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Travel Information
Compare bus and flight for San Diego, CA to Knoxville, TN
Omio recommends booking the bus as it is the most popular option from San Diego, CA to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $259. For those with little time consider booking a flight which can get you there in 7h 45m. The ticket price range depends on the travel mode: a bus costs an average of $259, and a flight costs an average of $406.
Distance: 1900 miles (3058 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$259 Average price Cheapest | $406 Average price |
49h 5m Average total duration 48h 35m Onboard + 30m Additional time* | 10h 45m Average total duration Fastest 7h 45m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets San Diego, CA to Knoxville, TN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Diego, CA to Knoxville, TN buses with Omio?
Greyhound operates all buses services from San Diego, CA to Knoxville, TN.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Knoxville, TN.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from San Diego, CA to Knoxville, TN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from San Diego, CA to Knoxville, TN.
Journey information
Overview: Bus from San Diego, CA to Knoxville, TN
USAUSA
Buses from San Diego, CA to Knoxville, TN run on average 7 times per day, taking around 48h 35m. Cheap bus tickets for this journey start at $259 (€210) if you book in advance.
The earliest bus runs at 07:35, the last at 22:50. The fastest bus covers the 1900 miles (3058 km) distance in 68h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1900 miles (3058 km) |
Average bus duration 48h 35m |
Cheapest ticket price $259 (€210) |
Buses per day 7 |
Fastest bus 68h 55m |
First bus 07:35 |
Last bus 22:50 |
Cheapest month Sep |
Cheapest day Sat |
High season Jan - Mar |
Low season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Diego, CA to Knoxville, TNYou can travel by bus between San Diego, CA to Knoxville, TN with Greyhound for as low as $259 (€210). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
68h 55m
Cheapest Price
$259 (€210)
Greyhound frequency
7 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from San Diego, CA to Knoxville, TN
Find answers to the most common questions about traveling from San Diego, CA to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Diego, CA to Knoxville, TN can start from as little as $259 (€210) when you book in advance. The average bus ticket price for San Diego, CA to Knoxville, TN is $259 (€210) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Knoxville, TN is 68h 55m to travel the 1900 miles (3058 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Knoxville, TN leaves at 7:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Knoxville, TN leaves at 10:50 PM.
There are 7 buses a day from San Diego, CA to Knoxville, TN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Knoxville, TN, you can count on Greyhound for the best way to get you to Knoxville, TN. You can also check all possible bus companies who offer a service between San Diego, CA and Knoxville, TN and compare the amenities they offer before buying a bus ticket.
A trip to Knoxville, TN from San Diego, CA is worth doing but not as a day trip with a journey time of 68h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Knoxville, TN is September.
It's helpful to compare your options as there are 2 ways to travel between San Diego, CA and Knoxville, TN including taking a bus and flight.
Yes, there are bathrooms on board the bus from San Diego, CA to Knoxville, TN for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Knoxville, TN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from San Diego, CA to Knoxville, TN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Knoxville, TN.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Knoxville, TN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Knoxville, TN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Knoxville, TN.
You can reserve your seat on the bus from San Diego, CA to Knoxville, TN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Knoxville, TN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Knoxville, TN with the following bus company: Greyhound.
popular bus stations
Popular bus stations from San Diego, CA to Knoxville, TN
San Diego
Knoxville
The major bus station for departures in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip from San Diego to Knoxville.
San Diego, Congress Street (Old Town Park)
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San Diego, San Ysidro Transit Center
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San Diego, West Harbor Drive (The Headquarters at Seaport District)
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The major bus station for arrivals in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip to Knoxville from San Diego.
Knoxville, Kirkwood Street
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More options for your journey from San Diego, CA to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and San Diego, CA
Most popular bus connections to Knoxville, TN
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