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Journey information
Overview: Bus from San Diego, CA to Knoxville, TN
USAUSA
Take a bus from San Diego, CA to Knoxville, TN and enjoy the approximately 1900 miles (3058 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 18:15, the last at 22:50.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1900 miles (3058 km) |
Average bus duration 48h 35m |
Buses per day 6 |
First bus 18:15 |
Last bus 22:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Diego, CA to Knoxville, TNYou can travel by bus between San Diego, CA to Knoxville, TN with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from San Diego, CA to Knoxville, TN
Find answers to the most common questions about traveling from San Diego, CA to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
The first bus from San Diego, CA to Knoxville, TN leaves at 6: 30AM. Plan your trip with the Journey Planner from Omio.
The last bus from San Diego, CA to Knoxville, TN leaves at 11: 45PM.
There are 4 buses a day from San Diego, CA to Knoxville, TN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
For the trip from San Diego, CA to Knoxville, TN you can take a bus with Greyhound. Be sure to check out all possible bus providers that offer services to Knoxville, TN from San Diego, CA on Omio to compare what amenities they may have.
A day trip to Knoxville, TN from San Diego, CA is worth doing with a journey time of min each way. Check with Omio app the best way to travel.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Knoxville, TN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Knoxville, TN for bus company Greyhound.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to Knoxville, TN depends on the bus company:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from San Diego, CA to Knoxville, TN, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from San Diego, CA to Knoxville, TN.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Knoxville, TN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Knoxville, TN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Knoxville, TN.
You can reserve your seat on the bus from San Diego, CA to Knoxville, TN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Knoxville, TN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Knoxville, TN with the following bus company: Greyhound.
popular bus stations
Popular bus stations from San Diego, CA to Knoxville, TN
San Diego
Knoxville
The major bus station for departures in San Diego is San Diego, San Ysidro Transit Center. Find all the information you need to know about services, amenities and connections at San Diego, San Ysidro Transit Center for your trip from San Diego to Knoxville.
San Diego, San Ysidro Transit Center
information
San Diego, Congress Street (Old Town Park)
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San Diego, West Harbor Drive (The Headquarters at Seaport District)
information
The major bus station for arrivals in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip to Knoxville from San Diego.
Knoxville, Kirkwood Street
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More options for your journey from San Diego, CA to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and San Diego, CA
Most popular bus connections to Knoxville, TN
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