- Recommended
East Tennessee History Center
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
Buses from Los Angeles, CA to Knoxville, TN run on average 3 times per day, taking around 47h 16m. Cheap bus tickets for this journey start at ₫3,018,341 if you book in advance.
The earliest bus runs at 00:25, the last at 22:50. The fastest bus covers the 1936 miles (3117 km) distance in 43h 45m.
Distance 1936 miles (3117 km) |
Average bus duration 47h 16m |
Cheapest ticket price ₫3,018,341 |
Buses per day 3 |
Fastest bus 43h 45m |
First bus 12:25 AM |
Last bus 10:50 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Los Angeles, CA to Knoxville, TN.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:55PM | Arrival Time 01:50AM | Duration 53h55 | Departure days Sun | Cheapest price ₫3,018,624 |
The table below shows live departures for Los Angeles, CA to Knoxville, TN buses for today, Sunday, November 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:55 PM Los Angeles, CA | 53h55 | 1:50 AM Knoxville, TN | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of Knoxville, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Knoxville, TN trip today.
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
University museum featuring changing exhibitions of American and international art in a modern gallery setting near campus.
Historic house museum preserving the home of artist Adelia Armstrong Lutz, with decorative arts, local history, and period rooms.
Lively pedestrian-friendly square lined with shops, events, and public seating. It is a central gathering place and a great base for exploring downtown.
Urban park from the 1982 World's Fair with lawns, walking paths, performance spaces, and easy access to the Sunsphere and museums.
Historic warehouse district with brick streets, galleries, murals, and nightlife. It blends railroad-era character with a creative local feel.
Smoky pulled pork barbecue is a regional staple in East Tennessee, usually hickory-smoked and served with slaw and sauce at local cookouts and barbecue joints.
Fried catfish is a longtime Tennessee favorite, coated in cornmeal and served with hush puppies or sides, especially popular in casual Southern eateries.
Biscuits with sausage gravy are a classic Southern breakfast in Knoxville, featuring flaky biscuits topped with rich peppery gravy made with pork drippings and milk.
Long-running neighborhood restaurant known for hearty Southern comfort food, pies, and a warm, traditional dining room.
Upscale Southern restaurant in Market Square known for shrimp and grits, steaks, and a polished downtown atmosphere.
Casual old-school barbecue spot serving hickory-smoked pork, ribs, and classic East Tennessee sides in a relaxed setting.
Moderate for U.S. city breaks: hotels and dining are reasonable, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee is appreciated at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Knoxville, TN.
Find answers to the most common questions about traveling from Los Angeles, CA to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

Most Los Angeles, CA to Knoxville, TN buses use the Los Angeles, Patsaouras Transit Plaza (Union Station) to Knoxville, Kirkwood Street station pair. Use this guide to compare Los Angeles, CA and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food court and various dining options available.
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
Los Angeles, Gayley / Strathmore is 19 km from Los Angeles city centre. Public transport options include:
Los Angeles, Gayley / Strathmore has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Los Angeles, Gayley / Strathmore. ATMs are available at Los Angeles, Gayley / Strathmore.
Ticket office support is available at Los Angeles, Gayley / Strathmore.
Available at Los Angeles, Gayley / Strathmore: Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Gayley / Strathmore: Basic accessibility features available for buses.
Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:
Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.
Ticket office support is available at Knoxville, Kirkwood Street.
Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.
Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.
Check bus stations information for Los Angeles, CA and Knoxville, TN, including where buses depart and arrive on this route.
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