- Must visit
Royal Museums of Fine Arts of Belgium
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Cheapest price
$73
Average price
$135
Fastest journey
20 h 30 m
Average duration
21 h 28 m
Buses per day
13
Distance
1316 km
The best way to find a cheap bus ticket from Madrid to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Brussels will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $73.
It's difficult to get from Madrid to Brussels without transferring at least once.
3162 · 1433
3160 · 50100
4004 · 1657
FlixBus · FlixBus
FlixBus · FlixBus
4004 · 1657
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
3160 · 50100Omio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a flight which can get you there in 4h 4m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.3kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a train costs an average of $502.
Distance: 817 miles (1316 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$103 Average price Cheapest | $280 Average price | $508 Average price | $316 Average price (fuel + tolls) |
18h 8m Average total duration 17h 38m Onboard + 30m Additional time* | 7h 4m Average total duration Fastest 4h 4m Onboard + 3h 0m Additional time* | 21h 13m Average total duration 20h 43m Onboard + 30m Additional time* | 16h 17m Average total duration (door-to-door) |
1.3 - 3.3kg CO2 emissions Lowest | 3.9 - 7.9kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Brussels:
A bus is $176 (€143) less than a flight for this route with tickets for a flight from Madrid to Brussels costing on average $280 (€226).
A bus is $405 (€327) less than a train for this route with tickets for a train from Madrid to Brussels costing on average $508 (€411).
Other travel options to Brussels take longer:
Bus takes on average 17h 38m.
Train takes on average 20h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:50PM | Arrival Time 01:40PM | Duration 22h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $125 |
Operator BlaBlaCar Bus | Departure Time 03:30PM | Arrival Time 12:00PM | Duration 20h30 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator Internorte | Departure Time 03:30PM | Arrival Time 02:10PM | Duration 22h40 | Departure days Wed, Fri, Sun | Cheapest price $67 |
Operator Alsa | Departure Time 03:30PM | Arrival Time 02:10PM | Duration 22h40 | Departure days Wed, Fri, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 03:35PM | Duration 23h40 | Departure days Tue, Thu, Sat | Cheapest price $107 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 10:10PM | Duration 29h30 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $116 |
Operator BlaBlaCar Bus | Departure Time 06:35PM | Arrival Time 05:30PM | Duration 22h55 | Departure days Everyday | Cheapest price $62 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 05:55PM | Duration 21h30 | Departure days Everyday | Cheapest price $112 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 05:55PM | Duration 21h05 | Departure days Everyday | Cheapest price $120 |
Operator BlaBlaCar Bus | Departure Time 10:30PM | Arrival Time 08:50PM | Duration 22h20 | Departure days Everyday | Cheapest price $67 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 01:10AM | Duration 26h35 | Departure days Everyday | Cheapest price $111 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 01:10AM | Duration 26h15 | Departure days Everyday | Cheapest price $119 |
The table below shows live departures for Madrid to Brussels buses for today, Monday, June 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:25 PM Madrid, Estación Sur de Autobuses | 21h30 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 8:50 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 21h05 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
3160 · 50100 | 10:30 PM Madrid, Estación Sur de Autobuses | 22h20 | 8:50 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 10:35 PM Madrid, Estación Sur de Autobuses | 26h35 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 10:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 26h15 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 2:50 PM Madrid, Estación Sur de Autobuses | 21h55 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
4004 · 1657 | 3:30 PM Madrid, Estación Sur de Autobuses | 20h30 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h40 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h55 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 26h00 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 23h10 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 22h55 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
3162 · 1433 | 6:35 PM Madrid, Estación Sur de Autobuses | 22h55 | 5:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Madrid to Brussels run on average 10 times per day, taking around 17h 38m. Cheap bus tickets for this journey start at $57 (€46) if you book in advance.
The earliest bus runs at 00:40, the last at 23:55. The fastest bus covers the 817 miles (1316 km) distance in 20h 30m.
Distance 817 miles (1316 km) |
Average bus duration 17h 38m |
Cheapest ticket price $57 (€46) |
Buses per day 10 |
Fastest bus 20h 30m |
First bus 12:40 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 21 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Dedicated to René Magritte, this museum holds the world's largest collection of his works. It is a standout stop for surrealism lovers and one of Brussels' most famous museums.
A contemporary art museum known for street art, digital culture, and youth-oriented exhibitions. It became especially popular with younger visitors and on social media.
A landscaped cultural hill linking the upper and lower city, known for its formal gardens and classic skyline view. It is one of Brussels' best walking and photography spots.
A beautiful 19th-century covered arcade with elegant glass roofing and historic atmosphere. It is one of the city's most photogenic and fashionable passages.
A grand urban park laid out around monumental buildings and the Cinquantenaire Arch. Ideal for a walk, photos, and combining with nearby museums.
Brussels’ classic pairing of mussels steamed with white wine, celery, and herbs, served with crisp fries. It is one of the city’s most iconic and widely loved meals.
A traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. It is a staple of local brasserie cuisine.
A comforting Brussels side dish of mashed potatoes mixed with seasonal vegetables such as carrots, leeks, or spinach, often served with sausage or meat.
Well-regarded Belgian restaurant serving regional classics, strong beer pairings, and seasonal ingredients in a cozy, old-Brussels dining room.
One of Brussels’ landmark fine-dining restaurants, celebrated for refined Belgian-influenced cuisine, polished service, and an elegant Art Nouveau setting.
Popular traditional restaurant near Sainte-Catherine known for generous Belgian comfort food, beer-based stews, and an unfussy, bustling atmosphere.
Moderate by Western European standards. Beer, waffles, and transit are reasonable; hotels and central dining cost more.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Round up taxi fares.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station
Find answers to the most common questions about traveling from Madrid to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need