions

Lowest

3.7 - 7.3kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Pisa to Madrid Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
05:45AM
Arrival Time
10:30AM
Duration
28h45
Departure days
Wed, Thu
Cheapest price
$107
Operator
FlixBus
Departure Time
06:25AM
Arrival Time
09:40AM
Duration
27h15
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$104
Operator
FlixBus
Departure Time
01:40PM
Arrival Time
08:10AM
Duration
42h30
Departure days
Mon
Cheapest price
$224
Operator
FlixBus
Departure Time
04:45PM
Arrival Time
08:20AM
Duration
39h35
Departure days
Wed, Thu, Sun
Cheapest price
$154
Operator
FlixBus
Departure Time
04:55PM
Arrival Time
10:30AM
Duration
41h35
Departure days
Wed
Cheapest price
$114
Operator
FlixBus
Departure Time
05:25PM
Arrival Time
10:30AM
Duration
41h05
Departure days
Thu
Cheapest price
$157
Operator
FlixBus
Departure Time
06:15PM
Arrival Time
08:10AM
Duration
37h55
Departure days
Fri, Sat
Cheapest price
$285
Operator
FlixBus
Departure Time
10:00PM
Arrival Time
10:30AM
Duration
36h30
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$112

Live departures

Pisa to Madrid bus times

The table below shows live departures for Pisa to Madrid buses for today, Thursday, January 1. You can also manually refresh the results below to see updated bus journeys.

Last updated at 2:53 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
40h20
8:05 AM Madrid, Estación Sur de Autobuses2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
39h35
7:20 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus4:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
41h05
9:30 AM Madrid, Estación Sur de Autobuses2 transfers
Friday, January 2
meinfernbus_flixbusFlixBus · FlixBus · FlixBus5:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
27h15
8:40 AM Madrid, Estación Sur de Autobuses2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Madrid by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Pisa to Madrid

ItalyItaly
SpainSpain
Icon of bus

Buses from Pisa to Madrid run on average 5 times per day, taking around 22h 49m. Cheap bus tickets for this journey start at $96 (€76) but you can travel from only $86 (€69) by flight.

The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 757 miles (1219 km) distance in 27h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $86 (€69)
Distance
757 miles (1219 km)
Average bus duration
22h 49m
Cheapest ticket price
$96 (€76)
Buses per day
5
Fastest bus
27h 15m
First bus
00:25
Last bus
23:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $86 (€69)

Bus providers: FlixBus, Lirosi Linee from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus, Lirosi Linee for as low as $86 (€69). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
28h 5m
Cheapest Price
$96 (€76)
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Lirosi Linee

Luggage & cancellation policy
Average Duration
27h 50m
Cheapest Price
$154 (€123)
Lirosi Linee frequency
1 a day

FAQs: Bus from Pisa to Madrid

Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Madrid can start from as little as $90 (€72) when you book in advance. The average bus ticket price for Pisa to Madrid is $183 (€146); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time from Pisa to Madrid is on average 25 h 50 min   for the 755 mile (1218 km) long journey, but the time it takes to go to Madrid from Pisa by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Pisa to Madrid leaves at 4: 45AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Pisa to Madrid leaves at 10: 30PM.
There are 3 buses a day from Pisa to Madrid which require at least one change with FlixBus or Lirosi Linee. Schedules can vary on holidays or weekends with fewer buses.
For the journey from Pisa to Madrid you can take a bus with FlixBus or Lirosi Linee. Be sure to check out all possible bus companies that offer services between Pisa and Madrid on Omio to compare what amenities they may have.
The cheapest month for a bus from Pisa to Madrid is February.
You have options as you can travel from Pisa to Madrid 3 different ways: train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Madrid:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Madrid for bus company FlixBus.
Some of the most interesting sights to explore in Madrid are:
  • Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
  • Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
  • Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
  • Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
  • Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
The best things to do in Madrid include:
  • Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
  • Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
  • Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
  • Attend a flamenco show to experience traditional Spanish dance and music
  • Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Pisa to Madrid depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Pisa to Madrid, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Pisa to Madrid.
    Yes, the following luggage options are included when booking a bus ticket from Pisa to Madrid:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Madrid:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Pisa to Madrid. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Pisa to Madrid with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Pisa to Madrid with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Pisa to Madrid with the following bus company: FlixBus.

    popular bus stations

    Popular bus stations from Pisa to Madrid

    Pisa
    Madrid
    The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Madrid.
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    Pisa, Aeroporto Parcheggio Aurelia
    information

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