- Must visit
Museo del Prado
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
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The cheapest and fastest buses from Pisa to Madrid
Showing times, prices and bookable tickets for Oct 01
Cheapest price on Oct 01
$157
Average ticket price on Oct 01
$183
Fastest journey on Oct 01
1 d 4 h 5 m
Average journey duration on Oct 01
1 d 11 h 19 m
Buses on Oct 01
8
Distance
1219 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Madrid will cost around $183 if you buy it on the day, but the cheapest tickets can be found for only $157.
Fast buses
It's difficult to get from Pisa to Madrid without transferring at least once.
FlixBus · FlixBus · FlixBus11:30 PM40h05Pisa (Pisamover via San Giusto/Aurelia)3:35 PMMadrid, Estación Sur de Autobuses$1571One-way2 transfers- FlixBus · FlixBus · FlixBus6:25 AM32h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1641One-way2 transfers
- FlixBus · FlixBus · FlixBus1:50 PM41h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:25 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1731One-way2 transfers
- FlixBus · FlixBus · FlixBus11:30 PM39h25Pisa (Pisamover via San Giusto/Aurelia)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1761One-way2 transfers
- FlixBus · FlixBus6:25 AM28h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:30 AMMadrid, Estación Sur de Autobuses$1861One-way1 transfer
- FlixBus · FlixBus6:25 AM28h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:30 AMMadrid, Estación Sur de Autobuses$1861One-way1 transfer
- FlixBus · FlixBus · FlixBus6:25 AM32h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1641One-way2 transfers
- FlixBus · FlixBus · FlixBus10:00 PM36h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:30 AMMadrid, Estación Sur de Autobuses$2021One-way2 transfers
- FlixBus · FlixBus · FlixBus11:30 PM39h25Pisa (Pisamover via San Giusto/Aurelia)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$1761One-way2 transfers
- FlixBus · FlixBus · FlixBus11:30 PM40h05Pisa (Pisamover via San Giusto/Aurelia)3:35 PMMadrid, Estación Sur de Autobuses$1571One-way2 transfers
Pisa to Madrid Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 10:30AM | Duration 28h45 | Departure days Mon, Tue | Cheapest price $126 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 10:30AM | Duration 28h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $137 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 07:25AM | Duration 43h25 | Departure days Mon, Thu | Cheapest price $179 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 07:25AM | Duration 41h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $173 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 08:10AM | Duration 39h25 | Departure days Mon, Sun | Cheapest price $156 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 02:55PM | Duration 45h30 | Departure days Mon | Cheapest price $205 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 02:55PM | Duration 44h45 | Departure days Wed | Cheapest price $158 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 02:55PM | Duration 40h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $137 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 02:55PM | Duration 39h25 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $112 |
Live departures
Pisa to Madrid bus times
The table below shows live departures for Pisa to Madrid buses for today, Wednesday, September 30. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus · FlixBus | 6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 44h45 | 2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 3 transfers | |
| FlixBus · FlixBus · FlixBus | 11:30 PM Pisa (Pisamover via San Giusto/Aurelia) | 40h05 | 3:35 PM Madrid, Estación Sur de Autobuses | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:30 PM Pisa (Pisamover via San Giusto/Aurelia) | 39h25 | 2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
| Thursday, October 1 | |||||
| FlixBus · FlixBus | 6:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 28h05 | 10:30 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 6:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 32h30 | 2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:00 PM Pisa (Pisamover via San Giusto/Aurelia) | 43h25 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 1:50 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 41h35 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa to Madrid buses with Omio?
FlixBus operates all buses services from Pisa to Madrid.
Omio is an official ticket reseller for all your travel options from Pisa to Madrid.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Madrid.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Madrid.
Journey information
Overview: Bus from Pisa to Madrid
Italy
Spain
Buses from Pisa to Madrid run on average 5 times per day, taking around 29h 29m. Cheap bus tickets for this journey start at $50 but you can travel from only $21 by flight.
The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 757 miles (1219 km) distance in 22h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21
Distance 757 miles (1219 km) |
Average bus duration 29h 29m |
Cheapest ticket price $50 |
Buses per day 5 |
Fastest bus 22h 35m |
First bus 12:25 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21
Bus providers: FlixBus from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus for as low as $21. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
22h 35m
Cheapest FlixBus Price
$50
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Madrid
Things to do in Madrid
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
- Must visit
Museo Nacional Centro de Arte Reina Sofía
Leading modern art museum best known for Picasso’s Guernica, plus major works by Dalí and Miró.
- Must visit
Museo Nacional Thyssen-Bornemisza
Celebrated collection of European masters from Van Eyck to Hopper in a refined palace setting.
- Must visit
El Retiro Park
Madrid’s most famous park offers gardens, a boating lake, monuments, and relaxed walks in the city center.
- Must visit
Gran Vía
Lively grand avenue known for architecture, shopping, theaters, and nonstop energy from day to night.
- Must visit
Paseo del Prado
Elegant boulevard linking major museums and landmarks, ideal for a classic central Madrid walk.
Cocido Madrileño
A hearty chickpea stew with meats, vegetables, and broth, especially traditional in Madrid and often served in stages.
Bocadillo de Calamares
Crisp fried squid rings served in a baguette roll. This iconic Madrid street food is especially linked to bars around Plaza Mayor.
- Gluten-free
Callos a la Madrileña
Tripe stew with chorizo and morcilla in a rich sauce. A classic old Madrid tavern dish with deep local roots.
