Pisa to Madrid bus with FlixBus

Mon, Aug 17
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2,000+ travel companies
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The cheapest and fastest buses from Pisa to Madrid

Showing times and prices for Aug 17

Cheapest price

$187

Average price

$226

Fastest journey

1 d 4 h 5 m

Average duration

1 d 11 h 55 m

Buses per day

5

Distance

1219 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Madrid will cost around $226 if you buy it on the day, but the cheapest tickets can be found for only $187.

Fast buses

It's difficult to get from Pisa to Madrid without transferring at least once.

  • FlixBusFlixBus · FlixBus
    6:25 AM28h05
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    10:30 AMMadrid, Estación Sur de Autobuses
    $1871One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    10:00 PM36h30
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    10:30 AMMadrid, Estación Sur de Autobuses
    $1881One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    6:25 AM32h30
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
    $2091One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    10:00 PM40h55
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
    $2461One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    1:50 PM41h35
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    7:25 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
    $2971One-way
    2 transfers

Travel Information

Compare train, bus, and flight for Pisa to Madrid

Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from $69. For those with little time consider booking a flight which can get you there in 3h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of $69, and a train costs an average of $260.

Distance: 757 miles (1219 km)

Compare bus with

Bus
Most popular
Flight
Train

$144

Average price

Cheapest

$239

Average price

$260

Average price

23h 19m

Average total duration

22h 49m

Onboard

+

30m

Additional time*

6h 38m

Average total duration

Fastest

3h 38m

Onboard

+

3h 0m

Additional time*

45h 53m

Average total duration

45h 23m

Onboard

+

30m

Additional time*

1.2 - 3.0kg

CO2 emissions

Lowest

3.7 - 7.3kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Pisa to Madrid is a bus with an average price of $144.

This is compared to other travel options from Pisa to Madrid:

A bus is $94 less than a flight for this route with tickets for a flight from Pisa to Madrid costing on average $239.

A bus is $116 less than a train for this route with tickets for a train from Pisa to Madrid costing on average $260.

The fastest way to travel from Pisa to Madrid is by flight with an average journey time of 3h 38m.

Other travel options to Madrid take longer:

Bus takes on average 22h 49m.

Train takes on average 45h 23m.

It's helpful to compare your options as there are 3 ways to travel between Pisa and Madrid including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Pisa to Madrid among Omio's users.

Pisa to Madrid Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
05:45AM
Arrival Time
10:30AM
Duration
28h45
Departure days
Tue, Wed
Cheapest price
$139
Operator
FlixBus
Departure Time
06:25AM
Arrival Time
02:55PM
Duration
32h30
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$137
Operator
FlixBus
Departure Time
09:40AM
Arrival Time
07:25AM
Duration
45h45
Departure days
Tue, Wed
Cheapest price
$249
Operator
FlixBus
Departure Time
01:50PM
Arrival Time
07:25AM
Duration
41h35
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$231
Operator
FlixBus
Departure Time
10:00PM
Arrival Time
10:30AM
Duration
36h30
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$153
Operator
FlixBus
Departure Time
11:30PM
Arrival Time
08:10AM
Duration
32h40
Departure days
Tue, Wed, Thu, Fri, Sat, Sun
Cheapest price
$130

Live departures

Pisa to Madrid bus times

The table below shows live departures for Pisa to Madrid buses for today, Sunday, August 16. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus · FlixBus6:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
32h30
2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)2 transfers
FlixBusFlixBus · FlixBus6:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
28h05
10:30 AM Madrid, Estación Sur de Autobuses1 transfer
FlixBusFlixBus · FlixBus · FlixBus1:50 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
41h35
7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
36h30
10:30 AM Madrid, Estación Sur de Autobuses2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
40h55
2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)2 transfers
FlixBusFlixBus · FlixBus · FlixBus · FlixBus11:30 PM Pisa (Pisamover via San Giusto/Aurelia)
32h40
8:10 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)3 transfers
FlixBusFlixBus · FlixBus · FlixBus11:30 PM Pisa (Pisamover via San Giusto/Aurelia)
40h05
3:35 PM Madrid, Estación Sur de Autobuses2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Madrid by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Pisa to Madrid buses with Omio?

FlixBus operates all buses services from Pisa to Madrid.
Omio is an official ticket reseller for all your travel options from Pisa to Madrid.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Madrid.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Madrid.

Journey information

Overview: Bus from Pisa to Madrid

ItalyItaly
SpainSpain
Icon of bus

Buses from Pisa to Madrid run on average 5 times per day, taking around 22h 49m. Cheap bus tickets for this journey start at $69 but you can travel from only $31 by flight.

