The cheapest and fastest buses from Detroit, MI to Winston Salem, NC
Cheapest price
$228
Average price
$228
Fastest journey
13 h 55 m
Average duration
13 h 55 m
Buses per day
1
Distance
734 km
The best way to find a cheap bus ticket from Detroit, MI to Winston Salem, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Winston Salem, NC will cost around $228 if you buy it on the day, but the cheapest tickets can be found for only $228.
Of the 1 buses that leave Detroit, MI for Winston Salem, NC on Thu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct buses cover the 734 km distance in an average of 13 h 55 m but if you time it right, some buses will get you there in just 13 h 55 m .
On Thu, Feb 05 the slowest buses will take 13 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Compare prices and tickets Detroit, MI to Winston Salem, NC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
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Why should you book Detroit, MI to Winston Salem, NC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Detroit, MI to Winston Salem, NC.
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Why book with Omio over Wanderu?
Journey information
Overview: Bus from Detroit, MI to Winston Salem, NC
Buses from Detroit, MI to Winston Salem, NC run on average 2 times per day, taking around 13h 55m. Cheap bus tickets for this journey start at $231 (€184) if you book in advance.
There are 1 buses per day. The earliest bus runs at 06:40, the last at 20:15. The fastest bus covers the 456 miles (734 km) distance in 13h 55m.
Distance 456 miles (734 km) |
Average bus duration 13h 55m |
Cheapest ticket price $231 (€184) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 13h 55m |
First bus 06:40 |
Last bus 20:15 |
Bus providers: Greyhound from Detroit, MI to Winston Salem, NCYou can travel by bus between Detroit, MI to Winston Salem, NC with Greyhound for as low as $231 (€184). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Detroit, MI to Winston Salem, NC
Find answers to the most common questions about traveling from Detroit, MI to Winston Salem, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Winston Salem, NC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Detroit, MI to Winston Salem, NC
Most popular bus connections from Detroit, MI
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