Travel Information
Compare bus and train for Karlsruhe to Brussels
Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $27. For those with little time consider booking a train which can get you there in 3h 37m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $27, and a train costs an average of $40.
Distance: 219 miles (354 km)
Compare train with
Most popular Train | Bus |
|---|---|
$132 Average price | $51 Average price Cheapest |
4h 7m Average total duration Fastest 3h 37m Onboard + 30m Additional time* | 8h 5m Average total duration 7h 35m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Karlsruhe to Brussels
How to get from Karlsruhe to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Brussels is by taking a bus because it’s the best combination of price and speed.
51510 · 47439:05 PM7h50Karlsruhe, Hinterm Hauptbahnhof (Südeingang)4:55 AMBrussels, Brussels South (Gare du Midi)$591One-way1 transfer
Cheapest
51510 · 47439:05 PM7h50Karlsruhe, Hinterm Hauptbahnhof (Südeingang)4:55 AMBrussels, Brussels South (Gare du Midi)$591One-way1 transfer
Fastest
202 · 168:59 AM4h27Karlsruhe Hbf1:26 PMBrussels-North$1991One-way1 transfer
Other options
202 · 168:59 AM4h36Karlsruhe Hbf1:35 PMBrussels-Midi$1991One-way1 transfer
ICE 202 · ICE 168:59 AM4h36Karlsruhe Hbf1:35 PMBrussels-Midi$1991One-way1 transfer
202 · 16+
39848:59 AM4h35Karlsruhe Hbf1:34 PMBrussels-Central$2031One-way2 transfers
FlixBus · FlixBus4:35 PM10h50Karlsruhe Hbf3:25 AMBrussels, Brussels South (Gare du Midi)$681One-way1 transfer
ICE 202+
KL1820 · KL17078:59 AM13h16Karlsruhe Hbf10:15 PMBrussels Airport$4871One-way2 transfers
ICE 76 · ICE 1014+
KL1820 · KL17076:37 AM15h38Karlsruhe Hbf10:15 PMBrussels Airport$4721One-way3 transfers
ECE 8 · ICE 1012+
KL1820 · KL17078:37 AM13h38Karlsruhe Hbf10:15 PMBrussels Airport$4921One-way3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Karlsruhe to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Brussels.

This is compared to other travel options from Karlsruhe to Brussels:
A bus is $13 (€11) less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $40 (€32).
Other travel options to Brussels take longer:
Bus takes on average 7h 30m.
- Around 5 trains per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Brussels as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Brussels-Midi.
- Buses mostly depart from Karlsruhe Hbf and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus, Union Ivkoni International to go to Brussels by bus.
- Travel with Deutsche Bahn to go to Brussels by train.
- 1 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Karlsruhe to Brussels: related information
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