The cheapest and fastest buses from Madrid to Brussels
Cheapest price
$63
Average price
$114
Fastest journey
20 h 30 m
Average duration
20 h 51 m
Buses per day
8
Distance
1316 km
The best way to find a cheap bus ticket from Madrid to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Brussels will cost around $114 if you buy it on the day, but the cheapest tickets can be found for only $63.
It's difficult to get from Madrid to Brussels without transferring at least once.
3162 · 50321
3160 · 50100
4004 · 1657
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FlixBus · FlixBus
4004 · 1657
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3162 · 50321
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Madrid to Brussels
Omio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $48. For those with little time consider booking a flight which can get you there in 2h 59m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.3kg. The ticket price range depends on the travel mode: a bus costs an average of $48, and a train costs an average of $459.
Distance: 817 miles (1316 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$92 Average price Cheapest | $205 Average price | $471 Average price |
22h 0m Average total duration 21h 30m Onboard + 30m Additional time* | 5h 59m Average total duration Fastest 2h 59m Onboard + 3h 0m Additional time* | 15h 45m Average total duration 15h 15m Onboard + 30m Additional time* |
1.3 - 3.3kg CO2 emissions Lowest | 3.9 - 7.9kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Madrid to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:50PM | Arrival Time 12:45PM | Duration 21h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $89 |
Operator Infobus | Departure Time 03:30PM | Arrival Time 12:00PM | Duration 20h30 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $77 |
Operator BlaBlaCar Bus | Departure Time 03:30PM | Arrival Time 12:00PM | Duration 20h30 | Departure days Everyday | Cheapest price $73 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 03:50PM | Duration 23h55 | Departure days Tue, Thu, Sat | Cheapest price $116 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 03:35PM | Duration 22h55 | Departure days Tue, Wed, Thu, Fri, Sun | Cheapest price $102 |
Operator BlaBlaCar Bus | Departure Time 06:35PM | Arrival Time 03:15PM | Duration 20h40 | Departure days Everyday | Cheapest price $63 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 05:55PM | Duration 21h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $94 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 05:55PM | Duration 21h05 | Departure days Everyday | Cheapest price $109 |
Operator BlaBlaCar Bus | Departure Time 10:30PM | Arrival Time 08:50PM | Duration 22h20 | Departure days Everyday | Cheapest price $72 |
Live departures
Madrid to Brussels bus times
The table below shows live departures for Madrid to Brussels buses for today, Tuesday, March 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 1:50 PM Madrid, Estación Sur de Autobuses | 21h55 | 11:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
4004 · 1657 | 2:30 PM Madrid, Estación Sur de Autobuses | 20h30 | 11:00 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 2:55 PM Madrid, Estación Sur de Autobuses | 23h55 | 2:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:55 PM Madrid, Estación Sur de Autobuses | 23h40 | 2:35 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 2:55 PM Madrid, Estación Sur de Autobuses | 26h00 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 3:40 PM Madrid, Estación Sur de Autobuses | 22h55 | 2:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Madrid, Estación Sur de Autobuses | 23h10 | 2:50 PM Brussels, Gare Du Midi | 1 transfer | |
3162 · 1433 | 5:35 PM Madrid, Estación Sur de Autobuses | 22h55 | 4:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 7:25 PM Madrid, Estación Sur de Autobuses | 21h30 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 7:50 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 21h05 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
3160 · 50100 | 9:30 PM Madrid, Estación Sur de Autobuses | 22h20 | 7:50 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Madrid to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
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Mar 18
Mar 19
Mar 20
Mar 21
Mar 22
Mar 23
Why should you book Madrid to Brussels buses with Omio?
Why book with Omio vs BlaBlaCar Bus?
- Compare with other providers: On Omio, you can not only buy tickets for BlaBlaCar Bus, but also compare tickets for the likes of FlixBus, Alsa, Infobus or Empresa Municipal de Transportes to find the best option for your trip from Madrid to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare BlaBlaCar Bus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Madrid to Brussels.
Why book with Omio over Checkmybus, Wanderu or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, Alsa, Infobus or Empresa Municipal de Transportes to find the best option for your trip from Madrid to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Madrid to Brussels.
Journey information
Overview: Bus from Madrid to Brussels
Buses from Madrid to Brussels run on average 10 times per day, taking around 21h 30m. Cheap bus tickets for this journey start at $48 (€38) but you can travel from only $34 (€28) by flight.
The earliest bus runs at 00:40, the last at 23:50. The fastest bus covers the 817 miles (1316 km) distance in 20h 30m.
Distance 817 miles (1316 km) |
Average bus duration 21h 30m |
Cheapest ticket price $48 (€38) |
Buses per day 10 |
Fastest bus 20h 30m |
First bus 00:40 |
Last bus 23:50 |
Bus providers: BlaBlaCar Bus, FlixBus, Alsa, Infobus, Empresa Municipal de Transportes from Madrid to BrusselsYou can travel by bus between Madrid to Brussels with BlaBlaCar Bus, FlixBus, Alsa, Infobus, Empresa Municipal de Transportes for as low as $34 (€28). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Alsa
Infobus
BlaBlaCar Bus
Empresa Municipal de Transportes
FAQs: Bus from Madrid to Brussels
Find answers to the most common questions about traveling from Madrid to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Madrid to Brussels
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
- 06:00-23:00
- Rodilla, Mahoudrid
- Step-free access, elevators, accessible toilets
- Located inside the terminal, well-signposted, accessible, and generally clean
- No public showers in the bus station area; showers available in airport lounges (approx. €15-€30 for lounge access)
- Metro Line 8, Aeropuerto T4, 12 km
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
More options for your journey from Madrid to Brussels
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