The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 757 miles (1219 km) distance in 28h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31
Distance
757 miles (1219 km)
Average bus duration
22h 49m
Cheapest ticket price
$69
Buses per day
5
Fastest bus
28h 5m
First bus
12:25 AM
Last bus
11:50 PM
Cheapest Month
Oct
Cheapest Day
Wed
High Season
Oct - Dec
Low Season
Apr - Jun
Busiest Day
Wed
Least Busy Day
Fri
Best time to book
63 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31

Bus providers: FlixBus from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus for as low as $31. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
28h 5m
Cheapest Price
$69
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Madrid

Things to do in Madrid

Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.

  • Must visit

Museo del Prado

World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.

  • Must visit

Museo Nacional Centro de Arte Reina Sofía

Leading modern art museum best known for Picasso’s Guernica, plus major works by Dalí and Miró.

  • Must visit

Museo Nacional Thyssen-Bornemisza

Celebrated collection of European masters from Van Eyck to Hopper in a refined palace setting.

Euro (€)

Moderate for Western Europe: hotels vary, dining is reasonable, and public transport is good value for tourists.

Average meal costs

Budget
€8-12 for fast food or a simple menú.
Mid-range
€20-35 per person for a restaurant meal.
Fine dining
€60+ per person at upscale restaurants.
Coffee
€1.80-3.50 for coffee or cappuccino.

Tipping culture

Tipping is modest: round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, small change is enough.

FAQs: Bus from Pisa to Madrid

Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Madrid can start from as little as $69 when you book in advance. The average bus ticket price for Pisa to Madrid is $144 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Madrid is 28h 5m to travel the 757 miles (1219 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Madrid leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Madrid leaves at 11:50 PM.
There are 5 buses a day from Pisa to Madrid which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Madrid, you can count on FlixBus for the best way to get you to Madrid. You can also check all possible bus companies who offer a service between Pisa and Madrid and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa (Pisamover via San Giusto/Aurelia), Lucca, Viale Regina Margherita / Via Montanara . When arriving in Madrid , you can end your journey in bus stations like Madrid, Estación Sur de Autobuses, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Madrid, Estación Sur de Autobuses, located 3 away from the city centre.
A trip to Madrid from Pisa is worth doing but not as a day trip with a journey time of 28h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Madrid is October.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Madrid including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Madrid:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Madrid for bus company FlixBus.
Some of the most interesting sights to explore in Madrid are:
  • Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
  • Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
  • Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
  • Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
  • Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
The best things to do in Madrid include:
  • Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
  • Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
  • Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
  • Attend a flamenco show to experience traditional Spanish dance and music
  • Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
Whether you can cancel your bus ticket from Pisa to Madrid depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Madrid.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Madrid:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Madrid:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Madrid. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Madrid with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Madrid with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Madrid with the following bus company: FlixBus.
Since both Pisa and Madrid are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Pisa to Madrid among Omio's users.
Spain uses the euro (€) as its currency. Travelers can use both cash and cards, but cards are widely accepted in cities and tourist areas, while cash may be preferred for small purchases, markets, and rural locations.
In Madrid, the main safety concerns for travelers include pickpocketing, especially in crowded areas like Puerta del Sol, Gran Vía, and on public transportation. Common scams involve distraction techniques, such as someone asking for signatures on petitions or offering friendship bracelets, to steal valuables. Travelers should also be cautious of unlicensed taxi drivers and always use official transport services. Staying vigilant in busy tourist spots and keeping belongings secure helps minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Pisa to Madrid

Most Pisa to Madrid buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Madrid, Estación Sur de Autobuses station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Pisa and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Pisa
Arrival bus stations in Madrid

Which Pisa station do buses to Madrid leave from?

Buses from Pisa to Madrid leave from Pisa, Via delle Fiamme Gialle (Park Pietrasantina). The station is 1 miles (2 km) from Pisa city centre at Pisa Pietrasantina Parking, 56123 Pisa PI, Italy.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, 56123 Pisa PI, ItalyWifiParkingATMTaxisAccessibilityWCShowerTicket OfficeBike ParkingBike Rental
City-centre transport

Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre

Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:

Bus21, E24, 1+ · 12m · $1 · every ~10 min
1+, 21 · 14m · $1 · every ~9 min
1+ · 24m · $2 · every ~9 min
21 · 30m · $2

Pisa, Via delle Fiamme Gialle (Park Pietrasantina) bus station facilities and services

Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.

Wi-Fi and ATMs

Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).

Tickets and information

Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).

Parking, taxis and toilets

Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.

Bike and car services

Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.

Accessibility

Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.

Pisa (Pisamover via San Giusto/Aurelia)Via S. Giusto, 56121 Pisa PI, ItalyWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Pisa (Pisamover via San Giusto/Aurelia) from Pisa city centre

Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:

Bus15 · 5m · $1 · every ~3 min
15 · 7m · $1 · every ~3 min
15 · 9m · $1 · every ~3 min

Pisa (Pisamover via San Giusto/Aurelia) bus station facilities and services

Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).

Tickets and information

Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).

Parking, taxis and toilets

Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.

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