- Must visit
Städel Museum
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
Cheapest price on Sep 05
zł389
Average ticket price on Sep 05
zł489
Fastest journey on Sep 05
16 h 10 m
Average journey duration on Sep 05
17 h 33 m
Buses on Sep 05
12
Distance
723 km
The best way to find a cheap bus ticket from Pisa to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Frankfurt am Main will cost around zł489 if you buy it on the day, but the cheapest tickets can be found for only zł389.
It's difficult to get from Pisa to Frankfurt am Main without transferring at least once.
FlixBus · FlixBus+
FlixTrain
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus+
FlixTrainOmio recommends booking the flight as it is the most popular option from Pisa to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of zł398 For those with little time, consider booking a flight, which has an average total journey time of 3h 36m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.7 - 1.8kg. Average ticket prices depend on the travel mode: a bus costs an average of zł398, while a train costs an average of zł1132.
Distance: 449 miles (723 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
zł398 Average price Cheapest | zł976 Average price | zł1132 Average price | zł1084 Average price (fuel + tolls) |
16h 30m Average total duration 16h 0m Onboard + 30m Additional time* | 3h 36m Average total duration Fastest 1h 36m Onboard + 2h 0m Additional time* | 11h 27m Average total duration 10h 57m Onboard + 30m Additional time* | 10h 10m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Frankfurt am Main:
A bus is zł578 less than a flight for this route with tickets for a flight from Pisa to Frankfurt am Main costing on average zł976.
A bus is zł733 less than a train for this route with tickets for a train from Pisa to Frankfurt am Main costing on average zł1132.
Other travel options to Frankfurt am Main take longer:
Train takes on average 10h 57m.
Bus takes on average 16h 0m.
Tickets start at around zł398 compared to roughly zł1084 in fuel and tolls — a saving of about zł686. The journey takes 16h 0m versus 10h 10m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 02:50AM | Duration 22h05 | Departure days Sat | Cheapest price zł421 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 02:50AM | Duration 19h35 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price zł315 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 05:30AM | Duration 19h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price zł322 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 06:00AM | Duration 16h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price zł317 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 11:55AM | Duration 19h10 | Departure days Fri | Cheapest price zł510 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 03:55PM | Duration 22h45 | Departure days Everyday | Cheapest price zł285 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 04:40PM | Duration 22h30 | Departure days Wed, Fri, Sun | Cheapest price zł391 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 06:00PM | Duration 20h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price zł372 |
The table below shows live departures for Pisa to Frankfurt am Main buses for today, Friday, September 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+ FlixTrain | 4:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h10 | 11:55 AM Frankfurt South station | 2 transfers | |
FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h35 | 9:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h20 | 11:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h30 | 4:40 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h00 | 6:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h35 | 5:35 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
| Saturday, September 5 | |||||
FlixBus · FlixBus · FlixBus | 4:45 AM Pisa (Pisamover via San Giusto/Aurelia) | 22h05 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h35 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h00 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
FlixBus · FlixBus | 9:40 AM Pisa (Pisamover via San Giusto/Aurelia) | 20h10 | 5:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:40 AM Pisa (Pisamover via San Giusto/Aurelia) | 19h50 | 5:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 1:50 PM Pisa (Pisamover via San Giusto/Aurelia) | 16h10 | 6:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:50 PM Pisa (Pisamover via San Giusto/Aurelia) | 17h55 | 7:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pisa to Frankfurt am Main run on average 9 times per day, taking around 16h 0m. Cheap bus tickets for this journey start at zł260 if you book in advance.
The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 449 miles (723 km) distance in 16h 10m.
Distance 449 miles (723 km) |
Average bus duration 16h 0m |
Cheapest ticket price zł260 |
Buses per day 9 |
Fastest bus 16h 10m |
First bus 12:05 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Best time to book 14 days |
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
Museum in Goethe’s birthplace presenting the writer’s life, era, and manuscripts; essential for literary and cultural history fans.
Large natural history museum with dinosaur skeletons, biodiversity displays, and strong geology exhibits; excellent for all ages.
Rebuilt old town quarter between Römer and cathedral, blending historic layouts with new architecture; ideal for strolling and photos.
Frankfurt’s riverside museum district and promenade, perfect for walking, major museums, and skyline views across the Main.
Large inner-city palm garden with themed greenhouses and landscaped grounds; a relaxing break from museums and shopping.
Green sauce made with seven fresh herbs, usually served with boiled eggs and potatoes. It is a Frankfurt classic with protected regional status.
Pork sausage lightly smoked and traditionally served hot with potato salad, sauerkraut, or bread. It is one of Frankfurt’s signature sausages.
Pressed and cured pork sausage, often sliced and served cold with bread, mustard, and pickles. It is a staple in Frankfurt cider taverns.
Two Michelin-starred dining with creative modern cuisine, extensive wine pairings, and a formal fine dining experience.
Refined restaurant in the old opera house area, known for modern European cuisine, polished service, and an elegant dining room.
Historic apple wine tavern in Sachsenhausen known for Apfelwein, green sauce, and classic Frankfurt dishes in a lively traditional setting.
Moderate for Germany: hotels can be pricey during trade fairs, but dining and public transport are reasonable for most tourists.
Round up or tip about 5-10% in restaurants for good service. Taxis are usually rounded up. Small change is common for cafes.
Official public transport app
Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) -> Frankfurt (Main) Hauptbahnhof
Find answers to the most common questions about traveling from Pisa to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most Pisa to Frankfurt am Main buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) station pair, with some services arriving at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36). Use this guide to compare Pisa and Frankfurt am Main bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Here are some other resources that might have the information you need