- Must visit
Städel Museum
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
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The cheapest and fastest buses from Pisa to Frankfurt am Main
Showing times, prices and bookable tickets for Oct 20
Cheapest price on Oct 20
€71
Average ticket price on Oct 20
€73
Fastest journey on Oct 20
16 h 35 m
Average journey duration on Oct 20
19 h 27 m
Buses on Oct 20
5
Distance
723 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Frankfurt am Main will cost around €73 if you buy it on the day, but the cheapest tickets can be found for only €71.
Fast buses
It's difficult to get from Pisa to Frankfurt am Main without transferring at least once.
FlixBus · FlixBus · FlixBus7:15 AM19h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:50 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€711One-way2 transfers- FlixBus · FlixBus5:10 PM18h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:30 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€721One-way1 transfer
- FlixBus · FlixBus+
FlixTrain5:10 PM22h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:55 PMFrankfurt South station€721One-way2 transfers - FlixBus · FlixBus5:10 PM16h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:45 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€731One-way1 transfer
- FlixBus · FlixBus · FlixBus7:15 AM20h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€741One-way2 transfers
- FlixBus · FlixBus5:10 PM16h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:45 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€731One-way1 transfer
- FlixBus · FlixBus5:10 PM18h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:30 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€721One-way1 transfer
- FlixBus · FlixBus · FlixBus7:15 AM19h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:50 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€711One-way2 transfers
- FlixBus · FlixBus · FlixBus7:15 AM20h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€741One-way2 transfers
- FlixBus · FlixBus+FlixTrain5:10 PM22h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:55 PMFrankfurt South station€721One-way2 transfers
Journey information
Overview: Bus from Pisa to Frankfurt am Main
Italy
Germany
Buses from Pisa to Frankfurt am Main run on average 8 times per day, taking around 16h 29m. Cheap bus tickets for this journey start at €54 if you book in advance.
The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 449 miles (723 km) distance in 13h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 449 miles (723 km) |
Average bus duration 16h 29m |
Cheapest ticket price €54 |
Buses per day 8 |
Fastest bus 13h 25m |
First bus 12:05 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Pisa to Frankfurt am Main Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 02:50AM | Duration 22h05 | Departure days Sun | Cheapest price €74 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 02:50AM | Duration 19h35 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €71 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 05:30AM | Duration 19h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €75 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 07:45AM | Duration 17h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €73 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 01:55PM | Duration 21h10 | Departure days Fri, Sat | Cheapest price €93 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 09:45AM | Duration 16h35 | Departure days Everyday | Cheapest price €71 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 04:40PM | Duration 22h30 | Departure days Thu | Cheapest price €84 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:35PM | Duration 19h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €83 |
Live departures
Pisa to Frankfurt am Main bus times
The table below shows live departures for Pisa to Frankfurt am Main buses for today, Monday, October 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h35 | 9:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
| FlixBus · FlixBus+FlixTrain | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h45 | 3:55 PM Frankfurt South station | 2 transfers | |
| FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h20 | 11:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h00 | 6:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h35 | 5:35 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h35 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h00 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Pisa to Frankfurt am Main buses with Omio?
FlixBus operates all buses services from Pisa to Frankfurt am Main.
Omio is an official ticket reseller for all your travel options from Pisa to Frankfurt am Main.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Frankfurt am Main.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Frankfurt am Main.
Bus providers: FlixBus from Pisa to Frankfurt am MainYou can travel by bus between Pisa to Frankfurt am Main with FlixBus for as low as €54. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
13h 25m
Cheapest FlixBus Price
€54
FlixBus frequency
8 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Frankfurt am Main
Things to do in Frankfurt am Main
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
- Must visit
Goethe-Haus und Goethe-Museum
Museum in Goethe’s birthplace presenting the writer’s life, era, and manuscripts; essential for literary and cultural history fans.
- Must visit
Senckenberg Naturmuseum
Large natural history museum with dinosaur skeletons, biodiversity displays, and strong geology exhibits; excellent for all ages.
- Must visit
Neue Altstadt
Rebuilt old town quarter between Römer and cathedral, blending historic layouts with new architecture; ideal for strolling and photos.
- Must visit
Museumsufer
Frankfurt’s riverside museum district and promenade, perfect for walking, major museums, and skyline views across the Main.
- Must visit
Palmengarten
Large inner-city palm garden with themed greenhouses and landscaped grounds; a relaxing break from museums and shopping.
- Vegetarian
- Gluten-free
Frankfurter Grüne Soße
Green sauce made with seven fresh herbs, usually served with boiled eggs and potatoes. It is a Frankfurt classic with protected regional status.
Frankfurter Würstchen
Pork sausage lightly smoked and traditionally served hot with potato salad, sauerkraut, or bread. It is one of Frankfurt’s signature sausages.
Frankfurter Rindswurst
Pressed and cured pork sausage, often sliced and served cold with bread, mustard, and pickles. It is a staple in Frankfurt cider taverns.
Lafleur
Two Michelin-starred dining with creative modern cuisine, extensive wine pairings, and a formal fine dining experience.
