- Must visit
Reynolda House Museum of American Art
Museum of American art from colonial to modern periods, with changing exhibitions and a strong collection in Reynolda House.
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Winston Salem, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €44 For those with little time, consider booking a bus, which has an average total journey time of 4h 10m. Average ticket prices depend on the travel mode: a bus costs an average of €44, while a bus costs an average of €44.
Distance: 148 miles (239 km)
Most popular Bus | Driving |
|---|---|
€44 Average price Cheapest | €28 Average price (fuel + tolls) |
4h 10m Average total duration Fastest 3h 40m Onboard + 30m Additional time* | 2h 36m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around €44 compared to roughly €28 in fuel and tolls — a saving of about €-16.00. The journey takes 3h 40m versus 2h 36m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Buses from Greenville, SC to Winston Salem, NC run on average 2 times per day, taking around 3h 40m. Cheap bus tickets for this journey start at €28 if you book in advance.
There are 2 buses per day. The earliest bus runs at 06:55, the last at 18:17. The fastest bus covers the 148 miles (239 km) distance in 3h 35m.
Distance 148 miles (239 km) |
Average bus duration 3h 40m |
Cheapest ticket price €28 |
Buses per day 2 |
Direct buses 2 |
Fastest bus 3h 35m |
First bus 6:55 AM |
Last bus 6:17 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Apr - Jun |
Discover the best of Winston Salem, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Winston Salem, NC trip today.
Museum of American art from colonial to modern periods, with changing exhibitions and a strong collection in Reynolda House.
Living-history museum area with restored buildings, costumed interpretation, and exhibits on Moravian life in early Salem.
Children's museum with hands-on exhibits on science, careers, and play, designed for curious families and younger visitors.
Walkable historic district with brick sidewalks, restored structures, and museum sites that showcase Winston-Salem's Moravian roots.
Large urban park with trails, gardens, sports facilities, and open lawns popular for everyday recreation and seasonal events.
Downtown arts district known for galleries, murals, shops, and frequent public events in a compact, easy-to-explore area.
Find answers to the most common questions about traveling from Greenville, SC to Winston Salem, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Winston Salem, NC, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Winston Salem, NC buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Winston Salem, W 5th St (Greyhound Bus Station) station pair. Use this guide to compare Greenville, SC and Winston Salem, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
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