The cheapest and fastest buses from Pisa to Madrid
Cheapest price
$196
Average price
$198
Fastest journey
1 d 4 h 45 m
Average duration
1 d 14 h 58 m
Buses per day
2
Distance
1219 km
The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Madrid will cost around $198 if you buy it on the day, but the cheapest tickets can be found for only $196.
It's difficult to get from Pisa to Madrid without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Pisa to Madrid
Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €76. For those with little time consider booking a flight which can get you there in 2h 58m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of €76, and a flight costs an average of €69.
Distance: 757 miles (1219 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€144 Average price Cheapest | €325 Average price | €278 Average price |
23h 19m Average total duration 22h 49m Onboard + 30m Additional time* | 5h 58m Average total duration Fastest 2h 58m Onboard + 3h 0m Additional time* | 29h 6m Average total duration 28h 36m Onboard + 30m Additional time* |
1.2 - 3.0kg CO2 emissions Lowest | 3.7 - 7.3kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Pisa to Madrid Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 10:30AM | Duration 28h45 | Departure days Tue | Cheapest price $196 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 10:30AM | Duration 28h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $145 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 08:20AM | Duration 49h10 | Departure days Tue, Wed | Cheapest price $199 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 09:05AM | Duration 40h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $125 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 10:30AM | Duration 41h35 | Departure days Wed | Cheapest price $179 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 10:30AM | Duration 36h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $143 |
Live departures
Pisa to Madrid bus times
The table below shows live departures for Pisa to Madrid buses for today, Monday, November 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 39h35 | 7:20 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 40h20 | 8:05 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 36h30 | 9:30 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
| Tuesday, November 18 | |||||
FlixBus · FlixBus | 4:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 28h45 | 9:30 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
FlixBus · FlixBus · FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 49h10 | 7:20 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 3 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Pisa to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 18
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Journey information
Overview: Bus from Pisa to Madrid
Buses from Pisa to Madrid run on average 5 times per day, taking around 22h 49m. Cheap bus tickets for this journey start at $94 (€76) but you can travel from only $85 (€69) by flight.
The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 757 miles (1219 km) distance in 27h 15m.
Distance 757 miles (1219 km) |
Average bus duration 22h 49m |
Cheapest ticket price $94 (€76) |
Buses per day 5 |
Fastest bus 27h 15m |
First bus 00:25 |
Last bus 23:45 |
Bus providers: FlixBus, Lirosi Linee from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus, Lirosi Linee for as low as $85 (€69). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Lirosi Linee
FAQs: Bus from Pisa to Madrid
Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
- Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
- Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
- Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
- Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
- Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
- Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
- Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
- Attend a flamenco show to experience traditional Spanish dance and music
- Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Pisa to Madrid, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
Most popular bus connections from Pisa
More options for your journey from Pisa to Madrid
Here are some other resources that might have the information you need