Restaurant Opéra
Refined restaurant in the old opera house area, known for modern European cuisine, polished service, and an elegant dining room.
Apfelwein Wagner
Historic apple wine tavern in Sachsenhausen known for Apfelwein, green sauce, and classic Frankfurt dishes in a lively traditional setting.
Euro (€)
Moderate for Germany: hotels can be pricey during trade fairs, but dining and public transport are reasonable for most tourists.
Average meal costs
- Budget
- €8-12 for fast food or simple takeaway.
- Mid-range
- €18-30 per person for a casual restaurant meal.
- Fine dining
- €70+ per person for upscale dining.
- Coffee
- €3-4.50 for a cappuccino.
Tipping culture
Round up or tip about 5-10% in restaurants for good service. Taxis are usually rounded up. Small change is common for cafes.
RMVgo
Get the appOfficial public transport app
Prices
- Single ticket
- €3.80
- Day pass
- €12.00
To the city center
Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) -> Frankfurt (Main) Hauptbahnhof
- Distance
- 12 km
- Travel time
- 25 min
- Buy tickets in the RMVgo app or at station machines before boarding. Frankfurt buses, trams, and U-Bahn do not generally support onboard contactless bank card payment.
- A day pass can be good value for 4 or more trips within Frankfurt fare zone 5000. Validate paper tickets only if your ticket shows that validation is required.
FAQs: Bus from Pisa to Frankfurt am Main
Find answers to the most common questions about traveling from Pisa to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Frankfurt am Main can start from as little as €54 when you book in advance. The average bus ticket price for Pisa to Frankfurt am Main is €105 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Frankfurt am Main is 13h 25m to travel the 449 miles (723 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Frankfurt am Main leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Frankfurt am Main leaves at 11:30 PM.
There are 8 buses a day from Pisa to Frankfurt am Main which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Frankfurt am Main, you can count on FlixBus for the best way to get you to Frankfurt am Main. You can also check all possible bus companies who offer a service between Pisa and Frankfurt am Main and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Frankfurt am Main including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Frankfurt am Main:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Frankfurt am Main for bus company FlixBus.
Whether you can cancel your bus ticket from Pisa to Frankfurt am Main depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Frankfurt am Main.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Frankfurt am Main:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Frankfurt am Main:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Frankfurt am Main. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Frankfurt am Main with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Frankfurt am Main with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Frankfurt am Main with the following bus company: FlixBus.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
In Frankfurt am Main, travelers should be cautious of pickpocketing, especially in crowded areas like train stations, public transport, and popular tourist spots. Common scams include distraction techniques where one person diverts attention while another steals belongings. It's also important to be wary of unofficial taxi drivers overcharging and to use licensed services. Staying alert in nightlife districts and avoiding poorly lit areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Frankfurt am Main
Most Pisa to Frankfurt am Main buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) station pair, with some services arriving at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36). Use this guide to compare Pisa and Frankfurt am Main bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Pisa
Arrival bus stations in Frankfurt am Main
Which Pisa station do buses to Frankfurt am Main leave from?
Buses from Pisa to Frankfurt am Main leave from Pisa, Via delle Fiamme Gialle (Park Pietrasantina). The station is 1 miles (2 km) from Pisa city centre at Pisa Pietrasantina Parking, 56123 Pisa PI, Italy.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, 56123 Pisa PI, Italy
City-centre transport
Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Bus21, E24, 1+ · 12m · €1 · every ~10 min
1+, 21 · 14m · €1 · every ~9 min
1+ · 24m · €2 · every ~9 min
21 · 30m · €2
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) bus station facilities and services
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi and ATMs
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Tickets and information
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Parking, taxis and toilets
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Bike and car services
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia)Via S. Giusto, 56121 Pisa PI, Italy
City-centre transport
Getting to Pisa (Pisamover via San Giusto/Aurelia) from Pisa city centre
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Bus15 · 5m · €1 · every ~3 min
15 · 7m · €1 · every ~3 min
15 · 9m · €1 · every ~3 min
Pisa (Pisamover via San Giusto/Aurelia) bus station facilities and services
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Tickets and information
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Parking, taxis and toilets
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
City-centre transport
Getting to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) from Frankfurt am Main city centre
Tram12 · 10m · €3 · every ~13 min
12 · 14m · €3 · every ~13 min
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
City-centre transport
Getting to Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) from Frankfurt am Main city centre
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
TrainIce · 19m · €2
S9, S8 · 24m · €3 · every ~9 min
BusBlaBlaCar Bus · 15m · €1 · every ~1 min
: Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station, RegioJet 540 · 30m · €1
X61, 61 · 35m · every ~13 min
61, X61 · 36m · every ~13 min
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) bus station facilities and services
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: McDonald's (in the station), Hausmann's (in the station).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Tickets and information
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Parking, taxis and toilets
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
More options for your journey from Pisa to Frankfurt am Main
Here are some other resources that might have the information you need
Most popular buses to and from Frankfurt am Main and Pisa
Most popular bus connections to Frankfurt am Main
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