4.9
4.6
Travel Information
Compare bus and flight for San Diego, CA to Knoxville, TN
Omio recommends booking the bus as it is the most popular option from San Diego, CA to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $257. For those with little time consider booking a flight which can get you there in 7h 45m. The ticket price range depends on the travel mode: a bus costs an average of $257, and a flight costs an average of $402.
Distance: 1900 miles (3058 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$257 Average price Cheapest | $402 Average price | $436 Average price (fuel + tolls) |
49h 5m Average total duration 48h 35m Onboard + 30m Additional time* | 10h 45m Average total duration Fastest 7h 45m Onboard + 3h 0m Additional time* | 31h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to Knoxville, TN:
A bus is $145 (€119) less than a flight for this route with tickets for a flight from San Diego, CA to Knoxville, TN costing on average $402 (€329).
Other travel options to Knoxville, TN take longer:
Bus takes on average 48h 35m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Diego, CA to Knoxville, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:35AM | Arrival Time 12:30AM | Duration 68h55 | Departure days Sat | Cheapest price $257 |
Compare prices and tickets San Diego, CA to Knoxville, TN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 18
Aug 19
Aug 20
Aug 21
Aug 22
Aug 23
Aug 24
Why should you book San Diego, CA to Knoxville, TN buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from San Diego, CA to Knoxville, TN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from San Diego, CA to Knoxville, TN.
Journey information
Overview: Bus from San Diego, CA to Knoxville, TN
USAUSA
Buses from San Diego, CA to Knoxville, TN run on average 7 times per day, taking around 48h 35m. Cheap bus tickets for this journey start at $257 (€210) if you book in advance.
The earliest bus runs at 07:35, the last at 22:50. The fastest bus covers the 1900 miles (3058 km) distance in 68h 55m.
Distance 1900 miles (3058 km) |
Average bus duration 48h 35m |
Cheapest ticket price $257 (€210) |
Buses per day 7 |
Fastest bus 68h 55m |
First bus 7:35 AM |
Last bus 10:50 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Bus providers: Greyhound from San Diego, CA to Knoxville, TNYou can travel by bus between San Diego, CA to Knoxville, TN with Greyhound for as low as $257 (€210). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Diego, CA to Knoxville, TN
Find answers to the most common questions about traveling from San Diego, CA to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Diego, CA to Knoxville, TN
Most San Diego, CA to Knoxville, TN buses use the San Diego, Congress Street (Old Town Park) to Knoxville, Kirkwood Street station pair. Use this guide to compare San Diego, CA and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which San Diego, CA station do buses to Knoxville, TN leave from?
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Which Knoxville, TN station do buses from San Diego, CA arrive at?
Getting to Knoxville, Kirkwood Street from Knoxville city centre
Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:
Knoxville, Kirkwood Street bus station facilities and services
Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.
Tickets and information
Ticket office support is available at Knoxville, Kirkwood Street.
Parking, taxis and toilets
Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.
More options for your journey from San Diego, CA to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and San Diego, CA
Most popular bus connections to Knoxville, TN
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
