Pisa to Frankfurt am Main bus with FlixBus

Fri, Dec 05
+ Add return
FlixBus
Lirosi Linee
Alsa
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Rede Expressos
1,000+ travel companies
FlixBus
Lirosi Linee
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Pisa to Frankfurt am Main

Showing times and prices for Dec 06

Cheapest price

$106

Average price

$120

Fastest journey

16 h 20 m

Average duration

19 h 16 m

Buses per day

5

Distance

723 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Frankfurt am Main will cost around $120 if you buy it on the day, but the cheapest tickets can be found for only $106.

Fast buses

Of the 5 buses that leave Pisa for Frankfurt am Main on Sat, Dec 06, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sat, Dec 06 the direct buses cover the 723 km distance in an average of 19 h 16 m but if you time it right, some buses will get you there in just 16 h 20 m .

On Sat, Dec 06 the slowest buses will take 23 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
11:40AM16h20
Pisa
04:00AMFrankfurt am Main
$1061One-way
0 transfers
FlixBus
09:30PM23h15
Pisa
08:45PMFrankfurt am Main
$1121One-way
0 transfers
FlixBus
02:45PM17h00
Pisa
07:45AMFrankfurt am Main
$1131One-way
0 transfers
FlixBus
07:40AM20h10
Pisa
03:50AMFrankfurt am Main
$1241One-way
0 transfers
FlixBus
04:15PM23h10
Pisa
03:25PMFrankfurt am Main
$1481One-way
0 transfers

Travel Information

Compare train, bus, and flight for Pisa to Frankfurt am Main

Omio recommends booking the flight as it is the most popular option from Pisa to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €56. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.8kg. The ticket price range depends on the travel mode: a bus costs an average of €56, and a flight costs an average of €134.

Distance: 449 miles (723 km)

Compare bus with

Bus
Most popular
Flight
Train

€100

Average price

Cheapest

€376

Average price

€250

Average price

16h 47m

Average total duration

16h 17m

Onboard

+

30m

Additional time*

5h 26m

Average total duration

Fastest

2h 26m

Onboard

+

3h 0m

Additional time*

12h 3m

Average total duration

11h 33m

Onboard

+

30m

Additional time*

0.7 - 1.8kg

CO2 emissions

Lowest

2.2 - 4.3kg

CO2 emissions

-

CO2 emissions

FlixBus

Most popular bus company

Air Dolomiti

Most popular airline

Trenitalia

Most popular train company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Pisa to Frankfurt am Main bus times

The table below shows live departures for Pisa to Frankfurt am Main buses for today, Friday, December 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 4:01 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus5:10 AM Pisa
19h40
12:50 AM Frankfurt am Main0 transfersDirect
meinfernbus_flixbus7:40 AM Pisa
19h50
3:30 AM Frankfurt am Main0 transfersDirect
meinfernbus_flixbus4:15 PM Pisa
23h10
3:25 PM Frankfurt am Main0 transfersDirect
meinfernbus_flixbus9:15 PM Pisa
23h30
8:45 PM Frankfurt am Main0 transfersDirect
meinfernbus_flixbus9:30 PM Pisa
23h15
8:45 PM Frankfurt am Main0 transfersDirect

Find all the dates and times for this journey

Compare prices and tickets Pisa to Frankfurt am Main by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Dec 06
Sun
Dec 07
Mon
Dec 08
Tue
Dec 09
Wed
Dec 10
Thu
Dec 11
Fri
Dec 12

Journey information

Overview: Bus from Pisa to Frankfurt am Main

ItalyItaly
GermanyGermany
Icon of bus

Buses from Pisa to Frankfurt am Main run on average 9 times per day, taking around 16h 17m. Cheap bus tickets for this journey start at $70 (€56) if you book in advance.

The earliest bus runs at 00:15, the last at 23:30. The fastest bus covers the 449 miles (723 km) distance in 16h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
449 miles (723 km)
Average bus duration
16h 17m
Cheapest ticket price
$70 (€56)
Buses per day
9
Fastest bus
16h 20m
First bus
00:15
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Lirosi Linee from Pisa to Frankfurt am MainYou can travel by bus between Pisa to Frankfurt am Main with FlixBus, Lirosi Linee for as low as $70 (€56). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 20m
Cheapest Price
$75 (€60)
FlixBus frequency
9 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Lirosi Linee

Luggage & cancellation policy
Average Duration
34h 25m
Cheapest Price
$84 (€68)
Lirosi Linee frequency
1 a day

FAQs: Bus from Pisa to Frankfurt am Main

Find answers to the most common questions about traveling from Pisa to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Pisa to Frankfurt am Main can start from as little as $66 (€53) when you book in advance. The average bus ticket price for Pisa to Frankfurt am Main is $104 (€84); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Pisa to Frankfurt am Main bus travel time is 17 h   for the 448 mile (723 km) long journey, but the duration can vary if you travel on weekends and holidays.
The first bus from Pisa to Frankfurt am Main leaves at 3: 50AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Pisa to Frankfurt am Main leaves at 7: 00PM.
There are 8 buses a day from Pisa to Frankfurt am Main which require at least one change with FlixBus or Lirosi Linee. Schedules can vary on holidays or weekends with fewer buses.
For the trip from Pisa to Frankfurt am Main you can take a bus with FlixBus or Lirosi Linee. Be sure to check out all possible bus companies that offer services between Pisa and Frankfurt am Main on Omio to compare what amenities they may have.
The cheapest month to travel from Pisa to Frankfurt am Main by bus is February.
You have options as you can travel to Frankfurt am Main from Pisa 3 different ways: train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Frankfurt am Main:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Frankfurt am Main for bus company FlixBus.
Some of the most interesting sights to explore in Frankfurt am Main are:
  • Römer, a historic city hall with medieval architecture located in the heart of Frankfurt's old town
  • Städel Museum, an art museum featuring a vast collection of European artworks from the Middle Ages to the present
  • Palmengarten, a large botanical garden showcasing diverse plant species in themed greenhouses and outdoor areas
  • Goethe House, the birthplace of the famous writer Johann Wolfgang von Goethe, now a museum dedicated to his life and works
  • Frankfurt Cathedral, a Gothic-style church with a rich history and stunning architecture.
The best things to do in Frankfurt am Main include:
  • Main Tower, a skyscraper with an observation deck providing panoramic views of the city
  • Explore the vibrant Kleinmarkthalle, an indoor market offering a variety of local and international foods
  • Visit the Senckenberg Natural History Museum, home to an extensive collection of dinosaur fossils and natural exhibits
  • Take a leisurely walk along the River Main and enjoy the scenic views
  • Experience the lively atmosphere of the Zeil, Frankfurt's premier shopping street.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Pisa to Frankfurt am Main depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Pisa to Frankfurt am Main, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Pisa to Frankfurt am Main.
    Yes, the following luggage options are included when booking a bus ticket from Pisa to Frankfurt am Main:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Frankfurt am Main:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Pisa to Frankfurt am Main. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Pisa to Frankfurt am Main with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Pisa to Frankfurt am Main with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Pisa to Frankfurt am Main with the following bus company: FlixBus.

    popular bus stations

    Popular bus stations from Pisa to Frankfurt am Main

    Pisa
    Frankfurt am Main
    The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Frankfurt am Main.
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    Pisa, Aeroporto Parcheggio Aurelia
    information

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