The cheapest and fastest buses from Detroit, MI to Winston Salem, NC
Cheapest price
$148
Average price
$148
Fastest journey
14 h
Average duration
14 h
Buses per day
1
Distance
734 km
The best way to find a cheap bus ticket from Detroit, MI to Winston Salem, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Winston Salem, NC will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $148.
Of the 1 buses that leave Detroit, MI for Winston Salem, NC on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 734 km distance in an average of 14 h but if you time it right, some buses will get you there in just 14 h .
On Sun, Mar 22 the slowest buses will take 14 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Detroit, MI to Winston Salem, NC
Omio recommends booking the bus as it is the most popular option from Detroit, MI to Winston Salem, NC among Omio's users. If you are prioritising price take the bus with prices starting from $93. For those with little time consider booking a flight which can get you there in 4h 6m. The ticket price range depends on the travel mode: a bus costs an average of $93, and a flight costs an average of $341.
Distance: 456 miles (734 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$117 Average price Cheapest | $341 Average price |
14h 25m Average total duration 13h 55m Onboard + 30m Additional time* | 7h 6m Average total duration Fastest 4h 6m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Detroit, MI to Winston Salem, NC bus times
The table below shows live departures for Detroit, MI to Winston Salem, NC buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 PM Detroit, MI | 14h00 | 10:15 AM Winston Salem, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Detroit, MI to Winston Salem, NC by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Detroit, MI to Winston Salem, NC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Detroit, MI to Winston Salem, NC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Detroit, MI to Winston Salem, NC.
Journey information
Overview: Bus from Detroit, MI to Winston Salem, NC
Buses from Detroit, MI to Winston Salem, NC run on average 2 times per day, taking around 13h 55m. Cheap bus tickets for this journey start at $93 (€75) if you book in advance.
There are 1 buses per day. The earliest bus runs at 05:00, the last at 23:55. The fastest bus covers the 456 miles (734 km) distance in 13h 55m.
Distance 456 miles (734 km) |
Average bus duration 13h 55m |
Cheapest ticket price $93 (€75) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 13h 55m |
First bus 05:00 |
Last bus 23:55 |
Bus providers: Greyhound from Detroit, MI to Winston Salem, NCYou can travel by bus between Detroit, MI to Winston Salem, NC with Greyhound for as low as $93 (€75). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Detroit, MI to Winston Salem, NC
Find answers to the most common questions about traveling from Detroit, MI to Winston Salem, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Winston Salem, NC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Detroit, MI to Winston Salem, NC
Most popular bus connections from Detroit, MI
More options for your journey from Detroit, MI to Winston Salem, NC
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