- Must visit
Reynolda House Museum of American Art
Museum of American art from colonial to modern periods, with changing exhibitions and a strong collection in Reynolda House.
Cheapest price on Sep 20
€120
Average ticket price on Sep 20
€120
Fastest journey on Sep 20
14 h
Average journey duration on Sep 20
14 h
Buses on Sep 20
1
Distance
734 km
The best way to find a cheap bus ticket from Detroit, MI to Winston Salem, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Winston Salem, NC will cost around €120 if you buy it on the day, but the cheapest tickets can be found for only €120.
On Sun, Sep 20, we found 1 buses from Detroit, MI to Winston Salem, NC, including 1 direct services.
On Sun, Sep 20 the direct buses cover the 734 km distance in an average of 14 h but if you time it right, some buses will get you there in just 14 h .
On Sun, Sep 20 the slowest buses will take 14 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Detroit, MI to Winston Salem, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €121 For those with little time, consider booking a bus, which has an average total journey time of 18h 55m. Average ticket prices depend on the travel mode: a bus costs an average of €121, while a bus costs an average of €121.
Distance: 456 miles (734 km)
Most popular Bus | Driving |
|---|---|
€121 Average price Cheapest | €94 Average price (fuel + tolls) |
18h 55m Average total duration Fastest 18h 25m Onboard + 30m Additional time* | 9h 3m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
This is compared to other travel options from Detroit, MI to Winston Salem, NC:
A bus is €385 less than a flight for this route with tickets for a flight from Detroit, MI to Winston Salem, NC costing on average €505.
Other travel options to Winston Salem, NC take longer:
Bus takes on average 18h 25m.
Tickets start at around €121 compared to roughly €94 in fuel and tolls — a saving of about €-26.76. The journey takes 18h 25m versus 9h 3m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 02:15PM | Duration 14h00 | Departure days Wed, Thu, Fri | Cheapest price €82 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 03:15PM | Duration 14h00 | Departure days Wed, Fri | Cheapest price €77 |
Operator Greyhound USA | Departure Time 08:15PM | Arrival Time 10:15AM | Duration 14h00 | Departure days Fri, Sat, Sun | Cheapest price €120 |
The table below shows live departures for Detroit, MI to Winston Salem, NC buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 PM Detroit, MI | 14h00 | 10:15 AM Winston Salem, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Detroit, MI to Winston Salem, NC run on average 2 times per day, taking around 18h 25m. Cheap bus tickets for this journey start at €71 but you can travel from only €71 by flight.
There are 1 buses per day. The earliest bus runs at 05:00, the last at 23:55. The fastest bus covers the 456 miles (734 km) distance in 14h 0m.
Distance 456 miles (734 km) |
Average bus duration 18h 25m |
Cheapest ticket price €71 |
Buses per day 2 |
Direct buses 1 |
Fastest bus 14h 0m |
First bus 5:00 AM |
Last bus 11:55 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Winston Salem, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Winston Salem, NC trip today.
Museum of American art from colonial to modern periods, with changing exhibitions and a strong collection in Reynolda House.
Living-history museum area with restored buildings, costumed interpretation, and exhibits on Moravian life in early Salem.
Children's museum with hands-on exhibits on science, careers, and play, designed for curious families and younger visitors.
Walkable historic district with brick sidewalks, restored structures, and museum sites that showcase Winston-Salem's Moravian roots.
Large urban park with trails, gardens, sports facilities, and open lawns popular for everyday recreation and seasonal events.
Downtown arts district known for galleries, murals, shops, and frequent public events in a compact, easy-to-explore area.
Find answers to the most common questions about traveling from Detroit, MI to Winston Salem, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Winston Salem, NC, this guide helps you travel smarter and with confidence.

Most Detroit, MI to Winston Salem, NC buses use the Detroit, Greyhound Terminal to Winston Salem, W 5th St (Greyhound Bus Station) station pair. Use this guide to compare Detroit, MI and Winston Salem, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Winston Salem, W 5th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Winston Salem, W 5th St (Greyhound Bus Station). ATMs are aTM available near ticket office.
Ticket office support is available at Winston Salem, W 5th St (Greyhound Bus Station).
Available at Winston Salem, W 5th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Winston Salem, W 5th St (Greyhound Bus Station): Station accessible for disabled passengers with ramps.
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