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Travel Information
Compare train and bus for Karlsruhe to Brussels
Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $50 For those with little time, consider booking a flight, which has an average total journey time of 3h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $50, while a flight costs an average of $625.
Distance: 219 miles (354 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$93 Average price | $50 Average price Cheapest | $625 Average price | $86 Average price (fuel + tolls) |
4h 53m Average total duration 4h 23m Onboard + 30m Additional time* | 9h 16m Average total duration 8h 46m Onboard + 30m Additional time* | 3h 5m Average total duration Fastest 1h 5m Onboard + 2h 0m Additional time* | 5h 30m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions | 1.1 - 2.1kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Karlsruhe to Brussels
Compare the available ways to get from Karlsruhe to Brussels, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Karlsruhe to Brussels:
A bus is $43 less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $93.
A bus is $575 less than a flight for this route with tickets for a flight from Karlsruhe to Brussels costing on average $625.
Other travel options to Brussels take longer:
Train takes on average 4h 53m.
Bus takes on average 9h 16m.
You'll arrive about 1h 7m sooner (4h 23m by train vs 5h 30m by car). Tickets start at around $93 compared to roughly $86 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Karlsruhe to Brussels
How to get from Karlsruhe to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Brussels is by taking a bus because it’s the best combination of price and speed.
- FlixBus · FlixBus8:55 AM9h50Karlsruhe Hbf6:45 PMSchaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)$521One-way1 transfer
Cheapest
- FlixBus · FlixBus8:55 AM9h50Karlsruhe Hbf6:45 PMSchaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)$521One-way1 transfer
Fastest
- ICE 202 · ICE 692 · ICE 168:59 AM4h27Karlsruhe Hbf1:26 PMBrussels-North$1751One-way2 transfers
Other options
- S6 · 4550 · ICE 183:25 AM6h10Karlsruhe9:35 AMBrussels-Midi$851One-way2 transfers
- ICE 376 · ICE 614 · ICE 167:59 AM5h36Karlsruhe Hbf1:35 PMBrussels-Midi$1081One-way2 transfers
- STR 3 · ICE 200 · ICE 31410:44 AM4h51Europaplatz/Post Galerie (Karlstraße)3:35 PMBrussels-Midi$1241One-way2 transfers
- FlixBus · FlixBus10:05 AM10h10Karlsruhe Hbf8:15 PMSchaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)$521One-way1 transfer
- FlixBus · FlixBus2:05 PM10h25Karlsruhe Hbf12:30 AMSchaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)$521One-way1 transfer
- FlixBus · FlixBus4:20 AM10h20Karlsruhe Hbf2:40 PMSchaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)$541One-way1 transfer
- ICE 204+
KL1818 · KL17056:59 AM7h41Karlsruhe Hbf2:40 PMBrussels Airport$3731One-way2 transfers - ICE 76 · ICE 1014+KL1818 · KL17056:37 AM8h03Karlsruhe Hbf2:40 PMBrussels Airport$3731One-way3 transfers
- ICE 202+KL1820 · KL17078:59 AM13h16Karlsruhe Hbf10:15 PMBrussels Airport$3761One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Karlsruhe to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Brussels.
This is compared to other travel options from Karlsruhe to Brussels:
A bus is $43 less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $93.
A bus is $575 less than a flight for this route with tickets for a flight from Karlsruhe to Brussels costing on average $625.
Other travel options to Brussels take longer:
Train takes on average 4h 53m.
Bus takes on average 9h 16m.
- Around 8 trains per day.
- Around 3 flights per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Brussels as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Brussels Airport.
- Trains mostly depart from Karlsruhe Hbf and arrive in Brussels-Midi.
- Buses mostly depart from Karlsruhe Hbf and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Brussels Airlines to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Deutsche Bahn, VIAS Rail GmbH to go to Brussels by train.
- 3 direct flights per day with Brussels Airlines.
Travelling from Karlsruhe to Brussels: related information
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