- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.


Cheapest price
$161
Average price
$161
Fastest journey
20h 45m
Average duration
20h 55m
Buses per day
2
Distance
320 km
Omio recommends booking the flight as it is the most popular option from Manchester to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $28. For those with little time consider booking a flight which can get you there in 2h 3m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.5 - 1.3kg. The ticket price range depends on the travel mode: a flight costs an average of $28, and a train costs an average of $399.
Distance: 333 miles (536 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$122 Average price | $121 Average price Cheapest | $399 Average price | $110 Average price (fuel + tolls) |
15h 39m Average total duration 15h 9m Onboard + 30m Additional time* | 5h 3m Average total duration Fastest 2h 3m Onboard + 3h 0m Additional time* | 6h 48m Average total duration 6h 18m Onboard + 30m Additional time* | 8h 18m Average total duration (door-to-door) |
0.5 - 1.3kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Manchester to Brussels:
A flight is $0.41 (€0.34) less than a bus for this route with tickets for a bus from Manchester to Brussels costing on average $122 (€100).
A flight is $278 (€228) less than a train for this route with tickets for a train from Manchester to Brussels costing on average $399 (€328).
Other travel options to Brussels take longer:
Train takes on average 6h 18m.
Bus takes on average 15h 9m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 06:20PM | Duration 17h00 | Departure days Tue | Cheapest price $210 |
Operator FlixBus | Departure Time 02:50AM | Arrival Time 12:35AM | Duration 20h45 | Departure days Sat, Sun | Cheapest price $161 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 05:55AM | Duration 15h05 | Departure days Tue, Thu, Fri | Cheapest price $141 |
Operator FlixBus | Departure Time 02:10PM | Arrival Time 05:55AM | Duration 14h45 | Departure days Tue, Thu, Fri | Cheapest price $140 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 09:20AM | Duration 16h50 | Departure days Tue | Cheapest price $128 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 03:45PM | Duration 21h05 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $155 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 03:45PM | Duration 20h45 | Departure days Mon, Wed, Sat | Cheapest price $155 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 03:45PM | Duration 20h40 | Departure days Fri, Sun | Cheapest price $186 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 06:20PM | Duration 17h21 | Departure days Tue | Cheapest price $148 |
The table below shows live departures for Manchester to Brussels buses for today, Wednesday, July 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:40 PM Manchester, Shudehill Interchange | 21h05 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:00 PM Manchester, Princess Road / Moss Lane East | 20h45 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Manchester to Brussels run on average 5 times per day, taking around 15h 9m. Cheap bus tickets for this journey start at $78 (€64) but you can travel from only $28 (€23) by flight.
The earliest bus runs at 00:05, the last at 23:40. The fastest bus covers the 333 miles (536 km) distance in 14h 5m.
Distance 333 miles (536 km) |
Average bus duration 15h 9m |
Cheapest ticket price $78 (€64) |
Buses per day 5 |
Fastest bus 14h 5m |
First bus 12:05 AM |
Last bus 11:40 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Fri |
Best time to book 28 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Manchester to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Manchester to Brussels buses use the Manchester, Shudehill Interchange to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussels, Gare Du Midi. Use this guide to compare Manchester and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Manchester, Shudehill Interchange has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Manchester, Shudehill Interchange.
Available at Manchester, Shudehill Interchange: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Shudehill Interchange: Elevators, ramps.
Manchester, Airport is 2 km from Manchester city centre. Public transport options include:
Manchester, Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Burger King (in the station), Giraffe (in the station).
Free Wi-Fi. ATMs are located throughout the airport, offering multiple currency options.
Ticket office support is available at Manchester, Airport.
Available at Manchester, Airport: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Airport: Elevators, ramps, assistance.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
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