- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
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Cincinnati, OH to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 04:10PM | Duration 15h15 | Departure days Mon, Tue, Fri, Sat | Cheapest price $115 |
Operator Greyhound | Departure Time 10:25AM | Arrival Time 03:15AM | Duration 16h50 | Departure days Mon, Tue, Fri, Sat | Cheapest price $106 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 10:40AM | Duration 21h00 | Departure days Mon, Fri, Sat | Cheapest price $107 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 03:15AM | Duration 13h20 | Departure days Mon, Tue, Fri, Sat | Cheapest price $106 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 10:40AM | Duration 20h40 | Departure days Mon, Fri, Sat | Cheapest price $107 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 12:00PM | Duration 21h50 | Departure days Fri, Sat | Cheapest price $120 |
Operator Greyhound | Departure Time 03:00PM | Arrival Time 12:00PM | Duration 21h00 | Departure days Mon, Fri, Sat | Cheapest price $120 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 02:35PM | Duration 21h05 | Departure days Mon, Tue, Fri, Sat | Cheapest price $104 |
Live departures
Cincinnati, OH to Greenville, SC bus times
The table below shows live departures for Cincinnati, OH to Greenville, SC buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 · · · | 5:30 PM Cincinnati, Greyhound Bus Station, OH | 21h05 | 2:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Journey information
Overview: Bus from Cincinnati, OH to Greenville, SC
USAUSA
Take a bus from Cincinnati, OH to Greenville, SC and enjoy the approximately 316 miles (509 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 00:55, the last at 22:15.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 316 miles (509 km) |
Buses per day 4 |
First bus 12:55 AM |
Last bus 10:15 PM |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Greenville
Things to do in Greenville
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
- Recommended
Upcountry History Museum
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
- Recommended
Sigal Music Museum
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
- Must visit
Main Street
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
- Must visit
Falls Park on the Reedy
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
- Must visit
Swamp Rabbit Trail
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
- Gluten-free
South Carolina Barbecue
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
- Vegetarian
Fried Green Tomatoes
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
- Gluten-free
Shrimp And Grits
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
The Anchorage
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
Soby's
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Smoke On The Water
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
United States Dollar
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual restaurant.
- Fine dining
- USD 50-100+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a coffee drink.
Tipping culture
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
FAQs: Bus from Cincinnati, OH to Greenville, SC
Find answers to the most common questions about traveling from Cincinnati, OH to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
The earliest bus from Cincinnati, OH to Greenville, SC leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Cincinnati, OH to Greenville, SC leaves at 10:15 PM.
The cheapest month for a bus from Cincinnati, OH to Greenville, SC is August.
Yes, you can take a between Cincinnati, OH and Greenville, SC.
No, the bus from Cincinnati, OH to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Cincinnati, OH to Greenville, SC.
No, bikes are not allowed on board the bus from Cincinnati, OH to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Cincinnati, OH to Greenville, SC.
No, luggage for the bus from Cincinnati, OH to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Cincinnati, OH to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Cincinnati, OH to Greenville, SC.
No, there are no USB plugs on board the bus from Cincinnati, OH to Greenville, SC.
No, there is no WiFi on board the bus from Cincinnati, OH to Greenville, SC.
Since neither Cincinnati, OH nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Cincinnati, OH to Greenville, SC
Most Cincinnati, OH to Greenville, SC buses use the Cincinnati, Greyhound Bus Station to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Cincinnati, OH and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Cincinnati
Arrival bus stations in Greenville
Cincinnati, Greyhound Bus Station
City-centre transport
Getting to Cincinnati, Greyhound Bus Station from Cincinnati city centre
BusRoute B · 15m · $10
78 · 35m · $4 · every ~4 min
78 · 36m · $4 · every ~4 min
78 · 37m · $4 · every ~4 min
Cincinnati, Gilbert Ave (Greyhound Bus Station)
City-centre transport
Getting to Cincinnati, Gilbert Ave (Greyhound Bus Station) from Cincinnati city centre
Bus31 · 14m · $2 · every ~6 min
Cincinnati, Short Vine St (University of Cincinnati)
Greenville, Woodruff Rd ("Raceway" gas station)
Most popular bus connections from Cincinnati, OH
More options for your journey from Cincinnati, OH to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Cincinnati, OH
Most popular bus connections to Greenville, SC
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