DSTAgE
Refined two-Michelin-star dining focused on seasonal Spanish produce, with elegant modern cooking in a polished fine-dining room.
Malacatín
Traditional Madrid restaurant known for cocido madrileño served in stages, with an old-school dining room and loyal local following.
Sobrino de Botín
Historic century-old tavern famed for roast suckling pig and Castilian dishes in a classic, wood-lined setting near Plaza Mayor.
Euro (€)
Moderate for Western Europe: hotels vary, dining is reasonable, and public transport is good value for tourists.
Average meal costs
- Budget
- €8-12 for fast food or a simple menú.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person at upscale restaurants.
- Coffee
- €1.80-3.50 for coffee or cappuccino.
Tipping culture
Tipping is modest: round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, small change is enough.
Tarjeta Transporte
Get the appOfficial public transport app
Prices
- Single ticket
- €1.50
- Day pass
- €8.40
To the city center
Madrid Estación Sur de Autobuses -> Puerta del Sol
- Distance
- 4 km
- Travel time
- 20 min
- Contactless bank cards work on EMT Madrid city buses, but Metro usually requires a transport card or ticket.
- Buy the 10-trip ticket if you will make several journeys; it is valid on Metro zone A and EMT buses.
FAQs: Bus from Pisa to Madrid
Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Madrid can start from as little as $50 when you book in advance. The average bus ticket price for Pisa to Madrid is $175 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Madrid is 22h 35m to travel the 757 miles (1219 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Madrid leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Madrid leaves at 11:50 PM.
There are 5 buses a day from Pisa to Madrid which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Madrid, you can count on FlixBus for the best way to get you to Madrid. You can also check all possible bus companies who offer a service between Pisa and Madrid and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa (Pisamover via San Giusto/Aurelia) . When arriving in Madrid , you can end your journey in bus stations like Madrid, Estación Sur de Autobuses, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Madrid, Estación Sur de Autobuses, located 3 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Madrid including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Madrid:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Madrid for bus company FlixBus.
Whether you can cancel your bus ticket from Pisa to Madrid depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Madrid.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Madrid:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Madrid:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Madrid. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Madrid with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Madrid with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Madrid with the following bus company: FlixBus.
Spain uses the euro (€) as its currency. Travelers can use both cash and cards, but cards are widely accepted in cities and tourist areas, while cash may be preferred for small purchases, markets, and rural locations.
In Madrid, the main safety concerns for travelers include pickpocketing, especially in crowded areas like Puerta del Sol, Gran Vía, and on public transportation. Common scams involve distraction techniques, such as someone asking for signatures on petitions or offering friendship bracelets, to steal valuables. Travelers should also be cautious of unlicensed taxi drivers and always use official transport services. Staying vigilant in busy tourist spots and keeping belongings secure helps minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Madrid
Most Pisa to Madrid buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Madrid, Estación Sur de Autobuses station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Pisa and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Pisa
Arrival bus stations in Madrid
Which Pisa station do buses to Madrid leave from?
Buses from Pisa to Madrid leave from Pisa, Via delle Fiamme Gialle (Park Pietrasantina). The station is 1 miles (2 km) from Pisa city centre at Pisa Pietrasantina Parking, 56123 Pisa PI, Italy.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, 56123 Pisa PI, Italy
City-centre transport
Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Bus21, E24, 1+ · 12m · $1 · every ~10 min
1+, 21 · 14m · $1 · every ~9 min
1+ · 24m · $2 · every ~9 min
21 · 30m · $2
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) bus station facilities and services
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi and ATMs
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Tickets and information
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Parking, taxis and toilets
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Bike and car services
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia)Via S. Giusto, 56121 Pisa PI, Italy
City-centre transport
Getting to Pisa (Pisamover via San Giusto/Aurelia) from Pisa city centre
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Bus15 · 5m · $1 · every ~3 min
15 · 7m · $1 · every ~3 min
15 · 9m · $1 · every ~3 min
Pisa (Pisamover via San Giusto/Aurelia) bus station facilities and services
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Tickets and information
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Parking, taxis and toilets
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Which Madrid station do buses from Pisa arrive at?
Buses from Pisa to Madrid most often arrive at Madrid, Estación Sur de Autobuses. Some services arrive at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid), so check your ticket before travel to confirm your Madrid arrival station.
Madrid, Estación Sur de AutobusesCalle de Mendez Alvaro, 83, 28045 Madrid, Spain
City-centre transport
Getting to Madrid, Estación Sur de Autobuses from Madrid city centre
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
TrainC5, C10, C7 · 2m · $1 · every ~23 min
C10, C7 · 8m · $1 · every ~8 min
C3, C4, C4a, C4b · 11m · $1 · every ~15 min
BusN11 · 16m · $1 · every ~11 min
N13 · 18m · $1 · every ~15 min
148 · 45m · $5 · every ~30 min
Subway6 · 24m · $2 · every ~48 min
Madrid, Estación Sur de Autobuses bus station facilities and services
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Tickets and information
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Parking, taxis and toilets
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)Av. de la Hispanidad, s/n, 28042 Madrid, Spain
City-centre transport
Getting to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) from Madrid city centre
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Bus203, N27 · 1h 2m · $11 · every ~45 min
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) bus station facilities and services
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Rodilla, Mahoudrid
Wi-Fi and ATMs
ATMs are aTMs located throughout T4, major cards accepted .
Tickets and information
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Parking, taxis and toilets
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
More options for your journey from Pisa to Madrid
Here are some other resources that might have the information you need
Most popular buses to and from Madrid and Pisa
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